Joseph J. Loparo - Publications, H-index & Citations

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Joseph J. Loparo

Harvard Medical School

34H-index

120Paper Count

7.1KCitation Count

Published Papers 57

Publication Date

Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly

Cell

IF42.5

2025-12-29

OAAI

Zishuo Yu; Pradeep Sathyanarayana; Cong Liu; Joel M.J. Tan; Pan Yang; Biswajit Das; Side Hu; Xiaoyi Fan; Chenggong Ji; Sandra K. Weller; Mrinal Shekhar; Donald M. Coen; Philip J. Kranzusch; Joseph J. Loparo; Jonathan Abraham

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The hit-and-run of cell wall synthesis: LpoB transiently binds and activates PBP1b through a conserved allosteric switch

Nature Communications

IF15.7

2025-07-21

OAAI

Irina Shlosman; Andrea Vettiger; Thomas G. Bernhardt; Andrew C. Kruse; Joseph J. Loparo

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A bipartite interaction with the processivity clamp potentiates Pol IV- mediated TLS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-02-24

OAAI

Chang, Seungwoo; Laureti, Luisa; Thrall, Elizabeth S.; Kay, Marguerite S.; Philippin, Gaelle; Jergic, Slobodan; Pages, Vincent; Loparo, Joseph J.

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Identification of the main barriers to Ku accumulation in chromatin

CELL REPORTS

IF6.9

2024-08-01

OAAI

Bossaert, Madeleine; Moreno, Andrew T.; Peixoto, Antonio; Pillaire, Marie-Jeanne; Chanut, Pauline; Frit, Philippe; Calsou, Patrick; Loparo, Joseph J.; Britton, Sebastien

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Structural role for DNA Ligase IV in promoting the fidelity of non-homologous end joining

NATURE COMMUNICATIONS

IF15.7

2024-02-10

OAAI

Stinson, Benjamin M.; Carney, Sean M.; Walter, Johannes C.; Loparo, Joseph J.

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Holding it together: DNA end synapsis during non-homologous end joining

DNA REPAIR

IF2.7

2023-10-01

OAAI

Loparo, Joseph J.

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Allosteric activation of cell wall synthesis during bacterial growth

NATURE COMMUNICATIONS

IF15.7

2023-06-10

OAAI

Shlosman, Irina; Fivenson, Elayne M. M.; Gilman, Morgan S. A.; Sisley, Tyler A. A.; Walker, Suzanne; Bernhardt, Thomas G. G.; Kruse, Andrew C. C.; Loparo, Joseph J. J.

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H2A.Z deposition by SWR1C involves multiple ATP-dependent steps

NATURE COMMUNICATIONS

IF15.7

2022-11-17

OAAI

Fan, Jiayi; Moreno, Andrew T.; Baier, Alexander S.; Loparo, Joseph J.; Peterson, Craig L.

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Replication stalling activates SSB for recruitment of DNA damage tolerance factors

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-10-03

OAAI

Thrall, Elizabeth S.; Piatt, Sadie C.; Chang, Seungwoo; Loparo, Joseph J.

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Compartmentalization of the replication fork by single-stranded DNA-binding protein regulates translesion synthesis

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-09-20

OAAI

Chang, Seungwoo; Thrall, Elizabeth S.; Laureti, Luisa; Piatt, Sadie C.; Pages, Vincent; Loparo, Joseph J.

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More than just content: building community in the graduate classroom

NATURE BIOTECHNOLOGY

IF41.7

2021-09-09

OAAI

Venkatesh, Madhvi J.; Elchert, Alexandra R.; Fakoya, Bolutife; Fernandez, Francisco; Kwong, Andrew C.; Liu, Yue J.; Lotfy, Peter; Lowe, David D.; Petty, Christopher A.; Rodriguez-delaRosa, Alejandra; Seguinot, Bryan O.; Shi, Yingxiao; Loparo, Joseph J.

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Repair of DNA Double-Strand Breaks by the Nonhomologous End Joining Pathway

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 90, 2021

IF0

2021-06-20

112

OAAI

Stinson, Benjamin M.; Loparo, Joseph J.

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Real-Time Imaging of Polioviral RNA Translocation across a Membrane

MBIO

IF4.7

2021-02-23

OAAI

Karunatilaka, Krishanthi S.; Filman, David J.; Strauss, Mike; Loparo, Joseph J.; Hogle, James M.

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XLF acts as a flexible connector during non-homologous end joining

ELIFE

IF0

2020-12-08

OAAI

Carney, Sean M.; Moreno, Andrew T.; Piatt, Sadie C.; Cisneros-Aguirre, Metztli; Lopezcolorado, Felicia Wednesday; Stark, Jeremy M.; Loparo, Joseph J.

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Catalytically inactive T7 DNA polymerase imposes a lethal replication roadblock

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-07-01

OAAI

Hernandez, Alfredo J.; Lee, Seung-Joo; Chang, Seungwoo; Lee, Jaehun A.; Loparo, Joseph J.; Richardson, Charles C.

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Experimental Design Chalk Talks, a Formative Assessment Employed in a Graduate Molecular Biology Course, Promotes Active Learning and Growth in the Competencies of Experimental Design and Science Communication

FASEB JOURNAL

IF4.2

2020-04-19

PREAI

Heustis, Ronald; Dutta, Sneha; Foster, Olivia; Gold, Heather; Venkatesh, Madhvi; Loparo, Joseph; Gutlerner, Johanna

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A Mechanism to Minimize Errors during Non-homologous End Joining

MOLECULAR CELL

IF16.6

2020-03-01

OAAI

Stinson, Benjamin M.; Moreno, Andrew T.; Walter, Johannes C.; Loparo, Joseph J.

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Embedding academic and professional skills training with experimental-design chalk talks

NATURE BIOTECHNOLOGY

IF41.7

2019-12-03

PREAI

Heustis, Ronald J.; Venkatesh, Madhvi J.; Gutlerner, Johanna L.; Loparo, Joseph J.

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A gatekeeping function of the replicative polymerase controls pathway choice in the resolution of lesion-stalled replisomes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-12-03

OAAI

Chang, Seungwoo; Naiman, Karel; Thrall, Elizabeth S.; Kath, James E.; Jergic, Slobodan; Dixon, Nicholas E.; Fuchs, Robert P.; Loparo, Joseph J.

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The Gene-Silencing Protein MORC-1 Topologically Entraps DNA and Forms Multimeric Assemblies to Cause DNA Compaction

MOLECULAR CELL

IF16.6

2019-08-01

OAAI

Kim, HyeongJun; Yen, Linda; Wongpalee, Somsakul P.; Kirshner, Jessica A.; Mehta, Nicita; Xue, Yan; Johnston, Jonathan B.; Burlingame, Alma L.; Kim, John K.; Loparo, Joseph J.; Jacobsen, Steve E.

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Research Directions