Not logged inTP53 mutation drives unique transcriptional and functional vulnerabilities independent of del(17p) in multiple myeloma
Tsallos, Dimitrios; Ikonen, Nemo; Miettinen, Juho J.; Majumder, Muntasir Mamun; Eldfors, Samuli; Vastrik, Imre; Parsons, Alun; Suvela, Minna; Dunphy, Katie; Dowling, Paul; Bazou, Despina; O'Gorman, Peter; Lievonen, Juha; Silvennoinen, Raija; Anttila, Pekka; Heckman, Caroline A. .png)
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SaveEx vivo venetoclax sensitivity testing predicts treatment response in acute myeloid leukemiaKuusanmaki, Heikki; Kytola, Sari; Vanttinen, Ida; Ruokoranta, Tanja; Ranta, Amanda; Huuhtanen, Jani; Suvela, Minna; Parsons, Alun; Holopainen, Annasofia; Partanen, Anu; Kuusisto, Milla E. L.; Koskela, Sirpa; Raty, Riikka; Itala-Remes, Maija; Vastrik, Imre; Dufva, Olli; Siitonen, Sanna; Porkka, Kimmo; Wennerberg, Krister; Heckman, Caroline A.; Ettala, Pia; Pyorala, Marja; Rimpilainen, Johanna; Siitonen, Timo; Kontro, Mika Share Save Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid LeukemiaMalani, Disha; Kumar, Ashwini; Bruck, Oscar; Kontro, Mika; Yadav, Bhagwan; Hellesoy, Monica; Kuusanmaki, Heikki; Dufva, Olli; Kankainen, Matti; Eldfors, Samuli; Potdar, Swapnil; Saarela, Jani; Turunen, Laura; Parsons, Alun; Vastrik, Imre; Kivinen, Katja; Saarela, Janna; Raty, Riikka; Lehto, Minna; Wolf, Maija; Gjertsen, Bjorn Tore; Mustjoki, Satu; Aittokallio, Tero; Wennerberg, Krister; Heckman, Caroline A.; Kallioniemi, Olli; Porkka, Kimmo Share Save Precision systems medicine in acute myeloid leukemia: real-time translation of tailored therapeutic opportunities arising from ex-vivo drug sensitivity testing and molecular profilingMalani, Disha; Kumar, Ashwni; Yadav, Bhagwan; Kontro, Mika; Potdar, Swapnil; Bruck, Oscar; Kytola, Sari; Saarela, Jani; Eldfors, Samuli; Karjalainen, Riikka; Majumder, Muntasir M.; Vastrik, Imre; Ellonen, Pekka; Kankainen, Matti; Suvela, Minna; Knappila, Siv; Parson, Alun; Palva, Aino; Mattila, Pirkko; Kulesskiy, Evgeny; Turunen, Laura; Laamanen, Karoliina; Lehtinen, Elina; Nurmi, Maria; Suomi, Katja; Muruimagi, Astrid; Gjertsen, Bjorn T.; Mustjoki, Satu; Anders, Simon; Wolf, Maija; Aittokallio, Tero; Wennerberg, Krister; Heckman, Caroline; Porkka, Kimmo; Kallioniemi, Olli Share Save Discovery and clinical implementation of individualized therapies in acute myeloid leukemia based on ex vivo drug sensitivity testing and multi-omics profilingMalani, Disha; Kumar, Ashwini; Yadav, Bhagwan; Kontro, Mika; Potdar, Swapnil; Bruck, Oscar; Kytola, Sari; Saarela, Jani; Eldfors, Samuli; Ojamies, Poojitha; Riikka, Karjalainen; Majumder, Muntasir Mamun; Vastrik, Imre; Ellonen, Pekka; Kankainen, Matti; Suvela, Minna; Knappila, Siv; Parson, Alun; Palva, Aino; Mattila, Pirkko; Kulesskiy, Evgeny; Turunen, Laura; Laamanen, Karoliina; Lehtinen, Elina; Mikkonen, Piia; Nurmi, Maria; Timonen, Sanna; Murumagi, Astrid; Gjersten, Bjorn Tore; Mustjoki, Satu; Aittokallio, Tero; Wennerberg, Krister; Anders, Simon; Wolf, Maija; Heckman, Caroline; Porkka, Kimmo; Kallioniemi, Olli Share Save Individualized Systems Medicine Strategy to Tailor Treatments for Patients with Chemorefractory Acute Myeloid LeukemiaPemovska, Tea; Kontro, Mika; Yadav, Bhagwan; Edgren, Henrik; Eldfors, Samuli; Szwajda, Agnieszka; Almusa, Henrikki; Bespalov, Maxim M.; Ellonen, Pekka; Elonen, Erkki; Gjertsen, Bjorn T.; Karjalainen, Riikka; Kulesskiy, Evgeny; Lagstrom, Sonja; Lehto, Anna; Lepisto, Maija; Lundan, Tuija; Majumder, Muntasir Mamun; Marti, Jesus M. Lopez; Mattila, Pirkko; Murumagi, Astrid; Mustjoki, Satu; Palva, Aino; Parsons, Alun; Pirttinen, Tero; Ramet, Maria E.; Suvela, Minna; Turunen, Laura; Vastrik, Imre; Wolf, Maija; Knowles, Jonathan; Aittokallio, Tero; Heckman, Caroline A.; Porkka, Kimmo; Kallioniemi, Olli; Wennerberg, Krister Share Save The BioPAX community standard for pathway data sharing (vol 28, pg 935, 2010)Demir, Emek; Cary, Michael P.; Paley, Suzanne; Fukuda, Ken; Lemer, Christian; Vastrik, Imre; Wu, Guanming; D'Eustachio, Peter; Schaefer, Carl; Luciano, Joanne; Schacherer, Frank; Martinez-Flores, Irma; Hu, Zhenjun; Jimenez-Jacinto, Veronica; Joshi-Tope, Geeta; Kandasamy, Kumaran; Lopez-Fuentes, Alejandra C.; Mi, Huaiyu; Pichler, Elgar; Rodchenkov, Igor; Splendiani, Andrea; Tkachev, Sasha; Zucker, Jeremy; Gopinath, Gopal; Rajasimha, Harsha; Ramakrishnan, Ranjani; Shah, Imran; Syed, Mustafa; Anwar, Nadia; Babur, Oezguen; Blinov, Michael; Brauner, Erik; Corwin, Dan; Donaldson, Sylva; Gibbons, Frank; Goldberg, Robert; Hornbeck, Peter; Luna, Augustin; Murray-Rust, Peter; Neumann, Eric; Ruebenacker, Oliver; Samwald, Matthias; van Iersel, Martijn; Wimalaratne, Sarala; Allen, Keith; Braun, Burk; Whirl-Carrillo, Michelle; Cheung, Kei-Hoi; Dahlquist, Kam; Finney, Andrew; Gillespie, Marc; Glass, Elizabeth; Gong, Li; Haw, Robin; Honig, Michael; Hubaut, Olivier; Kane, David; Krupa, Shiva; Kutmon, Martina; Leonard, Julie; Marks, Debbie; Merberg, David; Petri, Victoria; Pico, Alex; Ravenscroft, Dean; Ren, Liya; Shah, Nigam; Sunshine, Margot; Tang, Rebecca; Whaley, Ryan; Letovksy, Stan; Buetow, Kenneth H.; Rzhetsky, Andrey; Schachter, Vincent; Sobral, Bruno S.; Dogrusoz, Ugur; McWeeney, Shannon; Aladjem, Mirit; Birney, Ewan; Collado-Vides, Julio; Goto, Susumu; Hucka, Michael; Le Novere, Nicolas; Maltsev, Natalia; Pandey, Akhilesh; Thomas, Paul; Wingender, Edgar; Karp, Peter D.; Sander, Chris; Bader, Gary D. Share Save The BioPAX community standard for pathway data sharing (vol 28, pg 935, 2010)Demir, Emek; Cary, Michael P.; Paley, Suzanne; Fukuda, Ken; Lemer, Christian; Vastrik, Imre; Wu, Guanming; D'Eustachio, Peter; Schaefer, Carl; Luciano, Joanne; Schacherer, Frank; Martinez-Flores, Irma; Hu, Zhenjun; Jimenez-Jacinto, Veronica; Joshi-Tope, Geeta; Kandasamy, Kumaran; Lopez-Fuentes, Alejandra C.; Mi, Huaiyu; Pichler, Elgar; Rodchenkov, Igor; Splendiani, Andrea; Tkachev, Sasha; Zucker, Jeremy; Gopinath, Gopal; Rajasimha, Harsha; Ramakrishnan, Ranjani; Shah, Imran; Syed, Mustafa; Anwar, Nadia; Babur, Oezguen; Blinov, Michael; Brauner, Erik; Corwin, Dan; Donaldson, Sylva; Gibbons, Frank; Goldberg, Robert; Hornbeck, Peter; Luna, Augustin; Murray-Rust, Peter; Neumann, Eric; Reubenacker, Oliver; Samwald, Matthias; van Iersel, Martijn; Wimalaratne, Sarala; Allen, Keith; Braun, Burk; Whirl-Carrillo, Michelle; Cheung, Kei-Hoi; Dahlquist, Kam; Finney, Andrew; Gillespie, Marc; Glass, Elizabeth; Gong, Li; Haw, Robin; Honig, Michael; Hubaut, Olivier; Kane, David; Krupa, Shiva; Kutmon, Martina; Leonard, Julie; Marks, Debbie; Merberg, David; Petri, Victoria; Pico, Alex; Ravenscroft, Dean; Ren, Liya; Shah, Nigam; Sunshine, Margot; Tang, Rebecca; Whaley, Ryan; Letovksy, Stan; Buetow, Kenneth H.; Rzhetsky, Andrey; Schachter, Vincent; Sobral, Bruno S.; Dogrusoz, Ugur; McWeeney, Shannon; Aladjem, Mirit; Birney, Ewan; Collado-Vides, Julio; Goto, Susumu; Hucka, Michael; Le Novere, Nicolas; Maltsev, Natalia; Pandey, Akhilesh; Thomas, Paul; Wingender, Edgar; Karp, Peter D.; Sander, Chris; Bader, Gary D. Share Save The BioPAX community standard for pathway data sharingDemir, Emek; Cary, Michael P.; Paley, Suzanne; Fukuda, Ken; Lemer, Christian; Vastrik, Imre; Wu, Guanming; D'Eustachio, Peter; Schaefer, Carl; Luciano, Joanne; Schacherer, Frank; Martinez-Flores, Irma; Hu, Zhenjun; Jimenez-Jacinto, Veronica; Joshi-Tope, Geeta; Kandasamy, Kumaran; Lopez-Fuentes, Alejandra C.; Mi, Huaiyu; Pichler, Elgar; Rodchenkov, Igor; Splendiani, Andrea; Tkachev, Sasha; Zucker, Jeremy; Gopinath, Gopal; Rajasimha, Harsha; Ramakrishnan, Ranjani; Shah, Imran; Syed, Mustafa; Anwar, Nadia; Babur, Oezguen; Blinov, Michael; Brauner, Erik; Corwin, Dan; Donaldson, Sylva; Gibbons, Frank; Goldberg, Robert; Hornbeck, Peter; Luna, Augustin; Murray-Rust, Peter; Neumann, Eric; Reubenacker, Oliver; Samwald, Matthias; van Iersel, Martijn; Wimalaratne, Sarala; Allen, Keith; Braun, Burk; Whirl-Carrillo, Michelle; Cheung, Kei-Hoi; Dahlquist, Kam; Finney, Andrew; Gillespie, Marc; Glass, Elizabeth; Gong, Li; Haw, Robin; Honig, Michael; Hubaut, Olivier; Kane, David; Krupa, Shiva; Kutmon, Martina; Leonard, Julie; Marks, Debbie; Merberg, David; Petri, Victoria; Pico, Alex; Ravenscroft, Dean; Ren, Liya; Shah, Nigam; Sunshine, Margot; Tang, Rebecca; Whaley, Ryan; Letovksy, Stan; Buetow, Kenneth H.; Rzhetsky, Andrey; Schachter, Vincent; Sobral, Bruno S.; Dogrusoz, Ugur; McWeeney, Shannon; Aladjem, Mirit; Birney, Ewan; Collado-Vides, Julio; Goto, Susumu; Hucka, Michael; Le Novere, Nicolas; Maltsev, Natalia; Pandey, Akhilesh; Thomas, Paul; Wingender, Edgar; Karp, Peter D.; Sander, Chris; Bader, Gary D. Share Save Reactome knowledgebase of human biological pathways and processesMatthews, Lisa; Gopinath, Gopal; Gillespie, Marc; Caudy, Michael; Croft, David; de Bono, Bernard; Garapati, Phani; Hemish, Jill; Hermjakob, Henning; Jassal, Bijay; Kanapin, Alex; Lewis, Suzanna; Mahajan, Shahana; May, Bruce; Schmidt, Esther; Vastrik, Imre; Wu, Guanming; Birney, Ewan; Stein, Lincoln; D'Eustachio, Peter Share Save Reactome: a knowledge base of biologic pathways and processes (vol 8, pg 39, 2007)Vastrik, Imre; D'Eustachio, Peter; Schmidt, Esther; Gopinath, Gopal; Croft, David; de Bono, Bernard; Gillespie, Marc; Jassal, Bijay; Lewis, Suzanna; Matthews, Lisa; Wu, Guanming; Birney, Ewan; Stein, Lincoln Share Save Arabidopsis reactome: A foundation knowledgebase for plant systems biologyTsesmetzis, Nicolas; Couchman, Matthew; Higgins, Janet; Smith, Alison; Doonan, John H.; Seifert, Georg J.; Schmidt, Esther E.; Vastrik, Imre; Birney, Ewan; Wu, Guanming; D'Eustachio, Peter; Stein, Lincoln D.; Morris, Richard J.; Bevan, Michael W.; Walsh, Sean V. Share Save Reactome: a knowledge base of biologic pathways and processesVastrik, Imre; D'Eustachio, Peter; Schmidt, Esther; Joshi-Tope, Geeta; Gopinath, Gopal; Croft, David; de Bono, Bernard; Gillespie, Marc; Jassal, Bijay; Lewis, Suzanna; Matthews, Lisa; Wu, Guanming; Birney, Ewan; Stein, Lincoln Share Save Share Save Share Save Expression of Mad, an antagonist of Myc oncoprotein function, in differentiating keratinocytes during tumorigenesis of the skinLymboussaki, A; Kaipainen, A; Hatva, E; Vastrik, I; Jeskanen, L; Jalkanen, M; Werner, S; Stenback, F; Alitalo, R Share Save 
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