Not logged in CSF proteomics of semorinemab Alzheimer's disease trials identifies cell-type specific signatures Abdel-Haleem, Alyaa M.; Casavant, Ellen; Toth, Balazs; Teng, Edmond; Monteiro, Cecilia; Pandya, Nikhil J.; Glock, Caspar; Hoogenraad, Casper C.; Friedman, Brad A.; Yeh, Felix L.; Anania, Veronica G.; Novikova, Gloriia Share Save
Secreted neurofilament light chain after neuronal damage induces myeloid cell activation and neuroinflammation Kahn, Olga I.; Dominguez, Sara L.; Glock, Caspar; Hayne, Margaret; Vito, Steve; Ghosh, Arundhati Sengupta; Adrian, Max; Burgess, Braydon L.; Meilandt, William J.; Friedman, Brad A.; Hoogenraad, Casper C. Share Save
Pharmacodynamic effects of semorinemab on plasma and CSF biomarkers of Alzheimer's disease pathophysiology Schauer, Stephen P.; Toth, Balazs; Lee, Julie; Honigberg, Lee A.; Ramakrishnan, Vidya; Jiang, Jenny; Kollmorgen, Gwendlyn; Bayfield, Anna; Wild, Norbert; Hoffman, Jennifer; Ceniceros, Ryan; Dolton, Michael; Bohorquez, Sandra M. Sanabria; Hoogenraad, Casper C.; Wildsmith, Kristin R.; Teng, Edmond; Monteiro, Cecilia; Anania, Veronica; Yeh, Felix L. Share Save
Fully defined NGN2 neuron protocol reveals diverse signatures of neuronal maturation Shan, Xiwei; Zhang, Ai; Rezzonico, Mitchell G.; Tsai, Ming-Chi; Sanchez-Priego, Carlos; Zhang, Yingjie; Chen, Michelle B.; Choi, Meena; Lopez, Jose Miguel Andrade; Phu, Lilian; Cramer, Amber L.; Zhang, Qiao; Pattison, Jillian M.; Rose, Christopher M.; Hoogenraad, Casper C.; Jeong, Claire G. Share Save
A fluorescent splice-switching mouse model enables high-throughput, sensitive quantification of antisense oligonucleotide delivery and activity Byrnes, Amy E.; Roudnicky, Filip; Gogineni, Alvin; Soung, Allison L.; Xiong, Monica; Hayne, Margaret; Heaster-Ford, Tiffany; Shatz-Binder, Whitney; Dominguez, Sara L.; Imperio, Jose; Gierke, Sarah; Roberts, Jasmine; Guo, Jinglong; Ghosh, Soumitra; Yu, Charles; Roose-Girma, Merone; Elstrott, Justin; Easton, Amy; Hoogenraad, Casper C. Share Save
Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release Adrian, Max; Weber, Martin; Tsai, Ming-Chi; Glock, Caspar; Kahn, Olga I.; Phu, Lilian; Cheung, Tommy K.; Meilandt, William J.; Rose, Christopher M.; Hoogenraad, Casper C. Share Save
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Correlating the Structure and Gene Silencing Activity of Oligonucleotide-Loaded Lipid Nanoparticles Using Small-Angle X-ray Scattering Hammel, Michal; Fan, Yuchen; Sarode, Apoorva; Byrnes, Amy E.; Zang, Nanzhi; Kou, Ponien; Nagapudi, Karthik; Leung, Dennis; Hoogenraad, Casper C.; Chen, Tao; Yen, Chun-Wan; Hura, Greg L. Share Save
Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injection Byrnes, Amy E.; Dominguez, Sara L.; Yen, Chun -Wan; Laufer, Benjamin I.; Foreman, Oded; Reichelt, Mike; Lin, Han; Sagolla, Meredith; Hoetzel, Kathy; Ngu, Hai; Soendergaard, Christoffer; Estevez, Alberto; Lin, Hsiu-Chao; Goyon, Alexandre; Bian, Juan; Lin, Jessica; Hinz, Flora I.; Friedman, Brad A.; Easton, Amy; Hoogenraad, Casper C. Share Save
LIS1, CLIP-170's key to the dynein/dynactin pathway Coquelle, FM; Caspi, M; Cordelières, FP; Dompierre, JP; Dujardin, DL; Koifman, C; Martin, P; Hoogenraad, CC; Akhmanova, A; Galjart, N; De Mey, JR; Reiner, O Share Save
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Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells Noordstra, Ivar; van den Berg, Cyntha M.; Boot, Fransje W. J.; Katrukha, Eugene A.; Yu, Ka Lou; Tas, Roderick P.; Portegies, Sybren; Viergever, Bastiaan J.; de Graaff, Esther; Hoogenraad, Casper C.; de Koning, Eelco J. P.; Carlotti, Francoise; Kapitein, Lukas C.; Akhmanova, Anna Share Save
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ER - lysosome contacts at a pre-axonal region regulate axonal lysosome availability Ozkan, Nazmiye; Koppers, Max; van Soest, Inge; van Harten, Alexandra; Jurriens, Daphne; Liv, Nalan; Klumperman, Judith; Kapitein, Lukas C.; Hoogenraad, Casper C.; Farias, Ginny G. Share Save
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WDR47 protects neuronal microtubule minus ends from katanin-mediated severing Buijs, Robin R.; Hummel, Jessica J. A.; Burute, Mithila; Pan, Xingxiu; Cao, Yujie; Stucchi, Riccardo; Altelaar, Maarten; Akhmanova, Anna; Kapitein, Lukas C.; Hoogenraad, Casper C. Share Save
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Centrosome-mediated microtubule remodeling during axon formation in human iPSC-derived neurons Lindhout, Feline W.; Portegies, Sybren; Kooistra, Robbelien; Herstel, Lotte J.; Stucchi, Riccardo; Hummel, Jessica J. A.; Scheefhals, Nicky; Katrukha, Eugene A.; Altelaar, Maarten; MacGillavry, Harold D.; Wierenga, Corette J.; Hoogenraad, Casper C. Share Save
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