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Gregg L. Semenza

johns hopkins university

185H-index
682Paper Count
15.6WCitation Count
Published Papers 295
Publication Date
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HIF-1-mediated ISG20 expression promotes breast cancer stemness and immune evasion
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2025-12-12
err0
PREAI
errYang, Yongkang; Zuo, Qiaozhu; Ramu, Vijay; Talwar, Varen; Lyu, Yajing; Chen, Chelsey; Drehmer, Daiana; Huang, Tina Yi-Ting; Salman, Shaima; Dordai, Dominic; Wang, Yufeng; Datan, Emmanuel; Wicks, Elizabeth E.; Semenza, Gregg L.
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Retraction: Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling
errJournal of Biological Chemistry
IF3.9
err2025-07-01
err0
errOAAI
errKenji Kasuno; Satoshi Takabuchi; Kazuhiko Fukuda; Shinae Kizaka-Kondoh; Junji Yodoi; Takehiko Adachi; Gregg L. Semenza; Kiichi Hirota
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Retraction: Induction of Hypoxia-inducible Factor 1 Activity by Muscarinic Acetylcholine Receptor Signaling
errJournal of Biological Chemistry
IF3.9
err2025-07-01
err0
errOAAI
errKiichi Hirota; Ryo Fukuda; Satoshi Takabuchi; Shinae Kizaka-Kondoh; Takehiko Adachi; Kazuhiko Fukuda; Gregg L. Semenza
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errSave
Development of Small Molecule Inhibitors of Hypoxia-Inducible Factors for Cancer Therapy
errPharmacological Reviews
IF17.3
err2025-06-26
err0
PREAI
errGregg L. Semenza
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errSave
Broad and synergistic anti-tumor effects of small-molecule inhibitors of hypoxia inducible factors when paired with immune checkpoint blockade
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2024-12-09
err0
PREAI
errSalman, Shaima; Huang, Tina Y.; Hwang, Yousang; Kumar, Anmol; Dordai, Dominic; MacKerell, Alexander D., Jr.; Semenza, Gregg L.
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RETRACTION: Retraction: Collagen Prolyl Hydroxylases Are Essential for Breast Cancer Metastasis
errCANCER RESEARCH
IF16.6
err2024-09-04
err0
PREAI
errGilkes, Daniele M.; Chaturvedi, Pallavi; Bajpai, Saumendra; Wong, Carmen C.; Wei, Hong; Pitcairn, Stephen; Hubbi, Maimon E.; Wirtz, Denis; Semenza, Gregg L.
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RETRACTION: PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis
errCANCER RESEARCH
IF16.6
err2024-09-04
err0
PREAI
errSamanta, Debangshu; Park, Youngrok; Andrabi, Shaida A.; Shelton, Laura M.; Gilkes, Daniele M.; Semenza, Gregg L.
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Pharmacologic HIF stabilization activates costimulatory receptor expression to increase antitumor efficacy of adoptive T cell therapy
errSCIENCE ADVANCES
IF12.5
err2024-08-30
err0
errOAAI
errJackson III, Walter; Yang, Yongkang; Salman, Shaima; Dordai, Dominic; Lyu, Yajing; Datan, Emmanuel; Drehmer, Daiana; Huang, Tina Yi-Ting; Hwang, Yousang; Semenza, Gregg L.
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Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and activation of
errCELL REPORTS
IF6.9
err2024-04-01
err2
errOAAI
errLyu, Yajing; Yang, Yongkang; Talwar, Varen; Lu, Haiquan; Chen, Chelsey; Salman, Shaima; Wicks, Elizabeth E.; Huang, Tina Yi-Ting; Drehmer, Daiana; Wang, Yufeng; Zuo, Qiaozhu; Datan, Emmanuel; Jackson III, Walter; Dordai, Dominic; Wang, Ru; Semenza, Gregg L.
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Targeting intratumoral hypoxia to enhance anti-tumor immunity
errSEMINARS IN CANCER BIOLOGY
IF15.7
err2023-11-01
err15
errOAAI
errSemenza, Gregg L.
errShare
errSave
RETRACTION: Procollagen Lysyl Hydroxylase 2 Is Essential for Hypoxia-Induced Breast Cancer Metastasis (Retraction of Vol 11, Pg 456, 2013)
errMOLECULAR CANCER RESEARCH
IF4.7
err2023-10-02
err0
errOAAI
errGilkes, Daniele M.; Bajpai, Saumendra; Wong, Carmen C.; Chaturvedi, Pallavi; Hubbi, Maimon E.; Wirtz, Denis; Semenza, Gregg L.
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errSave
Mechanisms of Breast Cancer Stem Cell Specification and Self-Renewal Mediated by Hypoxia-Inducible Factor 1
errSTEM CELLS TRANSLATIONAL MEDICINE
IF4.9
err2023-09-28
err8
errOAAI
errSemenza, Gregg L.
errShare
errSave
Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts (Withdrawal of Vol 288, art no 10819, 2013)
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-09-01
err0
errOAAI
errGilkes, Daniele M.; Bajpai, Saumendra; Chaturvedi, Pallavi; Wirtz, Denis; Semenza, Gregg L.
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errSave
Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-07-03
err8
errOAAI
errZhang, Jing; Sharma, Deepti; Dinabandhu, Aumreetam; Sanchez, Jaron; Applewhite, Brooks; Jee, Kathleen; Deshpande, Monika; Flores-Bellver, Miguel; Hu, Ming-Wen; Guo, Chuanyu; Salman, Shaima; Hwang, Yousang; Anders, Nicole M.; Rudek, Michelle A.; Qian, Jiang; Canto-Soler, M. Valeria; Semenza, Gregg L.; Montaner, Silvia; Sodhi, Akrit
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On either side of homeostasis: EPAS1 gain- and loss-of- function mutations
errHAEMATOLOGICA
IF7.9
err2023-06-08
err0
errOAAI
errPrchal, Josef T.; Semenza, Gregg L.
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errSave
RETRACTION: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs (vol 31, pg 1757, 2012) (Retraction of Vol 31, Pg 1757, 2012)
errONCOGENE
IF7.3
err2023-05-23
err0
errOAAI
errZhang, H.; Wong, C. C. L.; Wei, H.; Gilkes, D. M.; Korangath, P.; Chaturvedi, P.; Schito, L.; Chen, J.; Krishnamachary, B.; Winnard, P. T.; Raman, V.; Zhen, L.; Mitzner, W. A.; Sukumar, S.; Semenza, G. L.
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errSave
HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1α (HIF-1α) synthesis:: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err1.3K
errOAAI
errLaughner, E; Taghavi, P; Chiles, K; Mahon, PC; Semenza, GL
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Hypoxia-inducible factor I and dysregulated c-myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err622
errOAAI
errKim, Jung-Whan; Gao, Ping; Liu, Yen-Chun; Semenza, Gregg L.; Dang, Chi V.
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Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis
errCELL REPORTS
IF6.9
err2023-03-01
err6
errOAAI
errZuo, Qiaozhu; Yang, Yongkang; Lyu, Yajing; Yang, Chen; Chen, Chelsey; Salman, Shaima; Huang, Tina Yi-Ting; Wicks, Elizabeth E.; Jackson, Walter, III; Datan, Emmanuel; Qin, Wenxin; Semenza, Gregg L.
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Regulation of Erythropoiesis by the Hypoxia-Inducible Factor Pathway: Effects of Genetic and Pharmacological Perturbations
errannual review of psychology
IF22.1
err2023-01-27
err35
errOAAI
errSemenza, Gregg L.
errShare
errSave

Research Directions

No research directions
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