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Tom L. Blundell

University of Cambridge

112H-index
736Paper Count
6.2WCitation Count
Published Papers 245
Publication Date
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Cryo-EM structures of NHEJ assemblies with nucleosomes
errNature Communications
IF15.7
err2025-12-24
err0
errOAAI
errChloe Hall; Philippe Frit; Antonia Kefala-Stavridi; Amandine Pelletier; Steven W. Hardwick; Himani Amin; Matthew K. Bilyard; Taiana Maia De Oliviera; Ammarah Tariq; Sayma Zahid; Dimitri Y. Chirgadze; Shankar Balasubramanian; Katheryn Meek; Virginie Ropars; Jean-Baptiste Charbonnier; Mauro Modesti; Patrick Calsou; Sébastien Britton; Tom L. Blundell; Thomas Schalch; Amanda K. Chaplin
errShare
errSave
Metabolic control of porin permeability influences antibiotic resistance in Escherichia coli
errNature Microbiology
IF19.4
err2025-11-24
err0
errOAAI
errSantiago E. Caño Muñiz; Stephen Trigg; Georgeos Hardo; Anja Hagting; Ieuan E. Evans; Christopher Ruis; Ali F. Alsulami; David Summers; Felicity Crawshay-Williams; Tom L. Blundell; Lucas Boeck; Somenath Bakshi; R. Andres Floto
errShare
errSave
Crystal structure of dihydrodipicolinate synthase from Mycobacterium tuberculosis in complex with pyruvate and insights into allosteric regulation
errInternational Journal of Biological Macromolecules
IF8.5
err2025-09-27
err0
PREAI
errLuis Victor Santana Rosa; Beata Blaszczyk; Tom Blundell; Marcio Vinicius Bertacine Dias
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errSave
Similarity of drug targets to human microbiome metaproteome promotes pharmacological promiscuity
errPHARMACOGENOMICS JOURNAL
IF2.9
err2025-04-17
err0
errOAAI
errBeaudoin, Christopher A.; Norget, Shannon; Omran, Ziad; Hala, Sharif; Daqeeq, Abdullah H.; Burnet, Philip W. J.; Blundell, Tom L.; van Tonder, Andries J.
errShare
errSave
Cell envelope polysaccharide modifications alter the surface properties and interactions of Mycobacterium abscessus with innate immune cells in a morphotype-dependent manner
errMBIO
IF4.7
err2025-03-01
err0
errOAAI
errLian, Elena; Belardinelli, Juan M.; De, Kavita; Pandurangan, Arun Prasad; Angala, Shiva K.; Palcekova, Zuzana; Grzegorzewicz, Anna E.; Bryant, Josephine M.; Blundell, Tom L.; Parkhill, Julian; Floto, R. Andres; Wheat, William H.; Jackson, Mary
errShare
errSave
Structure-based drug design with equivariant diffusion models
errNATURE COMPUTATIONAL SCIENCE
IF18.3
err2024-12-09
err0
errOAAI
errSchneuing, Arne; Harris, Charles; Du, Yuanqi; Didi, Kieran; Jamasb, Arian; Igashov, Ilia; Du, Weitao; Gomes, Carla; Blundell, Tom L.; Lio, Pietro; Welling, Max; Bronstein, Michael; Correia, Bruno
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errSave
Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-08-27
err0
errOAAI
errStockwell, Simon R.; Scott, Duncan E.; Fischer, Gerhard; Guarino, Estrella; Rooney, Timothy P. C.; Feng, Tzu-Shean; Moschetti, Tommaso; Srinivasan, Rajavel; Alza, Esther; Asteian, Alice; Dagostin, Claudio; Alcaide, Anna; Rocaboy, Mathieu; Blaszczyk, Beata; Higueruelo, Alicia; Wang, Xuelu; Rossmann, Maxim; Perrior, Trevor R.; Blundell, Tom L.; Spring, David R.; Mckenzie, Grahame; Abell, Chris; Skidmore, John; Venkitaraman, Ashok R.; Hyvonen, Marko
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errSave
A Fragment-Based Competitive 19F LB-NMR Platform For Hotspot-Directed Ligand Profiling
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-08-12
err0
errOAAI
errMccarthy, William J.; Thomas, Sherine E.; Olaleye, Tayo; Boland, Jennifer A.; Floto, R. Andres; Williams, Glyn; Blundell, Tom L.; Coyne, Anthony G.; Abell, Chris
errShare
errSave
Outcomes of the EMDataResource cryo-EM Ligand Modeling Challenge
errNATURE METHODS
IF32.1
err2024-06-25
err1
errOAAI
errLawson, Catherine L.; Kryshtafovych, Andriy; Pintilie, Grigore D.; Burley, Stephen K.; Cerny, Jiri; Chen, Vincent B.; Emsley, Paul; Gobbi, Alberto; Joachimiak, Andrzej; Noreng, Sigrid; Prisant, Michael G.; Read, Randy J.; Richardson, Jane S.; Rohou, Alexis L.; Schneider, Bohdan; Sellers, Benjamin D.; Shao, Chenghua; Sourial, Elizabeth; Williams, Chris I.; Williams, Christopher J.; Yang, Ying; Abbaraju, Venkat; Afonine, Pavel V.; Baker, Matthew L.; Bond, Paul S.; Blundell, Tom L.; Burnley, Tom; Campbell, Arthur; Cao, Renzhi; Cheng, Jianlin; Chojnowski, Grzegorz; Cowtan, K. D.; DiMaio, Frank; Esmaeeli, Reza; Giri, Nabin; Grubmueller, Helmut; Hoh, Soon Wen; Hou, Jie; Hryc, Corey F.; Hunte, Carola; Igaev, Maxim; Joseph, Agnel P.; Kao, Wei-Chun; Kihara, Daisuke; Kumar, Dilip; Lang, Lijun; Lin, Sean; Subramaniya, Sai R. Maddhuri Venkata; Mittal, Sumit; Mondal, Arup; Moriarty, Nigel W.; Muenks, Andrew; Murshudov, Garib N.; Nicholls, Robert A.; Olek, Mateusz; Palmer, Colin M.; Perez, Alberto; Pohjolainen, Emmi; Pothula, Karunakar R.; Rowley, Christopher N.; Sarkar, Daipayan; Schaefer, Luisa U.; Schlicksup, Christopher J.; Schroeder, Gunnar F.; Shekhar, Mrinal; Si, Dong; Singharoy, Abhishek; Sobolev, Oleg V.; Terashi, Genki; Vaiana, Andrea C.; Vedithi, Sundeep C.; Verburgt, Jacob; Wang, Xiao; Warshamanage, Rangana; Winn, Martyn D.; Weyand, Simone; Yamashita, Keitaro; Zhao, Minglei; Schmid, Michael F.; Berman, Helen M.; Chiu, Wah
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errSave
Machine learning-aided generative molecular design
errNATURE MACHINE INTELLIGENCE
IF23.9
err2024-06-18
err11
PREAI
errDu, Yuanqi; Jamasb, Arian R.; Guo, Jeff; Fu, Tianfan; Harris, Charles; Wang, Yingheng; Duan, Chenru; Lio, Pietro; Schwaller, Philippe; Blundell, Tom L.
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errSave
Lipoarabinomannan modification as a source of phenotypic heterogeneity in host- adapted Mycobacterium abscessus isolates
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-04-17
err2
PREAI
errDe, Kavita; Belardinelli, Juan M.; Pandurangan, Arun Prasad; Ehianeta, Teddy; Lian, Elena; Palcekova, Zuzana; Lam, Ha; Gonzalez-juarrero, Mercedes; Bryant, Josephine M.; Blundell, Tom L.; Parkhill, Julian; Floto, R. Andres; Lowary, Todd L.; Wheat, William H.; Jackson, Mary
errShare
errSave
Computational analyses of drug resistance mutations in katG and emb complexes in Mycobacterium tuberculosis
errPROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
IF2.8
err2024-03-14
err0
errOAAI
errBasrai, Aadam; Blundell, Tom L.; Pandurangan, Arun Prasad
errShare
errSave
Clinically relevant mutations in the PhoR sensor kinase of host-adapted Mycobacterium abscessus isolates impact response to acidic pH and virulence
errMICROBIOLOGY SPECTRUM
IF3.8
err2023-12-12
err7
errOAAI
errBelardinelli, Juan M.; Arora, Divya; Avanzi, Charlotte; Wheat, William H.; Bryant, Josephine M.; Spencer, John S.; Blundell, Tom L.; Parkhill, Julian; Floto, R. Andres; Jackson, Mary
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errSave
Mutational spectra are associated with bacterial niche
errNATURE COMMUNICATIONS
IF15.7
err2023-11-04
err0
errOAAI
errRuis, Christopher; Weimann, Aaron; Tonkin-Hill, Gerry; Pandurangan, Arun Prasad; Matuszewska, Marta; Murray, Gemma G. R.; Levesque, Roger C.; Blundell, Tom L.; Floto, R. Andres; Parkhill, Julian
errShare
errSave
Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-10-23
err0
errOAAI
errKefala Stavridi, Antonia; Gontier, Amandine; Morin, Vincent; Frit, Philippe; Ropars, Virginie; Barboule, Nadia; Racca, Carine; Jonchhe, Sagun; Morten, Michael J.; Andreani, Jessica; Rak, Alexey; Legrand, Pierre; Bourand-Plantefol, Alexa; Hardwick, Steven W.; Chirgadze, Dimitri Y.; Davey, Paul; De Oliveira, Taiana Maia; Rothenberg, Eli; Britton, Sebastien; Calsou, Patrick; Blundell, Tom L.; Varela, Paloma F.; Chaplin, Amanda K.; Charbonnier, Jean-Baptiste
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errSave
Two distinct long-range synaptic complexes promote different aspects of end processing prior to repair of DNA breaks by non-homologous end joining
errMOLECULAR CELL
IF16.6
err2023-03-01
err19
errOAAI
errBuehl, Christopher J.; Goff, Noah J.; Hardwick, Steven W.; Gellert, Martin; Blundell, Tom L.; Yang, Wei; Chaplin, Amanda K.; Meek, Katheryn
errShare
errSave
Human DNA-dependent protein kinase activation mechanism
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2023-01-05
err11
errOAAI
errLiang, Shikang; Blundell, Tom L.
errShare
errSave
Catalytically inactive DNA ligase IV promotes DNA repair in living cells
errNUCLEIC ACIDS RESEARCH
IF13.1
err2022-10-20
err15
errOAAI
errGoff, Noah J.; Breniere, Manon; Buehl, Christopher J.; de Melo, Abinadabe J.; Huskova, Hana; Ochi, Takashi; Blundell, Tom L.; Mao, Weifeng; Yu, Kefei; Modesti, Mauro; Meek, Katheryn
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Editors introduction JBPM volume 174
errPROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
IF4.5
err2022-10-01
err0
PREAI
errBlundell, Tom
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An Overview
errPROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
IF4.5
err2022-09-01
err2
PREAI
errBlundell, Tom L.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
D
D. Gareth Evans
H-index: 182 · Papers: 2.5K
J
Julian Parkhill
H-index: 177 · Papers: 1.1K
S
Stephen P. Jackson
H-index: 136 · Papers: 667
J
Janet M. Thornton
H-index: 135 · Papers: 784
E
Eamonn R. Maher
H-index: 134 · Papers: 850
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