Todd R. Golub - Publications, H-index & Citations

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Todd R. Golub

Broad Institute of MIT and Harvard

176H-index

749Paper Count

26.7WCitation Count

Published Papers 231

Publication Date

Author Correction: Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factors

Nature Communications

IF15.7

2026-05-29

OAAI

Vignesh Shanmugam; Neriman Tokcan; Daniel Chafamo; Sean Sullivan; Mehdi Borji; Haley Martin; Gail Newton; Naeem Nadaf; Saoirse Hanbury; Irving Barrera; Dylan Cable; Jackson Weir; Orr Ashenberg; Geraldine Pinkus; Scott Rodig; Caroline Uhler; Evan Macosko; Margaret Shipp; Abner Louissaint; Fei Chen; Todd R. Golub

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TUMOR MICROENVIRONMENTAL NRG1 DRIVES RESISTANCE TO PI3K/AKT PATHWAY INHIBITION IN PROSTATE CANCER

Journal of Urology

IF6.8

2026-05-01

PREAI

Shee, Kevin; Xue, Lingru; Subramanyam, Vishvak; Golub, Todd R.; Miller, Todd W.; Carroll, Peter R.; Straussman, Ravid; Nguyen, Hao G.

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Sialylated CD43 forms a glyco-immune barrier that restrains antileukemic immunity

Science

IF45.8

2026-04-09

PREAI

Jooho Chung; Mounica Vallurupalli; Sarah Noel; Gail Schor; Sofia Mrowka; Ilario Scapozza; Zelalem Demere; Sachin V. Kammula; Margaret Hu; Sarah Y. Kim; YuhJong Liu; Celeste Nobrega; Jonathan J. Perera; Ewa Wrona; Collins K. Cheruiyot; Yunkang Lin; David W. Wu; Maria Saberi; Aidan Cruickshank; Elliot C. Woods; Cun Lan Chuong; Filippo Birocchi; Ashwin V. Kammula; Omar I. Avila; Nelson Knudsen; Mustafa Kocak; John G. Doench; Dean Procter; Lindsey Thornton; Andrew M. Brunner; Eric Winer; Daniel J. DeAngelo; Jacqueline S. Garcia; Richard M. Stone; Russell W. Jenkins; Marcela V. Maus; Timothy A. Graubert; Kathleen B. Yates; Todd R. Golub; Robert T. Manguso

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Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factors

Nature Communications

IF15.7

2025-12-20

OAAI

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BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models

NATURE CANCER

IF28.5

2024-08-23

OAAI

Rauh, Ulrike; Wei, Guo; Serrano-Wu, Michael; Kosmidis, Georgios; Kaulfuss, Stefan; Siegel, Franziska; Thede, Kai; Mcfarland, James; Lemke, Christopher T.; Werbeck, Nicolas; Nowak-Reppel, Katrin; Pilari, Sabine; Menz, Stephan; Ocker, Matthias; Zhang, Weiqun; Davis, Kyle; Poncet-Montange, Guillaume; Roth, Jennifer; Daniels, Douglas; Kaushik, Virendar K.; Hubbard, Brian; Ziegelbauer, Karl; Golub, Todd R.

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Editor's Note: Androgen-Induced Differentiation and Tumorigenicity of Human Prostate Epithelial Cells

CANCER RESEARCH

IF16.6

2024-08-01

OAAI

Berger, Raanan; Febbo, Phillip G.; Majumder, Pradip K.; Zhao, Jean J.; Mukherjee, Shayan; Signoretti, Sabina; Campbell, K. Thirza; Sellers, William R.; Roberts, Thomas M.; Loda, Massimo; Golub, Todd R.; Hahn, William C.

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Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

MOLECULAR CELL

IF16.6

2024-01-01

OAAI

Hofman, Damon A.; Ruiz-Orera, Jorge; Yannuzzi, Ian; Murugesan, Rakesh; Brown, Adam; Clauser, Karl R.; Condurat, Alexandra L.; van Dinter, Jip T.; Engels, Sem A. G.; Goodale, Amy; van der Lugt, Jasper; Abid, Tanaz; Wang, Li; Zhou, Kevin N.; Vogelzang, Jayne; Ligon, Keith L.; Phoenix, Timothy N.; Roth, Jennifer A.; Root, David E.; Hubner, Norbert; Golub, Todd R.; Bandopadhayay, Pratiti; van Heesch, Sebastiaan; Prensner, John R.

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Rapidly cleared MCL1 inhibitor TTX-810 showing robust efficacy in preclinical tumor models with no effects on cardiomyocytes in vitro and in vivo

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-01

PREAI

Rauh, Ulrike; Kaushik, Virendar; Pilari, Sabine; Kosmidis, Georgios; Serrano-Wu, Michael; Wei, Guo; Zhang, Weiqun; Kaulfuss, Stefan; Thede, Kai; Poncet-Montange, Guillaume; Daniels, Douglas; Lemke, Christopher T.; Hubbard, Brian; Golub, Todd R.

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Circulating tumor DNA association with residual cancer burden after neoadjuvant chemotherapy in triple-negative breast cancer in TBCRC 030

ANNALS OF ONCOLOGY

IF65.4

2023-10-01

OAAI

Parsons, H. A.; Blewett, T.; Chu, X.; Sridhar, S.; Santos, K.; Xiong, K.; Abramson, V. G.; Patel, A.; Cheng, J.; Brufsky, A.; Rhoades, J.; Force, J.; Liu, R.; Traina, T. A.; Carey, L. A.; Rimawi, M. F.; Miller, K. D.; Stearns, V.; Specht, J.; Falkson, C.; Burstein, H. J.; Wolff, A. C.; Winer, E. P.; Tayob, N.; Krop, I. E.; Markrigiorgos, G. M.; Golub, T. R.; Mayer, E. L.; Adalsteinsson, V. A.

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FDX1 regulates cellular protein lipoylation through direct binding to LIAS

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-09-01

OAAI

Dreishpoon, Margaret B.; Bick, Nolan R.; Petrova, Boryana; Warui, Douglas M.; Cameron, Alison; Booker, Squire J.; Kanarek, Naama; Golub, Todd R.; Tsvetkov, Peter

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Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal

GENOME BIOLOGY

IF9.4

2023-08-23

OAAI

Krill-Burger, J. Michael; Dempster, Joshua M.; Borah, Ashir A.; Paolella, Brenton R.; Root, David E.; Golub, Todd R.; Boehm, Jesse S.; Hahn, William C.; McFarland, James M.; Vazquez, Francisca; Tsherniak, Aviad

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BAF COMPLEX PERTURBATION AS A NOVEL THERAPEUTIC OPPORTUNITY IN H3K27M PEDIATRIC GLIOMA

NEURO-ONCOLOGY

IF13.4

2023-06-12

OAAI

Panditharatna, Eshini; Marques, Joana G.; Wang, Tingjian; Trissal, Maria; Liu, Ilon; Jiang, Li; Beck, Alexander; Groves, Andrew; Dharia, Neekesh; Hoffman, Samantha; Kugener, Guillaume; Shaw, McKenzie; Hack, Olivia; Dempster, Joshua; Lareau, Caleb; Quezada, Michael; Stanton, Ann-Catherine; Wyatt, Meghan; Kalani, Zohra; Goodale, Amy; Vazquez, Francisca; Piccioni, Federica; Doench, John; Root, David; Anastas, Jamie; Jones, Kristen; Conway, Amy; Stopka, Sylwia; Regan, Michael; Liang, Yu; Seo, Hyuk-Soo; Song, Kijun; Bashyal, Puspalata; Mathewson, Nathan; Dhe-Paganon, Sirano; Suva, Mario L.; Carcaboso, Angel M.; Lavarino, Cinzia; Mora, Jaume; Nguyen, Quang-De; Ligon, Keith L.; Shi, Yang; Agnihotri, Sameer; Agar, Nathalie Y. R.; Stegmaier, Kimberly; Stiles, Charles D.; Monje, Michelle; Golub, Todd R.; Qi, Jun; Filbin, Mariella G.

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Single duplex DNA sequencing with CODEC detects mutations with high sensitivity

NATURE GENETICS

IF31.8

2023-04-27

OAAI

Bae, Jin H. H.; Liu, Ruolin; Roberts, Eugenia; Nguyen, Erica; Tabrizi, Shervin; Rhoades, Justin; Blewett, Timothy; Xiong, Kan; Gydush, Gregory; Shea, Douglas; An, Zhenyi; Patel, Sahil; Cheng, Ju; Sridhar, Sainetra; Liu, Mei Hong; Lassen, Emilie; Skytte, Anne-Bine; Gronska-Peski, Marta; Shoag, Jonathan E. E.; Evrony, Gilad D. D.; Parsons, Heather A. A.; Mayer, Erica L. L.; Makrigiorgos, G. Mike; Golub, Todd R. R.; Adalsteinsson, Viktor A. A.

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A DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Tabrizi, Shervin; Martin-Alonso, Carmen; Xiong, Kan; Blewett, Timothy; Sridhar, Sainetra; An, Zhenyi; Patel, Sahil; Rodriguez-Aponte, Sergio; Naranjo, Christopher; Shea, Douglas; Golub, Todd; Bhatia, Sangeeta N.; Adalsteinsson, Viktor A.; Love, J. Christopher

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ANJ810 is a highly selective novel MCL1 inhibitor with optimized in vivo clearance showing robust efficacy in preclinical solid and hematological tumor models

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Rauh, Ulrike; Wei, Guo; Serrano-Wu, Michael; Kosmidis, Georgios; Kaulfuss, Stefan; Siegel, Franziska; Thede, Kai; McFarland, James; Lemke, Christopher; Werbeck, Nicolas; Nowak-Reppel, Katrin; Pillari, Sabine; Menz, Stephan; Ocker, Matthias; Hubbard, Brian; Kaushik, Virendar; Ziegelbauer, Karl; Golub, Todd

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The immuno suppress ant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

419

OAAI

Peng, T; Golub, TR; Sabatini, DM

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C-Myc is a critical target for C/EBPα in granulopoiesis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

256

OAAI

Johansen, LM; Iwama, A; Lodie, TA; Sasaki, K; Felsher, DW; Golub, TR; Tenen, DG

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Respiratory failure due to differentiation arrest and expansion of alveolar cells following lung-specific loss of the transcription factor C/EBPα in mice

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Bassères, DS; Levantini, E; Ji, HB; Monti, S; Elf, S; Dayaram, T; Fenyus, M; Kocher, O; Golub, T; Wong, KK; Halmos, B; Tenen, DG

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Gamma interferon triggers interaction between ICSBP (IRF-8) and TEL, recruiting the histone deacetylase HDAC3 to the interferon-responsive element

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Kuwata, T; Gongora, C; Kanno, Y; Sakaguchi, K; Tamura, T; Kanno, T; Basrur, V; Martinez, R; Appella, E; Golub, T; Ozato, K

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MicroRNA-1 Negatively Regulates Expression of the Hypertrophy-Associated Calmodulin and Mef2a Genes

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

393

OAAI

Ikeda, Sadakatsu; He, Aibin; Kong, Sek Won; Lu, Jun; Bejar, Rafael; Bodyak, Natalya; Lee, Kyu-Ho; Ma, Qing; Kang, Peter M.; Golub, Todd R.; Pu, William T.

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Research Directions