Not logged in Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1 White, Eoghann; Papagno, Laura; Samri, Assia; Sugata, Kenji; Hejblum, Boris; Henry, Amy R.; Rogan, Daniel C.; Darko, Samuel; Recordon-Pinson, Patricia; Dudoit, Yasmine; Llewellyn-Lacey, Sian; Chakrabarti, Lisa A.; Buseyne, Florence; Migueles, Stephen A.; Price, David A.; Andreola, Marie-Aline; Satou, Yorifumi; Thiebaut, Rodolphe; Katlama, Christine; Autran, Brigitte; Douek, Daniel C.; Appay, Victor Share Save
Development of non-smoking lung cancers by indoor carcinogenic aerosols through epigenetic reprogramming of lung stem cells: Bioinformatics and artificial intelligence analysis Anderson, Juan; Delgado, Mariah; Lovett, Malcolm; Saunders, Maya; Lake, Geovannie; Darko, Samuel; Stiffin, Rose M.; Huisso, Ayivi; Sherman, Marilyn; Appleton, Latoya; Mihnea, Amalya; Das, Swarnava; Algahtani, Mohammad M.; Vadapalli, Ravi; Basu, Biswarup; Biswas, Arunima; Neha, Noor; Das, Madhumita; Ruiz, Marco A.; Doke, Mayur; Das, Jayanta K. Share Save
Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates Schramm, Chaim A.; Moon, Damee; Peyton, Lowrey; Lima, Noemia S.; Wake, Christian; Boswell, Kristin L.; Henry, Amy R.; Laboune, Farida; Ambrozak, David; Darko, Samuel W.; Teng, I-Ting; Foulds, Kathryn E.; Carfi, Andrea; Edwards, Darin K.; Kwong, Peter D.; Koup, Richard A.; Seder, Robert A.; Douek, Daniel C. Share Save
Human CCR6+ Th Cells Show Both an Extended Stable Gradient of Th17 Activity and Imprinted Plasticity Singh, Satya P.; Parween, Farhat; Edara, Nithin; Zhang, Hongwei H.; Chen, Jinguo; Otaizo-Carrasquero, Francisco; Cheng, Debby; Oppenheim, Nicole A.; Ransier, Amy; Zhu, Wenjun; Shamsaddini, Amirhossein; Gardina, Paul J.; Darko, Samuel W.; Singh, Tej Pratap; Douek, Daniel C.; Myers, Timothy G.; Farber, Joshua M. Share Save
Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01B malaria vaccine Nielsen, Carolyn M.; Barrett, Jordan R.; Davis, Christine; Fallon, Jonathan K.; Goh, Cyndi; Michell, Ashlin R.; Griffin, Catherine; Kwok, Andrew; Loos, Carolin; Darko, Samuel; Laboune, Farida; Tekman, Mehmet; Diouf, Ababacar; Miura, Kazutoyo; Francica, Joseph R.; Ransier, Amy; Long, Carole A.; Silk, Sarah E.; Payne, Ruth O.; Minassian, Angela M.; Lauffenburger, Douglas A.; Seder, Robert A.; Douek, Daniel C.; Alter, Galit; Draper, Simon J. Share Save
HIV infected CD4+T cell clones are more stable than uninfected clones during long-term antiretroviral therapy Guo, Shuang; Luke, Brian T.; Henry, Amy R.; Darko, Samuel; Brandt, Leah D.; Su, Ling; Sun, David; Wells, Daria; Joseph, Kevin W.; Demirov, Dimiter; Halvas, Elias K.; Douek, Daniel C.; Wu, Xiaolin; Mellors, John W.; Hughes, Stephen H. Share Save
Acquisition of optimal TFH cell function is defined by specific molecular, positional, and TCR dynamic signatures Padhan, Kartika; Moysi, Eirini; Noto, Alessandra; Chassiakos, Alexander; Ghneim, Khader; Perra, Maria Maddalena; Shah, Sanjana; Papaioannou, Vasilis; Fabozzi, Giulia; Ambrozak, David R.; Poultsidi, Antigoni; Ioannou, Maria; Fenwick, Craig; Darko, Samuel; Douek, Daniel C.; Sekaly, Rafick-Pierre; Pantaleo, Giuseppe; Koup, Richard A.; Petrovas, Constantinos Share Save
Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses Mukhamedova, Maryam; Wrapp, Daniel; Shen, Chen-Hsiang; Gilman, Morgan S. A.; Ruckwardt, Tracy J.; Schramm, Chaim A.; Ault, Larissa; Chang, Lauren; Derrien-Colemyn, Alexandrine; Lucas, Sarah A. M.; Ransier, Amy; Darko, Samuel; Phung, Emily; Wang, Lingshu; Zhang, Yi; Rush, Scott A.; Madan, Bharat; Stewart-Jones, Guillaume B. E.; Costner, Pamela J.; Holman, LaSonji A.; Hickman, Somia P.; Berkowitz, Nina M.; Doria-Rose, Nicole A.; Morabito, Kaitlyn M.; DeKosky, Brandon J.; Gaudinski, Martin R.; Chen, Grace L.; Crank, Michelle C.; Misasi, John; Sullivan, Nancy J.; Douek, Daniel C.; Kwong, Peter D.; Graham, Barney S.; McLellan, Jason S.; Mascola, John R. Share Save
Pre-existing Immunity to Japanese Encephalitis Virus Alters CD4 T Cell Responses to Zika Virus Inactivated Vaccine Lima, Noemia S.; Moon, Damee; Darko, Samuel; De La Barrera, Rafael A.; Lin, Leyi; Koren, Michael A.; Jarman, Richard G.; Eckels, Kenneth H.; Thomas, Stephen J.; Michael, Nelson L.; Modjarrad, Kayvon; Douek, Daniel C.; Trautmann, Lydie Share Save
Benchmarking of T cell receptor repertoire profiling methods reveals large systematic biases Barennes, Pierre; Quiniou, Valentin; Shugay, Mikhail; Egorov, Evgeniy S.; Davydov, Alexey N.; Chudakov, Dmitriy M.; Uddin, Imran; Ismail, Mazlina; Oakes, Theres; Chain, Benny; Eugster, Anne; Kashofer, Karl; Rainer, Peter P.; Darko, Samuel; Ransier, Amy; Douek, Daniel C.; Klatzmann, David; Mariotti-Ferrandiz, Encarnita Share Save
SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues Starke, Carly E.; Vinton, Carol L.; Ladell, Kristin; McLaren, James E.; Ortiz, Alexandra M.; Mudd, Joseph C.; Flynn, Jacob K.; Lai, Stephen H.; Wu, Fan; Hirsch, Vanessa M.; Darko, Samuel; Douek, Daniel C.; Price, David A.; Brenchley, Jason M. Share Save
Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells Nguyen, Son; Deleage, Claire; Darko, Samuel; Ransier, Amy; Truong, Duc P.; Agarwal, Divyansh; Japp, Alberto Sada; Wu, Vincent H.; Kuri-Cervantes, Leticia; Abdel-Mohsen, Mohamed; Del Rio Estrada, Perla M.; Ablanedo-Terrazas, Yuria; Gostick, Emma; Hoxie, James A.; Zhang, Nancy R.; Naji, Ali; Reyes-Teran, Gustavo; Estes, Jacob D.; Price, David A.; Douek, Daniel C.; Deeks, Steven G.; Buggert, Marcus; Betts, Michael R. Share Save
Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual Krebs, Shelly J.; Kwon, Young D.; Schramm, Chaim A.; Law, William H.; Donofrio, Gina; Zhou, Kenneth H.; Gift, Syna; Dussupt, Vincent; Georgiev, Ivelin S.; Schatzle, Sebastian; McDaniel, Jonathan R.; Lai, Yen-Ting; Sastry, Mallika; Zhang, Baoshan; Jarosinski, Marissa C.; Ransier, Amy; Chenine, Agnes L.; Asokan, Mangaiarkarasi; Bailer, Robert T.; Bose, Meera; Cagigi, Alberto; Cale, Evan M.; Chuang, Gwo-Yu; Darko, Samuel; Driscoll, Jefferson, I; Druz, Aliaksandr; Gorman, Jason; Laboune, Farida; Louder, Mark K.; McKee, Krisha; Mendez, Letzibeth; Moody, M. Anthony; O'Sullivan, Anne Marie; Owen, Christopher; Peng, Dongjun; Rawi, Reda; Sanders-Buell, Eric; Shen, Chen-Hsiang; Shiakolas, Andrea R.; Stephens, Tyler; Tsybovsky, Yaroslav; Tucker, Courtney; Verardi, Raffaello; Wang, Keyun; Zhou, Jing; Zhou, Tongqing; Georgiou, George; Alam, S. Munir; Haynes, Barton F.; Rolland, Morgane; Matyas, Gary R.; Polonis, Victoria R.; McDermott, Adrian B.; Douek, Daniel C.; Shapiro, Lawrence; Tovanabutra, Sodsai; Michael, Nelson L.; Mascola, John R.; Robb, Merlin L.; Kwong, Peter D.; Doria-Rose, Nicole A. Share Save
Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue Buggert, Marcus; Son Nguyen; de Oca, Gonzalo Salgado-Montes; Bengsch, Bertram; Darko, Samuel; Ransier, Amy; Roberts, Emily R.; del Alcazar, Daniel; Brody, Irene Bukh; Vella, Laura A.; Beura, Lalit; Wijeyesinghe, Sathi; Herati, Ramin S.; Estrada, Perla M. Del Rio; Ablanedo-Terrazas, Yuria; Kuri-Cervantes, Leticia; Japp, Alberto Sada; Manne, Sasikanth; Vartanian, Shant; Huffman, Austin; Sandberg, Johan K.; Gostick, Emma; Nadolski, Gregory; Silvestri, Guido; Canaday, David H.; Price, David A.; Petrovas, Constantinos; Su, Laura F.; Vahedi, Golnaz; Dori, Yoav; Frank, Ian; Itkin, Maxim G.; Wherry, E. John; Deeks, Steven G.; Naji, Ali; Reyes-Teran, Gustavo; Masopust, David; Douek, Daniel C.; Betts, Michael R. Share Save
Characterization of the Neutralizing Antibody Response in a Case of Genetically Linked HIV Superinfection Ssemwanga, Deogratius; Doria-Rose, Nicole A.; Redd, Andrew D.; Shiakolas, Andrea R.; Longosz, Andrew F.; Nsubuga, Rebecca N.; Mayanja, Billy N.; Asiki, Gershim; Seeley, Janet; Kamali, Anatoli; Ransier, Amy; Darko, Samuel; Walker, Michael P.; Bruno, Daniel; Martens, Craig; Douek, Daniel; Porcella, Stephen F.; Quinn, Thomas C.; Mascola, John R.; Kaleebu, Pontiano Share Save
Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state Afik, Shaked; Yates, Kathleen B.; Bi, Kevin; Darko, Samuel; Godec, Jernej; Gerdemann, Ulrike; Swadling, Leo; Douek, Daniel C.; Klenerman, Paul; Barnes, Eleanor J.; Sharpe, Arlene H.; Haining, W. Nicholas; Yosef, Nir Share Save
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System-wide Analysis of the T Cell Response Covacu, Ruxandra; Philip, Hagit; Jaronen, Merja; Almeida, Jorge; Kenison, Jessica E.; Darko, Samuel; Chao, Chun-Cheih; Yaari, Gur; Louzoun, Yoram; Carmel, Liran; Douek, Daniel C.; Efroni, Sol; Quintana, Francisco J. Share Save
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