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Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma Barroux, Melissa; Househam, Jacob; Lakatos, Eszter; Ronel, Tahel; Baker, Ann-Marie; Salie, Henrike; Mossner, Maximilian; Smith, Kane; Kimberley, Chris; Nowinski, Salpie; Berner, Alison; Gunasri, Vinaya; Borgmann, Martin; Liffers, Sven; Jansen, Marnix; Caravagna, Giulio; Steiger, Katja; Slotta-Huspenina, Julia; Weichert, Wilko; Zapata, Luis; Giota, Eleftheria; Lorenzen, Sylvie; Alberstmeier, Markus; Chain, Benny; Friess, Helmut; Bengsch, Bertram; Schmid, Roland M.; Siveke, Jens T.; Quante, Michael; Graham, Trevor A. Share Save
Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis Al Bakir, Ibrahim; Curtius, Kit; Cresswell, George D.; Grant, Heather E.; Nasreddin, Nadia; Smith, Kane; Nowinski, Salpie; Guo, Qingli; Belnoue-Davis, Hayley L.; Fisher, Jennifer; Clarke, Theo; Kimberley, Christopher; Mossner, Maximilian; Dunne, Philip D.; Loughrey, Maurice B.; Speight, Ally; East, James E.; Wright, Nicholas A.; Rodriguez-Justo, Manuel; Jansen, Marnix; Moorghen, Morgan; Baker, Ann-Marie; Leedham, Simon J.; Hart, Ailsa L.; Graham, Trevor A. Share Save
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer Kayhanian, Hamzeh; Cross, William; van der Horst, Suzanne E. M.; Barmpoutis, Panagiotis; Lakatos, Eszter; Caravagna, Giulio; Zapata, Luis; Van Hoeck, Arne; Middelkamp, Sjors; Litchfield, Kevin; Steele, Christopher; Waddingham, William; Patel, Dominic; Milite, Salvatore; Jin, Chen; Baker, Ann-Marie; Alexander, Daniel C.; Khan, Khurum; Hochhauser, Daniel; Novelli, Marco; Werner, Benjamin; van Boxtel, Ruben; Hageman, Joris H.; Buissant des Amorie, Julian R.; Linares, Josep; Ligtenberg, Marjolijn J. L.; Nagtegaal, Iris D.; Lacle, Miangela M.; Moons, Leon M. G.; Brosens, Lodewijk A. A.; Pillay, Nischalan; Sottoriva, Andrea; Graham, Trevor A.; Rodriguez-Justo, Manuel; Shiu, Kai-Keen; Snippert, Hugo J. G.; Jansen, Marnix Share Save
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Profiling of Copy Number Alterations Using Low-Coverage Whole-Genome Sequencing Informs Differential Diagnosis and Prognosis in Primary Cutaneous Follicle Center Lymphoma Batai, Bence; Kiss, Laura; Varga, Luca; Nagy, Akos; Househam, Jacob; Baker, Ann-Marie; Laszlo, Tamas; Udvari, Anna; Horvath, Robert; Nagy, Tibor; Csomor, Judit; Szakonyi, Jozsef; Schneider, Tamas; Graham, Trevor A.; Alpar, Donat; Fitzgibbon, Jude; Szepesi, Agota; Bodor, Csaba Share Save
Proof-of-concept and preliminary efficacy of triple IAP blockade to maximize immunogenic cell death and induce efficient adaptive immune response: First report on the ASTEROID phase 1 trial Tiu, Crescens; Yau, Wing; Sanchez-Perez, Victoria; Codacci-Pisanelli, Giovanni; Leung, Ching; Andrews, Eden S.; Basu, Bristi; Zachariou, Anna; Prout, Toby; Parmar, Mona; Turner, Alison; Lai, Xiaoran; Yin, Zhulin; Swales, Karen E.; Haider, Syed; Lund, Thomas; Dos Reis, Diego C.; Silveira, Tatiany L.; Dunlop, Alan S.; Baker, Ann-Marie; Gurel, Bora; Ferreira, Ana; Bertan, Claudia; Tunariu, Nina; Johnston, Edward W.; Ring, Alistair; Tenev, Tencho; Smyth, Tomoko; Jueliger, Simone; Banerji, Udai; de Bono, Johann S.; Paschalis, Alec; Sharp, Adam; Minchom, Anna; Yap, Christina; Meier, Pascal; Lopez, Juanita S. Share Save
FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA Baker, Ann-Marie; Nageswaran, Gayathri; Nenclares, Pablo; Ronel, Tahel; Smith, Kane; Kimberley, Christopher; Lacle, Miangela M.; Bhide, Shreerang; Harrington, Kevin J.; Melcher, Alan; Rodriguez-Justo, Manuel; Chain, Benny; Graham, Trevor A. Share Save
Lower incidence of small intestinal adenocarcinomas may be due to constrained copy number karyotype and increased immune surveillance Nowinski, Salpie; Balarajah, Vickna; Baker, Ann-Marie; Katainen, Riku; Hughes, Christine; Guo, Qingli; Zapata, Luis; Lakatos, Eszter; Kocher, Hemant M.; Graham, Trevor A. Share Save
Molecular characteristics of early-onset pancreatic ductal adenocarcinoma Debernardi, Silvana; Liszka, Lukasz; Ntala, Chara; Steiger, Katja; Esposito, Irene; Carlotti, Emanuela; Baker, Ann-Marie; McDonald, Stuart; Graham, Trevor; Dmitrovic, Branko; Feakins, Roger M.; Crnogorac-Jurcevic, Tatjana Share Save
Virtual alignment of pathology image series for multi-gigapixel whole slide images Gatenbee, Chandler D.; Baker, Ann-Marie; Prabhakaran, Sandhya; Swinyard, Ottilie; Slebos, Robbert J. C.; Mandal, Gunjan; Mulholland, Eoghan; Andor, Noemi; Marusyk, Andriy; Leedham, Simon; Conejo-Garcia, Jose R.; Chung, Christine H.; Robertson-Tessi, Mark; Graham, Trevor A.; Anderson, Alexander R. A. Share Save
Tumor evolution and immune microenvironment dynamics define response to neoadjuvant treatment of esophageal adenocarcinoma Barroux, Melissa; Househam, Jacob; Lakatos, Eszter; Ronel, Tahel; Baker, Ann-Marie; Salie, Henrike; Mossner, Max; Smith, Kane; Kimberley, Chris; Nowinski, Salpie; Berner, Alison; Gunasri, Vinaya; Jansen, Marnix; Caravagna, Giulio; Slotta-Huspenina, Julia; Weichert, Wilko; Alberstmeier, Markus; Chain, Benny; Friess, Helmut; Bengsch, Bertram; Schmid, Roland M.; Siveke, Jens T.; Quante, Michael; Graham, Trevor A. Share Save
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Multiple roles for plasticity in metastasis and therapy resistance in long-term survivors of metastatic colorectal cancer Berner, Alison May; Gabbutt, Calum; Nowinski, Salpie; Househam, Jacob; Trahearn, Nick; Cresswell, George D.; Nadhamuni, Vinaya Srirangam; Kimberley, Christopher; Fassan, Matteo; Baker, Ann-Marie; Sottoriva, Andrea; Thirlwell, Christina; Bridgewater, John; Graham, Trevor Share Save
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