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H

Hideyuki Okano

keio university

145H-index
1.8KPaper Count
8.6WCitation Count
Published Papers 599
Publication Date
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An iPSC-derived neural progenitor cell therapy for subacute spinal cord injury: a phase 1 trial with long-term follow-up
errNature Medicine
IF50
err2026-07-21
err0
errOAAI
errKeiko Sugai; Osahiko Tsuji; Kanehiro Fujiyoshi; Masahiro Ozaki; Takayuki Abe; Tsuneo Kohzuki; Hiroki Okawara; Tomonori Sawada; Miho Sumida; Ema Yoshioka; Tomoko Shofuda; Shioko Kawashima; Ryo Yamaguchi; Munehisa Shinozaki; Naoko Takasu; Narihito Nagoshi; Toshiki Okubo; Jun Kohyama; Takeshi Maeda; Yoshiyuki Yato; Yonehiro Kanemura; Shinya Yamanaka; Masaya Nakamura; Hideyuki Okano
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Therapeutic frontiers in ALS: iPSC-based drug discovery, cell therapy, and gene therapy—Advances through 2026
errRegenerative Therapy
IF3.5
err2026-06-15
err0
errOAAI
errSatoru Morimoto; Chris Kato; Shinichi Takahashi; Hideyuki Okano
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Year in review 2025–2026: A year of progress and purpose
errStem Cell Reports
IF5.1
err2026-06-09
err0
errOAAI
errHideyuki Okano
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errSave
Antibacterial silver ion-coated dental implants suppress peri-implantitis in a murine model
errScientific Reports
IF3.9
err2026-05-14
err0
errOAAI
errMana Nasu; Tomoya Soma; Hidetaka Miyashita; Takehito Ouchi; Yoshitaka Kase; Takazumi Yasui; Fuka Homma; Kitaru Suzuki; Takeshi Miyamoto; Hideyuki Okano; Masaya Nakamura; Taneaki Nakagawa; Mamoru Aizawa; Satoru Morikawa
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Diagnostic potential of cryptic exon-derived peptides in serum extracellular vesicles for sporadic amyotrophic lateral sclerosis
errInflammation and Regeneration
IF6.6
err2026-01-29
err0
errOAAI
errKoki Takahashi; Chris Kato; Koji Ueda; Shiho Nakamura; Fumiko Ozawa; Nobuko Moritoki; Shinsuke Shibata; Shinichi Takahashi; Satoru Morimoto; Hideyuki Okano
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errSave
Human induced pluripotent stem cell-derived neural stem/progenitor cell therapy for spinal cord injury: preclinical advances and translational perspectives
errStem Cells Translational Medicine
IF4.9
err2026-01-01
err0
PREAI
errOgaki, Ryo; Nagoshi, Narihito; Okano, Hideyuki; Nakamura, Masaya
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errSave
An acyclic nucleic acid-modified siRNA targeting CAG expansions for polyglutamine disease treatment
errMolecular Therapy Nucleic Acids
IF6.1
err2025-12-11
err0
errOAAI
errKentaro Maeda; Tomoki Hirunagi; Kentaro Sahashi; Yukiko Kamiya; Madoka Iida; Kenji Sakakibara; Kazunari Onodera; Manabu Ohyama; Yohei Okada; Hideyuki Okano; Hiroyuki Asanuma; Masahisa Katsuno
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errSave
A genome-wide association study identifies the GPM6A locus associated with age at onset in ALS
errCommunications Biology
IF5.1
err2025-12-05
err0
errOAAI
errRyoichi Nakamura; Genki Tohnai; Naoki Atsuta; Yumi Matsuda; Satoru Morimoto; Daisuke Ito; Masahisa Katsuno; Yuishin Izumi; Mitsuya Morita; Ikuko Iwata; Ichiro Yabe; Tomoko Nakazato; Nobutaka Hattori; Takehisa Hirayama; Osamu Kano; Asako Tamura; Naoki Suzuki; Masashi Aoki; Kazumoto Shibuya; Satoshi Kuwabara; Masaya Oda; Rina Hashimoto; Ikuko Aiba; Tomohiko Ishihara; Osamu Onodera; Toru Yamashita; Hiroyuki Ishiura; Kota Bokuda; Toshio Shimizu; Yoshio Ikeda; Kazuko Hasegawa; Fumiaki Tanaka; Takanori Yokota; Kazuaki Kanai; Yu-ichi Noto; Ryuji Kaji; Hirohisa Watanabe; Tomoko Konishi; Mikiko Hasegawa; Hozuki Fukaya; Jun-ichi Niwa; Manabu Doyu; Yohei Okada; Shiho Nakamura; Fumiko Ozawa; Hideyuki Okano; Masahiro Nakatochi; Gen Sobue
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errSave
Generation of Human Melanocytes from Induced Pluripotent Stem Cells (vol 6, e16182, 2011)
errPLOS ONE
IF2.6
err2025-11-24
err0
errOAAI
errOhta, Shigeki; Imaizumi, Yoichi; Okada, Yohei; Akamatsu, Wado; Kuwahara, Reiko; Ohyama, Manabu; Amagai, Masayuki; Matsuzaki, Yumi; Yamanaka, Shinya; Okano, Hideyuki; Kawakami, Yutaka
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errSave
Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils
errAlzheimer's Research & Therapy
IF7.6
err2025-11-21
err0
errOAAI
errHayato Etani; Sho Takatori; Wenbo Wang; Jumpei Omi; Yusuke Amiya; Aika Akahori; Hirotaka Watanabe; Iki Sonn; Hideyuki Okano; Norikazu Hara; Mai Hasegawa; Akinori Miyashita; Masataka Kikuchi; Takeshi Ikeuchi; Maho Morishima; Yuko Saito; Shigeo Murayama; Takashi Saito; Takaomi C. Saido; Toshiyuki Takai; Tomohiko Ohwada; Junken Aoki; Taisuke Tomita
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Visualization and quantification of facial muscles with 9.4T MRI-DTI in common marmosets (Callithrix jacchus)
errROYAL SOCIETY OPEN SCIENCE
IF2.9
err2025-11-12
err0
PREAI
errMuta, Kanako; Correia-Caeiro, Catia; Hata, Junichi; Miyabe-Nishiwaki, Takako; Kurihara, Sho; Takae, Yuri; Okano, Hirotaka James; Okano, Hideyuki; Burrows, Anne
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errSave
Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome
errNature Communications
IF15.7
err2025-10-28
err0
errOAAI
errAkisa Nemoto; Kent Imaizumi; Fuyuki Miya; Yuka Hiroi; Mamiko Yamada; Hirosato Ideno; Shinji Saitoh; Kenjiro Kosaki; Hironobu Okuno; Hideyuki Okano
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errSave
Cerebrospinal fluid extracellular vesicle-derived miR-9-3p in spinal cord injury with neuroprotective implications and biomarker development
errCommunications Biology
IF5.1
err2025-10-27
err0
errOAAI
errTomoharu Tanaka; Satoru Morimoto; Keitaro Ito; Kaori Yasutake; Chris Kato; Munehisa Shinozaki; Kota Suda; Takeshi Maeda; Yoshiyuki Yato; Masaya Nakamura; Hideyuki Okano; Narihito Nagoshi
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errSave
Modeling Mitochondrial Disease Using Brain Organoids: A Focus on Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes
errJOVE-JOURNAL OF VISUALIZED EXPERIMENTS
IF1
err2025-10-01
err0
PREAI
errKawano, Shihori; Saegusa, Chika; Masano, Yusuke; Becker, Franziska; Nakamura, Mari; Shiozawa, Seiji; Fujikura, Junji; Toyohara, Takafumi; Abe, Takaaki; Okano, Hideyuki; Fujioka, Masato
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errSave
Generation of a human iPSC line with EGFP knock-in at the ATRX locus for visualization of chromatin remodeler dynamics and nuclear condensate formation
errSTEM CELL RESEARCH
IF0.7
err2025-10-01
err0
errOAAI
errTomooka, Ryo; Okano, Hideyuki; Kohyama, Jun
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Corrigendum to “Retinoic-acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells” [Develop. Biol. 275 (2004) 124-42]
errDevelopmental Biology
IF2.1
err2025-08-22
err0
PREAI
errYohei Okada; Takuya Shimazaki; Gen Sobue; Hideyuki Okano
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Investigation of early axonal phenotypes in an iPSC-derived ALS cellular model using a microfluidic device
errFrontiers in Cellular Neuroscience
IF4
err2025-08-21
err0
errOAAI
errAsako Otomo; Keiko Nishijima; Yuta Murakami; Mitsuru Ishikawa; Haruka Yudahira; Kento Shimakura; Hideyuki Okano; Masashi Aoki; Hiroshi Kimura; Shinji Hadano
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errSave
Ropinirole Functions Through a Dopamine Receptor D2-Independent Mechanism to Ameliorate Amyotrophic Lateral Sclerosis Phenotypes in TARDBP-Mutant iPSC-Derived Motor Neurons
errJournal of Neurochemistry
IF4
err2025-08-18
err0
errOAAI
errHirotsugu Asano; Tetsuya Kawaguchi; Chris Kato; Satoru Morimoto; Masato Yano; Maki Minaguchi; Daisuke Yasuda; Komei Fukushima; Hideyuki Okano
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errSave
Time series analysis of ex-vivo ischemia-reperfused heart using Q-space imaging
errScientific Reports
IF3.9
err2025-08-10
err0
errOAAI
errGenki Ichihara; Junichi Hata; Daisuke Nakashima; Kyohei Daigo; Kazuhisa Sugai; Yuji Iwasawa; Motoaki Sano; Masaya Nakamura; Hideyuki Okano; Kazuki Sato; Yoshinori Katsumata
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errSave
Phase separated condensates of ATRX regulate neural progenitor identity
errNature Communications
IF15.7
err2025-07-14
err0
errOAAI
errRyo Tomooka; Tsukasa Sanosaka; Tamami Miyagi; Tomoko Andoh-Noda; Satoe Banno; Noriko Mizota; Kohsuke Kanekura; Hideyuki Okano; Jun Kohyama
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
T
Terrence J. Sejnowski
H-index: 153 · Papers: 993
N
Noboru Mizushima
H-index: 141 · Papers: 423
T
Toshio Suda
H-index: 139 · Papers: 1.1K
J
Jean‐Pierre J. Issa
H-index: 130 · Papers: 984
D
David C. Van Essen
H-index: 127 · Papers: 348
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