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C

Chang C. Liu

University of California Irvine

31H-index
92Paper Count
5.0KCitation Count
Published Papers 43
Publication Date
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Protein engineering: status report
errProtein Engineering, Design and Selection
IF0
err2026-07-17
err0
errOAAI
errHui-wang Ai; Frances H Arnold; Doug Barrick; Hagan Bayley; Alfie-Louise R Brownless; Robert E Campbell; Roger Castells-Graells; Pimchai Chaiyen; Roberto A Chica; Lauren O Chisholm; Daniel Christ; Guo-Chao Chu; Michael Chungyoun; Vincent G H Eijsink; Michael B Elowitz; Douglas J Fansher; Rudi Fasan; Gabriel Foley; Michelle S Frei; Andreas Gagsteiger; Ruiyan Gao; Elizabeth M J Gillam; Jeffrey J Gray; Luis F Guerra; Birte Höcker; Zhiyang Jin; Shina Caroline Lynn Kamerlin; Nobuyasu Koga; Roland E Kontermann; Brian Kuhlman; Olivia A Langlois; Dongyang Li; Roberto D Lins; Chang C Liu; Lei Liu; Diego López Barreiro; Peilong Lu; Sohum Mehta; Ikumi Miyazaki; Manuel M Müller; Serge Muyldermans; Naoto Nemoto; Jeff Nivala; James K Nuñez; Izaiah J Ornelas; Joelle N Pelletier; Andreas Plückthun; Owen T Porth; Kridsadakorn Prakinee; Yujia Qing; Julia C Reisenbauer; Sandy Schmidt; Oliver Seifert; Mikhail G Shapiro; Rachna Sharma; Nilmani Singh; Benjamin J Smith; Jamie B Spangler; Rie Tatsumi-Koga; Takuya Terai; Henrik Terholsen; Mattias Tolhurst; Katherine W Tripp; Vanessa Tanja Trossmann; Chandra L Tucker; Onur Turak; James A Van Deventer; Anikó Várnai; Isabelle F T Viana; Amy M Weeks; K Dane Wittrup; Kingsley L-J Wong; Chenggang Xi; Todd O Yeates; Andy Hsien-Wei Yeh; Jin Zhang; Tiger S Zhang; Huimin Zhao; Fang Zheng; Jingyi Zhu; Sacha Zinn
errShare
errSave
Continuous Hypermutation and Evolution of Noncanonical Amino Acid Synthases
errACS Synthetic Biology
IF3.9
err2026-06-25
err0
PREAI
errYuichi Furuhata; Gordon Rix; Patrick J. Almhjell; Chang C. Liu
errShare
errSave
Continuous Hypermutation and Evolution of Luciferase Variants
errACS Chemical Biology
IF3.8
err2025-12-15
err0
PREAI
errTanya Hadjian; Ria A. Deshpande; Zachary R. Torrey; Amelia W. Hammond; Rosana S. Molina; Kevin Ng; Chang C. Liu; Jennifer A. Prescher
errShare
errSave
Atomically accurate de novo design of antibodies with RFdiffusion
errNature
IF48.5
err2025-11-05
err0
errOAAI
errNathaniel R. Bennett; Joseph L. Watson; Robert J. Ragotte; Andrew J. Borst; DéJenaé L. See; Connor Weidle; Riti Biswas; Yutong Yu; Ellen L. Shrock; Russell Ault; Philip J. Y. Leung; Buwei Huang; Inna Goreshnik; John Tam; Kenneth D. Carr; Benedikt Singer; Cameron Criswell; Basile I. M. Wicky; Dionne Vafeados; Mariana Garcia Sanchez; Ho Min Kim; Susana Vázquez Torres; Sidney Chan; Shirley M. Sun; Timothy T. Spear; Yi Sun; Keelan O’Reilly; John M. Maris; Nikolaos G. Sgourakis; Roman A. Melnyk; Chang C. Liu; David Baker
errShare
errSave
The role of plasmid copy number and mutation rate in evolutionary outcomes
errNature Ecology & Evolution
IF14.5
err2025-07-14
err0
PREAI
errAlexander ‘Olek’ Pisera; Chang C. Liu
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errSave
Ultra-efficient Integration of Gene Libraries onto Yeast Cytosolic Plasmids
errACS SYNTHETIC BIOLOGY
IF3.9
err2025-03-01
err0
errOAAI
errPisera, Alexander Olek; Yu, Yutong; Williams, Rory L.; Liu, Chang C.
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errSave
Enterococcus and Eggerthella species are enriched in the gut microbiomes of COVID-19 cases in Uganda
errGUT PATHOGENS
IF4
err2025-02-04
err0
errOAAI
errAgudelo, Carolina; Kateete, David Patrick; Nasinghe, Emmanuel; Kamulegeya, Rogers; Lubega, Christopher; Mbabazi, Monica; Baker, Noah; Lin, Kathryn Y.; Liu, Chang C.; Kasambula, Arthur Shem; Kigozi, Edgar; Komakech, Kevin; Mukisa, John; Mulumba, Kassim; Mwachan, Patricia; Nakalanda, Brenda Sharon; Nalubega, Gloria Patricia; Nsubuga, Julius; Sitenda, Diana; Ssenfuka, Henry; Cirolia, Giana T.; Gustafson, Jeshua T.; Wang, Ruohong; Nsubuga, Moses Luutu; Yiga, Fahim; Stanley, Sarah A.; Bagaya, Bernard Ssentalo; Elliott, Alison; Joloba, Moses; Wolf, Ashley R.
errShare
errSave
Open-ended molecular recording of sequential cellular events into DNA
errNATURE CHEMICAL BIOLOGY
IF13.7
err2024-11-14
err0
PREAI
errLoveless, Theresa B.; Carlson, Courtney K.; Helmy, Catalina A. Dentzel; Hu, Vincent J.; Ross, Sara K.; Demelo, Matt C.; Murtaza, Ali; Liang, Guohao; Ficht, Michelle; Singhai, Arushi; Pajoh-Casco, Marcello J.; Liu, Chang C.
errShare
errSave
The Impact of Nanobodies on G Protein-Coupled Receptor Structural Biology and Their Potential as Therapeutic Agents
errMOLECULAR PHARMACOLOGY
IF3
err2024-10-01
err1
PREAI
errSalom, David; Wu, Arum; Liu, Chang C.; Palczewski, Krzysztof
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errSave
A Massively Parallel In Vivo Assay of TdT Mutants Yields Variants with Altered Nucleotide Insertion Biases
errACS SYNTHETIC BIOLOGY
IF3.9
err2024-09-20
err0
PREAI
errCarlson, Courtney K.; Loveless, Theresa B.; Milisavljevic, Marija; Kelly, Patrick I.; Mills, Jeremy H.; Tyo, Keith E. J.; Liu, Chang C.
errShare
errSave
Engineering the Activity of a Template-Independent DNA Polymerase
errACS SYNTHETIC BIOLOGY
IF3.9
err2024-07-31
err2
PREAI
errMilisavljevic, Marija; Rodriguez, Teresa Rojas; Carlson, Courtney K.; Liu, Chang C.; Tyo, Keith E. J.
errShare
errSave
Rapidly Inducible Yeast Surface Display for Antibody Evolution with OrthoRep
errACS SYNTHETIC BIOLOGY
IF3.9
err2024-07-25
err2
errOAAI
errPaulk, Alexandra M.; Williams, Rory L.; Liu, Chang C.
errShare
errSave
Protein Engineering and High-Throughput Screening by Yeast Surface Display: Survey of Current Methods
errSMALL SCIENCE
IF8.3
err2023-11-08
err2
errOAAI
errLopez-Morales, Joanan; Vanella, Rosario; Appelt, Elizabeth A.; Whillock, Sarah; Paulk, Alexandra M.; Shusta, Eric V.; Hackel, Benjamin J.; Liu, Chang C.; Nash, Michael A.
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errSave
Discovery of VH domains that allosterically inhibit ENPP1
errNATURE CHEMICAL BIOLOGY
IF13.7
err2023-07-03
err10
errOAAI
errSolomon, Paige E.; Bracken, Colton J.; Carozza, Jacqueline A.; Wang, Haoqing; Young, Elizabeth P.; Wellner, Alon; Liu, Chang C.; Sweet-Cordero, E. Alejandro; Li, Lingyin; Wells, James A.
errShare
errSave
An in silico method to assess antibody fragment polyreactivity
errNATURE COMMUNICATIONS
IF15.7
err2022-12-07
err15
errOAAI
errHarvey, Edward P.; Shin, Jung-Eun; Skiba, Meredith A.; Nemeth, Genevieve R.; Hurley, Joseph D.; Wellner, Alon; Shaw, Ada Y.; Miranda, Victor G.; Min, Joseph K.; Liu, Chang C.; Marks, Debora S.; Kruse, Andrew C.
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errSave
Using continuous directed evolution to improve enzymes for plant applications
errPLANT PHYSIOLOGY
IF6.9
err2021-10-27
err27
errOAAI
errGarcia-Garcia, Jorge D.; Van Gelder, Kristen; Joshi, Jaya; Bathe, Ulschan; Leong, Bryan J.; Bruner, Steven D.; Liu, Chang C.; Hanson, Andrew D.
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errSave
Systems for in vivo hypermutation: a quest for scale and depth in directed evolution
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2021-10-01
err29
errOAAI
errRix, Gordon; Liu, Chang C.
errShare
errSave
Evolving Small-Molecule Biosensors with Improved Performance and Reprogrammed Ligand Preference Using OrthoRep
errACS SYNTHETIC BIOLOGY
IF3.9
err2021-10-01
err28
errOAAI
errJavanpour, Alex A.; Liu, Chang C.
errShare
errSave
Sense and Sense Ability in a Synthetic Genetic Code
errNEW ENGLAND JOURNAL OF MEDICINE
IF78.5
err2021-09-09
err0
PREAI
errLiu, Chang C.
errShare
errSave
Rapid generation of potent antibodies by autonomous hypermutation in yeast
errNATURE CHEMICAL BIOLOGY
IF13.7
err2021-06-24
err76
errOAAI
errWellner, Alon; McMahon, Conor; Gilman, Morgan S. A.; Clements, Jonathan R.; Clark, Sarah; Nguyen, Kianna M.; Ho, Ming H.; Hu, Vincent J.; Shin, Jung-Eun; Feldman, Jared; Hauser, Blake M.; Caradonna, Timothy M.; Wingler, Laura M.; Schmidt, Aaron G.; Marks, Debora S.; Abraham, Jonathan; Kruse, Andrew C.; Liu, Chang C.
errShare
errSave

Research Directions

The data has not been retrieved yet.
Co-authors
Cooperation Journals
S
Stuart L. Schreiber
H-index: 166 · Papers: 1.3K
P
Peter G. Schultz
H-index: 159 · Papers: 880
F
Frances H. Arnold
H-index: 139 · Papers: 924
J
Jay D. Keasling
H-index: 128 · Papers: 861
K
Krzysztof Palczewski
H-index: 115 · Papers: 737
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