Joost D. de Bruijn - Publications, H-index & Citations

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Joost D. de Bruijn

kuros biosciences bv

60H-index

237Paper Count

1.3WCitation Count

Published Papers 77

Publication Date

Mitochondrial OXPHOS integrates immunometabolic cascade for bone regeneration via coupled ATP production and ROS homeostasis

Redox Biology

IF11.9

2026-06-22

OAAI

Jingrong Chen; Ping He; Jiayi Gu; Jingqi Wu; Yuxiao Liu; Wei Lei; Tong-Chuan He; Liwen Zheng; Joost D. de Bruijn; Huipin Yuan; Hongmei Zhang; Mingzheng Li

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Humanized Bone Model Identifies BMP6 as a Multifunctional Regulator in Myeloma Bone Disease

Biomolecules 2025, Vol. 15, Page 1747

IF4.8

2025-12-18

OAAI

Jiaxian Wang; Thomas Baardemans; Ricardo de Matos Simoes; Willy Noort; Ruud W. J. Ruiter; Henk-Jan Prins; Susan E. van Hal-van Veen; Huipin Yuan; Joost D. de Bruijn; Anton C. M. Martens; Constantine S. Mitsiades; Sonja Zweegman; Maria Themeli; Richard W. J. Groen

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Apolipoprotein E as a potential regulator of osteoclast-osteoblast coupling in material-induced bone formation

Acta Biomaterialia

IF9.6

2025-05-29

PREAI

Yue Wang; Zhangling Nie; Huaze Liu; Joost D. de Bruijn; Huipin Yuan; Chongyun Bao

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Osteoclastogenesis-characterized osteoinductive biphasic calcium phosphate ceramic for bone regeneration in rabbit maxillary sinus lift

JOURNAL OF MATERIALS CHEMISTRY B

IF5.7

2025-01-01

PREAI

Lei, Wei; Wu, Yan; He, Ping; Wu, Jingqi; Chen, Jingrong; Liu, Yuxiao; Zhang, Hongmei; de Bruijn, Joost D.; Bao, Chongyun; Li, Yong; Ji, Ping

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The genetic background determines material-induced bone formation through the macrophage-osteoclast axis

BIOMATERIALS

IF12.9

2023-11-01

PREAI

Li, Mingzheng; Li, Dan; Jiang, Yucan; He, Ping; Li, Yeming; Wu, Yan; Lei, Wei; de Bruijn, Joost D.; Cannon, Richard D.; Mei, Li; Zhang, Hua; Ji, Ping; Zhang, Hongmei; Yuan, Huipin

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Specific Targeting of Multiple Myeloma by Dual Split-signaling Chimeric Antigen Receptor T cells Directed against CD38 and CD138

CLINICAL CANCER RESEARCH

IF10.2

2023-08-01

PREAI

van der Schans, Jort J.; Wang, Ziyu; van Arkel, Jennemiek; van Schaik, Thijs; Katsarou, Afroditi; Ruiter, Ruud; Baardemans, Thomas; Yuan, Huipin; de Bruijn, Joost; Zweegman, Sonja; van de Donk, Niels W. C. J.; Groen, Richard W. J.; Themeli, Maria; Mutis, Tuna

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Hypoxia Drives Material-Induced Heterotopic Bone Formation by Enhancing Osteoclastogenesis via M2/Lipid-Loaded Macrophage Axis

ADVANCED SCIENCE

IF14.1

2023-03-27

OAAI

Li, Dan; Jiang, Yucan; He, Ping; Li, Yeming; Wu, Yan; Lei, Wei; Liu, Nanxin; de Bruin, Joost D.; Zhang, Hua; Zhang, Hongmei; Ji, Ping; Yuan, Huipin; Li, Mingzheng

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Genesis of osteoclasts on calcium phosphate ceramics and their role in material-induced bone formation

ACTA BIOMATERIALIA

IF9.6

2023-02-01

PREAI

Nie, Zhangling; Hu, Zhiqiao; Guo, Xiaodong; Xiao, Yu; Liu, Xian; Bruijn, Joost D. de; Bao, Chongyun; Yuan, Huipin

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Exploration of CO2 capture from blast furnace gas using (semi)clathrates

CHEMICAL ENGINEERING RESEARCH & DESIGN

IF3.9

2022-11-01

OAAI

de Bruijn, J.; Essink, M. A. J.; Wolbers, J. H. T.; Ruitenbeek, M.; van den Berg, H.; Ham, A. G. J. van der

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Physico-Chemical Characteristics and Posterolateral Fusion Performance of Biphasic Calcium Phosphate with Submicron Needle-Shaped Surface Topography Combined with a Novel Polymer Binder

MATERIALS

IF3.2

2022-02-11

OAAI

Belluomo, Ruggero; Arriola-Alvarez, Inazio; Kucko, Nathan W.; Walsh, William R.; de Bruijn, Joost D.; Oliver, Rema A.; Wills, Dan; Crowley, James; Wang, Tian; Barrere-de Groot, Florence

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Combining a CAR and a chimeric costimulatory receptor enhances T cell sensitivity to low antigen density and promotes persistence

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-12-08

OAAI

Katsarou, Afroditi; Sjostrand, Maria; Naik, Jyoti; Mansilla-Soto, Jorge; Kefala, Dionysia; Kladis, Georgios; Nianias, Alexandros; Ruiter, Ruud; Poels, Renee; Sarkar, Irene; Patankar, Yash R.; Merino, Elena; Reijmers, Rogier M.; Frerichs, Kristine A.; Yuan, Huipin; de Bruijn, Joost; Stroopinsky, Dina; Avigan, David; van de Donk, Niels W. C. J.; Zweegman, Sonja; Mutis, Tuna; Sadelain, Michel; Groen, Richard W. J.; Themeli, Maria

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Serial cellular events in bone formation initiated by calcium phosphate ceramics

ACTA BIOMATERIALIA

IF9.6

2021-10-01

PREAI

Guo, Xiaodong; Li, Mingzheng; Qi, Wenting; Bai, Hetian; Nie, Zhangling; Hu, Zhiqiao; Xiao, Yu; de Bruijn, Joost D.; Bao, Chongyun; Yuan, Huipin

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CD38-specific Chimeric Antigen Receptor Expressing Natural Killer KHYG-1 Cells: A Proof of Concept for an Off the Shelf Therapy for Multiple Myeloma

HEMASPHERE

IF14.6

2021-07-01

OAAI

Stikvoort, Arwen; van der Schans, Jort; Sarkar, Subhashis; Poels, Renee; Ruiter, Ruud; Naik, Jyoti; Yuan, Huipin; de Bruijn, Joost D.; van de Donk, Niels W. C. J.; Zweegman, Sonja; Themeli, Maria; Groen, Richard; O'Dwyer, Michael; Mutis, Tuna

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Coupling between macrophage phenotype, angiogenesis and bone formation by calcium phosphates

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS

IF8.1

2021-03-01

OAAI

Duan, Rongquan; Zhang, Yang; van Dijk, Luuk; Barbieri, Davide; van den Beucken, Jeroen; Yuan, Huipin; de Bruijn, Joost

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Complete Tumor Regression by Liposomal Bortezomib in a Humanized Mouse Model of Multiple Myeloma

HEMASPHERE

IF14.6

2020-08-27

OAAI

Deshantri, Anil K.; Fens, Marcel H. A. M.; Ruiter, Ruud W. J.; Metselaar, Josbert M.; Storm, Gert; Mandhane, Sanjay N.; Graat, Gerard H. M.; Lentjes, Eef G. W.; Yuan, Huipin; de Bruijn, Joost D.; Mutis, Tuna; Martens, Anton C. M.; Groen, Richard W. J.; Schiffelers, Raymond M.

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Macrophage polarization plays roles in bone formation instructed by calcium phosphate ceramics

JOURNAL OF MATERIALS CHEMISTRY B

IF5.7

2020-01-01

OAAI

Li, Mingzheng; Guo, Xiaodong; Qi, Wenting; Wu, Zhenzhen; De Bruijn, Joost D.; Xiao, Yu; Bao, Chongyun; Yuan, Huipin

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Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone

JBMR PLUS

IF2.4

2019-11-22

OAAI

Westhrin, Marita; Holien, Toril; Zahoor, Muhammad; Moen, Siv Helen; Buene, Glenn; Stordal, Berit; Hella, Hanne; Yuan, Huipin; de Bruijn, Joost D.; Martens, Anton; Groen, Richard W. J.; Bosch, Fatima; Smith, Ulf; Sponaas, Anne-Marit; Sundan, Anders; Standal, Therese

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PARTIAL INHIBITION OF THE KEY GLYCOLYTIC ENZYME PFKFB3 IN MYELOID CELLS IMPACTS WHOLE-BODY IMMUNE CELL AND LIVER METABOLISM, BUT NOT ATHEROGENESIS.

ATHEROSCLEROSIS

IF5.7

2019-08-01

PREAI

De Bruijn, J.; van Kuijk, K.; Bijnen, M.; Gijbels, M.; Wouters, K.; Carmeliet, P.; Sluimer, J.

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Combined CD28 and 4-1BB Costimulation Potentiates Affinity-tuned Chimeric Antigen Receptor-engineered T Cells

CLINICAL CANCER RESEARCH

IF10.2

2019-07-01

133

OAAI

Drent, Esther; Poels, Renee; Ruiter, Ruud; van de Donk, Niels W. C. J.; Zweegman, Sonja; Yuan, Huipin; de Bruijn, Joost; Sadelain, Michel; Lokhorst, Henk M.; Groen, Richard W. J.; Mutis, Tuna; Themeli, Maria

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Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma

HAEMATOLOGICA

IF7.9

2019-05-23

OAAI

Holthof, Lisa C.; van der Horst, Hilma J.; van Hal-van Veen, Susan E.; Ruiter, Ruud W. J.; Li, Fengzhi; Buijze, Marijke; Andersen, Morten N.; Yuan, Huipin; de Bruijn, Joost; van de Donk, Niels W. C. J.; Lokhorst, Henk M.; Zweegman, Sonja; Groen, Richard W. J.; Mutis, Tuna

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Research Directions