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H

H. Uri Saragovi

lady davis institute

45H-index
166Paper Count
5.7KCitation Count
Published Papers 65
Publication Date
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p75NTR antagonist THX-B increases mature nerve growth factor secretion by bladder cells through decreased activity of matrix metalloproteinase-9
errMOLECULAR AND CELLULAR ENDOCRINOLOGY
IF3.6
err2025-04-01
err0
PREAI
errHamouda, Aalya; Sirmakesyan, Stephanie; Hajj, Aya; Cammisotto, Philippe G.; Saragovi, H. Uri; Campeau, Lysanne
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Selective inhibitors of the TrkC.T1 receptor reduce retinal inflammation and delay neuronal death in a model of retinitis pigmentosa
errPNAS NEXUS
IF3.8
err2025-02-04
err1
errOAAI
errBrahimi, Fouad; Nassour, Hassan; Galan, Alba; Guruswamy, Revathy; Ortiz, Christina; Nejatie, Ali; Nedev, Hinyu; Trempe, Jean-Francois; Saragovi, H. Uri
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Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses (vol 131, e140752, 2021)
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-05-01
err0
errOAAI
errHuang, Fan; Goncalves, Christophe; Bartish, Margarita; Remy-Sarrazin, Joelle; Issa, Mark E.; Cordeiro, Brendan; Guo, Qianyu; Emond, Audrey; Attias, Mikhael; Yang, William; Plourde, Dany; Su, Jie; Gimeno, Marina Godoy; Zhan, Yao; Galan, Alba; Rzymski, Tomasz; Mazan, Milena; Masiejczyk, Magdalena; Faber, Jacek; Khoury, Elie; Benoit, Alexandre; Gagnon, Natascha; Dankort, David; Journe, Fabrice; Ghanem, Ghanem E.; Krawczyk, Connie M.; Saragovi, H. Uri; Piccirillo, Ciriaco A.; Sonenberg, Nahum; Topisirovic, Ivan; Rudd, Christopher E.; Miller Jr, Wilson H.; del Rincon, Sonia V.
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The cancer glycocode as a family of diagnostic biomarkers, exemplified by tumor-associated gangliosides
errFRONTIERS IN ONCOLOGY
IF3.3
err2023-10-26
err2
errOAAI
errNejatie, Ali; Yee, Samantha S.; Jeter, Anna; Saragovi, Horacio Uri
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errSave
Alpha-2-macroglobulin prevents platelet aggregation induced by brain-derived neurotrophic factor
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2023-09-01
err2
PREAI
errJourdi, Georges; Boukhatem, Imane; Barcelona, Pablo F.; Fleury, Samuel; Welman, Melanie; Saragovi, H. Uri; Pasquali, Samuela; Lordkipanidze, Marie
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errSave
GD2 and GD3 gangliosides as diagnostic biomarkers for all stages and subtypes of epithelial ovarian cancer
errFRONTIERS IN ONCOLOGY
IF3.3
err2023-04-14
err8
errOAAI
errGalan, Alba; Papaluca, Arturo; Nejatie, Ali; Matanes, Emad; Brahimi, Fouad; Tong, Wenyong; Hachim, Ibrahim Yaseen; Yasmeen, Amber; Carmona, Euridice; Klein, Kathleen Oros; Billes, Sonja; Dawod, Ahmed E.; Gawande, Prasad; Jeter, Anna Milik; Mes-Masson, Anne-Marie; Greenwood, Celia M. T.; Gotlieb, Walter H.; Saragovi, H. Uri
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errSave
A Pro-Nerve Growth Factor (proNGF) and NGF Binding Protein, α2-Macroglobulin, Differentially Regulates p75 and TrkA Receptors and Is Relevant to Neurodegeneration Ex Vivo and In Vivo
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err55
errOAAI
errBarcelona, Pablo F.; Saragovi, H. Uri
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errSave
Etiological Roles of p75NTR in a Mouse Model of Wet Age-Related Macular Degeneration
errCELLS
IF5.2
err2023-01-12
err1
errOAAI
errSubirada, Paula Virginia; Tovo, Albana; Vaglienti, Maria Victoria; Pinto, Jose Domingo Luna; Saragovi, Horacio Uri; Sanchez, Maria Cecilia; Anastasia, Agustin; Barcelona, Pablo Federico
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errSave
Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies
errBRAIN
IF11.7
err2021-12-17
err23
errOAAI
errXhima, Kristiana; Markham-Coultes, Kelly; Kofoed, Rikke Hahn; Saragovi, H. Uri; Hynynen, Kullervo; Aubert, Isabelle
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Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
errNATURE CANCER
IF28.5
err2021-11-25
err92
errOAAI
errGarcia-Silva, Susana; Benito-Martin, Alberto; Nogues, Laura; Hernandez-Barranco, Alberto; Mazariegos, Marina S.; Santos, Vanesa; Hergueta-Redondo, Marta; Ximenez-Embun, Pilar; Kataru, Raghu P.; Lopez, Ana Amor; Merino, Cristina; Sanchez-Redondo, Sara; Grana-Castro, Osvaldo; Matei, Irina; Nicolas-Avila, Jose Angel; Torres-Ruiz, Raul; Rodriguez-Perales, Sandra; Martinez, Lola; Perez-Martinez, Manuel; Mata, Gadea; Kalinowska, Iwona; Saltari, Annalisa; Martinez-Gomez, Julia M.; Hogan, Sabrina A.; Saragovi, H. Uri; Ortega, Sagrario; Garcia-Martin, Carmen; Boskovic, Jasminka; Levesque, Mitchell P.; Rutkowski, Piotr; Hidalgo, Andres; Munoz, Javier; Megias, Diego; Mehrara, Babak J.; Lyden, David; Peinado, Hector
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Therapeutic Neuroprotection by an Engineered Neurotrophin that Selectively Activates Tropomyosin Receptor Kinase (Trk) Family Neurotrophin Receptors but Not the p75 Neurotrophin Receptor
errMOLECULAR PHARMACOLOGY
IF3
err2021-11-01
err5
errOAAI
errBrahimi, Fouad; Galan, Alba; Siegel, Sairey; Szobota, Stephanie; Sarunic, Marinko, V; Foster, Alan C.; Saragovi, H. Uri
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errSave
Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2021-04-15
err36
errOAAI
errHuang, Fan; Goncalves, Christophe; Bartish, Margarita; Remy-Sarrazin, Joelle; Issa, Mark E.; Cordeiro, Brendan; Guo, Qianyu; Emond, Audrey; Attias, Mikhael; Yang, William; Plourde, Dany; Su, Jie; Gimeno, Marina Godoy; Zhan, Yao; Galan, Alba; Rzymski, Tomasz; Mazan, Milena; Masiejczyk, Magdalena; Faber, Jacek; Khoury, Elie; Benoit, Alexandre; Gagnon, Natascha; Dankort, David; Journe, Fabrice; Ghanem, Ghanem E.; Krawczyk, Connie M.; Saragovi, H. Uri; Piccirillo, Ciriaco A.; Sonenberg, Nahum; Topisirovic, Ivan; Rudd, Christopher E.; Miller, Wilson H. Jr Jr; del Rincon, Sonia, V
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errSave
Rapid High-Yield Production of Functional SARS-CoV-2 Receptor Binding Domain by Viral and Non-Viral Transient Expression for Pre-Clinical Evaluation
errVACCINES
IF3.4
err2020-11-04
err28
errOAAI
errFarnos, Omar; Venereo-Sanchez, Alina; Xu, Xingge; Chan, Cindy; Dash, Shantoshini; Chaabane, Hanan; Sauvageau, Janelle; Brahimi, Fouad; Saragovi, Uri; Leclerc, Denis; Kamen, Amine A.
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errSave
Aiming for the Sweet Spot: Glyco-Immune Checkpoints and γδ T Cells in Targeted Immunotherapy
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2020-09-29
err20
errOAAI
errBartish, Margarita; del Rincon, Sonia V.; Rudd, Christopher E.; Saragovi, H. Uri
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errSave
Antagonism of proNGF or its receptor p75NTR reverses remodelling and improves bladder function in a mouse model of diabetic voiding dysfunction
errDIABETOLOGIA
IF10.2
err2020-07-22
err20
errOAAI
errMossa, Abubakr H.; Galan, Alba; Cammisotto, Philippe G.; Flores, Monica Velasquez; Shamout, Samer; Barcelona, Pablo; Saragovi, H. Uri; Campeau, Lysanne
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Small-Molecule Ligands that Bind the RET Receptor Activate Neuroprotective Signals Independent of but Modulated by Coreceptor GFRα1
errMOLECULAR PHARMACOLOGY
IF3
err2020-07-01
err7
errOAAI
errJmaeff, Sean; Sidorova, Yulia; Lippiatt, Hayley; Barcelona, Pablo F.; Nedev, Hinyu; Saragovi, Lucia M.; Hancock, Mark A.; Saarma, Mart; Saragovi, H. Uri
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Small-molecule agonists of the RET receptor tyrosine kinase activate biased trophic signals that are influenced by the presence of GFRa1 co-receptors
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-05-01
err13
errOAAI
errJmaeff, Sean; Sidorova, Yulia; Nedev, Hinyu; Saarma, Mart; Saragovi, H. Uri
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Focused ultrasound delivery of a selective TrkA agonist rescues cholinergic function in a mouse model of Alzheimer's disease
errSCIENCE ADVANCES
IF12.5
err2020-01-24
err55
errOAAI
errXhima, K.; Markham-Coultes, K.; Nedev, H.; Heinen, S.; Saragovi, H. U.; Hynynen, K.; Aubert, I
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errSave
Vaccination with Tumor-Ganglioside Glycomimetics Activates a Selective Immunity that Affords Cancer Therapy
errCELL CHEMICAL BIOLOGY
IF7.2
err2019-07-01
err23
errOAAI
errTong, Wenyong; Maira, Mario; Roychoudhury, Rajarshi; Galan, Alba; Brahimi, Fouad; Gilbert, Michel; Cunningham, Anna-Maria; Josephy, Sylvia; Pirvulescu, Iulia; Moffett, Serge; Saragovi, H. Uri
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errSave
Neuroprotection: Pro-survival and Anti-neurotoxic Mechanisms as Therapeutic Strategies in Neurodegeneration
errFRONTIERS IN CELLULAR NEUROSCIENCE
IF4
err2019-06-06
err20
errOAAI
errSaragovi, Horacio Uri; Galan, Alba; Levin, Leonard A.
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Research Directions

No research directions
Co-authors
Cooperation Journals
N
Nahum Sonenberg
H-index: 178 · Papers: 957
K
Kullervo Hynynen
H-index: 118 · Papers: 845
V
Valerian E. Kagan
H-index: 118 · Papers: 830
P
Piotr Rutkowski
H-index: 113 · Papers: 1.8K
W
William L. Gerald
H-index: 109 · Papers: 514
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