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A multimodal approach identifies lactate as a central feature of right ventricular failure that is detectable in human plasma Hemnes, Anna; Fortune, Niki; Simon, Katie; Trenary, Irina A.; Shay, Sheila; Austin, Eric; Young, Jamey D.; Britain, Evan; West, James; Talati, Megha Share Save
Repetitive sulfur dioxide exposure in mice models post-deployment respiratory syndrome Gutor, Sergey S.; Salinas, Rodrigo I.; Nichols, David S.; Bazzano, Julia M. R.; Han, Wei; Gokey, Jason J.; Vasiukov, Georgii; West, James D.; Newcomb, Dawn C.; Dikalova, Anna E.; Richmond, Bradley W.; Dikalov, Sergey I.; Blackwell, Timothy S.; Polosukhin, Vasiliy V. Share Save
Activation of mTOR signaling in adult lung microvascular progenitor cells accelerates lung aging Mason, Emma C.; Menon, Swapna; Schneider, Benjamin R.; Gaskill, Christa F.; Dawson, Maggie M.; Moore, Camille M.; Armstrong, Laura Craig; Cho, Okyong; Richmond, Bradley W.; Kropski, Jonathan A.; West, James D.; Geraghty, Patrick; Gomperts, Brigitte N.; Ess, Kevin C.; Gally, Fabienne; Majka, Susan M. Share Save
Myeloid Cell Derived IL1β Contributes to Pulmonary Hypertension in HFpEF Agrawal, Vineet; Kropski, Jonathan A.; Gokey, Jason J.; Kobeck, Elizabeth; Murphy, Matthew B.; Murray, Katherine T.; Fortune, Niki L.; Moore, Christy S.; Meoli, David F.; Monahan, Ken; Ru Su, Yan; Blackwell, Thomas; Gupta, Deepak K.; Talati, Megha H.; Gladson, Santhi; Carrier, Erica J.; West, James D.; Hemnes, Anna R. Share Save
Myeloid Cell Derived IL1b Contributes to Pulmonary Vascular Remodeling in Heart Failure With Preserved Ejection Fraction Agrawal, Vineet; Kropski, Jon; Gokey, Jason J.; Kobeck, Elizabeth; Murphy, Matthew; Murray, Katherine T.; Fortune, Niki; Moore, Christy; Meoli, David; Monahan, Ken; Su, Yan Ru; Blackwell, Thomas; Gupta, Deepak K.; Talati, Megha; Gladson, Santhi; Carrier, Erica J.; West, James; Hemnes, Anna R. Share Save
CES1 Deficiency is Associated With Metabolic Reprograming and Endothelial Dysfunction in Pulmonary Arterial Hypertension Agarwal, Stuti; Heo, Lyong; Chakraborty, Ananya; Auer, Natasha; Swaminathan, Gowri; Liu, Lichao; West, James; Suresh, Karthik; Nair, Ramesh; Rabinovitch, Marlene; Nicolls, Mark; Morisseau, Christophe; Hammock, Bruce D.; Lafyatis, Robert; Kawut, Steven M.; Zamanian, Roham; Dejesus, Vinicio A. Share Save
A potential adverse role for leptin and cardiac leptin receptor in the right ventricle in pulmonary arterial hypertension: effect of metformin is BMPR2 mutation-specific Talati, Megha; Brittain, Evan; Agrawal, Vineet; Fortune, Niki; Simon, Katie; Shay, Sheila; Zeng, Xiaofang; Freeman, Michael L.; West, James; Hemnes, Anna Share Save
Development of a Peripherally Restricted 5-HT2B Partial Agonist for Treatment of Pulmonary Arterial Hypertension Valentine, Michael S.; Bender, Aaron M.; Shay, Sheila; Paffenroth, Krista C.; Gladson, Santhi; Dickerson, Jonathan W.; Watson, Katherine J.; Kapolka, Nicholas J.; Boutaud, Olivier; Rook, Jerri M.; Blackwell, Timothy S.; Roth, Bryan L.; Harrison, Fiona E.; Austin, Eric D.; West, James D.; Lindsley, Craig W.; Merryman, W. David Share Save
Molecular Function and Contribution of TBX4 in Development and Disease Karolak, Justyna A.; Welch, Carrie L.; Mosimann, Christian; Bzdega, Katarzyna; West, James D.; Montani, David; Eyries, Melanie; Mullen, Mary P.; Abman, Steven H.; Prapa, Matina; Graf, Stefan; Morrell, Nicholas W.; Hemnes, Anna R.; Perros, Frederic; Hamid, Rizwan; Logan, Malcolm P. O.; Whitsett, Jeffrey; Galambos, Csaba; Stankiewicz, Pawel; Chung, Wendy K.; Austin, Eric D. Share Save
The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice Kapitsinou, Pinelopi P.; Rajendran, Ganeshkumar; Astleford, Lindsay; Michael, Mark; Schonfeld, Michael P.; Fields, Timothy; Shay, Sheila; French, Jaketa L.; West, James; Haase, Volker H. Share Save
Thromboxane-Prostanoid Receptor Signaling Drives Persistent Fibroblast Activation in Pulmonary Fibrosis Suzuki, Toshio; Kropski, Jonathan A.; Chen, Jingyuan; Carrier, Erica J.; Chen, Xinping; Sherrill, Taylor P.; Winters, Nichelle, I; Camarata, Jane E.; Polosukhin, Vasiliy V.; Han, Wei; Rathinasabapathy, Anandharajan; Gutor, Sergey; Gulleman, Peter; Sabusap, Carleen; Banovich, Nicholas E.; Tanjore, Harikrishna; Freeman, Michael L.; Tada, Yuji; Young, Lisa R.; Gokey, Jason J.; Blackwell, Timothy S.; West, James D. Share Save
Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension (vol 124, pg 3514, 2014) Bertero, Thomas; Lu, Yu; Annis, Sofia; Hale, Andrew; Bhat, Balkrishen; Saggar, Rajan; Saggar, Rajeev; Wallace, W. Dean; Ross, David J.; Vargas, Sara O.; Graham, Brian B.; Kumar, Rahul; Black, Stephen M.; Fratz, Sohrab; Fineman, Jeffrey R.; West, James D.; Haley, Kathleen J.; Waxman, Aaron B.; Chau, B. Nelson; Cottrill, Katherine A.; Chan, Stephen Y. Share Save
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Mechanistic Phase II Clinical Trial of Metformin in Pulmonary Arterial Hypertension Brittain, Evan L.; Niswender, Kevin; Agrawal, Vineet; Chen, Xinping; Fan, Run; Pugh, Meredith E.; Rice, Todd W.; Robbins, Ivan M.; Song, Haocan; Thompson, Christopher; Ye, Fei; Yu, Chang; Zhu, He; West, James; Newman, John H.; Hemnes, Anna R. Share Save
Expression of a Human Caveolin-1 Mutation in Mice Drives Inflammatory and Metabolic Defect-Associated Pulmonary Arterial Hypertension Rathinasabapathy, Anandharajan; Copeland, Courtney; Crabtree, Amber; Carrier, Erica J.; Moore, Christy; Shay, Sheila; Gladson, Santhi; Austin, Eric D.; Kenworthy, Anne K.; Loyd, James E.; Hemnes, Anna R.; West, James D. Share Save
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Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling Summers, Megan E.; Richmond, Bradley W.; Menon, Swapna; Sheridan, Ryan M.; Kropski, Jonathan A.; Majka, Sarah A.; Taketo, M. Mark; Bastarache, Julie A.; West, James D.; De Langhe, Stijn; Geraghty, Patrick; Klemm, Dwight J.; Chu, Hong Wei; Friedman, Rachel S.; Tao, Yuankai K.; Foronjy, Robert F.; Majka, Susan M. Share Save
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