Bechara Kachar - Publications, H-index & Citations

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Bechara Kachar

National Institutes of Health

74H-index

257Paper Count

1.9WCitation Count

Published Papers 74

Publication Date

Spontaneous calcium transients in hair cell stereocilia

Scientific Reports

IF3.9

2025-09-29

OAAI

Saman Hussain; Miloslav Sedlacek; Runjia Cui; Wendy Zhang-Hooks; Dwight E. Bergles; Jung-Bum Shin; Katie S. Kindt; Bechara Kachar

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Hemifusomes and interacting proteolipid nanodroplets mediate multi-vesicular body formation

NATURE COMMUNICATIONS

IF15.7

2025-05-17

OAAI

Tavakoli, Amirrasoul; Hu, Shiqiong; Ebrahim, Seham; Kachar, Bechara

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Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system

SCIENTIFIC REPORTS

IF3.9

2022-08-12

OAAI

Ballesteros, Angela; Yadav, Manoj; Cui, Runjia; Kurima, Kiyoto; Kachar, Bechara

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Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction

SCIENCE ADVANCES

IF12.5

2022-04-08

OAAI

Giffen, Kimberlee P.; Li, Yi; Liu, Huizhan; Zhao, Xiao-Chang; Zhang, Chang-Jun; Shen, Ren-Juan; Wang, Tianying; Janesick, Amanda; Chen, Bo-Bei; Gong, Shu-Sheng; Kachar, Bechara; Jin, Zi-Bing; He, David Z.

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T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2021-09-01

OAAI

Marchelletta, Ronald R.; Krishnan, Moorthy; Spalinger, Marianne R.; Placone, Taylaur W.; Alvarez, Rocio; Sayoc-Becerra, Anica; Canale, Vinicius; Shawki, Ali; Park, Young Su; Bernts, Lucas H. P.; Myers, Stephen; Tremblay, Michel L.; Barrett, Kim E.; Krystofiak, Evan; Kachar, Bechara; McGovern, Dermot P. B.; Weber, Christopher R.; Hanson, Elaine M.; Eckmann, Lars; McCole, Declan F.

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Myosin-VIIa is expressed in multiple isoforms and essential for tensioning the hair cell mechanotransduction complex

NATURE COMMUNICATIONS

IF15.7

2020-04-29

OAAI

Li, Sihan; Mecca, Andrew; Kim, Jeewoo; Caprara, Giusy A.; Wagner, Elizabeth L.; Du, Ting-Ting; Petrov, Leonid; Xu, Wenhao; Cui, Runjia; Rebustini, Ivan T.; Kachar, Bechara; Peng, Anthony W.; Shin, Jung-Bum

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Nanoarchitecture and dynamics of the mouse enteric glycocalyx examined by freeze-etching electron tomography and intravital microscopy

COMMUNICATIONS BIOLOGY

IF5.1

2020-01-07

OAAI

Sun, Willy W.; Krystofiak, Evan S.; Leo-Macias, Alejandra; Cui, Runjia; Sesso, Antonio; Weigert, Roberto; Ebrahim, Seham; Kachar, Bechara

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Moving Encounters: Actin Treadmilling in the Brush Border

DEVELOPMENTAL CELL

IF8.7

2019-09-01

OAAI

Kachar, Bechara

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Dynamic polyhedral actomyosin lattices remodel micron-scale curved membranes during exocytosis in live mice

NATURE CELL BIOLOGY

IF19.1

2019-07-29

OAAI

Ebrahim, Seham; Chen, Desu; Weiss, Max; Malec, Lenka; Ng, Yeap; Rebustini, Ivan; Krystofiak, Evan; Hu, Longhua; Liu, Jian; Masedunskas, Andrius; Hardeman, Edna; Gunning, Peter; Kachar, Bechara; Weigert, Roberto

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Carbon replicas reveal double stranded structure of tight junctions in phase-contrast electron microscopy

COMMUNICATIONS BIOLOGY

IF5.1

2019-03-12

OAAI

Krystofiak, Evan S.; Heymann, J. Bernard; Kachar, Bechara

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LMO7 deficiency reveals the significance of the cuticular plate for hearing function

NATURE COMMUNICATIONS

IF15.7

2019-03-08

OAAI

Du, Ting-Ting; Dewey, James B.; Wagner, Elizabeth L.; Cui, Runjia; Heo, Jinho; Park, Jeong-Jin; Francis, Shimon P.; Perez-Reyes, Edward; Guillot, Stacey J.; Sherman, Nicholas E.; Xu, Wenhao; Oghalai, John S.; Kachar, Bechara; Shin, Jung-Bum

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Prestin Contributes to Membrane Compartmentalization and Is Required for Normal Innervation o Outer Hair Cells

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2018-07-20

OAAI

Takahashi, Satoe; Sun, Willy; Zhou, Yingjie; Homma, Kazuaki; Kachar, Bechara; Cheatham, Mary Ann; Zheng, Jing

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Characterization of a novel MYO3A missense mutation associated with a dominant form of late onset hearing loss

SCIENTIFIC REPORTS

IF3.9

2018-06-07

OAAI

Dantas, Vitor G. L.; Raval, Manmeet H.; Ballesteros, Angela; Cui, Runjia; Gunther, Laura K.; Yamamoto, Guilherme L.; Alves, Leandro Ucela; Bueno, Andre Silva; Lezirovitz, Karina; Pirana, Sulene; Mendes, Beatriz C. A.; Yengo, Christopher M.; Kachar, Bechara; Mingroni-Netto, Regina C.

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Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea

NATURE COMMUNICATIONS

IF15.7

2018-06-05

OAAI

Beurg, Maryline; Cui, Runjia; Goldring, Adam C.; Ebrahim, Seham; Fettiplace, Robert; Kachar, Bechara

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Multiple claudin-claudin cis interfaces are required for tight junction strand formation and inherent flexibility

COMMUNICATIONS BIOLOGY

IF5.1

2018-05-17

OAAI

Zhao, Jun; Krystofiak, Evan S.; Ballesteros, Angela; Cui, Runjia; Van Itallie, Christina M.; Anderson, James M.; Fenollar-Ferrer, Cristina; Kachar, Bechara

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The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse

ELIFE

IF0

2018-01-12

OAAI

Becker, Lars; Schnee, Michael E.; Niwa, Mamiko; Sun, Willy; Maxeiner, Stephan; Talaei, Sara; Kachar, Bechara; Rutherford, Mark A.; Ricci, Anthony J.

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Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like (vol 7, 10833, 2016)

NATURE COMMUNICATIONS

IF15.7

2017-08-14

OAAI

Ebrahim, Seham; Avenarius, Matthew R.; Grati, M'hamed; Krey, Jocelyn F.; Windsor, Alanna M.; Sousa, Aurea D.; Ballesteros, Angela; Cui, Runjia; Millis, Bryan A.; Salles, Felipe T.; Baird, Michelle A.; Davidson, Michael W.; Jones, Sherri M.; Choi, Dongseok; Dong, Lijin; Raval, Manmeet H.; Yengo, Christopher M.; Barr-Gillespie, Peter G.; Kachar, Bechara

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Maturation arrest in early postnatal sensory receptors by deletion of the miR-183/96/182 cluster in mouse

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-05-08

OAAI

Fan, Jianguo; Jia, Li; Li, Yan; Ebrahim, Seham; May-Simera, Helen; Wood, Alynda; Morell, Robert J.; Liu, Pinghu; Lei, Jingqi; Kachar, Bechara; Belluscio, Leonardo; Qian, Haohua; Li, Tiansen; Li, Wei; Wistow, Graeme; Dong, Lijin

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Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid

JOURNAL OF CELL BIOLOGY

IF6.4

2016-11-03

OAAI

Krey, Jocelyn F.; Krystofiak, Evan S.; Dumont, Rachel A.; Vijayakumar, Sarath; Choi, Dongseok; Rivero, Francisco; Kachar, Bechara; Jones, Sherri M.; Barr-Gillespie, Peter G.

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Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-10-01

OAAI

Raval, Manmeet H.; Quintero, Omar A.; Weck, Meredith L.; Unrath, William C.; Gallagher, James W.; Cui, Runjia; Kachar, Bechara; Tyska, Matthew J.; Yengo, Christopher M.

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Research Directions