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SaveShare Save Targeting EphA2 in Bladder Cancer Using a Novel Antibody-Directed Nanotherapeutic
Kamoun, Walid; Swindell, Elden; Pien, Christine; Luus, Lia; Cain, Jason; Pham, Minh; Kandela, Irawati; Huang, Zhaohua Richard; Tipparaju, Suresh K.; Koshkaryev, Alexander; Askoxylakis, Vasileios; Kirpotin, Dmitri B.; Bloom, Troy; Mino-Kenudson, Mari; Marks, James D.; Zalutskaya, Alena; Bshara, Wiam; Morrison, Carl; Drummond, Daryl C. Share Save Share Save Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse modelsKamoun, Walid S.; Kirpotin, Dmitri B.; Huang, Zhaohua Richard; Tipparaju, Suresh K.; Noble, Charles O.; Hayes, Mark E.; Luus, Lia; Koshkaryev, Alexander; Kim, Jaeyeon; Olivier, Ken; Kornaga, Tad; Oyama, Shinji; Askoxylakis, Vasileios; Pien, Christine; Kuesters, Geoffrey; Dumont, Nancy; Lugovskoy, Alexey A.; Schihl, Sarah A.; Wilton, John H.; Geddie, Melissa L.; Suchy, James; Grabow, Stephanie; Kohli, Neeraj; Reynolds, C. Patrick; Blaydes, Rachel; Zhou, Yu; Sawyer, Andrew J.; Marks, James D.; Drummond, Daryl C. Share Save Targeting EphA2 in bladder cancer using a novel antibody-directed nanotherapeuticKamoun, Walid; Swindell, Elden; Pien, Christine; Luus, Lia; Cain, Jason; Kandela, Irawati; Huang, Richard; Tipparaju, Suresh; Kirpotin, Dmitri; Bshara, Wiam; Askoxylakis, Vasileios; Morrison, Carl; Drummond, Daryl Share Save Companion Diagnostic 64Cu-Liposome Positron Emission Tomography Enables Characterization of Drug Delivery to Tumors and Predicts Response to Cancer NanomedicinesLee, Helen; Gaddy, Daniel; Ventura, Manuela; Bernards, Nicholas; de Souza, Raquel; Kirpotin, Dmitri; Wickham, Thomas; Fitzgerald, Jonathan; Zheng, Jinzi; Hendriks, Bart S. Share Save 64Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response in Patients with Metastatic Breast CancerLee, Helen; Shields, Anthony F.; Siegel, Barry A.; Miller, Kathy D.; Krop, Ian; Ma, Cynthia X.; LoRusso, Patricia M.; Munster, Pamela N.; Campbell, Karen; Gaddy, Daniel F.; Leonard, Shannon C.; Geretti, Elena; Blocker, Stephanie J.; Kirpotin, Dmitri B.; Moyo, Victor; Wickham, Thomas J.; Hendriks, Bart S. Share Save Mechanisms of synergy of carboplatin and an EphA2-targeted docetaxel antibody-directed nanotherapeuticKamoun, Walid S.; Sawyer, Andrew J.; Pien, Christine; Koshkaryev, Alexander; Luus, Lia; Merrigan, Samantha; Sun, Gang; Kozin, Sergey; Huang, Zhaohua Richard; Tipparaju, Suresh K.; Kirpotin, Dmitri B.; Xu, Hannah; Askoxylakis, Vasileios; Reynolds, Patrick C.; Drummond, Daryl C. Share Save Share Save Improving the developability of an anti-EphA2 single-chain variable fragment for nanoparticle targetingGeddie, Melissa L.; Kohli, Neeraj; Kirpotin, Dmitri B.; Razlog, Maja; Jiao, Yang; Kornaga, Tad; Rennard, Rachel; Xu, Lihui; Schoerberl, Birgit; Marks, James D.; Drummond, Daryl C.; Lugovskoy, Alexey A. Share Save Activity of an EphA2-targeted docetaxel nanoliposome in pancreatic patient-derived models as monotherapy and in combination with gemcitabineDrummond, Daryl C.; Straubinger, Ninfa L.; Chaudhuri, Tista Roy; Moser, Michael; Kamoun, Walid S.; Luus, Lia; Huang, Zhaohua Richard; Tipparaju, Suresh; Gillard, Bryan; Morrison, Carl; Repasky, Elizabeth; Kirpotin, Dmitri B.; Straubinger, Robert M. Share Save Nanoliposomal targeting of ephrin receptor A2 (EphA2): Preclinical in vitro and in vivo rationaleKamoun, Walid S.; Luus, Lia; Pien, Christine; Kornaga, Tad; Oyama, Shinji; Huang, Zhaohua Richard; Tipparaju, Suresh; Kirpotin, Dmitri B.; Marks, James D.; Koshkaryev, Alexander; Geddie, Melissa; Xu, Lihui; Lugovosky, Alexey; Drummond, Daryl C. Share Save Nanoliposomal targeting of Ephrin receptor A2 (EphA2): Clinical translationKamoun, Walid S.; Oyama, Shinji; Kornaga, Tad; Feng, Theresa; Luus, Lia; Pham, Minh T.; Kirpotin, Dmitri B.; Marks, James D.; Geddie, Melissa; Xu, Lihui; Lugovskoy, Alexey A.; Murphy, Monica; Morrisson, Carl; Drummond, Daryl C. Share Save MM-310, a novel EphA2-targeted docetaxel nanoliposomeKirpotin, Dmitri B.; Tipparaju, Suresh; Huang, Zhaohua Richard; Kamoun, VValid S.; Pien, Christine; Kornaga, Tad; Oyama, Shinji; Olivier, Ken; Marks, James D.; Koshkaryev, Alexander; Schihl, Sarah S.; Fetterly, Gerald; Schoeberl, Birgit; Noble, Charles; Hayes, Mark; Drummond, Daryl C. Share Save Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticleZhang, Kathy; Geddie, Melissa L.; Kohli, Neeraj; Kornaga, Tad; Kirpotin, Dmitri B.; Jiao, Yang; Rennard, Rachel; Drummond, Daryl C.; Nielsen, Ulrik B.; Xu, Lihui; Lugovskoy, Alexey A. Share Save Evaluating the pharmacodynamics and pharmacokinetic effects of MM-398, a nanoliposomal irinotecan (nal-IRI) in subcutaneous xenograft tumor models of human squamous cell carcinoma and small cell lung cancersChan, Daniel C.; Kalra, Ashish; Zhang, Zhiyong; Paz, Nancy; Kirpotin, Dmitri; Drummond, Daryl; Nielsen, Ulrik; Bunn, Paul A.; Fitzgerald, Jonathan Share Save The tumor microenvironment modulates the delivery and activation of liposomal encapsulated irinotecan, MM-398.Kalra, Ashish; Kim, Jaeyeon; Klinz, Stephan; Paz, Nancy; Reutt, Joseph; Drummond, Daryl; Kirpotin, Dmitri; Moyo, Victor; Bayever, Eliel; Laivins, Peter; Niyikiza, Clet; Nielsen, Ulrik; Fitzgerald, Jonathan Share Save Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenograftsChen, Pin-Yuan; Ozawa, Tomoko; Drummond, Daryl C.; Kalra, Ashish; Fitzgerald, Jonathan B.; Kirpotin, Dmitri B.; Wei, Kuo-Chen; Butowski, Nicholas; Prados, Michael D.; Berger, Mitchel S.; Forsayeth, John R.; Bankiewicz, Krystof; James, C. David Share Save A novel 64Cu-liposomal PET agent (MM-DX-929) predicts response to liposomal chemotherapeutics in preclinical breast cancer modelsLee, H.; Zheng, J.; Gaddy, D.; Kirpotin, D.; Dunne, M.; Drummond, D.; Allen, C.; Jaffray, D.; Hendriks, B.; Wickham, T. Share Save 
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