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MaveDB 2024: a curated community database with over seven million variant effects from multiplexed functional assays Rubin, Alan F.; Stone, Jeremy; Bianchi, Aisha Haley; Capodanno, Benjamin J.; Da, Estelle Y.; Dias, Mafalda; Esposito, Daniel; Frazer, Jonathan; Fu, Yunfan; Grindstaff, Sally B.; Harrington, Matthew R.; Li, Iris; Mcewen, Abbye E.; Min, Joseph K.; Moore, Nick; Moscatelli, Olivia G.; Ong, Jesslyn; Polunina, Polina V.; Rollins, Joshua E.; Rollins, Nathan J.; Snyder, Ashley E.; Tam, Amy; Wakefield, Matthew J.; Starita, Lea M.; Bryant, Vanessa L.; Marks, Debora S.; Fowler, Douglas M. Share Save
Preclinical pharmacology of S-1117, a novel engineered Fc-fused IgG cleaving enzyme, for chronic treatment of autoantibody-mediated diseases Sanmarco, Liliana; Pellerin, Alex; Anderson, Jordan; Rollins, Nathan; Newton, Andita; Green, Tobias; Le, Nam; Peckner, Ryan; Mande, Purvi; Xing, Xi; Manasson, Julia; Higginson-Scott, Nathan; Sundy, John; Otipoby, Kevin; Mascanfroni, Ivan Share Save
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The promise of machine learning: using Seismic's IMPACT platform to design IgG cleaving enzymes for chronic treatment of autoimmune diseases Pellerin, Alex; Anderson, Jordan; Rollins, Nathan; Sanmarco, Liliana; Newton, Andita; Le, Nam; Shin, June; Hoel, Chris; Cianci, Michael; Hoyt, Emily; Mojta, Shanell; Hollfelder, Melissa; Cipoletta, Daniela; Peckner, Ryan; Higginson-Scott, Nathan; Otipoby, Kevin; Mascanfroni, Ivan Share Save
High-Content Screening and Computational Prediction Reveal Viral Genes That Suppress the Innate Immune Response Ng, Tai L.; Olson, Erika J.; Yoo, Tae Yeon; Weiss, H. Sloane; Koide, Yukiye; Koch, Peter D.; Rollins, Nathan J.; Mach, Pia; Meisinger, Tobias; Bricken, Trenton; Chang, Timothy Z.; Molloy, Colin; Zurcher, Jerome; Chang, Roger L.; Mitchison, Timothy J.; Glass, John, I; Marks, Debora S.; Way, Jeffrey C.; Silver, Pamela A. Share Save
Natural and Designed Proteins Inspired by Extremotolerant Organisms Can Form Condensates and Attenuate Apoptosis in Human Cells Veling, Mike T.; Nguyen, Dan T.; Thadani, Nicole N.; Oster, Michela E.; Rollins, Nathan J.; Brock, Kelly P.; Bethel, Neville P.; Lim, Samuel; Baker, David; Way, Jeffrey C.; Marks, Debora S.; Chang, Roger L.; Silver, Pamela A. Share Save
PDBe-KB: collaboratively defining the biological context of structural data Varadi, Mihaly; Anyango, Stephen; Armstrong, David; Berrisford, John; Choudhary, Preeti; Deshpande, Mandar; Nadzirin, Nurul; Nair, Sreenath S.; Pravda, Lukas; Tanweer, Ahsan; Al-Lazikani, Bissan; Andreini, Claudia; Barton, Geoffrey J.; Bednar, David; Berka, Karel; Blundell, Tom; Brock, Kelly P.; Maria Carazo, Jose; Damborsky, Jiri; David, Alessia; Dey, Sucharita; Dunbrack, Roland; Fernandez Recio, Juan; Fraternali, Franca; Gibson, Toby; Helmer-Citterich, Manuela; Hoksza, David; Hopf, Thomas; Jakubec, David; Kannan, Natarajan; Krivak, Radoslav; Kumar, Manjeet; Levy, Emmanuel D.; London, Nir; Macias, Jose Ramon; Srivatsan, Madhusudhan M.; Marks, Debora S.; Martens, Lennart; McGowan, Stuart A.; McGreig, Jake E.; Modi, Vivek; Gonzalo Parra, R.; Pepe, Gerardo; Piovesan, Damiano; Prilusky, Jaime; Putignano, Valeria; Radusky, Leandro G.; Ramasamy, Pathmanaban; Rausch, Atilio O.; Reuter, Nathalie; Rodriguez, Luis A.; Rollins, Nathan J.; Rosato, Antonio; Serrano, Luis; Singh, Gulzar; Skoda, Petr; Sorzano, Carlos Oscar S.; Stourac, Jan; Sulkowska, Joanna, I; Svobodova, Radka; Tichshenko, Natalia; Tosatto, Silvio C. E.; Vranken, Wim; Wass, Mark N.; Xue, Dandan; Zaidman, Daniel; Thornton, Janet; Sternberg, Michael; Orengo, Christine; Velankar, Sameer Share Save
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Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact Chiasson, Melissa A.; Rollins, Nathan J.; Stephany, Jason J.; Sitko, Katherine A.; Matreyek, Kenneth A.; Verby, Marta; Sun, Song; Roth, Frederick P.; DeSloover, Daniel; Marks, Debora S.; Rettie, Allan E.; Fowler, Douglas M. Share Save
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