Patrik Rorsman - Publications, H-index & Citations

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Patrik Rorsman

university of oxford

104H-index

442Paper Count

3.8WCitation Count

Published Papers 169

Publication Date

Metabolic state determines the brain and direct islet effects of liraglutide on enhanced insulin secretion

Diabetologia

IF10.2

2026-06-25

PREAI

Chiara Saponaro; Monica Imbernon; Isaline Louvet; Eleonora Deligia; Shiqian Chen; Iona Davies; Ana Acosta-Montalvo; Maria Moreno-Lopez; Eve Wemelle; Lakshmi Kothegala; Begoña Porteiro; Florent Auger; Lorea Zubiaga; Nathalie Dellalau; Julien Thevenet; Markus Mühlemann; Gianni Pasquetti; Valery Gmyr; Frank W. Pfrieger; Ruben Nogueiras; Markus Schwaninger; Patrik Rorsman; Bart Staels; Julie Kerr-Conte; Claude Knauf; Ben Jones; François Pattou; Vincent Prevot; Caroline Bonner

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Partial restoration of counterregulatory circulating glucagon by dapagliflozin and low-dose glibenclamide in men with type 1 diabetes: in vitro studies and randomised clinical crossover trial

EBioMedicine

IF10.8

2026-05-19

OAAI

Rui Gao; Ioannis Spiliotis; Haiqiang Dou; Thomas G. Hill; Lakshmi Kothegala; Caroline Miranda; Nkemjika Abiakam; Ruth L. Coleman; Sarah White; Amanda Adler; Patrik Rorsman

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Stephen Ashcroft, 27 January 1942–28 November 2025

Diabetologia

IF10.2

2026-02-21

PREAI

Frances Ashcroft; Richard M. Denton; Patrik Rorsman; Guy A. Rutter

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Antecedent hypoglycaemia impairs glucagon secretion by enhancing somatostatin-mediated negative feedback control

Nature Metabolism

IF20.8

2026-01-13

PREAI

Rui Gao; Samuel Acreman; Haiqiang Dou; Jinfang Ma; Caroline Miranda; Ruiling Zhao; Matthew T. Dickerson; Andrei Tarasov; Qi Zou; Marta Gironella-Torrent; Johan Tolö; Anne Clark; Rui Gao; Yang De Marinis; David A. Jacobson; Joan Camunas-Soler; Tao Yang; Patrik Rorsman; Quan Zhang

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Single Fusion Pore Analysis via Single Cell Amperometry Uncovers Impaired Pore Expansion That Restricts Insulin Exocytosis in Human Type 2 Diabetes

Angewandte Chemie International Edition

IF0

2025-09-25

OAAI

Dr. Amir Hatami; Dr. Nikhil R. Gandasi; Dr. Haiqiang Dou; Dr. Lakshmi Kothegala; Lena Eliasson; Prof. Andrew Ewing; Prof. Patrik Rorsman

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HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes

Cell Metabolism

IF30.9

2025-08-06

OAAI

Edgar Bernardo; Matías Gonzalo De Vas; Diego Balboa; Mirabai Cuenca-Ardura; Sílvia Bonàs-Guarch; Mercè Planas-Fèlix; Fanny Mollandin; Miquel Torrens-Dinarès; Miguel Angel Maestro; Javier García-Hurtado; Sonia Moratinos; Philippe Ravassard; Haiqiang Dou; Holger Heyn; Alexander van Oudenaarden; Nathalie Groen; Eelco de Koning; Christian Conrad; Roland Eils; Santiago Vernia; Patrik Rorsman; Jorge Ferrer

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Dehydration-induced AVP stimulates glucagon release and ketogenesis

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

IF3.1

2025-04-01

PREAI

Hill, TG; Briant, LJB; Kim, A; Wu, YL; Rorsman, P; Asterholm, IW; Benrick, A

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Nicotinic Signaling Stimulates Glucagon Secretion in Mouse and Human Pancreatic α-Cells

DIABETES

IF7.5

2024-10-30

PREAI

Hamilton, Alexander; Zhang, Quan; Gao, Rui; Hill, Thomas G.; Salehi, Albert; Knudsen, Jakob G.; Draper, Matthew B.; Johnson, Paul R. V.; Rorsman, Patrik; Tarasov, Andrei I.

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Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1 diabetes

NATURE METABOLISM

IF20.8

2024-09-23

OAAI

Hill, Thomas G.; Gao, Rui; Benrick, Anna; Kothegala, Lakshmi; Rorsman, Nils; Santos, Cristiano; Acreman, Samuel; Briant, Linford J.; Dou, Haiqiang; Gandasi, Nikhil R.; Guida, Claudia; Haythorne, Elizabeth; Wallace, Marsha; Knudsen, Jakob G.; Miranda, Caroline; Tolo, Johan; Clark, Anne; Davison, Lucy; Storling, Joachim; Tarasov, Andrei; Ashcroft, Frances M.; Rorsman, Patrik; Zhang, Quan

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Every islet matters: improving the impact of human islet research (vol 4, pg 970, 2022)

NATURE METABOLISM

IF20.8

2024-07-02

PREAI

Gloyn, Anna L.; Ibberson, Mark; Marchetti, Piero; Powers, Alvin C.; Rorsman, Patrik; Sander, Maike; Solimena, Michele

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An unclear role for the GLP-1 metabolite GLP-1(9-36) in human islet physiology. Reply to Matveyenko A, Vella A [letter]

DIABETOLOGIA

IF10.2

2024-04-05

PREAI

Gandasi, Nikhil R.; Rorsman, Patrik

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GLP-1 metabolite GLP-1(9-36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion

DIABETOLOGIA

IF10.2

2023-12-21

OAAI

Gandasi, Nikhil R.; Gao, Rui; Kothegala, Lakshmi; Pearce, Abigail; Santos, Cristiano; Acreman, Samuel; Basco, Davide; Benrick, Anna; Chibalina, Margarita V.; Clark, Anne; Guida, Claudia; Harris, Matthew; Johnson, Paul R. V.; Knudsen, Jakob G.; Ma, Jinfang; Miranda, Caroline; Shigeto, Makoto; Tarasov, Andrei I.; Yeung, Ho Yan; Thorens, Bernard; Asterholm, Ingrid W.; Zhang, Quan; Ramracheya, Reshma; Ladds, Graham; Rorsman, Patrik

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Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells

DIABETES

IF7.5

2023-07-26

OAAI

Armour, Sarah L.; Frueh, Alexander; Chibalina, Margarita V.; Dou, Haiqiang; Argemi-Muntadas, Lidia; Hamilton, Alexander; Katzilieris-Petras, Georgios; Carmeliet, Peter; Davies, Benjamin; Moritz, Thomas; Eliasson, Lena; Rorsman, Patrik; Knudsen, Jakob G.

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Platelet-derived lipids promote insulin secretion of pancreatic β cells

EMBO MOLECULAR MEDICINE

IF8.3

2023-07-25

OAAI

Karwen, Till; Kolczynska-Matysiak, Katarzyna; Gross, Carina; Loeffler, Mona C.; Friedrich, Mike; Loza-Valdes, Angel; Schmitz, Werner; Wit, Magdalena; Dziaczkowski, Filip; Belykh, Andrei; Trujillo-Viera, Jonathan; El-Merahbi, Rabih; Deppermann, Carsten; Nawaz, Sameena; Hastoy, Benoit; Demczuk, Agnieszka; Erk, Manuela; Wieckowski, Mariusz R.; Rorsman, Patrik; Heinze, Katrin G.; Stegner, David; Nieswandt, Bernhard; Sumara, Grzegorz

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Optogenetic Control of Pancreatic Delta Cells Reveals Their Central Role in Hormone Release from Pancreatic Islets

DIABETES

IF7.5

2023-06-20

PREAI

Dou, Haiqiang; Miranda, Caroline A.; Tolo, Johan; Zhang, Quan; Rorsman, Patrik

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Alpha-Cell Heterogeneity Contributes to Phasic Glucagon Release

DIABETES

IF7.5

2023-06-20

PREAI

Miranda, Caroline A.; Dou, Haiqiang; Tolo, Johan; Tarasov, Andrei I.; Rorsman, Patrik

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History of key regulatory peptide systems and perspectives for future research

JOURNAL OF NEUROENDOCRINOLOGY

IF4.1

2023-04-13

OAAI

Chen, Duan; Rehfeld, Jens F.; Watts, Alan G.; Rorsman, Patrik; Gundlach, Andrew L.

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Metabolic Messengers: glucagon

NATURE METABOLISM

IF20.8

2023-01-13

PREAI

MacDonald, Patrick E. E.; Rorsman, Patrik

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Hindbrain insulin controls feeding behavior

MOLECULAR METABOLISM

IF6.6

2022-12-01

OAAI

Eerola, Kim; Longo, Francesco; Reinbothe, Thomas M.; Richard, Jennifer E.; Shevchouk, Olesya T.; Lopez-Ferreras, Lorena; Mishra, Devesh; Asker, Mohammed; Tolo, Johan; Miranda, Caroline; Musovic, Saliha; Olofsson, Charlotta S.; Rorsman, Patrik; Skibicka, Karolina P.

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Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells

NATURE COMMUNICATIONS

IF15.7

2022-11-14

OAAI

Haythorne, Elizabeth; Lloyd, Matthew; Walsby-Tickle, John; Tarasov, Andrei, I; Sandbrink, Jonas; Portillo, Idoia; Exposito, Raul Terron; Sachse, Gregor; Cyranka, Malgorzata; Rohm, Maria; Rorsman, Patrik; McCullagh, James; Ashcroft, Frances M.

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Research Directions