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J

Jonathan A. Javitch

Columbia University Vagelos College of Physicians and Surgeons

99H-index
430Paper Count
3.2WCitation Count
Published Papers 212
Publication Date
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Dopamine D2 receptors bypass canonical signaling to directly tune NMDA receptor function and aversive learning
errScience Advances
IF12.5
err2026-07-23
err0
errOAAI
errSheng Gong; Joy Adler; Ying Zhu; Charlize Szeto; Lisa Lin; Caroline Rauffenbart; Arturo Torres-Herraez; Wesley B. Asher; Jonathan A. Javitch; Christopher P. Ford
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CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk
errNature Communications
IF15.7
err2026-07-17
err0
errOAAI
errRoger B. Dodd; Masahiro Enomoto; Ye Zhou; Kanayo Satoh; Yalun Zhang; Fusheng Chen; Beatrice Acheson; Deniz Ghaffari; Elizabeth Sayn-Wittgenstein; Jamie J. Manning; George V. Dukas; Ronak Patel; Alondra Schweizer Burguete; Mason J. Kralovec; Mamunur Rashid; Jennifer L. Hall; Kirstin A. Tamucci; Zena Chatila; Minghua Liu; Annie J. Lee; Badri N. Vardarajan; Mariko F. Taga; Sirkku Pollari; Alon Rabinovitch; Cory D. Rillahan; Andrey A. Bobkov; Eduard Sergienko; William Meadows; Seema Qamar; Suzanne J. Randle; Christopher M. Johnson; Jean Sevalle; Jennifer Griffin; Christopher Bohm; Mitsuhiko Ikura; Xunde Xian; Joachim Herz; Megan A. Kelly; Jennifer West; Sandeep Satapathy; Mark R. Wilson; Jonathan A. Javitch; Paul E. Fraser; David A. Bennett; Philip L. De Jager; Zvi Fishelson; Dan Frenkel; Wesley B. Asher; Elizabeth M. Bradshaw; Peter St George-Hyslop
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errSave
Molecular Pharmacology of mGlu7/8 Heterodimers Reveals Unique Properties of Orthosteric Agonists and Positive Allosteric Modulators
errMolecular Pharmacology
IF3
err2026-06-06
err0
errOAAI
errAnthony S. Ferranti; Youhyun Noh; Xia Lei; Xin Lin; Joseph D. Bungard; Wesley B. Asher; Jonathan A. Javitch; Colleen M. Niswender
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errSave
Targeted inhibition of mu-opioid receptors in neuronal subpopulations by membrane-tethered Naloxo-DART antagonists
errCell Chemical Biology
IF7.2
err2025-12-03
err0
errOAAI
errJ. Sanchez; A. Bonifazi; S. Groom; M.O. Sambrook; G.A. Camacho-Hernandez; E.J. Kuijer; S. Karimi; K.U. Therese; M. Hauge Pedersen; C. Rauffenbart; M. Canals; A.H. Newman; C.P. Bailey; J.A. Javitch; J.R. Lane
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errSave
Parallel stopped-flow interrogation of diverse biological systems at the single-molecule scale
errNature Methods
IF32.1
err2025-12-02
err0
errOAAI
errRoman Kiselev; Ryan A. Brady; Arnab Modak; F. Aaron Cruz-Navarrete; Jose L. Alejo; Daniel S. Terry; Roger B. Altman; Wesley B. Asher; Jonathan A. Javitch; Scott C. Blanchard
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errSave
Mu Opioid Receptor Activation is Required for NMDA Receptor Antagonist Effects on Stress-induced Maladaptive Behavior
errBiological Psychiatry
IF9
err2025-07-07
err0
errOAAI
errCory B. Langreck; Briana Chen; Victor M. Luna; Mel Nelson; Gergely Turi; Rob Hill; Gilles Rubinstenn; Meritxell Canals; J. Robert Lane; Christine A. Denny; Jonathan A. Javitch
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errSave
Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D2 Receptor
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2025-05-15
err0
PREAI
errLim, Herman D.; Bartuzi, Damian; Keen, Alastair C.; Rauffenbart, Caroline; Glenn, Jacqueline; Charlton, Steven J.; Lovera, Silvia; Sands, Zara A.; Ates, Ali; Wood, Martyn; Canals, Meritxell; Javitch, Jonathan A.; Carlsson, Jens; Lane, J. Robert
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errSave
Chronic administration of methocinnamox, a mu-opioid receptor antagonist, reduces hedonic response without impacting motivation in mice
errPSYCHOPHARMACOLOGY
IF3.3
err2025-05-10
err0
PREAI
errSheikh, Misbah; Cambre, Emily; Langreck, Cory; Javitch, Jonathan A.; Canetta, Sarah E.
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errSave
Complex G-protein signaling of the adhesion GPCR, ADGRA3
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-05-01
err0
errOAAI
errBagger, Sofie M.; Schihada, Hannes; Walser, Anna L. S.; Drzazga, Anna K.; Gratz, Lukas; Palmisano, Tiago; Kuhn, Christina K.; Mavri, Masa; Molleskov-Jensen, Ann-Sophie; Tall, Gregory G.; Schoeneberg, Torsten; Mathiasen, Signe J.; Javitch, Jonathan A.; Schulte, Gunnar; Spiess, Katja; Rosenkilde, Mette M.
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errSave
N-terminal fragment shedding contributes to signaling of the full-length adhesion receptor ADGRL3
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-02-01
err0
PREAI
errPerry-Hauser, Nicole A.; Du Rand, Jonathan R.; Lee, Kuo Hao; Shi, Lei; Javitch, Jonathan A.
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errSave
Elucidating the molecular logic of a metabotropic glutamate receptor heterodimer
errNATURE COMMUNICATIONS
IF15.7
err2024-10-03
err0
errOAAI
errLin, Xin; Provasi, Davide; Niswender, Colleen M.; Asher, Wesley B.; Javitch, Jonathan A.
errShare
errSave
Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models
errNATURE COMMUNICATIONS
IF15.7
err2024-09-20
err0
errOAAI
errHavel, Vaclav; Kruegel, Andrew C.; Bechand, Benjamin; Mcintosh, Scot; Stallings, Leia; Hodges, Alana; Wulf, Madalee G.; Nelson, Mel; Hunkele, Amanda; Ansonoff, Michael; Pintar, John E.; Hwu, Christopher; Ople, Rohini S.; Abi-Gerges, Najah; Zaidi, Saheem A.; Katritch, Vsevolod; Yang, Mu; Javitch, Jonathan A.; Majumdar, Susruta; Hemby, Scott E.; Sames, Dalibor
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errSave
Molecular Design of SERTlight: A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-04-01
err1
PREAI
errLee, Wei-Li; Westergaard, Xavier; Hwu, Christopher; Hwu, Jennifer; Fiala, Tomas; Lacefield, Clay; Boltaev, Umed; Mendieta, Adriana M.; Lin, Lisa; Sonders, Mark S.; Brown, Keaon R.; He, Keer; Asher, Wesley B.; Javitch, Jonathan A.; Sulzer, David; Sames, Dalibor
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errSave
In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2024-02-12
err5
PREAI
errTsai, Meng-Hua M.; Chen, Li; Baumann, Michael H.; Canals, Meritxell; Javitch, Jonathan A.; Lane, J. Robert; Shi, Lei
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errSave
NEW POTENTIAL PHARMACOLOGICAL TARGETS FOR CHILDHOOD PSYCHIATRIC DISORDERS THROUGH DIFFERENTIAL MODULATION OF GLUTAMATE RECEPTORS
errJOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
IF9.5
err2023-10-01
err0
errOAAI
errSteinfeld, Justin B.; Lakhter, David; Javitch, Jonathan A.
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errSave
Assessment of the potential of novel and classical opioids to induce respiratory depression in mice
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2023-08-22
err6
errOAAI
errHill, Rob; Sanchez, Julie; Lemel, Laura; Antonijevic, Mirjana; Hosking, Yselkla; Mistry, Shailesh N.; Kruegel, Andrew C.; Javitch, Jonathan A.; Lane, J. Robert; Canals, Meritxell
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errSave
Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling (vol 28, pg 1960, 2023)
errMOLECULAR PSYCHIATRY
IF10.1
err2023-08-07
err1
errOAAI
errJobin, Marie-Lise; De Smedt-Peyrusse, Veronique; Ducrocq, Fabien; Baccouch, Rim; Oummadi, Asma; Pedersen, Maria Hauge; Medel-Lacruz, Brian; Angelo, Maria-Florencia; Villette, Sandrine; Van Delft, Pierre; Fouillen, Laetitia; Mongrand, Sebastien; Selent, Jana; Tolentino-Cortez, Tarson; Barreda-Gomez, Gabriel; Gregoire, Stephane; Masson, Elodie; Durroux, Thierry; Javitch, Jonathan A.; Guixa-Gonzalez, Ramon; Alves, Isabel D.; Trifilieff, Pierre
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errSave
A Novel Activation Switch Motif Common to All Aminergic Receptors
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2023-08-04
err4
errOAAI
errLee, Kuo Hao; Manning, Jamie J.; Javitch, Jonathan; Shi, Lei
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errSave
Free fatty acid receptor 1 stimulates cAMP production and gut hormone secretion through Gq-mediated activation of adenylate cyclase 2
errMOLECULAR METABOLISM
IF6.6
err2023-08-01
err6
errOAAI
errPetersen, Jacob Emil; Pedersen, Maria Hauge; Dmytriyeva, Oksana; Nellemose, Emilie; Arora, Tulika; Engelstoft, Maja Storm; Asher, Wesley B.; Javitch, Jonathan A.; Schwartz, Thue W.; Trauelsen, Mette
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errSave
Tianeptine promotes lasting antiallodynic effects in a mouse model of neuropathic pain
errNEUROPSYCHOPHARMACOLOGY
IF7.1
err2023-07-20
err4
PREAI
errSerafini, Randal. A. A.; Estill, Molly; Pekarskaya, Elizabeth. A. A.; Sakloth, Farhana; Shen, Li; Javitch, Jonathan. A. A.; Zachariou, Venetia
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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