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D

David P. Fairlie

centre for chemistry and drug discovery institute for molecular bioscience the university of queensland

98H-index
719Paper Count
3.8WCitation Count
Published Papers 324
Publication Date
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Downsizing Electrophilic MAX‐Derived Helical Zipper Peptides to Covalently Bind and Degrade Oncogenic MYC
errAngewandte Chemie-International Edition
IF16.9
err2026-10-19
err0
PREAI
errAline Dantas de Araujo; Lei Luo; Mahan Azad; Miao Yu; Jody M. Mason; Junxian Lim; Timothy A. Hill; David P. Fairlie
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errSave
Specific targeting of MR1-antigen complexes using nanobodies
errScience Immunology
IF16.3
err2026-09-25
err0
PREAI
errHisham S. Hussain; Samuel J. Redmond; Wael Awad; Calvin Xu; Caroline Soliman; Huimeng Wang; Yuyang Zhang; Lisa Ciacchi; Alexis P. Gonzalez; Jeffrey Y. W. Mak; David P. Fairlie; James McCluskey; Alexandra J. Corbett; Adam P. Uldrich; Jamie Rossjohn; Dale I. Godfrey; Hui-Fern Koay; Nicholas A. Gherardin
errShare
errSave
The MHC-I related protein 1 MR1 can bind host purine catabolites
errJournal of Biological Chemistry
IF3.9
err2026-09-01
err0
PREAI
errAbdelaal, Mohamed R.; Lim, Xin Yi; Mak, Jeffrey Y. W.; Fairlie, David P.; McCluskey, James; Corbett, Alexandra J.; Gherardin, Nicholas A.; Awad, Wael; Rossjohn, Jamie
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errSave
Myeloid HDAC7 drives liver inflammation and systemic glucose dysregulation during diet-induced obesity
errClinical & Translational Immunology
IF3.8
err2026-05-29
err0
errOAAI
errYizhuo Wang; Divya Ramnath; Kaustav Das Gupta; P Prakrithi; Kavita Bisht; Gregory C Miller; Zherui Xiong; Yujun Wan; Ellen N Tejo; James EB Curson; Rishika Abrol; Sahar Keshvari; Kimberley S Gunther; Jordan D Atkinson; Zhixuan Loh; Jessica A Engel; Christian R Engwerda; Sabrina Sofia Burgener; Kate Schroder; David P Fairlie; Andrew D Clouston; Elizabeth E Powell; Katharine M Irvine; Mitchell A Sullivan; Jean-Pierre Lévesque; Quan Nguyen; Matthew J Sweet; Denuja Karunakaran
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errSave
Utility and Limitations of the Methyl Diaminobenzene-BODIPY Fluorescent Biosensor for Detecting Methylglyoxal in Cells
errACS Omega
IF4.3
err2026-05-28
err0
errOAAI
errRangsima Ponvattanaporn; Jeremy P. Le; Zhimo Li; Ryan J.D. Rivero; Jeffrey Y.W. Mak; David P. Fairlie; Hamish E.G. McWilliam; Abderrahman Hachani; Alexandra J. Corbett; Timothy Patton
errShare
errSave
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
errMedicinal Research Reviews
IF11.6
err2026-05-26
err0
errOAAI
errWisam A. Dawood; Jacinta R. Macdonald; Christian Anzenhofer; Tina S. Skinner-Adams; Robert C. Reid; Thomas Kurz; David P. Fairlie; Katherine T. Andrews
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errSave
Cytosolic delivery of bacterial metabolites by riboflavin transporters promotes MR1 antigen presentation and MAIT cell recognition
errimmunology & cell biology
IF0
err2026-05-06
err0
errOAAI
errSebastian Cruz-Gomez; Hui Jing Lim; Brunda Nijagal; Yuting Yang; Nicole Lau; Jeffrey YW Mak; David P Fairlie; Hayley Newton; Mariolina Salio; Jose A Villadangos; Hamish EG McWilliam
errShare
errSave
Experimental Evidence for a Metal-Related Function of a Cyanobactin
errAngewandte Chemie International Edition
IF16.9
err2026-05-02
err0
errOAAI
errPhilipp Baur; Timothy A. Hill; Kai-Chen Wu; Junxian Lim; Brett M. Paterson; Gunasekaran Velmurugan; Bernard M. Degnan; David P. Fairlie; Peter Comba
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errSave
Mitochondrial fission mediates an evolutionarily conserved antibacterial defense response
errScience Immunology
IF16.3
err2026-04-24
err0
PREAI
errRonan Kapetanovic; Syeda Farhana Afroz; James E. B. Curson; Ina Kirmes; Divya Ramnath; Stephan Nothjunge; Jinting Liu; Jordan D. Atkinson; Arnaud Ahier; Karoline D. Raven; Marta Bosch; Bernhard Keller; Grace M. E. P. Lawrence; Kaustav Das Gupta; Melanie R. Shakespear; Charles Ferguson; Claudia J. Stocks; Nilesh J. Bokil; Gabriele Matthias; Tam T. K. Nguyen; Zeinab G. Khalil; Robert C. Reid; Karl A. Hansford; Philip M. Hansbro; Matthew A. Cooper; Mark A. Schembri; Antje Blumenthal; Kate Schroder; David P. Fairlie; Albert Pol; Patrick Matthias; Robert G. Parton; Steven Zuryn; Matthew J. Sweet
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errSave
Restoration of Mucosa-Associated Invariant T-Cell Function in Healthcare-Associated Bacterial Infections Supports Recovery of Carbapenem Efficacy Against Resistant Bacteria Ex Vivo
errJournal of Infectious Diseases
IF4.5
err2026-04-01
err0
PREAI
errXue, Yiting; Karim, Asad Mustafa; Sia, Wan Rong; Han, Fei; Chan, Kai Lin; Chua, Nathalie Grace; Hadadi, Leila; Liu, Zhenyu; Mak, Jeffrey Y. W.; Fairlie, David P.; Wang, Lin-Fa; Sandberg, Johan K.; Kwa, Andrea Lay-Hoon; Leeansyah, Edwin
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errSave
The NF-κB transcription factor RelA directs mucosal-associated invariant T-cell development
errimmunology & cell biology
IF0
err2026-02-23
err0
errOAAI
errThomas S Fulford; Hui-Fern Koay; Raelene Grumont; Darryl N Johnson; Sebastian Scheer; Hendrik J Nel; Ranjeny Thomas; Jeffrey YW Mak; David P Fairlie; Charis E Teh; Daniel HD Gray; Vanessa L Bryant; Colby Zaph; Lorraine A O'Reilly; Steven Gerondakis; Dale I Godfrey
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errSave
Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation
errScience
IF45.8
err2026-01-15
err5
PREAI
errDeng, Jieru; Yan, Yuting; Zhang, Xiaoyue; Walsh, Calum J.; Montassier, Emmanuel; Sinha, Debajyoti; Wang, Huimeng; Mousavizadeh, Atieh; Ashayeripanah, Mitra; Mak, Jeffrey Y. W.; Koay, Hui-Fern; Poch, Tobias; Alexandre, Yannick O.; Mueller, Scott N.; Vasanthakumar, Ajithkumar; Stinear, Tim P.; Jameson, Vanta J.; Perez-Gonzalez, Alexis; Kingham, Jenny; Phan, Tri Giang; Potemkin, Nikita; Dryburgh, Lachlan; Schroeder, Jan; Fairlie, David P.; Mackay, Laura K.; Chen, Zhenjun; Cook, Laura; Hachani, Abderrahman; Corbett, Alexandra J.; Roquilly, Antoine; Villadangos, Jose A.; McWilliam, Hamish E. G.
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errSave
Histone deacetylase 7 mediates lipopolysaccharide-inducible mitochondrial fission in macrophages
errJOURNAL OF CELL SCIENCE
IF3.6
err2025-10-01
err0
errOAAI
errAbrol, Rishika; Afroz, Syeda Farhana; Curson, James E. B.; Raven, Karoline D.; Das Gupta, Kaustav; Gunther, Kimberley S.; Jones, Alun; Reid, Robert C.; Xiong, Zherui; Gunter, Jennifer H.; Engel, Jessica A.; Engwerda, Christian R.; Blumenthal, Antje; Fairlie, David P.; Parton, Robert G.; Zuryn, Steven; Kapetanovic, Ronan; Ramnath, Divya; Sweet, Matthew J.
errShare
errSave
A molecular basis underpinning TRBV28+ T cell receptor recognition of MR1-antigen
errJournal of Biological Chemistry
IF3.9
err2025-06-01
err0
errOAAI
errWael Awad; Nicholas A. Gherardin; Lisa Ciacchi; Andrew N. Keller; Ligong Liu; David P. Fairlie; James McCluskey; Dale I. Godfrey; Jamie Rossjohn
errShare
errSave
Herpes simplex virus type 1 impairs mucosal-associated invariant T cells
errMBIO
IF4.7
err2025-05-14
err0
errOAAI
errStern, Lauren; Emanuel, Zoe; Traves, Renee; Willis, Katherine; Purohit, Shivam K.; Samer, Carolyn; Mak, Jeffrey Y. W.; Fairlie, David P.; Tscharke, David C.; Corbett, Alexandra J.; Abendroth, Allison; Slobedman, Barry
errShare
errSave
Protease-activated receptor 2: A promising therapeutic target for women's cancers
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-01-01
err0
errOAAI
errShah, Himani; Fairlie, David P.; Lim, Junxian
errShare
errSave
MAIT cell plasticity enables functional adaptation that drives antibacterial immune protection
errSCIENCE IMMUNOLOGY
IF16.3
err2024-12-06
err0
PREAI
errWang, Huimeng; Souter, Michael N. T.; Moreira, Marcela de Lima; Li, Shihan; Zhou, Yuchen; Nelson, Adam G.; Yu, Jinhan; Meehan, Lucy J.; Meehan, Bronwyn S.; Eckle, Sidonia B. G.; Lee, Hyun Jae; Schroeder, Jan; Haque, Ashraful; Mak, Jeffrey Y. W.; Fairlie, David P.; Mccluskey, James; Wang, Zhongfang; Chen, Zhenjun; Corbett, Alexandra J.
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errSave
MR1 presents vitamin B6-related compounds for recognition by MR1-reactive T cells
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-11-26
err0
PREAI
errMcinerney, Mitchell P.; Awad, Wael; Souter, Michael N. T.; Kang, Yang; Wang, Carl J. H.; Poa, Kean Chan Yew; Abdelaal, Mohamed R.; Le, Ngoc H.; Shepherd, Chloe M.; Mcneice, Conor; Meehan, Lucy J.; Nelson, Adam G.; Raynes, Jeremy M.; Mak, Jeffrey Y. W.; Mccluskey, James; Chen, Zhenjun; Ang, Ching-Seng; Fairlie, David P.; Le Nours, Jerome; Illing, Patricia T.; Rossjohn, Jamie; Purcell, Anthony W.
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errSave
Selective regulation of IFN-γ and IL-4 co-producing unconventional T cells by purinergic signaling
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2024-11-19
err1
PREAI
errXu, Calvin; Obers, Andreas; Qin, Minyi; Brandli, Alice; Wong, Joelyn; Huang, Xin; Clatch, Allison; Fayed, Aly; Starkey, Graham; D'Costa, Rohit; Gordon, Claire L.; Mak, Jeffrey Y. W.; Fairlie, David P.; Beattie, Lynette; Mackay, Laura K.; Godfrey, Dale I.; Koay, Hui-Fern
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errSave
Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain
errBIOCHEMICAL JOURNAL
IF4.3
err2024-10-25
err0
PREAI
errWang, Yizhuo; Curson, James E. B.; Ramnath, Divya; Das Gupta, Kaustav; Reid, Robert C.; Karunakaran, Denuja; Fairlie, David P.; Sweet, Matthew J.
errShare
errSave

Research Directions

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Co-authors
Cooperation Journals
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Robert G. Parton
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Philip Hugenholtz
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Bruce D. Hammock
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