Not logged in.png)
Share.png)
SaveShare Save Gain of chromosome 17 is an early genetic abnormality in neuroblastoma with PPM1D emerging as a strong candidate oncogene driving tumor progression
Milosevic, Jelena; Fransson, Susanne; Svensson, Johanna; Otte, Jorg; Olsen, Thale K.; Sveinbjornsson, Baldur; Hertwig, Falk; Bartenhagen, Christoph; Abel, Frida; Reinsbach, Susanne E.; Djos, Anna; Javanmardi, Niloufar; Shi, Yao; Hehir-Kwa, Jane Y.; Mensenkamp, Arjen; Tytgat, Godelieve AM.; Holmberg, Johan; Molenaar, Jan J.; Jongmans, Marjolijn; Fischer, Matthias; Baryawno, Ninib; Gisselsson, David; Martinsson, Tommy; Kogner, Per; Johnsen, John Inge Share Save Genomic tumor evolution dictates human medulloblastoma progressionRuchiy, Yana; Tsea, Ioanna; Preka, Efthalia; Verhoeven, Bronte Manouk; Olsen, Thale Kristin; Mei, Shenglin; Sinha, Indranil; Blomgren, Klas; Carlson, Lena-Maria; Dyberg, Cecilia; Johnsen, John Inge; Baryawno, Ninib Share Save Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastomaNagarajan, Divya; Parracho, Rebeca T.; Corujo, David; Xie, Minglu; Kutkaite, Ginte; Olsen, Thale K.; Bedos, Marta Rubies; Salehi, Maede; Baryawno, Ninib; Menden, Michael P.; Chen, Xingqi; Buschbeck, Marcus; Mao, Yumeng Share Save Joint single-cell genetic and transcriptomic analysis reveal pre-malignant SCP-like subclones in human neuroblastomaOlsen, Thale K.; Otte, Jorg; Mei, Shenglin; Embaie, Bethel Tesfai; Kameneva, Polina; Cheng, Huaitao; Gao, Teng; Zachariadis, Vasilios; Tsea, Ioanna; Bjorklund, Asa; Kryukov, Emil; Hou, Ziyi; Johansson, Anna; Sundstrom, Erik; Martinsson, Tommy; Fransson, Susanne; Stenman, Jakob; Fard, Shahrzad Shirazi; Johnsen, John Inge; Kogner, Per; Adameyko, Igor; Enge, Martin; Kharchenko, Peter V.; Baryawno, Ninib Share Save Share Save Share Save Single-cell analyses of metastatic bone marrow in human neuroblastoma reveals microenvironmental remodeling and metastaticMei, Shenglin; Alchahin, Adele M.; Embaie, Bethel Tesfai; Gavriliuc, Ioana Maria; Verhoeven, Bronte Manouk; Zhao, Ting; Li, Xiangyun; Jeffries, Nathan Elias; Pepich, Adena; Sarkar, Hirak; Olsen, Thale Kristin; Wickstrom, Malin; Stenman, Jakob; Reina-Bedoya, Oscar; Kharchenko, Peter V.; Saylor, Philip J.; Johnsen, John Inge; Sykes, David B.; Kogner, Per; Baryawno, Ninib Share Save SINGLE-CELL TRANSCRIPTOMIC ANALYSIS REVEALS DISTINCT GENOMIC LANDSCAPES, CELL TRAJECTORIES, AND TUMOUR-MICROENVIRONMENT INTERACTIONS IN FOUR SUBTYPES OF MEDULLOBLASTOMARuchiy, Yana; Tsea, Ioanna; Verhoeven, Bronte Manouk; Sinha, Indranil; Preka, Efthalia; Olsen, Thale Kristin; Mei, Shenglin; Blomgren, Klas; Johnsen, John Inge; Carlson, Lena-Maria; Dyberg, Cecilia; Baryawno, Ninib Share Save PATIENT-DERIVED XENOGRAFTS OF MATCHED PRIMARY-RECURRENT PEDIATRIC BRAIN TUMORS AS A RESOURCE FOR IDENTIFYING THERAPY RESISTANCE PROFILESZhao, Miao; Olsen, Thale; Bergstrom, Tobias; Rosen, Gabriela; Dalmo, Erika; Vikstrom, Elin; Larsson, Ida; Lin, Tina; Sundstrom, Anders; Holmberg, Karl; Weishaupt, Holger; Nelander, Sven; Giraud, Geraldine; Swartling, Fredrik Share Save Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of MedulloblastomaBorgenvik, Anna; Holmberg, Karl O.; Bolin, Sara; Zhao, Miao; Savov, Vasil; Rosen, Gabriela; Hutter, Sonja; Garancher, Alexandra; Rahmanto, Aldwin Suryo; Bergstrom, Tobias; Olsen, Thale Kristin; Mainwaring, Oliver J.; Sattanino, Damiana; Verbaan, Annemieke D.; Rusert, Jessica M.; Sundstrom, Anders; Bravo, Mar Ballester; Dang, Yonglong; Wenz, Amelie S.; Richardson, Stacey; Fotaki, Grammatiki; Hill, Rebecca M.; Dubuc, Adrian M.; Kalushkova, Antonia; Remke, Marc; Cancer, Matko; Jernberg-Wiklund, Helena; Giraud, Geraldine; Chen, Xingqi; Taylor, Michael D.; Sangfelt, Olle; Clifford, Steven C.; Schueller, Ulrich; Wechsler-Reya, Robert J.; Weishaupt, Holger; Swartling, Fredrik J. Share Save DHODH is an independent prognostic marker and potent therapeutic target in neuroblastomaOlsen, Thale Kristin; Dyberg, Cecilia; Embaie, Bethel Tesfai; Alchahin, Adele; Milosevic, Jelena; Ding, Jane; Otte, Jorg; Tummler, Conny; Myrberg, Ida Hed; Westerhout, Ellen M.; Koster, Jan; Versteeg, Rogier; Ding, Han-Fei; Kogner, Per; Johnsen, John Inge; Sykes, David B.; Baryawno, Ninib Share Save The immune cell atlas of human neuroblastomaVerhoeven, Bronte Manouk; Mei, Shenglin; Olsen, Thale Kristin; Gustafsson, Karin; Valind, Anders; Lindstrom, Axel; Gisselsson, David; Fard, Shahrzad Shirazi; Hagerling, Catharina; Kharchenko, Peter, V; Kogner, Per; Johnsen, John Inge; Baryawno, Ninib Share Save Omega-3 fatty acids decrease CRYAB, production of oncogenic prostaglandin E2 and suppress tumor growth in medulloblastomaLjungblad, Linda; Bergqvist, Filip; Tummler, Conny; Madawala, Samanthi; Olsen, Thale Kristin; Andonova, Teodora; Jakobsson, Per-Johan; Johnsen, John Inge; Pickova, Jana; Strandvik, Birgitta; Kogner, Per; Gleissman, Helena; Wickstrom, Malin Share Save Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma originKameneva, Polina; Artemov, Artem V.; Kastriti, Maria Eleni; Faure, Louis; Olsen, Thale K.; Otte, Jorg; Erickson, Alek; Semsch, Bettina; Andersson, Emma R.; Ratz, Michael; Frisen, Jonas; Tischler, Arthur S.; de Krijger, Ronald R.; Bouderlique, Thibault; Akkuratova, Natalia; Vorontsova, Maria; Gusev, Oleg; Fried, Kaj; Sundstrom, Erik; Mei, Shenglin; Kogner, Per; Baryawno, Ninib; Kharchenko, Peter V.; Adameyko, Igor Share Save Hodgkin Lymphoma Monozygotic Triplets Reveal Divergences in DNA Methylation SignaturesXia, Chuanyou; Olsen, Thale Kristin; Zirakzadeh, A. Ali; Almamoun, Radwa; Sjoholm, Louise K.; Dahlstrom, Jenny; Sjoberg, Jan; Claesson, Hans-Erik; Johnsen, John Inge; Winqvist, Ola; Xu, Dawei; Ekstrom, Tomas J.; Bjorkholm, Magnus; Straat, Klas Share Save Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable OutcomesClarke, Matthew; Mackay, Alan; Ismer, Britta; Pickles, Jessica C.; Tatevossian, Ruth G.; Newman, Scott; Bale, Tejus A.; Stoler, Iris; Izquierdo, Elisa; Temelso, Sara; Carvalho, Diana M.; Molinari, Valeria; Burford, Anna; Howell, Louise; Virasami, Alex; Fairchild, Amy R.; Avery, Aimee; Chalker, Jane; Kristiansen, Mark; Haupfear, Kelly; Dalton, James D.; Orisme, Wilda; Wen, Ji; Hubank, Michael; Kurian, Kathreena M.; Rowe, Catherine; Maybury, Mellissa; Crosier, Stephen; Knipstein, Jeffrey; Schueller, Ulrich; Kordes, Uwe; Kram, David E.; Snuderl, Matija; Bridges, Leslie; Martin, Andrew J.; Doey, Lawrence J.; Al-Sarraj, Safa; Chandler, Christopher; Zebian, Bassel; Cairns, Claire; Natrajan, Rachael; Boult, Jessica K. R.; Robinson, Simon P.; Sill, Martin; Dunkel, Ira J.; Gilheeney, Stephen W.; Rosenblum, Marc K.; Hughes, Debbie; Proszek, Paula Z.; Macdonald, Tobey J.; Preusser, Matthias; Haberler, Christine; Slavc, Irene; Packer, Roger; Ng, Ho-Keung; Caspi, Shani; Popovi, Mara; Kotnik, Barbara Faganel; Wood, Matthew D.; Baird, Lissa; Davare, Monika Ashok; Solomon, David A.; Olsen, Thale Kristin; Brandal, Petter; Farrell, Michael; Cryan, Jane B.; Capra, Michael; Karremann, Michael; Schittenhelm, Jens; Schuhmann, Martin U.; Ebinger, Martin; Dinjens, Winand N. M.; Kerl, Kornelius; Hettmer, Simone; Pietsch, Torsten; Andreiuolo, Felipe; Driever, Pablo Hernaiz; Korshunov, Andrey; Hiddingh, Lotte; Worst, Barbara C.; Sturm, Dominik; Zuckermann, Marc; Witt, Olaf; Bloom, Tabitha; Mitchell, Clare; Miele, Evelina; Colafati, Giovanna Stefania; Diomedi-Camassei, Francesca; Bailey, Simon; Moore, Andrew S.; Hassall, Timothy E. G.; Lowis, Stephen P.; Tsoli, Maria; Cowley, Mark J.; Ziegler, David S.; Karajannis, Matthias A.; Aquilina, Kristian; Hargrave, Darren R.; Carceller, Fernando; Marshall, Lynley, V; von Deimling, Andreas; Kramm, Christof M.; Pfister, Stefan M.; Sahm, Felix; Baker, Suzanne J.; Mastronuzzi, Angela; Carai, Andrea; Vinci, Maria; Capper, David; Popov, Sergey; Ellison, David W.; Jacques, Thomas S.; Jones, David T. W.; Jones, Chris Share Save Integrative discovery of treatments for high-risk neuroblastomaAlmstedt, Elin; Elgendy, Ramy; Hekmati, Neda; Rosen, Emil; Warn, Caroline; Olsen, Thale Kristin; Dyberg, Cecilia; Doroszko, Milena; Larsson, Ida; Sundstrom, Anders; Henriksson, Marie Arsenian; Pahlman, Sven; Bexell, Daniel; Vanlandewijck, Michael; Kogner, Per; Jornsten, Rebecka; Krona, Cecilia; Nelander, Sven Share Save Rho-associated kinase is a therapeutic target in neuroblastomaDyberg, Cecilia; Fransson, Susanne; Andonova, Teodora; Sveinbjornsson, Baldur; Lannerholm-Palm, Jessika; Olsen, Thale K.; Forsberg, David; Herlenius, Eric; Martinsson, Tommy; Brodin, Bertha; Kogner, Per; Johnsen, John Inge; Wickstrom, Malin Share Save 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}