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C

Christine F. Brainson

University of Kentucky

14H-index
134Paper Count
929Citation Count
Published Papers 30
Publication Date
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A Cyclometalated Gold(III) Complex Targets Mitochondrial VDAC1 to Drive Immunometabolic Reprogramming in Cancer
errJournal of the American Chemical Society
IF15.6
err2026-06-11
err0
PREAI
errSean T. Gilpatrick; Jong Hyun Kim; Sarayu Bhogoju; Neeraj Kapur; Udara Munugoda; Jovita Daraezinwa; Sean Parkin; Terrence A. Barrett; Christine F. Brainson; Daniel R. Plaugher; Samuel G. Awuah
errShare
errSave
An Agrin-YAP/TAZ Rigidity Sensing Module Drives EGFR-Addicted Lung Tumorigenesis
errADVANCED SCIENCE
IF14.1
err2025-03-31
err0
errOAAI
errMokhtari, RB; Sampath, D; Eversole, P; Lin, MOY; Bosykh, DA; Boopathy, GTK; Sivakumar, A; Wang, CC; Kumar, R; Sheng, JYP; Karasik, E; Foster, BA; Yu, H; Ling, X; Wu, WJ; Li, FZ; Ohler, ZW; Brainson, CF; Goodrich, DW; Hong, WJ; Chakraborty, S
errShare
errSave
Examining Geographic Disparity: Variation in Cancer Outcomes Within Appalachia
errJOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
IF3.4
err2025-02-06
err0
PREAI
errBurus, Todd; Hull, Pamela C.; Kuhs, Krystle A. Lang; Gao, Tianyan; Brainson, Christine F.; Evers, B. Mark
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errSave
S6K1 is a Targetable Vulnerability in Tumors Exhibiting Plasticity and Therapy Resistance
errINTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
IF10
err2025-01-01
err0
PREAI
errGanguly, Saptadwipa; Burikhanov, Ravshan; Sviripa, Vitaliy M.; Ellingson, Sally; Jiang, Jieyun; Gosser, Christian M.; Orren, David; Goellner, Eva M.; Shenoy, Gautham G.; Rao, Mahadev; D'Orazio, John; Brainson, Christine F.; Zhan, Chang-Guo; Spielmann, Peter H.; Watt, David S.; Rangnekar, Vivek M.
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errSave
L858R/L718Q and L858R/L792H Mutations of EGFR Inducing Resistance Against Osimertinib by Forming Additional Hydrogen Bonds
errPROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
IF2.8
err2024-11-04
err0
PREAI
errImam, Ibrahim A.; Al Adawi, Shatha; Liu, Xiaoqi; Ellingson, Sally; Brainson, Christine F.; Moseley, Hunter N. B.; Zinner, Ralph; Zhang, Shulin; Shao, Qing
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errSave
Therapeutic potential of tumor-infiltrating lymphocytes in non-small cell lung cancer
errCANCER LETTERS
IF10.1
err2024-11-01
err0
PREAI
errPlaugher, Daniel R.; Childress, Avery R.; Gosser, Christian M.; Esoe, Dave-Preston; Naughton, Kassandra J.; Hao, Zhonglin; Brainson, Christine F.
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errSave
Metabolic reprogramming driven by EZH2 inhibition depends on cell-matrix interactions
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-01-01
err0
errOAAI
errFan, Teresa W. -M; Islam, Jahid M. M.; Higashi, Richard M.; Lin, Penghui; Brainson, Christine F.; Lane, Andrew N.
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errSave
Using Artificial Intelligence to Identify Tumor Microenvironment Heterogeneity in Non-Small Cell Lung Cancers
errLABORATORY INVESTIGATION
IF4.2
err2023-08-01
err6
PREAI
errDuCote, Tanner J.; Naughton, Kassandra J.; Skaggs, Erika M.; Bocklage, Therese J.; Allison, Derek B.; Brainson, Christine F.
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errSave
Phosphorylation of AHR by PLK1 promotes metastasis of LUAD via upregulation of DIO2
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errLi, Chaohao; He, Daheng; Mao, Fengyi; Wang, Xinyi; Hao, Yanning; Kong, Yifan; Brainson, Christine F.; Liu, Jinghui; Zhang, Yanquan; Wang, Ruixin; Zhang, Qiongsi; Li, Zhiguo; Rao, Xiongjian; Wu, Sai; Wang, Chi; Wei, Qiou; Wang, Jianlin; Liu, Xiaoqi
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errSave
Polycomb deficiency drives a FOXP2-high aggressive state targetable by epigenetic inhibitors
errNATURE COMMUNICATIONS
IF15.7
err2023-01-20
err3
errOAAI
errChen, Fan; Byrd, Aria L. L.; Liu, Jinpeng; Flight, Robert M. M.; DuCote, Tanner J. J.; Naughton, Kassandra J. J.; Song, Xiulong; Edgin, Abigail R. R.; Lukyanchuk, Alexsandr; Dixon, Danielle T. T.; Gosser, Christian M. M.; Esoe, Dave-Preston; Jayswal, Rani D. D.; Orkin, Stuart H. H.; Moseley, Hunter N. B.; Wang, Chi; Brainson, Christine Fillmore
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errSave
Dysregulated Polycomb Repressive Complex 2 contributes to chronic obstructive pulmonary disease by rewiring stem cell fate
errSTEM CELL REPORTS
IF5.1
err2023-01-01
err2
errOAAI
errByrd, Aria L.; Qu, Xufeng; Lukyanchuk, Alexsandr; Liu, Jinpeng; Chen, Fan; Naughton, Kassandra J.; DuCote, Tanner J.; Song, Xiulong; Bowman, Hannah C.; Zhao, Yanming; Edgin, Abigail R.; Wang, Chi; Liu, Jinze; Brainson, Christine Fillmore
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errSave
The kinase PLK1 promotes the development of Kras/Tp53-mutant lung adenocarcinoma through transcriptional activation of the receptor RET
errSCIENCE SIGNALING
IF6.6
err2022-10-04
err8
errOAAI
errKong, Yifan; Allison, Derek B.; Zhang, Qiongsi; He, Daheng; Li, Yuntong; Mao, Fengyi; Li, Chaohao; Li, Zhiguo; Zhang, Yanquan; Wang, Jianlin; Wang, Chi; Brainson, Christine F.; Liu, Xiaoqi
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errSave
Aberrant glycogen accumulation alters gene expression and promotes lung tumor progression in vivo
errFASEB JOURNAL
IF4.2
err2022-05-13
err0
PREAI
errLamb, Jessica F.; Conroy, Lindsey R.; James, Alexis N.; Buoncristiani, Michael D.; Relich, Eric R.; Brainson, Christine F.; Sun, Ramon C.
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errSave
EZH2 inhibition confers PIK3CA-driven lung tumors enhanced sensitivity to PI3K inhibition
errCANCER LETTERS
IF10.1
err2022-01-01
err19
errOAAI
errChen, Fan; Liu, Jinpeng; Song, Xiulong; DuCote, Tanner J.; Byrd, Aria L.; Wang, Chi; Brainson, Christine F.
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errSave
Description of a Lung Cancer Hotspot: Disparities in Lung Cancer Histology, Incidence, and Survival in Kentucky and Appalachian Kentucky
errCLINICAL LUNG CANCER
IF3.3
err2021-11-01
err5
errOAAI
errBrainson, Christine F.; Huang, Bin; Chen, Quan; McLouth, Laurie E.; He, Chunyan; Hao, Zhonglin; Arnold, Susanne M.; Zinner, Ralph G.; Mullett, Timothy W.; Bocklage, Therese J.; Orren, David K.; Villano, John L.; Durbin, Eric B.
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errSave
Cellular Origins of EGFR-Driven Lung Cancer Cells Determine Sensitivity to Therapy
errADVANCED SCIENCE
IF14.1
err2021-10-07
err15
errOAAI
errChen, Fan; Liu, Jinpeng; Flight, Robert M.; Naughton, Kassandra J.; Lukyanchuk, Alexsandr; Edgin, Abigail R.; Song, Xiulong; Zhang, Haikuo; Wong, Kwok-Kin; Moseley, Hunter N. B.; Wang, Chi; Brainson, Christine F.
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errSave
Brain glycogen serves as a critical glucosamine cache required for protein glycosylation
errCELL METABOLISM
IF30.9
err2021-07-01
err49
errOAAI
errSun, Ramon C.; Young, Lyndsay E. A.; Bruntz, Ronald C.; Markussen, Kia H.; Zhou, Zhengqiu; Conroy, Lindsey R.; Hawkinson, Tara R.; Clarke, Harrison A.; Stanback, Alexandra E.; Macedo, Jessica K. A.; Emanuelle, Shane; Brewer, M. Kathryn; Rondon, Alberto L.; Mestas, Annette; Sanders, William C.; Mahalingan, Krishna K.; Tang, Buyun; Chikwana, Vimbai M.; Segvich, Dyann M.; Contreras, Christopher J.; Allenger, Elizabeth J.; Brainson, Christine F.; Johnson, Lance A.; Taylor, Richard E.; Armstrong, Dustin D.; Shaffer, Robert; Waechter, Charles J.; Vander Kooi, Craig W.; DePaoli-Roach, Anna A.; Roach, Peter J.; Hurley, Thomas D.; Drake, Richard R.; Gentry, Matthew S.
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errSave
BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency
errCANCER RESEARCH
IF16.6
err2020-09-15
err38
errOAAI
errGupta, Manav; Concepcion, Carla P.; Fahey, Caroline G.; Keshishian, Hasmik; Bhutkar, Arjun; Brainson, Christine F.; Sanchez-Rivera, Francisco J.; Pessina, Patrizia; Kim, Jonathan Y.; Simoneau, Antoine; Paschini, Margherita; Beytagh, Mary C.; Stanclift, Caroline R.; Schenone, Monica; Mani, D. R.; Li, Chendi; Oh, Audris; Li, Fei; Hu, Hai; Karatza, Angeliki; Bronson, Roderick T.; Shaw, Alice T.; Hata, Aaron N.; Wong, Kwok-Kin; Zou, Lee; Carr, Steven A.; Jacks, Tyler; Kim, Carla F.
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errSave
Nuclear Glycogenolysis Modulates Histone Acetylation in Human Non-Small Cell Lung Cancers
errCELL METABOLISM
IF30.9
err2019-11-01
err82
errOAAI
errSun, Ramon C.; Dukhande, Vikas V.; Zhou, Zhengqiu; Young, Lyndsay E. A.; Emanuelle, Shane; Brainson, Christine Fillmore; Gentry, Matthew S.
errShare
errSave
Activity of polycomb repressive complex 2 determines sensitivity to epigenetic therapy
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errChen, Fan; Brainson, Christine F.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Michael A. Matthay
H-index: 169 · Papers: 1.3K
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Roderick T. Bronson
H-index: 164 · Papers: 1.1K
T
Tyler Jacks
H-index: 158 · Papers: 817
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