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FBXO22 deficiency defines a pleiotropic syndrome of growth restriction and multi-system anomalies associated with a unique epigenetic signature Ramakrishna, NB; Sahari, UB; Johmura, Y; Ali, NA; Alghamdi, M; Bauer, P; Khan, S; Ordoñez, N; Ferreira, M; Basto, JP; Alkuraya, FS; Faqeih, EA; Mori, M; Almontashiri, NAM; Al Shamsi, A; Elghazali, G; Abu Subieh, H; Al Ojaimi, M; El-Hattab, AW; Al-Kindi, SAS; Alhashmi, N; Alhabshan, F; Al Saman, A; Tfayli, H; Arabi, M; Khalifeh, S; Taylor, A; Alfadhel, M; Jain, R; Sinha, S; Shenbagam, S; Ramachandran, R; Altunoglu, U; Jacob, A; Thalange, N; El Bejjani, M; Perrin, A; Shin, JW; Al-Maawali, A; Al-Shidhani, A; Al-Futaisi, A; Rabea, F; Chekroun, I; Almarri, MA; Ohta, T; Nakanishi, M; Alsheikh-Ali, A; Ali, FR; Bertoli-Avella, AM; Reversade, B; Abou Tayoun, A Share Save
Signaling networks in cancer stromal senescent cells establish malignant microenvironment Zhang, Yue; Wang, Teh-Wei; Tamatani, Maho; Zeng, Xinyi; Nakamura, Lindo; Omori, Satotaka; Yamaguchi, Kiyoshi; Hatakeyama, Seira; Shimizu, Eigo; Yamazaki, Satoshi; Furukawa, Yoichi; Imoto, Seiya; Johmura, Yoshikazu; Nakanishi, Makoto Share Save
Ribosomal S6 kinase (RSK) plays a critical role in DNA damage response via the phosphorylation of histone lysine demethylase KDM4B Wu, Wenwen; Zhu, Jing; Nihira, Naoe Taira; Togashi, Yukiko; Goda, Atsushi; Koike, Junki; Yamaguchi, Kiyoshi; Furukawa, Yoichi; Tomita, Takuya; Saeki, Yasushi; Johmura, Yoshikazu; Nakanishi, Makoto; Miyoshi, Yasuo; Ohta, Tomohiko Share Save
Preexisting senescent fibroblasts in the aged bladder create a tumor-permissive niche through CXCL12 secretion Meguro, Satoru; Johmura, Yoshikazu; Wang, Teh-Wei; Kawakami, Satoshi; Tanimoto, Shota; Omori, Satotaka; Okamura, Yuki T.; Hoshi, Seiji; Kayama, Emina; Yamaguchi, Kiyoshi; Hatakeyama, Seira; Yamazaki, Satoshi; Shimizu, Eigo; Imoto, Seiya; Furukawa, Yoichi; Kojima, Yoshiyuki; Nakanishi, Makoto Share Save
M2 macrophage-derived TGF-β induces age-associated loss of adipogenesis through progenitor cell senescence Zeng, Xinyi; Wang, Teh-Wei; Yamaguchi, Kiyoshi; Hatakeyama, Seira; Yamazaki, Satoshi; Shimizu, Eigo; Imoto, Seiya; Furukawa, Yoichi; Johmura, Yoshikazu; Nakanishi, Makoto Share Save
Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts Suda, Kojiro; Moriyama, Yohsuke; Razali, Nurhanani; Chiu, Yatzu; Masukagami, Yumiko; Nishimura, Koutarou; Barbee, Hunter; Takase, Hiroshi; Sugiyama, Shinju; Yamazaki, Yuta; Sato, Yoshikatsu; Higashiyama, Tetsuya; Johmura, Yoshikazu; Nakanishi, Makoto; Kono, Keiko Share Save
LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits Li, Dan; Johmura, Yoshikazu; Morimoto, Satoru; Doi, Miyuki; Nakanishi, Keiko; Ozawa, Manabu; Tsunekawa, Yuji; Inoue-Yamauchi, Akane; Naruse, Hiroya; Matsukawa, Takashi; Takeshita, Yukio; Suzuki, Naoki; Aoki, Masashi; Nishiyama, Ayumi; Zeng, Xin; Konishi, Chieko; Suzuki, Narumi; Nishiyama, Atsuya; Harris, Alexander Stephen; Morita, Mariko; Yamaguchi, Kiyoshi; Furukawa, Yoichi; Nakai, Kenta; Tsuji, Shoji; Yamazaki, Satoshi; Yamanashi, Yuji; Shimada, Shoichi; Okada, Takashi; Okano, Hideyuki; Toda, Tatsushi; Nakanishi, Makoto Share Save
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Fbxo22 regulates estrogen signaling and suppresses tamoxifen-induced endometrial cancer Goda, Atsushi; Meguro, Satoru; Johmura, Yoshikazu; Wu, Wenwen; Maeda, Ichiro; Sugishita, Yodo; Suzuki, Nao; Miyoshi, Yasuo; Koike, Junki; Nakanishi, Makoto; Ohta, Tomohiko Share Save
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TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis Suzuki, Narumi; Johmura, Yoshikazu; Wang, Teh-Wei; Migita, Toshiro; Wu, Wenwen; Noguchi, Rei; Yamaguchi, Kiyoshi; Furukawa, Yoichi; Nakamura, Shuhei; Miyoshi, Ichiro; Yoshimori, Tamotsu; Ohta, Tomohiko; Nakanishi, Makoto Share Save
A 3D tissue model-on-a-chip for studying the effects of human senescent fibroblasts on blood vessels Pauty, Joris; Nakano, Shizuka; Usuba, Ryo; Nakajima, Tadaaki; Johmura, Yoshikazu; Omori, Satotaka; Sakamoto, Naoya; Kikuchi, Akihiko; Nakanishi, Makoto; Matsunaga, Yukiko T. Share Save
Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo Omori, Satotaka; Wang, Teh-Wei; Johmura, Yoshikazu; Kanai, Tomomi; Nakano, Yasuhiro; Kido, Taketomo; Susaki, Etsuo A.; Nakajima, Takuya; Shichino, Shigeyuki; Ueha, Satoshi; Ozawa, Manabu; Yokote, Kisho; Kumamoto, Soichiro; Nishiyama, Atsuya; Sakamoto, Takeharu; Yamaguchi, Kiyoshi; Hatakeyama, Seira; Shimizu, Eigo; Katayama, Kotoe; Yamada, Yasuhiro; Yamazaki, Satoshi; Iwasaki, Kanako; Miyoshi, Chika; Funato, Hiromasa; Yanagisawa, Masashi; Ueno, Hiroo; Imoto, Seiya; Furukawa, Yoichi; Yoshida, Nobuaki; Matsushima, Kouji; Ueda, Hiroki R.; Miyajima, Atsushi; Nakanishi, Makoto Share Save
Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase Nishimura, Koutarou; Johmura, Yoshikazu; Deguchi, Katashi; Jiang, Zixian; Uchida, Kazuhiko S. K.; Suzuki, Narumi; Shimada, Midori; Chiba, Yoshie; Hirota, Toru; Yoshimura, Shige H.; Kono, Keiko; Nakanishi, Makoto Share Save
Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer Johmura, Yoshikazu; Maeda, Ichiro; Suzuki, Narumi; Wu, Wenwen; Goda, Atsushi; Morita, Mariko; Yamaguchi, Kiyoshi; Yamamoto, Mizuki; Nagasawa, Satoi; Kojima, Yasuyuki; Tsugawa, Koichiro; Inoue, Natsuko; Miyoshi, Yasuo; Osako, Tomo; Akiyama, Futoshi; Maruyama, Reo; Inoue, Jun-ichiro; Furukawa, Yoichi; Ohta, Tomohiko; Nakanishi, Makoto Share Save
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