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Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity Bennett, Craig L.; Dastidar, Somasish; Arnold, Frederick J.; McKinstry, Spencer U.; Stockford, Cameron; Freibaum, Brian D.; Sopher, Bryce L.; Wu, Meilin; Seidner, Glen; Joiner, William; Taylor, J. Paul; West, Ryan J. H.; La Spada, Albert R. Share Save
Differential effects of various genetic mouse models of the mechanistic target of rapamycin complex I inhibition on heart failure Dai, Dao-Fu; Liu, Yonggang; Basisty, Nathan; Karunadharma, Pabalu; Dastidar, Somasish G.; Chiao, Ying Ann; Chen, Tony; Beyer, Richard P.; Chin, Michael T.; Maccoss, Michael; La Spada, Albert R.; Rabinovitch, Peter S. Share Save
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis Ling, Shuo-Chien; Dastidar, Somasish Ghosh; Tokunaga, Seiya; Ho, Wan Yun; Lim, Kenneth; Ilieva, Hristelina; Parone, Philippe A.; Tyan, Sheue-Houy; Tse, Tsemay M.; Chang, Jer-Cherng; Platoshyn, Oleksandr; Bui, Ngoc B.; Anh Bui; Vetto, Anne; Sun, Shuying; McAlonis-Downes, Melissa; Han, Joo Seok; Swing, Debbie; Kapeli, Katannya; Yeo, Gene W.; Tessarollo, Lino; Marsala, Martin; Shaw, Christopher E.; Tucker-Kellogg, Greg; La Spada, Albert R.; lagier-Tourenne, Clotilde; Da Cruz, Sandrine; Cleveland, Don W. Share Save
Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients Bennett, Craig L.; Dastidar, Somasish G.; Ling, Shuo-Chien; Malik, Bilal; Ashe, Travis; Wadhwa, Mandheer; Miller, Derek B.; Lee, Changwoo; Mitchell, Matthew B.; van Es, Michael A.; Grunseich, Christopher; Chen, Yingzhang; Sopher, Bryce L.; Greensmith, Linda; Cleveland, Don W.; La Spada, Albert R. Share Save
Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice Tsai, Shih-Yin; Rodriguez, Ariana A.; Dastidar, Somasish G.; Del Greco, Elizabeth; Carr, Kaili Lia; Sitzmann, Joanna M.; Academia, Emmeline C.; Viray, Christian Michael; Martinez, Lizbeth Leon; Kaplowitz, Brian Stephen; Ashe, Travis D.; La Spada, Albert R.; Kennedy, Brian K. Share Save
Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity Tsai, Shihyin; Sitzmann, Joanna M.; Dastidar, Somasish G.; Rodriguez, Ariana A.; Vu, Stephanie L.; McDonald, Circe E.; Academia, Emmeline C.; O'Leary, Monique N.; Ashe, Travis D.; La Spada, Albert R.; Kennedy, Brian K. Share Save
Let-7 Coordinately Suppresses Components of the Amino Acid Sensing Pathway to Repress mTORC1 and Induce Autophagy Dubinsky, Amy N.; Dastidar, Somasish Ghosh; Hsu, Cynthia L.; Zahra, Rabaab; Djakovic, Stevan N.; Duarte, Sonia; Esau, Christine C.; Spencer, Brian; Ashe, Travis D.; Fischer, Kimberlee M.; MacKenna, Deidre A.; Sopher, Bryce L.; Masliah, Eliezer; Gaasterland, Terry; Chau, B. Nelson; de Almeida, Luis Pereira; Morrison, Bradley E.; La Spada, Albert R. Share Save
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