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J

Jakub Tolar

University of Minnesota Medical School

68H-index
541Paper Count
1.7WCitation Count
Published Papers 178
Publication Date
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Mechanistic machine learning for prediction of prime editing outcomes
errNature Biotechnology
IF41.7
err2026-08-12
err0
errOAAI
errAlvin Hsu; Peter J. Chen; Angus H. Li; Colin F. Hemez; Xin D. Gao; Markus Terrey; Charlie Nelson; Vijay Selvam; Ana Cristian; Amber N. McElroy; Benjamin J. Steinbeck; Gandhar K. Mahadeshwar; Smriti Pandey; Zachary Barsdale; Paul Z. Chen; Alexander A. Sousa; Holt A. Sakai; Rachel A. Silverstein; Ilias Morad; Ryan K. Krueger; Max W. Shen; Benjamin P. Kleinstiver; Cathleen M. Lutz; Jakub Tolar; Bruce R. Blazar; Mark J. Osborn; David R. Liu
errShare
errSave
Keratinocyte-Derived HMGB1 Promotes Inflammatory Signaling in Epidermolysis Bullosa
errJournal of Investigative Dermatology
IF5.7
err2026-03-09
err0
PREAI
errKacey Bui; Ya-Chu Chang; Wannasiri Chiraphapphaiboon; Jianfeng Wang; Christen Ebens; Anja-Katrin Bielinsky; Hai Dang Nguyen; Jakub Tolar
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errSave
New gene therapies for dystrophic epidermolysis bullosa: progress, promise and persistent gaps
errBRITISH JOURNAL OF DERMATOLOGY
IF9.6
err2025-08-01
err0
errOAAI
errMcGrath, John A.; Tolar, Jakub
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errSave
Inflammasome-resistant IPSC-derived myeloid-derived suppressor cells ameliorate xenogeneic graft-versus-host disease
errBlood
IF23.1
err2025-07-25
err0
PREAI
errLie Ma; Brent Koehn; Michael Zaiken; Keli L. Hippen; Kyle Smith; Jeremy Allred; Robin Williams; Ke Yao; Jordan Fink; Asim Saha; Benjamin Koop; Nathaniel Payne; Renata Widelak; Angela Panoskaltsis-Mortari; Megan J. Riddle; Jakub Tolar; Cindy Eide; Lily Xia; Alec D. Witty; Amit K. Mehta; Matthew Denholtz; Mehrdad Hefazi; Sophia Hani; Saad S. Kenderian; Jeffrey S. Miller; Jeffrey J. Molldrem; Leslie S. Kean; Bahram Valamehr; Bruce R. Blazar
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errSave
Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase
errSCIENCE
IF45.8
err2025-05-15
err0
PREAI
errWitte, Isaac P.; Lampe, George D.; Eitzinger, Simon; Miller, Shannon M.; Berrios, Kiara N.; McElroy, Amber N.; King, Rebeca T.; Stringham, Olivia G.; Gelsinger, Diego R.; Vo, Phuc Leo H.; Chen, Albert T.; Tolar, Jakub; Osborn, Mark J.
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errSave
Targeting cell-surface VISTA expression on allospecific naïve T cells promotes tolerance
errBLOOD
IF23.1
err2025-02-07
err1
PREAI
errKoehn, Brent H.; Nowak, Elizabeth C.; Skopelja-Gardner, Sladjana; Saha, Asim; Zaiken, Michael C.; Allred, Jeremy; Peng, Yiyung; Davis III, Wilson L.; Le Mercier, Isabelle; Schwertner, Nicholas; Molloy, Michael J.; Rothstein, Jay; Carriere, Catherine; Riddle, Megan J.; Eide, Cindy R.; Tolar, Jakub; Panoskaltsis-Mortari, Angela; Smith, Kyle D.; Hippen, Keli L.; Kim, Tae Kon; Noelle, Randolph J.; Blazar, Bruce R.
errShare
errSave
Twin Prime Editing Mediated Exon Skipping/Reinsertion for Restored Collagen VII Expression in Recessive Dystrophic Epidermolysis Bullosa
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2024-12-01
err2
PREAI
errSteinbeck, Benjamin J.; Gao, Xin D.; Mcelroy, Amber N.; Pandey, Smriti; Doman, Jordan L.; Riddle, Megan J.; Xia, Lily; Chen, Weili; Eide, Cindy R.; Lengert, Andre H.; Han, Sang Won; Blazar, Bruce R.; Wandall, Hans H.; Dabelsteen, Sally; Liu, David R.; Tolar, Jakub; Osborn, Mark J.
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errSave
Long-term survival after unrelated donor marrow transplantation for aplastic anaemia after optimized conditioning regimen: a retrospective multicentre cohort study
errECLINICALMEDICINE
IF10
err2024-10-01
err0
errOAAI
errEapen, Mary; Antin, Joseph H.; Tolar, Jakub; Arai, Sally; Horwitz, Mitchell E.; Kou, Jianqun; Leifer, Eric; McCarty, John M.; Nakamura, Ryotaro; Pulsipher, Michael A.; Rowley, Scott D.; Horowitz, Mary M.; Deeg, H. Joachim
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errSave
Allogeneic Hematopoietic Cell Transplant For Bone Marrow Failure or Myelodysplastic Syndrome in Dyskeratosis Congenita/Telomere Biology Disorders: Single-Center, Single-Arm, Open-Label Trial of Reduced-Intensity Conditioning Without Radiation
errTRANSPLANTATION AND CELLULAR THERAPY
IF4.4
err2024-10-01
err0
PREAI
errDimitrov, Marketa; Merkle, Svatava; Cao, Qing; Tryon, Rebecca K.; Vercellotti, Gregory M.; Holtan, Shernan G.; Kao, Roy L.; Srikanthan, Meera; Terezakis, Stephanie A.; Tolar, Jakub; Ebens, Christen L.
errShare
errSave
Beyond the Surface: A Narrative Review Examining the Systemic Impacts of Recessive Dystrophic Epidermolysis Bullosa
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2024-09-01
err3
PREAI
errPopp, Courtney; Miller, William; Eide, Cindy; Tolar, Jakub; Mcgrath, John A.; Ebens, Christen L.
errShare
errSave
Audacity of gene therapy
errBRITISH JOURNAL OF DERMATOLOGY
IF9.6
err2024-08-20
err0
PREAI
errDimitrov, Marketa; Ebens, Christen L.; Tolar, Jakub
errShare
errSave
Chondroitin sulfate proteoglycan 4 increases invasion of recessive dystrophic epidermolysis bullosa-associated cutaneous squamous cell carcinoma by modifying transforming growth factor-β signalling
errBRITISH JOURNAL OF DERMATOLOGY
IF9.6
err2024-07-17
err1
PREAI
errMacaulay, Allison R. K.; Yang, Jianbo; Price, Matthew A.; Forster, Colleen L.; Riddle, Megan J.; Ebens, Christen L.; Albert, Frank W.; Giubellino, Alessio; McCarthy, James B.; Tolar, Jakub
errShare
errSave
Accelerated Aging and Microsatellite Instability in Recessive Dystrophic Epidermolysis Bullosa-Associated- Associated Cutaneous Squamous Cell Carcinoma
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2024-07-01
err1
errOAAI
errLee, Catherine A. A.; Wu, Siyuan; Chow, Yuen Ting; Kofman, Eric; Williams, Valencia; Riddle, Megan; Eide, Cindy; Ebens, Christen L.; Frank, Markus H.; Tolar, Jakub; Hook, Kristen P.; Aldubayan, Saud H.; Frank, Natasha Y.
errShare
errSave
Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2024-06-10
err20
errOAAI
errPandey, Smriti; Gao, Xin D.; Krasnow, Nicholas A.; McElroy, Amber; Tao, Y. Allen; Duby, Jordyn E.; Steinbeck, Benjamin J.; McCreary, Julia; Pierce, Sarah E.; Tolar, Jakub; Meissner, Torsten B.; Chaikof, Elliot L.; Osborn, Mark J.; Liu, David R.
errShare
errSave
Integrating Porous Silicon Nanoneedles within Medical Devices for Nucleic Acid Nanoinjection
errACS NANO
IF16
err2024-05-10
err4
errOAAI
errWang, Cong; Gu, Chenlei; Popp, Courtney; Vashisth, Priya; Mustfa, Salman Ahmad; Martella, Davide Alessandro; Spiteri, Chantelle; Mclennan, Samuel; Sun, Ningjia; Riddle, Megan; Eide, Cindy R.; Parsons, Maddy; Tolar, Jakub; Mcgrath, John A.; Chiappini, Ciro
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errSave
ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa (vol 25, pg 782, 2023)
errCYTOTHERAPY
IF3.2
err2023-09-01
err1
errOAAI
errDieter, Kathrin; Niebergall-Roth, Elke; Daniele, Cristina; Fluhr, Silvia; Frank, Natasha Y.; Ganss, Christoph; Kiritsi, Dimitra; McGrath, John A.; Tolar, Jakub; Frank, Markus H.; Kluth, Mark A.
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errSave
ABCB5+mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa
errCYTOTHERAPY
IF3.2
err2023-07-01
err10
errOAAI
errDieter, Kathrin; Niebergall-Roth, Elke; Daniele, Cristina; Fluhr, Silvia; Frank, Natasha Y.; Ganss, Christoph; Kiritsi, Dimitra; McGrath, John A.; Tolar, Jakub; Frank, Markus H.; Kluth, Mark A.
errShare
errSave
Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity
errNATURE BIOTECHNOLOGY
IF41.7
err2022-11-10
err100
errOAAI
errNeugebauer, Monica E.; Hsu, Alvin; Arbab, Mandana; Krasnow, Nicholas A.; McElroy, Amber N.; Pandey, Smriti; Doman, Jordan L.; Huang, Tony P.; Raguram, Aditya; Banskota, Samagya; Newby, Gregory A.; Tolar, Jakub; Osborn, Mark J.; Liu, David R.
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errSave
Interrogation of RDEB Epidermal Allografts after BMT Reveals Coexpression of Collagen VII and Keratin 15 with Proinflammatory Immune Cells and Fibroblasts
errJOURNAL OF INVESTIGATIVE DERMATOLOGY
IF5.7
err2022-09-01
err4
errOAAI
errRiedl, Julia A.; Riddle, Megan; Xia, Lily; Eide, Cindy; Boull, Christina; Ebens, Christen L.; Tolar, Jakub
errShare
errSave
Retention of epigenetic and transcriptional memory among reprogrammed T cells (T-iPSCs) imparts selective advantage for T cell re-differentiation
errJOURNAL OF IMMUNOLOGY
IF3.4
err2022-05-01
err0
PREAI
errWilliams, Robin L.; Morrow, Alyssa; Allred, Jeremy; Tolar, Jakub; Haining, W. Nicholas; Yosef, Nir; Blazar, Bruce R.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
I
Irving L. Weissman
H-index: 215 · Papers: 1.3K
C
Carl H. June
H-index: 177 · Papers: 1.4K
G
Gordon J. Freeman
H-index: 174 · Papers: 1.1K
B
Bruce R. Blazar
H-index: 148 · Papers: 1.5K
D
Darwin J. Prockop
H-index: 139 · Papers: 820
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