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MEF2B C-terminal mutations enhance transcriptional activity and stability to drive B cell lymphomagenesis Yu, Chuanjiang; Shen, Qiong; Holmes, Antony B.; Mo, Tongwei; Tosato, Anna; Soni, Rajesh Kumar; Corinaldesi, Clarissa; Koul, Sanjay; Pasqualucci, Laura; Hussein, Shafinaz; Forouhar, Farhad; Dalla-Favera, Riccardo; Basso, Katia Share Save
Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers Stokes, Michael E.; Vasciaveo, Alessandro; Small, Jonnell Candice; Zask, Arie; Reznik, Eduard; Smith, Nailah; Wang, Qian; Daniels, Jacob; Forouhar, Farhad; Rajbhandari, Presha; Califano, Andrea; Stockwell, Brent R. Share Save
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The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma Morgado-Palacin, Lucia; Brown, Jessie A.; Martinez, Thomas F.; Garcia-Pedrero, Juana M.; Forouhar, Farhad; Quinn, S. Aidan; Reglero, Clara; Vaughan, Joan; Heydary, Yasamin Hajy; Donaldson, Cynthia; Rodriguez-Perales, Sandra; Allonca, Eva; Granda-Diaz, Rocio; Fernandez, Agustin F.; Fraga, Mario F.; Kim, Arianna L.; Santos-Juanes, Jorge; Owens, David M.; Rodrigo, Juan P.; Saghatelian, Alan; Ferrando, Adolfo A. Share Save
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Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia Reglero, Clara; Dieck, Chelsea L.; Zask, Arie; Forouhar, Farhad; Laurent, Anouchka P.; Lin, Wen-Hsuan W.; Albero, Robert; Miller, Hannah I.; Ma, Cindy; Gastier-Foster, Julie M.; Loh, Mignon L.; Tong, Liang; Stockwell, Brent R.; Palomero, Teresa; Ferrando, Adolfo A. Share Save
Oligomeric interactions maintain active-site structure in a noncooperative enzyme family Li, Yaohui; Zhang, Rongzhen; Wang, Chi; Forouhar, Farhad; Clarke, Oliver B.; Vorobiev, Sergey; Singh, Shikha; Montelione, Gaetano T.; Szyperski, Thomas; Xu, Yan; Hunt, John F. Share Save
Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19 Liu, Hengrui; Iketani, Sho; Zask, Arie; Khanizeman, Nisha; Bednarova, Eva; Forouhar, Farhad; Fowler, Brandon; Hong, Seo Jung; Mohri, Hiroshi; Nair, Manoj S.; Huang, Yaoxing; Tay, Nicholas E. S.; Lee, Sumin; Karan, Charles; Resnick, Samuel J.; Quinn, Colette; Li, Wenjing; Shion, Henry; Xia, Xin; Daniels, Jacob D.; Bartolo-Cruz, Michelle; Farina, Marcelo; Rajbhandari, Presha; Jurtschenko, Christopher; Lauber, Matthew A.; McDonald, Thomas; Stokes, Michael E.; Hurst, Brett L.; Rovis, Tomislav; Chavez, Alejandro; Ho, David D.; Stockwell, Brent R. Share Save
Characterization of a patient-derived variant of GPX4 for precision therapy Liu, Hengrui; Forouhar, Farhad; Seibt, Tobias; Saneto, Russell; Wigby, Kristen; Friedman, Jennifer; Xia, Xin; Shchepinov, Mikhail S.; Ramesh, Sanath Kumar; Conrad, Marcus; Stockwell, Brent R. Share Save
Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors (vol 12, 2016, 2021) Iketani, Sho; Forouhar, Farhad; Liu, Hengrui; Hong, Seo Jung; Lin, Fang-Yu; Nair, Manoj S.; Zask, Arie; Huang, Yaoxing; Xing, Li; Stockwell, Brent R.; Chavez, Alejandro; Ho, David D. Share Save
Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors Iketani, Sho; Forouhar, Farhad; Liu, Hengrui; Hong, Seo Jung; Lin, Fang-Yu; Nair, Manoj S.; Zask, Arie; Huang, Yaoxing; Xing, Li; Stockwell, Brent R.; Chavez, Alejandro; Ho, David D. Share Save
Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator Wang, Chi; Aleksandrov, Andrei A.; Yang, Zhengrong; Forouhar, Farhad; Proctor, Elizabeth A.; Kota, Pradeep; An, Jianli; Kaplan, Anna; Khazanov, Netaly; Boel, Gregory; Stockwell, Brent R.; Senderowitz, Hanoch; Dokholyan, Nikolay V.; Riordan, John R.; Brouillette, Christie G.; Hunt, John F. Share Save
Expression system for structural and functional studies of human glycosylation enzymes Moremen, Kelley W.; Ramiah, Annapoorani; Stuart, Melissa; Steel, Jason; Meng, Lu; Forouhar, Farhad; Moniz, Heather A.; Gahlay, Gagandeep; Gao, Zhongwei; Chapla, Digantkumar; Wang, Shuo; Yang, Jeong-Yeh; Prabhakar, Pradeep Kumar; Johnson, Roy; dela Rosa, Mitche; Geisler, Christoph; Nairn, Alison V.; Seetharaman, Jayaraman; Wu, Sheng-Cheng; Tong, Liang; Gilbert, Harry J.; LaBaer, Joshua; Jarvis, Donald L. Share Save
Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase Lewis-Ballester, Ariel; Forouhar, Farhad; Kim, Sung-Mi; Lew, Scott; Wang, YongQiang; Karkashon, Shay; Seetharaman, Jayaraman; Batabyal, Dipanwita; Chiang, Bing-Yu; Hussain, Munif; Correia, Maria Almira; Yeh, Syun-Ru; Tong, Liang Share Save
Members of a Novel Kinase Family (DUF1537) Can Recycle Toxic Intermediates into an Essential Metabolite Thiaville, Jennifer J.; Flood, Jake; Yurgel, Svetlana; Prunetti, Laurence; Elbadawi-Sidhu, Mona; Hutinet, Geoffrey; Forouhar, Farhad; Zhang, Xinshuai; Ganesan, Venkateswaran; Reddy, Patrick; Fiehn, Oliver; Gerlt, J. A.; Hunt, John F.; Copley, Shelley D.; de Crecy-Lagard, Valerie Share Save
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