Not logged inGenome-wide CRISPR screen identifies ACSL3 as a regulator of lipotoxicity and progression of MASLD
Myojin, Yuta; Kodama, Takahiro; Takahashi, Ryo; Nagasawa, Hideharu; Kondo, Yasuteru; Yusa, Kosuke; Yoshida-Hashidate, Tomomi; Shindou, Hideo; Furuta, Kunimaro; Murai, Kazuhiro; Saito, Yoshinobu; Hikita, Hayato; Takehara, Tetsuo .png)
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SaveShare Save CAR T or NK cells targeting mismatched HLA-DR molecules in acute myeloid leukemia after allogeneic hematopoietic stem cell transplantIkeda, Shunya; Hasegawa, Kana; Kogue, Yosuke; Arimori, Takao; Kawamoto, Ryuhei; Wibowo, Tansri; Yaga, Moto; Inada, Yuri; Uehara, Hirofumi; Matsubara, Miwa; Tachikawa, Mana; Suga, Makiko; Kida, Shuhei; Shibata, Kumi; Tsutsumi, Kazuhito; Fukushima, Kentaro; Fujita, Jiro; Ueda, Tomoaki; Kusakabe, Shinsuke; Hino, Akihisa; Ichii, Michiko; Hirose, Asao; Nakamae, Hirohisa; Hino, Masayuki; Nakao, Takafumi; Inoue, Megumu; Yoshihara, Kyoko; Yoshihara, Satoshi; Ueda, Shuji; Tachi, Tetsuro; Kuroda, Hideki; Murakami, Koki; Kijima, Noriyuki; Kishima, Haruhiko; Igashira, Eri; Murakami, Mari; Takiuchi, Tsuyoshi; Kimura, Tadashi; Hiroshima, Takashi; Kimura, Toru; Shintani, Yasushi; Imai, Chihaya; Yusa, Kosuke; Mori, Ryota; Ogino, Takayuki; Eguchi, Hidetoshi; Takeda, Kiyoshi; Oji, Yusuke; Kumanogoh, Atsushi; Takagi, Junichi Share Save Translational research of CDK12/13 inhibitor, CTX-439, informing clinical trial strategyYamakawa, Hiroko; Ebara, Shunsuke; Mizutani, Akio; Yoshida, Misaki; Sugiyama, Midori; Yamamoto, Koji; Komura, Daisuke; Kakiuchi, Miwako; Ishikawa, Shumpei; Yusa, Kosuke; Morishita, Daisuke Share Save RENGE infers gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbationsIshikawa, Masato; Sugino, Seiichi; Masuda, Yoshie; Tarumoto, Yusuke; Seto, Yusuke; Taniyama, Nobuko; Wagai, Fumi; Yamauchi, Yuhei; Kojima, Yasuhiro; Kiryu, Hisanori; Yusa, Kosuke; Eiraku, Mototsugu; Mochizuki, Atsushi Share Save Share Save Characterization of Sleeping Beauty transposition and its application to genetic screening in miceHorie, K; Yusa, K; Yae, K; Odajima, J; Fischer, SEJ; Keng, VW; Hayakawa, T; Mizuno, S; Kondoh, G; Ijiri, T; Matsuda, Y; Plasterk, RHA; Takeda, J Share Save Share Save Share Save Sleeping beauty transposon-based phenotypic analysis of mice:: Lack of Arpc3 results in defective trophoblast outgrowthYae, Kojiro; Keng, Vincent W.; Koike, Masato; Yusa, Kosuke; Kouno, Michiyoshi; Uno, Yoshihiro; Kondoh, Gen; Gotow, Takahiro; Uchiyama, Yasuo; Horie, Kyoji; Takeda, Junji Share Save Share Save B1 SINE-binding ZFP266 impedes mouse iPSC generation through suppression of chromatin opening mediated by reprogramming factorsKaemena, Daniel F.; Yoshihara, Masahito; Beniazza, Meryam; Ashmore, James; Zhao, Suling; Bertenstam, Marten; Olariu, Victor; Katayama, Shintaro; Okita, Keisuke; Tomlinson, Simon R.; Yusa, Kosuke; Kaji, Keisuke Share Save Pharmacologic characterization of TBP1901, a prodrug form of aglycone curcumin, and CRISPR-Cas9 screen for therapeutic targets of aglycone curcuminAbe, Tomoyuki; Horisawa, Yoshihito; Kikuchi, Osamu; Ozawa-Umeta, Hitomi; Kishimoto, Atsuhiro; Katsuura, Yasuhiro; Imaizumi, Atsushi; Hashimoto, Tadashi; Shirakawa, Kotaro; Takaori-Kondo, Akifumi; Yusa, Kosuke; Asakura, Tadashi; Kakeya, Hideaki; Kanai, Masashi Share Save Share Save AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitorsDunn, Shanade; Eberlein, Cath; Yu, Jason; Gris-Oliver, Albert; Ong, Swee Hoe; Yelland, Urs; Cureton, Natalie; Staniszewska, Anna; McEwen, Robert; Fox, Millie; Pilling, James; Hopcroft, Philip; Coker, Elizabeth A.; Jaaks, Patricia; Garnett, Mathew J.; Isherwood, Beverley; Serra, Violeta; Davies, Barry R.; Barry, Simon T.; Lynch, James T.; Yusa, Kosuke Share Save Genome-wide screening identifies Polycomb repressive complex 1.3 as an essential regulator of human naive pluripotent cell reprogrammingCollier, Amanda J.; Bendall, Adam; Fabian, Charlene; Malcolm, Andrew A.; Tilgner, Katarzyna; Semprich, Claudia, I; Wojdyla, Katarzyna; Nisi, Paola Serena; Kishore, Kamal; Franklin, Valar Nila Roamio; Mirshekar-Syahkal, Bahar; D'Santos, Clive; Plath, Kathrin; Yusa, Kosuke; Rugg-Gunn, Peter J. Share Save Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chainHasegawa, Kana; Ikeda, Shunya; Yaga, Moto; Watanabe, Kouki; Urakawa, Rika; Iehara, Akie; Iwai, Mai; Hashiguchi, Seishin; Morimoto, Soyoko; Fujiki, Fumihiro; Nakajima, Hiroko; Nakata, Jun; Nishida, Sumiyuki; Tsuboi, Akihiro; Oka, Yoshihiro; Yoshihara, Satoshi; Manabe, Masahiro; Ichihara, Hiroyoshi; Mugitani, Atsuko; Aoyama, Yasutaka; Nakao, Takafumi; Hirose, Asao; Hino, Masayuki; Ueda, Shiho; Takenaka, Katsuto; Masuko, Takashi; Akashi, Koichi; Maruno, Takahiro; Uchiyama, Susumu; Takamatsu, Shinji; Wada, Naoki; Morii, Eiichi; Nagamori, Shushi; Motooka, Daisuke; Kanai, Yoshikatsu; Oji, Yusuke; Nakagawa, Tomoyoshi; Kijima, Noriyuki; Kishima, Haruhiko; Ikeda, Atsuyo; Ogino, Takayuki; Shintani, Yasushi; Kubo, Tateki; Mihara, Emiko; Yusa, Kosuke; Sugiyama, Haruo; Takagi, Junichi; Miyoshi, Eiji; Kumanogoh, Atsushi; Hosen, Naoki Share Save The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11Lafage-Pochitaloff, Marina; Gerby, Bastien; Baccini, Veronique; Largeaud, Laetitia; Fregona, Vincent; Prade, Nais; Juvin, Pierre-Yves; Jamrog, Laura; Bories, Pierre; Hebrard, Sylvie; Lagarde, Stephanie; Mansat-De Mas, Veronique; Dovey, Oliver M.; Yusa, Kosuke; Vassiliou, George S.; Jansen, Joop H.; Tekath, Tobias; Rombaut, David; Ameye, Genevieve; Barin, Carole; Bidet, Audrey; Boudjarane, John; Collonge-Rame, Marie-Agnes; Gervais, Carine; Ittel, Antoine; Lefebvre, Christine; Luquet, Isabelle; Michaux, Lucienne; Nadal, Nathalie; Poirel, Helene A.; Radford-Weiss, Isabelle; Ribourtout, Benedicte; Richebourg, Steven; Struski, Stephanie; Terre, Christine; Tigaud, Isabelle; Penther, Dominique; Eclache, Virginie; Fontenay, Michaela; Broccardo, Cyril; Delabesse, Eric Share Save Minimal genome-wide human CRISPR-Cas9 libraryGoncalves, Emanuel; Thomas, Mark; Behan, Fiona M.; Picco, Gabriele; Pacini, Clare; Allen, Felicity; Vinceti, Alessandro; Sharma, Mamta; Jackson, David A.; Price, Stacey; Beaver, Charlotte M.; Dovey, Oliver; Parry-Smith, David; Iorio, Francesco; Parts, Leopold; Yusa, Kosuke; Garnett, Mathew J. Share Save KAT7 is a genetic vulnerability of acute myeloid leukemias driven byMLLrearrangementsAu, Yan Zi; Gu, Muxin; De Braekeleer, Etienne; Gozdecka, Malgorzata; Aspris, Demetrios; Tarumoto, Yusuke; Cooper, Jonathan; Yu, Jason; Ong, Swee Hoe; Chen, Xi; Tzelepis, Konstantinos; Huntly, Brian J. P.; Vassiliou, George; Yusa, Kosuke Share Save 
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