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Application of Chiral Transfer Reagents to Improve Stereoselectivity and Yields in the Synthesis of the Antituberculosis Drug Bedaquiline Robey, Juliana M. S.; Maity, Sanjay; Aleshire, Sarah L.; Ghosh, Angshuman; Yadaw, Ajay K.; Roy, Subho; Mear, Sarah Jane; Jamison, Timothy F.; Sirasani, Gopal; Senanayake, Chris H.; Stringham, Rodger W.; Gupton, B. Frank; Donsbach, Kai O.; Nelson, Ryan C.; Shanahan, Charles S. Share Save
Toward a Practical, Nonenzymatic Process for Investigational COVID-19 Antiviral Molnupiravir from Cytidine: Supply-Centered Synthesis (vol 25, pg 2679, 2021) Gopalsamuthiram, Vijayagopal; Kadam, Appasaheb L. L.; Noble, Jeffrey M. M.; Snead, David R. R.; Williams, Corshai; Jamison, Timothy F. F.; Senanayake, Chris; Yadaw, Ajay K. K.; Roy, Sarabindu; Sirasani, Gopal; Gupton, B. Frank; Burns, Justina; Cook, Daniel W. W.; Stringham, Rodger W. W.; Ahmad, Saeed; Krack, Rudy Share Save
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Diastereoselectivity is in the Details: Minor Changes Yield Major Improvements to the Synthesis of Bedaquiline Mear, Sarah Jane; Lucas, Tobias; Ahlqvist, Grace P.; Robey, Juliana M. S.; Dietz, Jule-Philipp; Khairnar, Pankaj, V; Maity, Sanjay; Williams, Corshai L.; Snead, David R.; Nelson, Ryan C.; Opatz, Till; Jamison, Timothy F. Share Save
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Toward a Practical, Nonenzymatic Process for Investigational COVID-19 Antiviral Molnupiravir from Cytidine: Supply-Centered Synthesis Gopalsamuthiram, Vijayagopal; Kadam, Appasaheb L.; Noble, Jeffrey K.; Snead, David R.; Williams, Corshai; Jamison, Timothy F.; Senanayake, Chris; Yadaw, Ajay K.; Roy, Sarabindu; Sirasani, Gopal; Gupton, B. Frank; Burns, Justina; Cook, Daniel W.; Stringham, Rodger W.; Ahmad, Saeed; Krack, Rudy Share Save
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Progress Toward a Large-Scale Synthesis of Molnupiravir (MK-4482, EIDD-2801) from Cytidine Ahlqvist, Grace P.; McGeough, Catherine P.; Senanayake, Chris; Armstrong, Joseph D.; Yadaw, Ajay; Roy, Sarabindu; Ahmad, Saeed; Snead, David R.; Jamison, Timothy F. Share Save
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Continuous Production of Five Active Pharmaceutical Ingredients in Flexible Plug-and-Play Modules: A Demonstration Campaign Rogers, Luke; Briggs, Naomi; Achermann, Ramona; Adamo, Andrea; Azad, Mohammad; Brancazio, David; Capellades, Gerard; Hammersmith, Gregory; Hart, Travis; Imbrogno, Joseph; Kelly, Liam P.; Liang, Guohua; Neurohr, Clemence; Rapp, Kersten; Russell, M. Grace; Salz, Carter; Thomas, Dale A.; Weimann, Lukas; Jamison, Timothy F.; Myerson, Allan S.; Jensen, Klavs F. Share Save
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A concise route to MK-4482 (EIDD-2801) from cytidine Vasudevan, N.; Ahlqvist, Grace P.; McGeough, Catherine P.; Paymode, Dinesh J.; Cardoso, Flavio S. P.; Lucas, Tobias; Dietz, Jule-Phillip; Opatz, Till; Jamison, Timothy F.; Gupton, Frank B.; Snead, David R. Share Save