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Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma Timpanaro, Andrea; Song, Edward Z.; Toumi, Ryma; Elena-Sanchez, Leonel; Piccand, Caroline; Nemec, Kelsey M.; Kordowski, Anja; Lau, Davina; Johnson, Scott; Winter, Lily; Rajendran, Ashmitha; Ronsley, Rebecca; Oda, Shannon K.; Gustafson, Joshua A.; Wendler, Jason P.; Koschmann, Carl; Evans, Myron; Pattwell, Siobhan; Jensen, Michael C.; Foster, Jessica B.; Dun, Matthew D.; Meechan, Michael; Biery, Matthew C.; Vitanza, Nicholas A. Share Save
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ESTABLISHING THE EPIGENETIC LANDSCAPE OF THE UNEXPLORED EZHIP-EXPRESSING DIFFUSE MIDLINE GLIOMA SUBTYPE Cassim, Afraah; Fox, Sarah; Colino-Sanguino, Yolanda; Jackson, Evangeline; Duchatel, Ryan; Sun, Claire; Firestein, Ron; Nazarian, Javad; Dun, Matthew; Gallego-Ortega, David; Valdes-Mora, Fatima Share Save
Leveraging the immunomodulatory effects of dordaviprone (ONC201) to induce long-term survival response in diffuse midline glioma patients and models Savary, Clara; Persson, Mika L.; Jackson, Evangeline R.; Duchatel, Ryan J.; Vo, Tuan; Findlay, Izac J.; Douglas, Alicia M.; Bramberger, Liesl; De La Nava, Daniel; Thomas, Bryce C.; Mcewen, Holly P.; Beitaki, Tyrone S.; De La Fuente, Laura Rodriguez; Colino-Sanguino, Yolanda; Mora, Fatima Valdes; Larsen, Martin R.; Faridi, Pouya; Holst, Jeff; Mayall, Jemma; Kline, Cassie N.; Franson, Andrea T.; Venneti, Sriram; Hondermarck, Hubert; Horvat, Jay; Nixon, Brett; Cartaxo, Rodrigo; Nazarian, Javad; Hulleman, Esther; Mueller, Sabine; Vitanza, Nicholas A.; Koschmann, Carl; Alonso, Marta M.; Carvalheiro, Tiago Ferreira; Van Der Lugt, Jasper; Dun, Matthew D. Share Save
ENHANCING GENOME ANALYSIS WITH WHOLE PROTEOME PROFILING FOR IMPROVED THERAPEUTIC DECISION MAKING IN DIFFUSE MIDLINE GLIOMA Findlay, Izac; Staudt, Dilana; Duchatel, Ryan; Jackson, Evangeline; Persson, Mika; McEwen, Holly; Delevaux, Katherine; Smith, Nathan; Vitanza, Nicholas; Cain, Jason; Hansen, Mitchell; Alvaro, Frank; Jakobsen, Lene; Larsen, Martin; Savary, Clara; Waszak, Sebastian; Dun, Matthew Share Save
DISRUPTING INTEGRIN SIGNALING IMPAIRS MIGRATION, MYC-DRIVEN PURINE BIOSYNTHESIS, AND STEMNESS IN H3K27M DIFFUSE MIDLINE GLIOMAS Cartaxo, Rodrigo T.; De La Nava, Daniel; Nieblas-Bedolla, Edwin; Niculcea, Michael; Ji, Sunjong; Natarajan, Siva Kumar; Adam, Tiffany; Clausen, Madison; Miclea, Madeline; Siada, Ruby; Schwark, Kallen; Gera, Ananya; Doherty, Robert; Lyssiotis, Costas A.; Favro, Noemi; Covato, Carmelo; Brunschwig, Lucas; Waszak, Sebastian M.; Nuechterlein, Nicholas; Filbin, Mariella; Vo, Tuan; Dun, Matthew D.; Venneti, Sriram; Hara, Toshiro; Koschmann, Carl Share Save
Exploiting Cell-of-Origin Vulnerabilities to Guide Multimodal Strategies in Diffuse Midline Glioma Dun, Matthew; Jackson, Evangeline; Findlay, Izac; Vo, Tuan; Savary, Clara; Douglas, Alicia; Germon, Zacary; Mannan, Abdul; Persson, Mika; Thomas, Bryce; Jayaraman, Ranjith; Newell-Rogers, Karen; Fonkem, Ekokobe; Wu, Cheng-Chia; Ameratunga, Malaka; Duchatel, Ryan Share Save
Precision Targeting of PI3K/mTOR in Diffuse Midline Glioma: GCT007 as a Novel Brain-Penetrant PIK3CA Inhibitor Jackson, Evangeline; Duchatel, Ryan; Vo, Tuan; Savary, Clara; Germon, Zacary; Riley, Madisen; McEwen, Holly; Persson, Mika; Findlay, Izac; Beitaki, Tyrone; Lally, Marissa; Douglas, Alicia; Rogers, M. Karen Newell; Fonkem, Ekokobe; Franson, Andrea; Kline, Cassie; Nazarian, Javad; Koschmann, Carl; Mueller, Sabine; Dun, Matthew Share Save
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TARGETING GENETIC DEPENDENCIES EXPOSES DIFFUSE MIDLINE GLIOMA CELL OF ORIGIN VULNERABILITIES Dun, Matthew D.; Jackson, Evangeline; Vo, Tuan; Savary, Clara; Riley, Madisen; Douglas, Alicia; Findlay, Izac; Germon, Zacary; Mannan, Abdul; Thomas, Bryce; Duchatel, Ryan; Jayaraman, Ranjith Share Save
Subchronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in mice Trigg, Natalie; Schjenken, John E.; Martin, Jacinta H.; Skerrett-Byrne, David A.; Smyth, Shannon P.; Bernstein, Ilana R.; Anderson, Amanda L.; Stanger, Simone J.; Simpson, Ewan N. A.; Tomar, Archana; Teperino, Raffaele; Conine, Colin C.; De Iuliis, Geoffry N.; Roman, Shaun D.; Bromfield, Elizabeth G.; Dun, Matthew D.; Eamens, Andrew L.; Nixon, Brett Share Save
If you build it, they will come: the convergence of funding, research and collaboration in paediatric brain cancer clinical trials Hansford, Jordan; Valvi, Santosh; de Boer, Jasper; McCowage, Geoff; Govender, Dinisha; Kirby, Maria; Ziegler, David; Manoharan, Neevika; Hassall, Timothy; Wainwright, Brandon; Alvaro, Frank; Wood, Paul J.; Eisenstat, David; Quang, Dong Anh Khuong; Jenkins, Misty; Dun, Matthew; Laughton, Stephen J.; Endersby, Raelene; Dodgshun, Andrew; Gottardo, Nicholas Share Save
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PNOC022 REPORT: A COMBINATION THERAPY TRIAL USING AN ADAPTIVE PLATFORM DESIGN FOR PATIENTS WITH DIFFUSE MIDLINE GLIOMA AT INITIAL DIAGNOSIS, POST-RADIATION THERAPY, OR PROGRESSION Kline, Cassie; Franson, Andrea; Banerjee, Anuradha; Reddy, Alyssa T.; Raber, Shannon; Hoffman, Carly; Minturn, Jane; van der Lugt, Jasper; de Vos-Kerkhof, Evelien; van Vuurden, Dannis; Gerber, Nicolas; Stucklin, Ana S. Guerreiro; Kilburn, Lindsay; Elster, Jennifer; Whipple, Nicholas; Cohen, Kenneth; Oren, Michal Yalon; Gardner, Sharon; Cluster, Andrew; Chi, Susan; Landi, Daniel; McCowage, Geoffrey; Vo, Josh; Resnick, Adam; Phillips, Joanna; Bhatia, Aashim; George, Elizabeth; Vossough, Arastoo; Nabavizadeh, Ali; Braunstein, Steve; Gupta, Nalin; Prados, Michael; Waszak, Sebastian; Long-Boyle, Janel; Molinaro, Annette; Dun, Matthew; Koschmann, Carl; Nazarian, Javad; Mueller, Sabine Share Save
DRD2 ANTAGONISM RESCUES IMMUNE-TUMOR SURVEILLANCE, WARMING THE TUMOR IMMUNE MICROENVIRONMENT OF DIFFUSE MIDLINE GLIOMA MODELS Persson, Mika L.; Jackson, Evangeline R.; Duchatel, Ryan J.; de la Nava, Daniel; Thomas, Bryce C.; Savary, Clara; Mcewen, Holly P.; Beitaki, Tyrone S.; Kearney, Padraic S.; Findlay, Izac J.; Douglas, Alicia M.; Larsen, Martin R.; Faridi, Pouya; Holst, Jeff; Mayall, Jemma; Hondermarck, Hubert; Horvat, Jay; Nixon, Brett; Cartaxo, Rodrigo T.; Nazarian, Javad; Hulleman, Esther; Mueller, Sabine; Vitanza, Nicholas A.; Koshmann, Carl; Alonso, Marta M.; Carvalheiro, Tiago; van der Lugt, Jasper; Dun, Matthew D. Share Save
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