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Jean‐Christophe Lega

Université de Lyon

34H-index
260Paper Count
5.1KCitation Count
Published Papers 72
Publication Date
The Erosion of Proof in Paradigm Transitions: The Rise of Narrative Rationality in Health Technology Assessment
err2026-08-11
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errJean-Christophe Lega; Arthur Gougeon; Claudina Michal; Steeve Provencher; Florian Naudet; Bruno Falissard; Sylvie Chevret; Remy Boussageon
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Changes in estimands and prevalence of discrepancies in conclusions under the two-trial paradigm: a systematic review
err2026-05-22
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errAlex Hlavaty; Clément Jambon-Barbara; Marc Manceau; Selin Keklik; Jean-Christophe Lega; Michel Cucherat; Charles Khouri; Matthieu Roustit
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Characteristics of patients with major relapse in giant cell arteritis: a multicenter case–control study
err2025-11-27
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PREAI
errAlice Rubinsztajn; Simon Parreau; Laurent Sailler; Hubert de Boysson; Olivier Espitia; Pascal Sève; Arnaud Hot; Laurent Perard; Jean-Christophe Lega; Sabine Mainbourg
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Reversing the burden of evidence: a needed evolution in GRADE to address publication bias
err2025-10-08
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PREAI
errA. Gougeon; J.C. Lega; B. Kassaï; F. Gueyffier; R. Boussageon; G. Grenet
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Temporal evolution of publication bias in drug safety assessment: A case study on association between osteonecrosis of the jaw and bisphosphonates
err2025-09-16
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PREAI
errNimetullah Aksoy; Guillaume Grenet; Maëlys Granal; Marine Auffret; François Gueyffier; Audrey Lajoinie; Jean-Christophe Lega; Emmanuel Massy; Arthur Gougeon
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How publication bias overestimates the risk of atypical femoral fracture and osteonecrosis of the jaw associated with bisphosphonate use: A meta-epidemiological study
err2025-02-01
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errGougeon, Arthur; Granal, Maelys; Massy, Emmanuel; Gueyffier, Francois; Lega, Jean-Christophe; Lajoinie, Audrey; Grenet, Guillaume
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Publication bias in pharmacogenetics of statin-associated muscle symptoms: A meta-epidemiological study
err2025-01-01
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errGougeon, A.; Aribi, I.; Guernouche, S.; Lega, J. C.; Wright, J. M.; Verstuyft, C.; Lajoinie, A.; Gueyffier, F.; Grenet, G.
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RETRACTION: 'Deaths induced by compassionate use of hydroxychloroquine during the first COVID-19 wave: an estimate
err2024-10-01
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errPradelle, Alexiane; Mainbourg, Sabine; Provencher, Steeve; Massy, Emmanuel; Grenet, Guillaume; Lega, Jean-Christophe
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Risk of infections in psoriatic arthritis or axial spondyloarthritis patients treated with targeted therapies: A meta-analysis of randomized controlled trials*
err2024-05-01
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PREAI
errSeauve, Milene; Aureal, Melanie; Laplane, Soline; Lega, Jean-Christophe; Cabrera, Natalia; Coury, Fabienne
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Comparison of daptomycin and glycopeptide efficacy and safety for the treatment of Gram-positive infections: a systematic review and meta-analysis
err2024-02-07
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errBoulekbache, Abdelwahab; Maldonado, Fanny; Kavafian, Raphael; Ferry, Tristan; Bourguignon, Laurent; Goutelle, Sylvain; Lega, Jean-Christophe; Garreau, Romain
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Deaths induced by compassionate use of hydroxychloroquine during the first COVID-19 wave: an estimate
err2024-02-01
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errOAAI
errPradelle, Alexiane; Mainbourg, Sabine; Provencher, Steeve; Massy, Emmanuel; Grenet, Guillaume; Lega, Jean-Christophe
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Treatment strategy for acquired pure red cell aplasia: a systematic review and meta-analysis
err2023-10-26
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errLobbes, Herve; Lega, Jean-Christophe; Le Guenno, Guillaume; Ruivard, Marc; Mainbourg, Sabine
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Patients' perceptions on clinical trials outcomes in pulmonary arterial hypertension therapy
errTHORAX
IF7.7
err2023-05-04
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PREAI
errMai, Vicky; Gosselin, Camille; Tremblay, Elodie; Rompre, Gabrielle; Lajoie, Annie Christine; Weatherald, Jason; Lega, Jean-Christophe; Bonnet, Sebastien; Provencher, Steeve
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Infection Risk in Patients with Dermatomyositis Associated with Anti-MDA5 Antibodies: A Historical Cohort Study
err2022-12-08
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errBillet, Anne-Claire; Barba, Thomas; Coutant, Frederic; Fabien, Nicole; Perard, Laurent; Seve, Pascal; Lega, Jean-Christophe; Durel, Cecile-Audrey; Gallay, Laure; Hot, Arnaud
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Intravenous Immunoglobulins Tapering and Withdrawal in Systemic Capillary Leak Syndrome (Clarkson Disease)
err2022-11-01
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errMoyon, Quentin; Chambrun, Marc Pineton de; Gousseff, Marie; Mathian, Alexis; Hie, Miguel; Urbanski, Geoffrey; Verlicchi, Franco; Faguer, Stanislas; Dossier, Antoine; Lega, Jean-Christophe; Riviere, Sophie; Saadoun, David; Graveleau, Julie; Lucchini-Lecomte, Marie-Josee; Christides, Christine; Le Moal, Sylvie; Bibes, Beatrice; Malizia, Giuseppe; Ruivard, Marc; Blaison, Gilles; Alric, Laurent; Agard, Christian; Soubrier, Martin; Viallard, Jean-Francois; Levesque, Herve; Rivard, Georges-Etienne; Tieulie, Nathalie; Hot, Arnaud; Lovey, Pierre-Yves; Hanslik, Thomas; Lhote, Francois; Eble, Vincent; Troncoso, Jorge Alvarez; Aujayeb, Avinash; Quentric, Paul; Taieb, Dov; Cohen-Aubart, Fleur; Lambert, Marc; Amoura, Zahir; EureClark Study Grp
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Indirect Comparison of Glucocorticoid-Sparing Agents for Remission Maintenance in Giant Cell Arteritis: A Network Meta-analysis
err2022-10-01
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errMainbourg, Sabine; Tabary, Axel; Cucherat, Michel; Gueyffier, Francois; Lobbes, Herve; Aussedat, Marie; Grenet, Guillaume; Durieu, Isabelle; Samson, Maxime; Lega, Jean Christophe
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Serological response to SARS-CoV-2 vaccination in patients with inflammatory rheumatic disease treated with disease modifying anti-rheumatic drugs: A cohort study and a meta-analysis
err2022-10-01
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errAuroux, Maxime; Laurent, Benjamin; Coste, Baptiste; Massy, Emmanuel; Mercier, Alexandre; Durieu, Isabelle; Confavreux, Cyrille B.; Lega, Jean-Christophe; Mainbourg, Sabine; Coury, Fabienne
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Assessment of Clinical Worsening End Points as a Surrogate for Mortality in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
err2022-08-23
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errTremblay, Elodie; Gosselin, Camille; Mai, Vicky; Lajoie, Annie C.; Kilo, Roubi; Weatherald, Jason; Lacasse, Yves; Bonnet, Sebastien; Lega, Jean-Christophe; Provencher, Steeve
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SGLT2 inhibitors in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials balancing their risks and benefits
err2022-08-04
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errMarilly, Elisa; Cottin, Judith; Cabrera, Natalia; Cornu, Catherine; Boussageon, Remy; Moulin, Philippe; Lega, Jean-Christophe; Gueyffier, Francois; Cucherat, Michel; Grenet, Guillaume
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Human Papilloma Virus Vaccination in Patients with Rheumatic Diseases in France: A Study of Vaccination Coverage and Drivers of Vaccination
err2022-07-16
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errDavid, Emmanuelle; Roy, Pascal; Belot, Alexandre; Quartier, Pierre; Meunier, Brigitte Bader; Aeschlimann, Florence A.; Lega, Jean-Christophe; Durieu, Isabelle; Rousset-Jablonski, Christine
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