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ERG-driven luminal prostate cancers emerge from Ck5+/Nkx3.1+basal cells Feng, Weiran; Ladewig, Erik; Salsabeel, Nazifa; Zhao, Huiyong; Lee, Young Sun; Gopalan, Anuradha; Luo, Hanzhi; Kang, Wenfei; Fan, Ning; Rosiek, Eric; Masilionis, Ignas; Manova-Todorova, Katia; Chaligne, Ronan; de Stanchina, Elisa; Carver, Brett S.; Chen, Yu; Gao, Dong; Leslie, Christina S.; Sawyers, Charles L. Share Save
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hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease Fan, Yujie; Hackland, James; Baggiolini, Arianna; Hung, Lin Y.; Zhao, Huiyong; Zumbo, Paul; Oberst, Polina; Minotti, Andrew P.; Hergenreder, Emiliano; Najjar, Sarah; Huang, Zixing; Cruz, Nelly M.; Zhong, Aaron; Sidharta, Mega; Zhou, Ting; de Stanchina, Elisa; Betel, Doron; White, Richard M.; Gershon, Michael; Margolis, Kara Gross; Studer, Lorenz Share Save
Molecular Characterization of Acquired Resistance to KRAS G12C-EGFR Inhibition in Colorectal Cancer Yaeger, Rona; Mezzadra, Riccardo; Sinopoli, Jenna; Bian, Yu; Marasco, Michelangelo; Kaplun, Esther; Gao, Yijun; Zhao, HuiYong; Paula, Arnaud Da Cruz; Zhu, Yingjie; Perez, Almudena Chaves; Chadalavada, Kalyani; Tse, Edison; Chowdhry, Sudhir; Bowker, Sydney; Chang, Qing; Qeriqi, Besnik; Weigelt, Britta; Nanjangud, Gouri J.; Berger, Michael F.; Der-Torossian, Hirak; Anderes, Kenna; Socci, Nicholas D.; Shia, Jinru; Murciano-Goroff, Yonina R.; Li, Bob; Christensen, James G.; Reis-Filho, Jorge S.; Solit, David B.; de Stanchina, Elisa; Lowe, Scott W.; Rosen, Neal; Misale, Sandra Share Save
ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1 Su, Wenjing; Mukherjee, Radha; Yaeger, Rona; Son, Jieun; Xu, Jianing; Na, Na; Timaul, Neilawattie Merna; Hechtman, Jaclyn; Paroder, Viktoriya; Lin, Mika; Mattar, Marissa; Qiu, Juan; Chang, Qing; Zhao, Huiyong; Zhang, Jonathan; Little, Megan; Adachi, Yuta; Han, Sae-Won; Taylor, Barry S.; Ebi, Hiromichi; Abdel-Wahab, Omar; de Stanchina, Elisa; Rudin, Charles M.; Janne, Pasi A.; McCormick, Frank; Yao, Zhan; Rosen, Neal Share Save
Targeting the mTOR Pathway in Hurthle Cell Carcinoma Results in Potent Antitumor Activity Dong, Yiyu; Gong, Yongxing; Kuo, Fengshen; Makarov, Vladimir; Reznik, Ed; Nanjangud, Gouri J.; Aras, Omer; Zhao, Huiyong; Qu, Rui; Fagin, James A.; Sherman, Eric J.; Xu, Bin; Ghossein, Ronald; Chan, Timothy A.; Ganly, Ian Share Save
Prognostic and therapeutic significance of COP9 signalosome subunit CSN5 in prostate cancer Mazzu, Ying Z.; Liao, Yu-Rou; Nandakumar, Subhiksha; Jehane, Lina E.; Koche, Richard P.; Rajanala, Sai Harisha; Li, Ruifang; Zhao, HuiYong; Gerke, Travis A.; Chakraborty, Goutam; Lee, Gwo-Shu Mary; Nanjangud, Gouri J.; Gopalan, Anuradha; Chen, Yu; Kantoff, Philip W. Share Save
Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis Duan, Shanshan; Moro, Loredana; Qu, Rui; Simoneschi, Daniele; Cho, Hyunwoo; Jiang, Shaowen; Zhao, Huiyong; Chang, Qing; de Stanchina, Elisa; Arbini, Arnaldo A.; Pagano, Michele Share Save
Rapid interrogation of cancer cell of origin through CRISPR editing Feng, Weiran; Cao, Zhen; Lim, Pei Xin; Zhao, Huiyong; Luo, Hanzhi; Mao, Ninghui; Lee, Young Sun; Rivera, Aura Agudelo; Choi, Danielle; Wu, Chao; Han, Teng; Romero, Rodrigo; de Stanchina, Elisa; Carver, Brett S.; Wang, Qiao; Jasin, Maria; Sawyers, Charles L. Share Save
EGFR Blockade Reverts Resistance to KRASG12C Inhibition in Colorectal Cancer Amodio, Vito; Yaeger, Rona; Arcella, Pamela; Cancelliere, Carlotta; Lamba, Simona; Lorenzato, Annalisa; Arena, Sabrina; Montone, Monica; Mussolin, Benedetta; Bian, Yu; Whaley, Adele; Pinnelli, Marika; Murciano-Goroff, Yonina R.; Vakiani, Efsevia; Valeri, Nicola; Liao, Wei-Li; Bhalkikar, Anuja; Thyparambil, Sheeno; Zhao, Hui-Yong; de Stanchina, Elisa; Marsoni, Silvia; Siena, Salvatore; Bertotti, Andrea; Trusolino, Livio; Li, Bob T.; Rosen, Neal; Di Nicolantonio, Federica; Bardelli, Alberto; Misale, Sandra Share Save
Stomatin-like Protein 2 Promotes Tumor Cell Survival by Activating the JAK2-STAT3-PIM1 Pathway, Suggesting a Novel Therapy in CRC Liu, Qiang; Li, Anqi; Wang, Lisha; He, Wei; Zhao, Ling; Wu, Chao; Lu, Shasha; Ye, Xuanguang; Zhao, Huiyong; Shen, Xiaohan; Xiao, Xiuying; Liu, Zebing Share Save
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer Xu, Guotai; Chhangawala, Sagar; Cocco, Emiliano; Razavi, Pedram; Cai, Yanyan; Otto, Jordan E.; Ferrando, Lorenzo; Selenica, Pier; Ladewig, Erik; Chan, Carmen; Paula, Arnaud Da Cruz; Witkin, Matthew; Cheng, Yuanming; Park, Jane; Serna-Tamayo, Cristian; Zhao, HuiYong; Wu, Fan; Sallaku, Mirna; Qu, Xuan; Zhao, Alison; Collings, Clayton K.; D'Avino, Andrew R.; Jhaveri, Komal; Koche, Richard; Levine, Ross L.; Reis-Filho, Jorge S.; Kadoch, Cigall; Scaltriti, Maurizio; Leslie, Christina S.; Baselga, Jose; Toska, Eneda Share Save
V211D Mutation in MEK1 Causes Resistance to MEK Inhibitors in Colon Cancer Gao, Yijun; Maria, Ann; Na, Na; Paula, Arnaud da Cruz; Gorelick, Alexander N.; Hechtman, Jaclyn F.; Carson, Julianne; Lefkowitz, Robert A.; Weigelt, Britta; Taylor, Barry S.; Zhao, HuiYong; Reis-Filho, Jorge S.; de Stanchina, Elisa; Rosen, Neal; Yao, Zhan; Yaeger, Rona Share Save
Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition Yaeger, Rona; Yao, Zhan; Hyman, David M.; Hechtman, Jaclyn F.; Vakiani, Efsevia; Zhao, HuiYong; Su, Wenjing; Wang, Lu; Joelson, Andrew; Cercek, Andrea; Baselga, Jose; de Stanchina, Elisa; Saltz, Leonard; Berger, Michael F.; Solit, David B.; Rosen, Neal Share Save
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Tumors with class 3 BRAF mutants are sensitive to the inhibition of activated RAS Yao, Zhan; Yaeger, Rona; Rodrik-Outmezguine, Vanessa S.; Tao, Anthony; Torres, Neilawattie M.; Chang, Matthew T.; Drosten, Matthias; Zhao, Huiyong; Cecchi, Fabiola; Hembrough, Todd; Michels, Judith; Baumert, Herve; Miles, Linde; Campbell, Naomi M.; de Stanchina, Elisa; Solit, David B.; Barbacid, Mariano; Taylor, Barry S.; Rosen, Neal Share Save
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