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E

Elsa N. Bou Ghanem

university at buffalo

20H-index
66Paper Count
1.1KCitation Count
Published Papers 23
Publication Date
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Host Aging Induces a Senescent-Like Phenotype in Neutrophils and Altered Transcriptional Responses to Streptococcus pneumoniae
errAging Cell
IF7.1
err2026-03-02
err0
errOAAI
errMichael C. Battaglia; Manmeet Bhalla; Brandon Marzullo; Anagha Betadpur; Alexsandra P. Lenhard; Rania Hassan Mohamed; Murat C. Kalem; Lauren R. Heinzinger; Pathricia A. Leus; Samuel Labarron; Lee Ann Garrett-Sinha; Joan Mecsas; Anna Blumental-Perry; Elsa N. Bou Ghanem
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errSave
Basal activation of ERK1/2 blunts the antimicrobial activity of neutrophils from old hosts against antibody-opsonized Streptococcus pneumoniae
errJournal of Leukocyte Biology
IF3.1
err2026-01-19
err0
PREAI
errShaunna R Simmons; Annabel Rivera; Elsa N Bou Ghanem
errShare
errSave
Adenosine 2B Receptor Signaling Impairs Vaccine-Mediated Protection Against Pneumococcal Infection in Young Hosts by Blunting Neutrophil Killing of Antibody-Opsonized Bacteria
errVACCINES
IF3.4
err2025-04-15
err0
errOAAI
errSimmons, Shaunna R.; Lenhard, Alexsandra P.; Battaglia, Michael C.; Ghanem, Elsa N. Bou
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errSave
Sex-based difference in immune responses and efficacy of the pneumococcal conjugate vaccine
errJOURNAL OF LEUKOCYTE BIOLOGY
IF3.1
err2024-08-14
err0
errOAAI
errTchalla, Essi Y., I; Betadpur, Anagha; Khalil, Andrew Y.; Bhalla, Manmeet; Bou Ghanem, Elsa N.
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errSave
Activating A1 adenosine receptor signaling boosts early pulmonary neutrophil recruitment in aged mice in response to Streptococcus pneumoniae infection
errIMMUNITY & AGEING
IF5.6
err2024-06-05
err1
errOAAI
errSimmons, Shaunna R.; Herring, Sydney E.; Tchalla, Essi Y., I; Lenhard, Alexsandra P.; Bhalla, Manmeet; Ghanem, Elsa N. Bou
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errSave
CHIPing away at immunity: the role of clonal hematopoiesis of indeterminate potential in bacterial pneumonia
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-06-03
err0
errOAAI
errGhanem, Elsa N. Bou
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errSave
Mitochondrial ROS production by neutrophils is required for host antimicrobial function against Streptococcus pneumoniae and is controlled by A2B adenosine receptor signaling
errPLOS PATHOGENS
IF4.9
err2022-11-14
err14
errOAAI
errHerring, Sydney E.; Mao, Sovathiro; Bhalla, Manmeet; Tchalla, Essi Y., I; Kramer, Jill M.; Ghanem, Elsa N. Bou
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errSave
Liposomal Encapsulation of Polysaccharides (LEPS) as an Effective Vaccine Strategy to Protect Aged Hosts Against S. pneumoniae Infection
errFRONTIERS IN AGING
IF4.3
err2021-12-22
err4
errOAAI
errBhalla, Manmeet; Nayerhoda, Roozbeh; Tchalla, Essi Y. I.; Abamonte, Alexsandra; Park, Dongwon; Simmons, Shaunna R.; Pfeifer, Blaine A.; Bou Ghanem, Elsa N.
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errSave
Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
errVACCINES
IF3.4
err2021-06-02
err6
errOAAI
errWalkowski, William; Bassett, Justin; Bhalla, Manmeet; Pfeifer, Blaine A.; Ghanem, Elsa N. Bou
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errSave
Extracellular adenosine signaling reverses the age-driven decline in the ability of neutrophils to killStreptococcus pneumoniae
errAGING CELL
IF7.1
err2020-08-13
err21
errOAAI
errBhalla, Manmeet; Simmons, Shaunna R.; Abamonte, Alexsandra; Herring, Sydney E.; Roggensack, Sara E.; Bou Ghanem, Elsa N.
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errSave
Extended Polysaccharide Analysis within the Liposomal Encapsulation of Polysaccharides System
errMATERIALS
IF3.2
err2020-07-26
err3
errOAAI
errNayerhoda, Roozbeh; Park, Dongwon; Jones, Charles; Bou Ghanem, Elsa N.; Pfeifer, Blaine A.
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errSave
Neutrophils Are Required During Immunization With the Pneumococcal Conjugate Vaccine for Protective Antibody Responses and Host Defense Against Infection
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2020-05-11
err16
errOAAI
errTchalla, Essi Y., I; Bhalla, Manmeet; Wohlfert, Elizabeth A.; Ghanem, Elsa N. Bou
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errSave
Extracellular adenosine enhances the ability of PMNs to kill Streptococcus pneumoniae by inhibiting IL-10 production
errJOURNAL OF LEUKOCYTE BIOLOGY
IF3.1
err2020-02-04
err23
errOAAI
errSiwapornchai, Nalat; Lee, James N.; Tchalla, Essi Y., I; Bhalla, Manmeet; Yeoh, Jun Hui; Roggensack, Sara E.; Leong, John M.; Ghanem, Elsa N. Bou
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errSave
Pneumolysin Induces 12-Lipoxygenase-Dependent Neutrophil Migration during Streptococcus pneumoniae Infection
errJOURNAL OF IMMUNOLOGY
IF3.4
err2020-01-01
err24
errOAAI
errAdams, Walter; Bhowmick, Rudra; Ghanem, Elsa N. Bou; Wade, Kristin; Shchepetov, Mikhail; Weiser, Jeffrey N.; McCormick, Beth A.; Tweten, Rodney K.; Leong, John M.
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errSave
mSphere of Influence: Adenosine in Host Defense against Bacterial Pneumonia-Friend or Foe?
errMSPHERE
IF3.1
err2019-08-28
err2
errOAAI
errGhanem, Elsa N. Bou
errShare
errSave
Nasopharyngeal exposure to Streptococcus pneumoniae induces extended age-dependent protection against pulmonary infection mediated by antibodies and CD138+ cells (vol 200, pg 3739, 2018)
errJOURNAL OF IMMUNOLOGY
IF3.4
err2018-12-01
err0
errOAAI
errGhanem, Bou E. N.; Maung, N. H. T.; Siwapornchai, N.; Goodwin, A. E.; Clark, S.; Munoz-Elias, E. J.; Camilli, A.; Gerstein, R. M.; Leong, J. M.
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errSave
Nasopharyngeal Exposure to Streptococcus pneumoniae Induces Extended Age-Dependent Protection against Pulmonary Infection Mediated by Antibodies and CD138+ Cells
errJOURNAL OF IMMUNOLOGY
IF3.4
err2018-06-01
err17
errOAAI
errGhanem, Elsa N. Bou; Maung, Nang H. Tin; Siwapornchai, Nalat; Goodwin, Aaron E.; Clark, Stacie; Munoz-Elias, Ernesto J.; Camilli, Andrew; Gerstein, Rachel M.; Leong, John M.
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errSave
Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil Recruitment
errPLOS PATHOGENS
IF4.9
err2015-08-27
err75
errOAAI
errGhanem, Elsa N. Bou; Clark, Stacie; Roggensack, Sara E.; McIver, Sally R.; Alcaide, Pilar; Haydon, Philip G.; Leong, John M.
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errSave
The α-Tocopherol Form of Vitamin E Reverses Age-Associated Susceptibility to Streptococcus pneumoniae Lung Infection by Modulating Pulmonary Neutrophil Recruitment
errJOURNAL OF IMMUNOLOGY
IF3.4
err2015-02-01
err73
errOAAI
errGhanem, Elsa N. Bou; Clark, Stacie; Du, Xiaogang; Wu, Dayong; Camilli, Andrew; Leong, John M.; Meydani, Simin N.
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errSave
Systemic Disease during Streptococcus pneumoniae Acute Lung Infection Requires 12-Lipoxygenase-Dependent Inflammation
errJOURNAL OF IMMUNOLOGY
IF3.4
err2013-11-15
err72
errOAAI
errBhowmick, Rudra; Maung, Nang H. Tin; Hurley, Bryan P.; Ghanem, Elsa Bou; Gronert, Karsten; McCormick, Beth A.; Leong, John M.
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errSave

Research Directions

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Co-authors
Cooperation Journals
J
Jeffrey N. Weiser
H-index: 86 · Papers: 272
A
Andrew Camilli
H-index: 83 · Papers: 234
P
Philip G. Haydon
H-index: 79 · Papers: 214
S
Simin Nikbin Meydani
H-index: 77 · Papers: 494
J
John M. Leong
H-index: 66 · Papers: 241
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