Not logged in Structure-guided discovery of a small molecule inhibitor of SARS-CoV-2 main protease with potent in vitro and in vivo antiviral activities Yuan, Shuofeng; Wang, Juan; Sang, Xiaohong; Xie, Yubin; Feng, Yong; Poon, Vincent Kwok-Man; Chan, Chris Chung-Sing; Tsang, Jessica Oi-Ling; Chik, Kenn Ka-Heng; Zhou, Jiao; Xu, Yan; Han, Pu; Zheng, Wenyan; Fu, Lifeng; Huang, Lina Sirui Mihara; Wu, Meixian; An, Jing; Yuen, Kwok-Yung; Qi, Jianxun; Huang, Ziwei; Chan, Jasper Fuk-Woo Share Save
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Discovery of a potent covalent inhibitor that unusually distorts the catalytic dyad of SARS-CoV-2 main protease Wang, Juan; Sang, Xiaohong; Zheng, Wenyan; Chan, Jasper Fuk-Woo; Zhou, Jiao; Xu, Yan; Han, Pu; Feng, Yong; Fu, Lifeng; Tsang, Jessica Oi-Ling; Yuan, Shuofeng; Ciechanover, Aaron; An, Jing; Yuen, Kwok-Yung; Qi, Jianxun; Huang, Ziwei Share Save
Two noncompeting human neutralizing antibodies targeting MPXV B6 show protective effects against orthopoxvirus infections Zhao, Runchu; Wu, Lili; Sun, Junqing; Liu, Dezhi; Han, Pu; Gao, Yue; Zhang, Yi; Xu, Yanli; Qu, Xiao; Wang, Han; Chai, Yan; Chen, Zhihai; Gao, George F.; Wang, Qihui Share Save
Molecular basis of hippopotamus ACE2 binding to SARS-CoV-2 Yang, Ruirui; Han, Pu; Han, Pengcheng; Li, Dedong; Zhao, Runchu; Niu, Sheng; Liu, Kefang; Li, Shihua; Tian, Wen-Xia; Gao, George Fu Share Save
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Rational design of a 'two-in-one' immunogen DAM drives potent immune response against mpox virus (Jan, 10.1038/s41590-023-01715-7, 2024) Wang, Han; Yin, Peng; Zheng, Tingting; Qin, Lanju; Li, Shihua; Han, Pu; Qu, Xiao; Wen, Jun; Ding, Haoyi; Wu, Jiahao; Kong, Tianxiang; Gao, Zhengrong; Hu, Songtao; Zhao, Xin; Cao, Xiangyu; Fang, Min; Qi, Jianxun; Xi, Jianzhong Jeff; Duan, Kai; Yang, Xiaoming; Zhang, Zhuobing; Wang, Qihui; Tan, Wenjie; Gao, George Fu Share Save
Rational design of a 'two-in-one' immunogen DAM drives potent immune response against monkeypox virus Wang, Han; Yin, Peng; Zheng, Tingting; Qin, Lanju; Li, Shihua; Han, Pu; Qu, Xiao; Wen, Jun; Ding, Haoyi; Wu, Jiahao; Kong, Tianxiang; Gao, Zhengrong; Hu, Songtao; Zhao, Xin; Cao, Xiangyu; Fang, Min; Qi, Jianxun; Xi, Jianzhong Jeff; Duan, Kai; Yang, Xiaoming; Zhang, Zhuobing; Wang, Qihui; Tan, Wenjie; Gao, George Fu Share Save
Defining a de novo non- RBM antibody as RBD-8 and its synergistic rescue of immune- evaded antibodies to neutralize Omicron SARS- CoV-2 Rao, Xia; Zhao, Runchu; Tong, Zhou; Guo, Shuxin; Peng, Weiyu; Liu, Kefang; Li, Shihua; Wu, Lili; Tong, Jianyu; Chai, Yan; Han, Pu; Wang, Feiran; Jia, Peng; Li, Zhaohui; Zhao, Xin; Li, Dedong; Zhang, Rong; Zhang, Xue; Zou, Weiwei; Li, Weiwei; Wang, Qihui; Gao, George Fu; Wu, Yan; Dai, Lianpan; Gao, Feng Share Save
Structural basis of white-tailed deer, Odocoileus virginianus, ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity Han, Pu; Meng, Yumin; Zhang, Di; Xu, Zepeng; Li, Zhiyuan; Pan, Xiaoqian; Zhao, Zhennan; Li, Linjie; Tang, Lingfeng; Qi, Jianxun; Liu, Kefang; Gao, George F. Share Save
Broad protective RBD heterotrimer vaccines neutralize SARS-CoV-2 including Omicron sub-variants XBB/BQ.1.1/BF.7 Zhang, Yanfang; Kang, Xinrui; Liu, Sheng; Han, Pu; Lei, Wenwen; Xu, Ke; Xu, Zepeng; Gao, Zhengrong; Zhou, Xuemei; An, Yaling; Han, Yuxuan; Liu, Kefang; Zhao, Xin; Dai, Lianpan; Wang, Peiyi; Wu, Guizhen; Qi, Jianxun; Xu, Kun; Gao, George F. Share Save
Rational design of an influenza-COVID-19 chimeric protective vaccine with HA-stalk and S-RBD Li, Yulei; Liu, Peipei; Hao, Tianjiao; Liu, Sheng; Wang, Xi; Xie, Yufeng; Xu, Ke; Lei, Wenwen; Zhang, Cheng; Han, Pu; Li, Ying; Jin, Xiyue; Huan, Yu; Lu, Yafei; Zhang, Rong; Li, Xiaoyan; Zhao, Xin; Xu, Kun; Liao, Pu; Lu, Xuancheng; Bi, Yuhai; Song, Hao; Wu, Guizhen; Zhu, Baoli; Gao, George F. Share Save
Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs Hu, Yu; Liu, Kefang; Han, Pu; Xu, Zepeng; Zheng, Anqi; Pan, Xiaoqian; Jia, Yunfei; Su, Chao; Tang, Lingfeng; Wu, Lili; Bai, Bin; Zhao, Xin; Tian, Di; Chen, Zhihai; Qi, Jianxun; Wang, Qihui; Gao, George F. Share Save
Cross-species recognition of bat coronavirus RsYN04 and cross-reaction of SARS-CoV-2 antibodies against the virus Zhao, Runchu; Niu, Sheng; Han, Pu; Gao, Yue; Liu, Dezhi; Luo, Chunliang; Liu, Honghui; Liu, Bo; Xu, Yanli; Qi, Jianxun; Chen, Zhihai; Shi, Weifeng; Wu, Lili; Gao, George F.; Wang, Qihui Share Save
Cross-reaction of current available SARS-CoV-2 MAbs against the pangolin-origin coronavirus GX/P2V/2017 Jia, Yunfei; Niu, Sheng; Hu, Yu; Chai, Yan; Zheng, Anqi; Su, Chao; Wu, Lili; Han, Pengcheng; Han, Pu; Lu, Dan; Liu, Zhimin; Yan, Xinxi; Tian, Di; Chen, Zhihai; Qi, Jianxu; Tian, Wen-xia; Wang, Qihui; Gao, George Fu Share Save
Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18 Chen, Xiangpeng; Qu, Xiao; Liu, Congcong; Zhang, Yong; Zhang, Guigen; Han, Pu; Duan, Yali; Li, Qi; Wang, Liang; Ruan, Wenjing; Wang, Peiyi; Wei, Wensheng; Gao, George F.; Zhao, Xin; Xie, Zhengde Share Save
Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape Zhao, Zhennan; Zhou, Jingya; Tian, Mingxiong; Huang, Min; Liu, Sheng; Xie, Yufeng; Han, Pu; Bai, Chongzhi; Han, Pengcheng; Zheng, Anqi; Fu, Lutang; Gao, Yuanzhu; Peng, Qi; Li, Ying; Chai, Yan; Zhang, Zengyuan; Zhao, Xin; Song, Hao; Qi, Jianxun; Wang, Qihui; Wang, Peiyi; Gao, George F. Share Save
Atlas of currently available human neutralizing antibodies against SARS-CoV-2 and escape by Omicron sub-variants BA.1/BA.1.1/BA.2/BA.3 Huang, Min; Wu, Lili; Zheng, Anqi; Xie, Yufeng; He, Qingwen; Rong, Xiaoyu; Han, Pu; Du, Pei; Han, Pengcheng; Zhang, Zengyuan; Zhao, Runchu; Jia, Yunfei; Li, Linjie; Bai, Bin; Hu, Ziliang; Hu, Shixiong; Niu, Sheng; Hu, Yu; Liu, Honghui; Liu, Bo; Cui, Kaige; Li, Weiwei; Zhao, Xin; Liu, Kefang; Qi, Jianxun; Wang, Qihui; Gao, George Fu Share Save
Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s Li, Linjie; Han, Pu; Huang, Baihan; Xie, Yufeng; Li, Weiwei; Zhang, Di; Han, Pengcheng; Xu, Zepeng; Bai, Bin; Zhou, Jingya; Kang, Xinrui; Li, Xiaomei; Zheng, Anqi; Zhang, Rong; Qiao, Shitong; Zhao, Xin; Qi, Jianxun; Wang, Qihui; Liu, Kefang; Gao, George Fu Share Save
Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals Li, Shihua; Yang, Ruirui; Zhang, Di; Han, Pu; Xu, Zepeng; Chen, Qian; Zhao, Runchu; Zhao, Xin; Qu, Xiao; Zheng, Anqi; Wang, Liang; Li, Linjie; Hu, Yu; Zhang, Rong; Su, Chao; Niu, Sheng; Zhang, Yanfang; Qi, Jianxun; Liu, Kefang; Wang, Qihui; Gao, George F. Share Save
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