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The UFMylation pathway is impaired in Alzheimer's disease Yan, Tingxiang; Heckman, Michael G.; Craver, Emily C.; Liu, Chia-Chen; Rawlinson, Bailey D.; Wang, Xue; Murray, Melissa E.; Dickson, Dennis W.; Ertekin-Taner, Nilufer; Lou, Zhenkun; Bu, Guojun; Springer, Wolfdieter; Fiesel, Fabienne C. Share Save
Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference Kloske, Courtney M.; Belloy, Michael E.; Blue, Elizabeth E.; Bowman, Gregory R.; Carrillo, Maria C.; Chen, Xiaoying; Chiba-Falek, Ornit; Davis, Albert A.; Di Paolo, Gilbert; Garretti, Francesca; Gate, David; Golden, Lesley R.; Heinecke, Jay W.; Herz, Joachim; Huang, Yadong; Iadecola, Costantino; Johnson, Lance A.; Kanekiyo, Takahisa; Karch, Celeste M.; Khvorova, Anastasia; Koppes-den Hertog, Sascha J.; Lamb, Bruce T.; Lawler, Paige E.; Guen, Yann Le; Litvinchuk, Alexandra; Liu, Chia-Chen; Mahinrad, Simin; Marcora, Edoardo; Marino, Claudia; Michaelson, Danny M.; Miller, Justin J.; Morganti, Josh M.; Narayan, Priyanka S.; Naslavsky, Michel S.; Oosthoek, Marlies; Ramachandran, Kapil V.; Ramakrishnan, Abhirami; Raulin, Ana-Caroline; Robert, Aiko; Saleh, Rasha N. M.; Sexton, Claire; Shah, Nilomi; Shue, Francis; Sible, Isabel J.; Soranno, Andrea; Strickland, Michael R.; Julia, T. C. W.; Thierry, Manon; Tsai, Li-Huei; Tuckey, Ryan A.; Ulrich, Jason D.; van der Kant, Rik; Wang, Na; Wellington, Cheryl L.; Weninger, Stacie C.; Yassine, Hussein N.; Zhao, Na; Bu, Guojun; Goate, Alison M.; Holtzman, David M. Share Save
Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer's disease Raulin, Ana-Caroline; Doss, Sydney V.; Heckman, Michael G.; Craver, Emily C.; Li, Zonghua; Ikezu, Tadafumi C.; Sekiya, Hiroaki; Liu, Chia-Chen; Martens, Yuka A.; Rosenberg, Cassandra L.; Kuchenbecker, Lindsey A.; Deture, Michael; Reichard, R. Ross; Nguyen, Aivi T.; Constantopoulos, Eleni; Larsen, Rachel A.; Kounaves, Emmaline K.; Murray, Melissa E.; Dickson, Dennis W.; Petersen, Ronald C.; Bu, Guojun; Kanekiyo, Takahisa Share Save
Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease Liu, Chia-Chen; Wang, Na; Chen, Yuanxin; Inoue, Yasuteru; Shue, Francis; Ren, Yingxue; Wang, Minghui; Qiao, Wenhui; Ikezu, Tadafumi C.; Li, Zonghua; Zhao, Jing; Martens, Yuka; Doss, Sydney V.; Rosenberg, Cassandra L.; Jeevaratnam, Suren; Jia, Lin; Raulin, Ana-Caroline; Qi, Fangfang; Zhu, Yiyang; Alnobani, Alla; Knight, Joshua; Chen, Yixing; Linares, Cynthia; Kurti, Aishe; Fryer, John D.; Zhang, Bin; Wu, Long-Jun; Kim, Betty Y. S.; Bu, Guojun Share Save
Upregulation of sFRP1 Is More Profound in Female than Male 5xFAD Mice and Positively Associated with Amyloid Pathology Macyczko, Jesse R.; Wang, Na; Lu, Wenyan; Jeevaratnam, Suren; Shue, Francis; Martens, Yuka; Liu, Chia-Chen; Kanekiyo, Takahisa; Bu, Guojun; Li, Yonghe Share Save
Sex specific molecular networks and key drivers of Alzheimer's disease Guo, Lei; Cao, Jiqing; Hou, Jianwei; Li, Yonghe; Huang, Min; Zhu, Li; Zhang, Larry; Lee, Yeji; Duarte, Mariana Lemos; Zhou, Xianxiao; Wang, Minghui; Liu, Chia-Chen; Martens, Yuka; Chao, Michael; Goate, Alison; Bu, Guojun; Haroutunian, Vahram; Cai, Dongming; Zhang, Bin Share Save
Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology (vol 18, 8, 2023) Qiao, Wenhui; Chen, Yixing; Zhong, Jun; Madden, Benjamin J.; Charlesworth, Cristine M.; Martens, Yuka A.; Liu, Chia-Chen; Knight, Joshua; Ikezu, Tadafumi C.; Aishe, Kurti; Zhu, Yiyang; Meneses, Axel; Rosenberg, Cassandra L.; Kuchenbecker, Lindsey A.; Vanmaele, Lucy K.; Li, Fuyao; Chen, Kai; Shue, Francis; Dacquel, Maxwell V.; Fryer, John; Pandey, Akhilesh; Zhao, Na; Bu, Guojun Share Save
LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4 Oue, Hiroshi; Yamazaki, Yu; Qiao, Wenhui; Yuanxin, Chen; Ren, Yingxue; Kurti, Aishe; Shue, Francis; Parsons, Tammee M.; Perkerson, Ralph B.; Kawatani, Keiji; Wang, Ni; Starling, Skylar C.; Roy, Bhaskar; Mosneag, Ioana-Emilia; Aikawa, Tomonori; Holm, Marie-Louise; Liu, Chia-Chen; Inoue, Yasuteru; Sullivan, Patrick M.; Asmann, Yan W.; Kim, Betty Y. S.; Bu, Guojun; Kanekiyo, Takahisa Share Save
Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology Qiao, Wenhui; Chen, Yixing; Zhong, Jun; Madden, Benjamin J.; Charlesworth, Cristine M.; Martens, Yuka A.; Liu, Chia-Chen; Knight, Joshua; Ikezu, Tadafumi C.; Aishe, Kurti; Zhu, Yiyang; Meneses, Axel; Rosenberg, Cassandra L.; Kuchenbecker, Lindsey A.; Vanmaele, Lucy K.; Li, Fuyao; Chen, Kai; Shue, Francis; Dacquel, Maxwell V.; Fryer, John; Pandey, Akhilesh; Zhao, Na; Bu, Guojun Share Save
Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer's disease related proteins Oatman, Stephanie R.; Reddy, Joseph S.; Quicksall, Zachary; Carrasquillo, Minerva M.; Wang, Xue; Liu, Chia-Chen; Yamazaki, Yu; Nguyen, Thuy T.; Malphrus, Kimberly; Heckman, Michael; Biswas, Kristi; Nho, Kwangsik; Baker, Matthew; Martens, Yuka A.; Zhao, Na; Kim, Jun Pyo; Risacher, Shannon L.; Rademakers, Rosa; Saykin, Andrew J.; DeTure, Michael; Murray, Melissa E.; Kanekiyo, Takahisa; Dickson, Dennis W.; Bu, Guojun; Allen, Mariet; Ertekin-Taner, Niluefer Share Save
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Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination Wang, Na; Wang, Minghui; Jeevaratnam, Suren; Rosenberg, Cassandra; Ikezu, Tadafumi C.; Shue, Francis; Doss, Sydney, V; Alnobani, Alla; Martens, Yuka A.; Wren, Melissa; Asmann, Yan W.; Zhang, Bin; Bu, Guojun; Liu, Chia-Chen Share Save
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Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia Zhao, Na; Qiao, Wenhui; Li, Fuyao; Ren, Yingxue; Zheng, Jiaying; Martens, Yuka A.; Wang, Xusheng; Li, Ling; Liu, Chia-Chen; Chen, Kai; Zhu, Yiyang; Ikezu, Tadafumi C.; Li, Zonghua; Meneses, Axel D.; Jin, Yunjung; Knight, Joshua A.; Chen, Yixing; Bastea, Ligia; Linares, Cynthia; Sonustun, Berkiye; Job, Lucy; Smith, Madeleine L.; Xie, Manling; Liu, Yong U.; Umpierre, Anthony D.; Haruwaka, Koichiro; Quicksall, Zachary S.; Storz, Peter; Asmann, Yan W.; Wu, Long-Jun; Bu, Guojun Share Save
LRP1 is a neuronal receptor for α-synuclein uptake and spread Chen, Kai; Martens, Yuka A.; Meneses, Axel; Ryu, Daniel H.; Lu, Wenyan; Raulin, Ana Caroline; Li, Fuyao; Zhao, Jing; Chen, Yixing; Jin, Yunjung; Linares, Cynthia; Goodwin, Marshall; Li, Yonghe; Liu, Chia-Chen; Kanekiyo, Takahisa; Holtzman, David M.; Golde, Todd E.; Bu, Guojun; Zhao, Na Share Save
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