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Chris D. Vulpe

college of veterinary medicine

61H-index
267Paper Count
1.5WCitation Count
Published Papers 100
Publication Date
Parkinson’s disease LRRK2 mutations dysregulate iron homeostasis and promote oxidative stress and ferroptosis in human neurons and astrocytes
err2026-07-24
err0
errOAAI
errAdamantios Mamais; Richard D. Batchelor; Aravindraja Chairmandurai; Thomas B. Ladd; Austin J. Shute; Nitya Subrahmanian; Nunziata Maio; Christopher D. Vulpe; Matthew J. LaVoie
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Iron Deficiency-Induced Hair Loss Is Associated with ROS-Mediated Disruption of Wnt/β-Catenin Signaling
err2026-07-23
err0
errOAAI
errSang-Ah Kwon; So Young Bu; Yeon-Hee Kim; Joo Weon Lim; Christopher D. Vulpe; Seung-Min Lee
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cellMCD Effectively Discovers Drug Resistance and Sensitivity Genes for Acute Myeloid Leukemia
errGenes
IF2.8
err2026-01-02
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errOAAI
errDora Obodo; Nam H. K. Nguyen; Xueyuan Cao; Phani Krishna Parcha; Christopher D. Vulpe; Jatinder K. Lamba; Stanley B. Pounds
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Toxicophore-informed machine learning integrating Tox21 assay readouts for organ system–specific carcinogenicity prediction
err2025-12-11
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PREAI
errChi-Yun Chen; Wei-Chun Chou; Venkata Nithin Kamineni; Pei-Yu Wu; Zhicheng Zhang; Xue Wu; Chris D. Vulpe; Zhoumeng Lin
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Novel Lipid Biomarkers of Chronic Kidney Disease of Unknown Etiology Based on Urinary Small Extracellular Vesicles: A Pilot Study of Sugar Cane Workers
err2025-08-21
err0
PREAI
errJie Zhou; Kevin J. Kroll; Jaime Butler-Dawson; Lyndsay Krisher; Abdel A. Alli; Chris Vulpe; Nancy D. Denslow
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Effects of dietary iron deficiency or overload on bone: Dietary details matter
errBONE
IF3.6
err2024-07-01
err1
errOAAI
errBaschant, Ulrike; Fuqua, Brie K.; Ledesma-Colunga, Maria; Vulpe, Christopher D.; McLachlan, Stela; Hofbauer, Lorenz C.; Lusis, Aldons J.; Rauner, Martina
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Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML
err2023-04-27
err6
errOAAI
errNguyen, Nam H. K.; Rafiee, Roya; Tagmount, Abderrahmane; Sobh, Amin; Loguinov, Alex; Sosa, Angelica K. de Jesus; Elsayed, Abdelrahman H.; Gbadamosi, Mohammed; Seligson, Nathan; Cogle, Christopher R.; Rubnitz, Jeffery; Ribeiro, Raul; Downing, James; Cao, Xueyuan; Pounds, Stanley B.; Vulpe, Christopher D.; Lamba, Jatinder K.
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Genome-wide CRISPR Screen Reveal Targets of Chiral Gold(I) Anticancer Compound in Mammalian Cells
err2022-10-20
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errOAAI
errKim, Jong Hyun; Ofori, Samuel; Tagmount, Abderrahmane; Vulpe, Chris D.; Awuah, Samuel G.
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Identifying Toxicity Mechanisms Associated with Early Lanthanide Exposure through Multidimensional Genome-Wide Screening
err2022-09-16
err12
errOAAI
errPallares, Roger M.; An, Dahlia D.; Hebert, Solene; Loguinov, Alex; Proctor, Michael; Villalobos, Jonathan A.; Bjornstad, Kathleen A.; Rosen, Chris J.; Vulpe, Chris D.; Abergel, Rebecca J.
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The biology of mammalian multi-copper ferroxidases
err2022-02-15
err42
errOAAI
errHelman, Sheridan L.; Zhou, Jie; Fuqua, Brie K.; Lu, Yan; Collins, James F.; Chen, Huijun; Vulpe, Christopher D.; Anderson, Gregory J.; Frazer, David M.
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Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL-Specific Degrader DT2216
err2021-10-19
err42
errOAAI
errThummuri, Dinesh; Khan, Sajid; Underwood, Patrick W.; Zhang, Peiyi; Wiegand, Janet; Zhang, Xuan; Budamagunta, Vivekananda; Sobh, Amin; Tagmount, Abderrahmane; Loguinov, Alexander; Riner, Andrea N.; Akki, Ashwin S.; Williamson, Elizabeth; Hromas, Robert; Vulpe, Christopher D.; Zheng, Guangrong; Trevino, Jose G.; Zhou, Daohong
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Effects of ultraviolet-filters on Daphnia magna development and endocrine-related gene expression
err2021-09-01
err15
PREAI
errLambert, F. N.; Gracy, H. R.; Gracy, A. J.; Yoon, S. H.; Scott, R. W.; Rincon, D. M.; Vulpe, C. D.
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The Placental Ferroxidase Zyklopen Is Not Essential for Iron Transport to the Fetus in Mice
err2021-09-01
err9
errOAAI
errHelman, Sheridan L.; Wilkins, Sarah J.; McKeating, Daniel R.; Perkins, Anthony, V; Whibley, Page E.; Cuffe, James S. M.; Simmons, David G.; Fuqua, Brie K.; Vulpe, Christopher D.; Wallace, Daniel F.; O'Callaghan, Jessica L.; Pelzer, Elise S.; Anderson, Gregory J.; Frazer, David M.
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Treatment with HIV-Protease Inhibitor Nelfinavir Identifies Membrane Lipid Composition and Fluidity as a Therapeutic Target in Advanced Multiple Myeloma
err2021-06-22
err9
errOAAI
errBesse, Lenka; Besse, Andrej; Stolze, Sara C.; Sobh, Amin; Zaal, Esther A.; van der Ham, Alwin J.; Ruiz, Mario; Phuyal, Santosh; Buechler, Lorina; Sathianathan, Marc; Florea, Bogdan I.; Boren, Jan; Stahlman, Marcus; Huber, Julia; Bolomsky, Arnold; Ludwig, Heinz; Hannich, J. Thomas; Loguinov, Alex; Everts, Bart; Berkers, Celia R.; Pilon, Marc; Farhan, Hesso; Vulpe, Christopher D.; Overkleeft, Herman S.; Driessen, Christoph
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Organochlorine Pesticide Dieldrin Suppresses Cellular Interfiron-Reland Antiviral Gene Expression
err2021-05-29
err6
PREAI
errRusso, Max; Humes, Sara T.; Figueroa, Ariana M.; Tagmount, Abderrahmane; Zhang, Ping; Loguinov, Alex; Lednicky, John A.; Sabo-Attwood, Tara; Vulpe, Chris D.; Liu, Bin
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Genetic screens reveal CCDC115 as a modulator of erythroid iron and heme trafficking
err2020-07-09
err10
errOAAI
errSobh, Amin; Loguinov, Alex; Zhou, Jie; Jenkitkasemwong, Supak; Zeidan, Rola; El Ahmadie, Nader; Tagmount, Abderrahmane; Knutson, Mitchell; Fraenkel, Paula G.; Vulpe, Christopher D.
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Functional Pathway Identification With CRISPR/Cas9 Genome-wide Gene Disruption in Human Dopaminergic Neuronal Cells Following Chronic Treatment With Dieldrin
err2020-05-18
err12
errOAAI
errRusso, Max; Sobh, Amin; Zhang, Ping; Loguinov, Alex; Tagmount, Abderrahmane; Vulpe, Chris D.; Liu, Bin
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Multi-copper ferroxidase deficiency leads to iron accumulation and oxidative damage in astrocytes and oligodendrocytes
err2019-07-01
err34
errOAAI
errChen, Zheng; Jiang, Ruiwei; Chen, Mengxia; Zheng, Jiashuo; Chen, Min; Braidy, Nady; Liu, Shunli; Liu, Guohao; Maimaitiming, Zaitunamu; Shen, Tianqi; Dunaief, Joshua L.; Vulpe, Christopher D.; Anderson, Gregory J.; Chen, Huijun
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Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype
err2019-05-24
err21
errOAAI
errSharma, Prashant; Reichert, Marie; Lu, Yan; Markello, Thomas C.; Adams, David R.; Steinbach, Peter J.; Fuqua, Brie K.; Parisi, Xenia; Kaler, Stephen G.; Vulpe, Christopher D.; Anderson, Gregory J.; Gahl, William A.; Malicdan, May Christine V.
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Propagation of functional estrogen receptor positive normal human breast cells in 3D cultures
err2019-04-16
err5
errOAAI
errMeng, Peng; Vaapil, Marica; Tagmount, Abderrahmane; Loguinov, Alex; Vulpe, Chris; Yaswen, Paul
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