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Stephen H. Hughes

national institutes of health

91H-index
514Paper Count
3.0WCitation Count
Published Papers 164
Publication Date
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HIV-1 uncoating location dictates sites of integration
errNature Communications
IF15.7
err2026-04-09
err0
errOAAI
errRyan C. Burdick; Sean C. Patro; Ellie Bare; Rokeya Siddiqui; Krista A. Delviks-Frankenberry; Olga A. Nikolaitchik; Stephen H. Hughes; Xiaolin Wu; Wei-Shau Hu; Vinay K. Pathak
errShare
errSave
Comparative Analyses of Antiviral Potencies of Second-Generation Integrase Strand Transfer Inhibitors (INSTIs) and the Developmental Compound 4d Against a Panel of Integrase Quadruple Mutants
errVIRUSES-BASEL
IF3.5
err2025-01-16
err0
errOAAI
errSmith, Steven J.; Zhao, Xue Zhi; Hughes, Stephen H.; Burke Jr, Terrence R.
errShare
errSave
Nirmatrelvir/ritonavir: real world drug-drug interaction management experience
errEXPERT REVIEW OF ANTI-INFECTIVE THERAPY
IF3.8
err2024-08-22
err0
PREAI
errBukhari, Shahid; Hughes, Stephen; Mughal, Nabeela; Moore, Luke S. P.; Davies, Gary; Zhang, Adrian Varghas; Ng, Megan; Karagozlu, Zekiye; Boffito, Marta
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errSave
HPV oncogenes expressed from only one of multiple integrated HPV DNA copies drive clonal cell expansion in cervical cancer
errMBIO
IF4.7
err2024-05-08
err13
errOAAI
errYu, Lulu; Majerciak, Vladimir; Lobanov, Alexei; Mirza, Sameer; Band, Vimla; Liu, Haibin; Cam, Maggie; Hughes, Stephen H.; Lowy, Douglas R.; Zheng, Zhi-Ming
errShare
errSave
N-Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants
errACS INFECTIOUS DISEASES
IF3.8
err2024-02-12
err1
errOAAI
errMahajan, Pankaj S.; Smith, Steven J.; Li, Min; Craigie, Robert; Hughes, Stephen H.; Zhao, Xue Zhi; Burke Jr, Terrence R.
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errSave
Multicolor Photoluminescent Carbon Dots a La Carte for Biomedical Applications
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2023-09-16
err3
errOAAI
errGarcia-Millan, Teodoro; Ramos-Soriano, Javier; Ghirardello, Mattia; Liu, Xia; Santi, Cristina Manuela; Eloi, Jean-Charles; Pridmore, Natalie; Harniman, Robert L.; Morgan, David J.; Hughes, Stephen; Davis, Sean A.; Oliver, Thomas A. A.; Kurian, Kathreena M.; Galan, M. Carmen
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errSave
The largest HIV-1-infected T cell clones in children on long-term combination antiretroviral therapy contain solo LTRs
errMBIO
IF4.7
err2023-08-02
err3
errOAAI
errBotha, Johannes C.; Demirov, Dimiter; Gordijn, Carli; Katusiime, Mary Grace; Bale, Michael J.; Wu, Xiaolin; Wells, Daria; Hughes, Stephen H.; Cotton, Mark F.; Mellors, John W.; Kearney, Mary F.; van Zyl, Gert U.
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errSave
Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants
errSCIENCE ADVANCES
IF12.5
err2023-07-21
err11
errOAAI
errLi, Min; Passos, Dario Oliveira; Shan, Zelin; Smith, Steven J.; Sun, Qinfang; Biswas, Avik; Choudhuri, Indrani; Strutzenberg, Timothy S.; Haldane, Allan; Deng, Nanjie; Li, Zhaoyang; Zhao, Xue Zhi; Briganti, Lorenzo; Kvaratskhelia, Mamuka; Burke Jr, Terrence R. R.; Levy, Ronald M.; Hughes, Stephen H.; Craigie, Robert; Lyumkis, Dmitry
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errSave
LINE1-Mediated Reverse Transcription and Genomic Integration of SARS-CoV-2 mRNA Detected in Virus-Infected but Not in Viral mRNA-Transfected Cells
errVIRUSES-BASEL
IF3.5
err2023-02-25
err10
errOAAI
errZhang, Liguo; Bisht, Punam; Flamier, Anthony; Barrasa, M. Inmaculada; Friesen, Max; Richards, Alexsia; Hughes, Stephen H.; Jaenisch, Rudolf
errShare
errSave
A Practical Approach to Bicyclic Carbamoyl Pyridones with Application to the Synthesis of HIV-1 Integrase Strand Transfer Inhibitors
errMOLECULES
IF4.6
err2023-02-02
err4
errOAAI
errMahajan, Pankaj S.; Smith, Steven J.; Hughes, Stephen H.; Zhao, Xuezhi; Burke, Terrence R., Jr.
errShare
errSave
Novel use of oral chloramphenicol for treatment-resistant Mycoplasma genitalium
errSEXUALLY TRANSMITTED INFECTIONS
IF2.9
err2023-01-30
err4
PREAI
errGoodfellow, Jonathan Joseph; Hughes, Stephen; Smith, Jo; Jones, Rachael; Moore, Luke S. P.; Rayment, Michael
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errSave
A reference human induced pluripotent stem cell line for collaborative studies
errCELL STEM CELL
IF20.4
err2022-12-01
err63
errOAAI
errPantazis, Caroline B.; Yang, Andrian; Lara, Erika; McDonough, Justin A.; Blauwendraat, Cornelis; Peng, Lirong; Oguro, Hideyuki; Kanaujiya, Jitendra; Zou, Jizhong; Sebesta, David; Pratt, Gretchen; Cross, Erin; Blockwick, Jeffrey; Buxton, Philip; Kinner-Bibeau, Lauren; Medura, Constance; Tompkins, Christopher; Hughes, Stephen; Santiana, Marianita; Faghri, Faraz; Nalls, Mike A.; Vitale, Daniel; Ballard, Shannon; Qi, Yue A.; Ramos, Daniel M.; Anderson, Kailyn M.; Stadler, Julia; Narayan, Priyanka; Papademetriou, Jason; Reilly, Luke; Nelson, Matthew P.; Aggarwal, Sanya; Rosen, Leah U.; Kirwan, Peter; Pisupati, Venkat; Coon, Steven L.; Scholz, Sonja W.; Priebe, Theresa; Ottl, Miriam; Dong, Jian; Meijer, Marieke; Janssen, Lara J. M.; Lourenco, Vanessa S.; van der Kant, Rik; Crusius, Dennis; Paquet, Dominik; Raulin, Ana-Caroline; Bu, Guojun; Held, Aaron; Wainger, Brian J.; Gabriele, Rebecca M. C.; Casey, Jackie M.; Wray, Selina; Abu-Bonsrah, Dad; Parish, Clare L.; Beccari, Melinda S.; Cleveland, Don W.; Li, Emmy; Rose, Indigo V. L.; Kampmann, Martin; Aristoy, Carles Calatayud; Verstreken, Patrik; Heinrich, Laurin; Chen, Max Y.; Schule, Birgitt; Dou, Dan; Holzbaur, Erika L. F.; Zanellati, Maria Clara; Basundra, Richa; Deshmukh, Mohanish; Cohen, Sarah; Khanna, Richa; Raman, Malavika; Nevin, Zachary S.; Matia, Madeline; Van Lent, Jonas; Timmerman, Vincent; Conklin, Bruce R.; Chase, Katherine Johnson; Zhang, Ke; Funes, Salome; Bosco, Daryl A.; Erlebach, Lena; Welzer, Marc; Kronenberg-Versteeg, Deborah; Lyu, Guochang; Arenas, Ernest; Coccia, Elena; Sarrafha, Lily; Ahfeldt, Tim; Marioni, John C.; Skarnes, William C.; Cookson, Mark R.; Ward, Michael E.; Merkle, Florian T.
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errSave
HIV infected CD4+T cell clones are more stable than uninfected clones during long-term antiretroviral therapy
errPLOS PATHOGENS
IF4.9
err2022-08-31
err7
errOAAI
errGuo, Shuang; Luke, Brian T.; Henry, Amy R.; Darko, Samuel; Brandt, Leah D.; Su, Ling; Sun, David; Wells, Daria; Joseph, Kevin W.; Demirov, Dimiter; Halvas, Elias K.; Douek, Daniel C.; Wu, Xiaolin; Mellors, John W.; Hughes, Stephen H.
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errSave
A Combination of Amino Acid Mutations Leads to Resistance to Multiple Nucleoside Analogs in Reverse Transcriptases from HIV-1 Subtypes B and C
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2022-01-18
err3
errOAAI
errBoyer, Paul L.; Rehm, Catherine A.; Sneller, Michael C.; Mican, JoAnn; Caplan, Margaret R.; Dewar, Robin; Ferris, Andrea L.; Clark, Patrick; Johnson, Adam; Maldarelli, Frank; Hughes, Stephen H.
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errSave
Small variations in reaction conditions tune carbon dot fluorescence
errNANOSCALE
IF5.1
err2022-01-01
err20
errOAAI
errGarcia-Millan, Teodoro; Swift, Thomas A.; Morgan, David J.; Harniman, Robert L.; Masheder, Benjamin; Hughes, Stephen; Davis, Sean A.; Oliver, Thomas A. A.; Galan, M. Carmen
errShare
errSave
INSTIs and NNRTIs Potently Inhibit HIV-1 Polypurine Tract Mutants in a Single Round Infection Assay
errVIRUSES-BASEL
IF3.5
err2021-12-14
err8
errOAAI
errSmith, Steven J.; Ferris, Andrea; Zhao, Xuezhi; Pauly, Gary; Schneider, Joel P.; Burke, Terrence R., Jr.; Hughes, Stephen H.
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errSave
REPLY TO BRIGGS ET AL.: Genomic integration and expression of SARS-CoV-2 sequences can explain prolonged or recurrent viral RNA detection
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2021-10-25
err4
errOAAI
errZhang, Liguo; Richards, Alexsia; Barrasa, M. Inmaculada; Hughes, Stephen H.; Young, Richard A.; Jaenisch, Rudolf
errShare
errSave
Clonal Expansion of Infected CD4+T Cells in People Living with HIV
errVIRUSES-BASEL
IF3.5
err2021-10-15
err12
errOAAI
errCoffin, John M.; Hughes, Stephen H.
errShare
errSave
Insertional activation of STAT3 and LCK by HIV-1 proviruses in T cell lymphomas
errSCIENCE ADVANCES
IF12.5
err2021-10-15
err20
errOAAI
errMellors, John W.; Guo, Shuang; Naqvi, Asma; Brandt, Leah D.; Su, Ling; Sun, Zhonghe; Joseph, Kevin W.; Demirov, Dimiter; Halvas, Elias K.; Butcher, Donna; Scott, Beth; Hamilton, Aaron; Heil, Marintha; Karim, Baktiar; Wu, Xiaolin; Hughes, Stephen H.
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errSave
Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures (vol 12, 4996, 2021)
errNATURE COMMUNICATIONS
IF15.7
err2021-10-05
err0
errOAAI
errBarski, Michal S.; Vanzo, Teresa; Zhao, Xue Zhi; Smith, Steven J.; Ballandras-Colas, Allison; Cronin, Nora B.; Pye, Valerie E.; Hughes, Stephen H.; Burke, Terrence R., Jr.; Cherepanov, Peter; Maertens, Goedele N.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Rudolf Jaenisch
H-index: 209 · Papers: 802
D
Don W. Cleveland
H-index: 165 · Papers: 525
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C. David Allis
H-index: 164 · Papers: 433
R
Richard A. Young
H-index: 158 · Papers: 702
S
Steven G. Deeks
H-index: 151 · Papers: 971
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