Not logged in Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard Lin, Yu-Yu; Breuer, Kersten; Weichenhan, Dieter; Lafrenz, Pascal; Sarnataro, Antonella; Wilk, Agata; Chepeleva, Maryna; Mucke, Oliver; Schonung, Maximilian; Petermann, Franziska; Kensche, Philip Reiner; Weiser, Lena; Thommen, Frank; Giacomelli, Gideon; Nordstroem, Karl; Gonzalez-Avalos, Edahi; Merkel, Angelika; Kretzmer, Helene; Fischer, Jonas; Kramer, Stephen; Iskar, Murat; Wolf, Stephan; Buchhalter, Ivo; Esteller, Manel; Lawerenz, Christian; Twardziok, Sven; Zapatka, Marc; Hovestadt, Volker; Schlesner, Matthias; Schulz, Marcel H.; Hoffmann, Steve; Gerhauser, Clarissa; Walter, Jorn; Hartmann, Mark; Lipka, Daniel B.; Assenov, Yassen; Bock, Christoph; Plass, Christoph; Toth, Reka; Lutsik, Pavlo Share Save
Share Save
Share Save
Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF (vol 56, pg 1203, 2024) Iurlaro, Mario; Masoni, Francesca; Flyamer, Ilya M.; Wirbelauer, Christiane; Iskar, Murat; Burger, Lukas; Giorgetti, Luca; Schubeler, Dirk Share Save
Integration of transcriptomics, proteomics and loss-of-function screening reveals WEE1 as a target for combination with dasatinib against proneural glioblastoma Alhalabi, Obada T.; Goettmann, Mona; Gold, Maxwell P.; Schlue, Silja; Hielscher, Thomas; Iskar, Murat; Kessler, Tobias; Hai, Ling; Lokumcu, Tolga; Cousins, Clara C.; Herold-Mende, Christel; Hessling, Bernd; Horschitz, Sandra; Jabali, Ammar; Koch, Philipp; Baumgartner, Ulrich; Day, Bryan W.; Wick, Wolfgang; Sahm, Felix; Krieg, Sandro M.; Fraenkel, Ernest; Phillips, Emma; Goidts, Violaine Share Save
Share Save
Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity Lokumcu, Tolga; Iskar, Murat; Schneider, Martin; Helm, Dominic; Klinke, Glynis; Schlicker, Lisa; Bethke, Frederic; Mu''ller, Gabriele; Richter, Karsten; Poschet, Gernot; Phillips, Emma; Goidts, Violaine Share Save
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53 Isbel, Luke; Iskar, Murat; Durdu, Sevi; Weiss, Joscha; Grand, Ralph S.; Hietter-Pfeiffer, Eric; Kozicka, Zuzanna; Michael, Alicia K.; Burger, Lukas; Thomae, Nicolas H.; Schubeler, Dirk Share Save
Proteogenomics refines the molecular classification of chronic lymphocytic leukemia Herbst, Sophie A.; Vesterlund, Mattias; Helmboldt, Alexander J.; Jafari, Rozbeh; Siavelis, Ioannis; Stahl, Matthias; Schitter, Eva C.; Liebers, Nora; Brinkmann, Berit J.; Czernilofsky, Felix; Roider, Tobias; Bruch, Peter-Martin; Iskar, Murat; Kittai, Adam; Huang, Ying; Lu, Junyan; Richter, Sarah; Mermelekas, Georgios; Umer, Husen Muhammad; Knoll, Mareike; Kolb, Carolin; Lenze, Angela; Cao, Xiaofang; Osterholm, Cecilia; Wahnschaffe, Linus; Herling, Carmen; Scheinost, Sebastian; Ganzinger, Matthias; Mansouri, Larry; Kriegsmann, Katharina; Kriegsmann, Mark; Anders, Simon; Zapatka, Marc; Del Poeta, Giovanni; Zucchetto, Antonella; Bomben, Riccardo; Gattei, Valter; Dreger, Peter; Woyach, Jennifer; Herling, Marco; Muller-Tidow, Carsten; Rosenquist, Richard; Stilgenbauer, Stephan; Zenz, Thorsten; Huber, Wolfgang; Tausch, Eugen; Lehtioe, Janne; Dietrich, Sascha Share Save
A synergistic interaction between HDAC- and PARP inhibitors in childhood tumors with chromothripsis Khalid, Umar; Simovic, Milena; Hammann, Linda A.; Iskar, Murat; Wong, John K. L.; Kumar, Rithu; Jugold, Manfred; Sill, Martin; Bolkestein, Michiel; Kolb, Thorsten; Hergt, Michaela; Devens, Frauke; Ecker, Jonas; Kool, Marcel; Milde, Till; Westermann, Frank; Benner, Axel; Lewis, Joe; Dietrich, Sascha; Pfister, Stefan M.; Lichter, Peter; Zapatka, Marc; Ernst, Aurelie Share Save
Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity Hanna, Bola S.; Llao-Cid, Laura; Iskar, Murat; Roessner, Philipp M.; Klett, Lara C.; Wong, John K. L.; Paul, Yashna; Ioannou, Nikolaos; Ozturk, Selcen; Mack, Norman; Kalter, Verena; Colomer, Dolors; Campo, Elias; Bloehdorn, Johannes; Stilgenbauer, Stephan; Dietrich, Sascha; Schmidt, Manfred; Gabriel, Richard; Rippe, Karsten; Feuerer, Markus; Ramsay, Alan G.; Lichter, Peter; Zapatka, Marc; Seiffert, Martina Share Save
Pilocytic astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response Aichmueller, Christian F.; Iskar, Murat; Jones, David T. W.; Korshunov, Andrey; Radlwimmer, Bernhard; Kool, Marcel; Ernst, Aurelie; Pfister, Stefan M.; Lichter, Peter; Zapatka, Marc Share Save
The landscape of viral associations in human cancers Zapatka, Marc; Borozan, Ivan; Brewer, Daniel S.; Iskar, Murat; Grundhoff, Adam; Alawi, Malik; Desai, Nikita; Sueltmann, Holger; Moch, Holger; Cooper, Colin S.; Eils, Roland; Ferretti, Vincent; Lichter, Peter Share Save
Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations Pfaff, Elke; Aichmueller, Christian; Sill, Martin; Stichel, Damian; Snuderl, Matija; Karajannis, Matthias A.; Schuhmann, Martin U.; Schittenhelm, Jens; Hasselblatt, Martin; Thomas, Christian; Korshunov, Andrey; Rhizova, Marina; Wittmann, Andrea; Kaufhold, Anna; Iskar, Murat; Ketteler, Petra; Lohmann, Dietmar; Orr, Brent A.; Ellison, David W.; von Hoff, Katja; Mynarek, Martin; Rutkowski, Stefan; Sahm, Felix; von Deimling, Andreas; Lichter, Peter; Kool, Marcel; Zapatka, Marc; Pfister, Stefan M.; Jones, David T. W. Share Save
Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration Chun, Hye-Jung E.; Johann, Pascal D.; Milne, Katy; Zapatka, Marc; Buellesbach, Annette; Ishaque, Naveed; Iskar, Murat; Erkek, Serap; Wei, Lisa; Tessier-Cloutier, Basile; Lever, Jake; Titmuss, Emma; Topham, James T.; Bowlby, Reanne; Chuah, Eric; Mungall, Karen L.; Ma, Yussanne; Mungall, Andrew J.; Moore, Richard A.; Taylor, Michael D.; Gerhard, Daniela S.; Jones, Steven J. M.; Korshunov, Andrey; Gessler, Manfred; Kerl, Kornelius; Hasselblatt, Martin; Fruehwald, Michael C.; Perlman, Elizabeth J.; Nelson, Brad H.; Pfister, Stefan M.; Marra, Marco A.; Kool, Marcel Share Save
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks Mallm, Jan-Philipp; Iskar, Murat; Ishaque, Naveed; Klett, Lara C.; Kugler, Sabrina J.; Muino, Jose M.; Teif, Vladimir B.; Poos, Alexandra M.; Grossmann, Sebastian; Erdel, Fabian; Tavernari, Daniele; Koser, Sandra D.; Schumacher, Sabrina; Brors, Benedikt; Koenig, Rainer; Remondini, Daniel; Vingron, Martin; Stilgenbauer, Stephan; Lichter, Peter; Zapatka, Marc; Mertens, Daniel; Rippe, Karsten Share Save
Share Save
DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for diffuse intrinsic pontine gliomas Schramm, Kathrin; Iskar, Murat; Statz, Britta; Jaeger, Natalie; Haag, Daniel; Slabicki, Mikolaj; Pfister, Stefan M.; Zapatka, Marc; Gronych, Jan; Jones, David T. W.; Lichter, Peter Share Save
Tumor-derived exosomes modulate PD-L1 expression in monocytes Haderk, Franziska; Schulz, Ralph; Iskar, Murat; Cid, Laura Llao; Worst, Thomas; Willmund, Karolin V.; Schulz, Angela; Warnken, Uwe; Seiler, Jana; Benner, Axel; Nessling, Michelle; Zenz, Thorsten; Gobel, Maria; Durig, Jan; Diederichs, Sven; Paggetti, Jerome; Moussay, Etienne; Stilgenbauer, Stephan; Zapatka, Marc; Lichter, Peter; Seiffert, Martina Share Save
The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR Scharaw, Sandra; Iskar, Murat; Ori, Alessandro; Boncompain, Gaelle; Laketa, Vibor; Poser, Ina; Lundberg, Emma; Perez, Franck; Beck, Martin; Bork, Peer; Pepperkok, Rainer Share Save
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Not logged in.png){kind=icon}