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PARAPROGRESSION DEFINES A DAMAGE RESPONSE FROM SYSTEMIC MRNA IMMUNOTHERAPY IN MALIGNANT GLIOMA Moor, Rachel; Weidert, Frances; Von Roemeling, Christina; Thomas, Nagheme; Aghaee, Mahya; Zhang, Dingpeng; Kline, Cassie; Prados, Michael; Mueller, Sabine; Rahman, Maryam; Castillo, Paul; Ghiaseddin, Ashley; Carrera-Justiz, Sheila; Mitchell, Duane; Mendez-Gomez, Hector; Ligon, John; Sayour, Elias Share Save
PNOC025: A phase 1 study assessing the safety and tolerability of magrolimab in children and adults with recurrent or progressive malignant brain tumors Whipple, Nicholas; Molinaro, Annette; Reddy, Alyssa; Jaeger-Krause, Marie; Iv, Michael; Villanueva-Meyer, Javier; Lupo, Janine; Cooney, Tabitha; Raber, Shannon; Hoffman, Carly; Jensen, Jessica; Prados, Michael; Gartrell, Robyn; Kline, Cassie; Cheshier, Samuel; Mueller, Sabine; Colman, Howard Share Save
Genetic ancestry superpopulations show distinct prevalence and outcomes across pediatric central nervous system tumors from the Pediatric Brain Tumor Atlas and Pediatric Neuro-Oncology Consortium Corbett, Ryan J.; Gullickson, Cricket C.; Geng, Zhuangzhuang; Brown, Miguel A.; Zhang, Bo; Zhong, Chuwei; Van Kuren, Nicholas; Chroni, Antonia; Blackden, Christopher; Naqvi, Ammar S.; Plisiewicz, Alexa; Mchugh, Sean; Drake, Emmett; Lehmann, Kaitlin; Davidson, Tom B.; Prados, Michael; Storm, Phillip B.; Resnick, Adam C.; Waanders, Angela J.; Waszak, Sebastian M.; Mueller, Sabine; Rokita, Jo Lynne; Kline, Cassie Share Save
PNOC009: Convection-enhanced delivery of liposomal irinotecan in patients with newly diagnosed diffuse intrinsic pontine glioma Mueller, Sabine; Kline, Cassie; Lu, Alex Y.; Hoogendijk, Raoull; Wembacher-Schroeder, Eva; Banerjee, Anuradha; Reddy, Alyssa T.; Raber, Shannon; Hoffman, Carly; Stoller, Schuyler; Prados, Michael; Molinaro, Annette; Gupta, Nalin Share Save
DECREASED GROWTH VELOCITY IN A PHASE 1 TRIAL (PNOC014) OF TOVORAFENIB IN PATIENTS WITH RECURRENT OR PROGRESSIVE MAPK-ALTERED TUMORS Wright, Karen; Kline, Cassie; Abdelbaki, Mohamed Shebl; Sayour, Elias; Crotty, Erin; Raabe, Eric; Elster, Jennifer; Prados, Michael; Haas-Kogan, Daphne; Mueller, Sabine Share Save
DAMAGE RESPONSE FROM SYSTEMIC RNA VACCINATION RESTORES HUMORAL IMMUNITY IN GLIOBLASTOMA Moor, Rachel; Aghaee, Mahya; Carrera-Justiz, Sheila; Qdaisat, Sadeem; Xie, Chao; Soni, Dhruvkumar; von Roemeling, Christina; Devries, Anna; Wummer, Brandon; Weidert, Frances; Chardon-Robles, Jonathan; Ligon, John; Castillo, Paul; Silver, Natalie; Kline, Cassie; Prados, Michael; Mueller, Sabine; Hwang, Eugene; Rahman, Maryam; Ghiaseddin, Ashley; Mitchell, Duane; Seligson, Nathan; Mendez-Gomez, Hector; Moore, Helen; Sayour, Elias Share Save
EFFECTS OF NEOADJUVANT IMMUNE CHECKPOINT INHIBITION ON PEDIATRIC AND ADULT HIGH-GRADE GLIOMAS Keren-Gill, Hadar; Herrera, Gilbert; Baisiwala, Shivani; Markus, Lauren; Sun, Lu; Everson, Richard; Oren, Michal Yalan; Govender, Dinisha; Margol, Ashley; Chi, Susan; Prados, Michael; Kline, Cassie; Mueller, Sabine; Davidson, Tom Belle; Prins, Robert Share Save
Project HOPE: A spatiotemporal single-cell landscape of high-grade gliomas in children, adolescents and young adults Danielli, Sara G.; Neyazi, Sina; Hack, Olivia A.; Jiang, Li; Lo Cascio, Costanza; Nascimento, Andrezza; Cuong, Nguyen; Rozowsky, Jacob; Liu, Ilon; Hoare, Owen; Shamardani, Karin; E-Koehler, Kennedy Cunli Overline; Gojo, Johannes; Ligon, Keith L.; Baird, Lissa; Alexandrescu, Sanda; Cotter, Jennifer; Prados, Michael; Resnick, Adam; Wang, Lin; Monje, Michelle; Diaz, Aaron; Filbin, Mariella G. Share Save
EARLY INSIGHTS FROM PNOC027: PERSONALIZED TREATMENT APPROACHES BASED ON REAL-TIME DRUG SCREENING AND GENOMIC TESTING IN PEDIATRIC AND ADOLESCENT PATIENTS WITH RECURRENT MEDULLOBLASTOMA Shatara, Margaret; Paul, Megan R.; Long-Boyle, Janel R.; Meyer, Ashley; Raber, Shannon; Yeh-Nayre, Lanipua; Jalkanen, Aimee; Kilburn, Lindsay B.; Packer, Roger J.; Elster, Jennifer D.; Reddy, Alyssa T.; Koschmann, Carl; Kraya, Adam; Resnick, Adam C.; Prados, Michael; Kline, Cassie; Mueller, Sabine; Wechsler-Reya, Robert J.; Rubin, Joshua B. Share Save
PNOC022 REPORT: A COMBINATION THERAPY TRIAL USING AN ADAPTIVE PLATFORM DESIGN FOR PATIENTS WITH DIFFUSE MIDLINE GLIOMA AT INITIAL DIAGNOSIS, POST-RADIATION THERAPY, OR PROGRESSION Kline, Cassie; Franson, Andrea; Banerjee, Anuradha; Reddy, Alyssa T.; Raber, Shannon; Hoffman, Carly; Minturn, Jane; van der Lugt, Jasper; de Vos-Kerkhof, Evelien; van Vuurden, Dannis; Gerber, Nicolas; Stucklin, Ana S. Guerreiro; Kilburn, Lindsay; Elster, Jennifer; Whipple, Nicholas; Cohen, Kenneth; Oren, Michal Yalon; Gardner, Sharon; Cluster, Andrew; Chi, Susan; Landi, Daniel; McCowage, Geoffrey; Vo, Josh; Resnick, Adam; Phillips, Joanna; Bhatia, Aashim; George, Elizabeth; Vossough, Arastoo; Nabavizadeh, Ali; Braunstein, Steve; Gupta, Nalin; Prados, Michael; Waszak, Sebastian; Long-Boyle, Janel; Molinaro, Annette; Dun, Matthew; Koschmann, Carl; Nazarian, Javad; Mueller, Sabine Share Save
PNOC031-INTERNATIONAL TRIAL FOR EMBRYONAL TUMOR WITH MULTILAYERED ROSETTES Hanson, Derek; Chi, Susan; Braunstein, Steve; Elhalawani, Hesham; Kool, Marcel; Filbin, Mariella; Gojo, Johannes; Plasschaert, Sabine; Von Hoff, Katja; Margol, Ashley; Kline, Cassie; Molinaro, Annette; Prados, Michael; Mueller, Sabine Share Save
PNOC005: ONCOLYTIC MEASLES VIRUS FOR THE TREATMENT OF CHILDREN AND YOUNG ADULTS WITH RECURRENT MEDULLOBLASTOMA OR ATYPICAL TERATOID RHABDOID TUMOR Kline, Cassie; Yu, Bohyeon; Knowles, Truman; Ranavaya, Aeesha; Minturn, Jane; Banerjee, Anuradha; Leary, Sarah; Abdelbaki, Mohamed; Whipple, Nicholas; Goldman, Stewart; Margol, Ashley; Dabobo, Nour; Rauschecker, Andreas; George, Elizabeth; Nabavizadeh, Ali; Hoare, Owen; Jung, Jangham; Phillips, Joanna; Prados, Michael; Molinaro, Annette; Gupta, Nalin; Raffel, Corey; Cole, Kristina; Diaz, Aaron; Mueller, Sabine Share Save
Towards consistency in pediatric brain tumor measurements: Challenges, solutions, and the role of artificial intelligence-based segmentation Familiar, Ariana M.; Kazerooni, Anahita Fathi; Vossough, Arastoo; Ware, Jeffrey B.; Bagheri, Sina; Khalili, Nastaran; Anderson, Hannah; Haldar, Debanjan; Storm, Phillip B.; Resnick, Adam C.; Kann, Benjamin H.; Aboian, Mariam; Kline, Cassie; Weller, Michael; Huang, Raymond Y.; Chang, Susan M.; Fangusaro, Jason R.; Hoffman, Lindsey M.; Mueller, Sabine; Prados, Michael; Nabavizadeh, Ali Share Save
Comparison of Volumetric and 2D Measurements and Longitudinal Trajectories in the Response Assessment of BRAF V600E-Mutant Pediatric Gliomas in the Pacific Pediatric Neuro-Oncology Consortium Clinical Trial Ramakrishnan, Divya; Bruningk, Sarah C.; von Reppert, Marc; Memon, Fatima; Maleki, Nazanin; Aneja, Sanjay; Kazerooni, Anahita Fathi; Nabavizadeh, Ali; Lin, MingDe; Bousabarah, Khaled; Molinaro, Annette; Nicolaides, Theodore; Prados, Michael; Mueller, Sabine; Aboian, Mariam S. Share Save
Rational combination platform trial design for children and young adults with diffuse midline glioma: A report from PNOC Mueller, Sabine; Kline, Cassie; Franson, Andrea; van der Lugt, Jasper; Prados, Michael; Waszak, Sebastian M.; Plasschaert, Sabine L. A.; Molinaro, Annette M.; Koschmann, Carl; Nazarian, Javad Share Save
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OpenPBTA: The Open Pediatric Brain Tumor Atlas Shapiro, Joshua A.; Gaonkar, Krutika S.; Spielman, Stephanie J.; Savonen, Candace L.; Bethell, Chante J.; Jin, Run; Rathi, Komal S.; Zhu, Yuankun; Egolf, Laura E.; Farrow, Bailey K.; Miller, Daniel P.; Yang, Yang; Koganti, Tejaswi; Noureen, Nighat; Koptyra, Mateusz P.; Duong, Nhat; Santi, Mariarita; Kim, Jung; Robins, Shannon; Storm, Phillip B.; Mack, Stephen C.; Lilly, Jena, V; Xie, Hongbo M.; Jain, Payal; Raman, Pichai; Rood, Brian R.; Lulla, Rishi R.; Nazarian, Javad; Kraya, Adam A.; Vaksman, Zalman; Heath, Allison P.; Kline, Cassie; Scolaro, Laura; Viaene, Angela N.; Huang, Xiaoyan; Way, Gregory P.; Foltz, Steven M.; Zhang, Bo; Poetsch, Anna R.; Mueller, Sabine; Ennis, Brian M.; Prados, Michael; Diskin, Sharon J.; Zheng, Siyuan; Guo, Yiran; Kannan, Shrivats; Waanders, Angela J.; Margol, Ashley S.; Kim, Meen Chul; Hanson, Derek; Van Kuren, Nicholas; Wong, Jessica; Kaufman, Rebecca S.; Coleman, Noel; Blackden, Christopher; Cole, Kristina A.; Mason, Jennifer L.; Madsen, Peter J.; Koschmann, Carl J.; Stewart, Douglas R.; Wafula, Eric; Brown, Miguel A.; Resnick, Adam C.; Greene, Casey S.; Rokita, Jo Lynne; Taroni, Jaclyn N. Share Save
PNOC015: Repeated convection-enhanced delivery of MTX110 (aqueous panobinostat) in children with newly diagnosed diffuse intrinsic pontine glioma Mueller, Sabine; Kline, Cassie; Stoller, Schuyler; Lundy, Shannon; Christopher, Lauren; Reddy, Alyssa T.; Banerjee, Anu; Cooney, Tabitha M.; Raber, Shannon; Hoffman, Carly; Luks, Tracy; Wembacher-Schroeder, Eva; Lummel, Nina; Zhang, Yalan; Bonner, Erin R.; Nazarian, Javad; Molinaro, Annette M.; Prados, Michael; Villanueva-Meyer, Javier E.; Gupta, Nalin Share Save
Evaluating preclinical evidence for clinical translation in childhood brain tumours: Guidelines from the CONNECT, PNOC, and ITCC brain networks Jones, Chris; Straathof, Karin; Fouladi, Maryam; Hargrave, Darren; Prados, Michael; Resnick, Adam; Doz, Francois; Jones, David T. W.; Mueller, Sabine Share Save
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