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SaveGain of chromosome 17 is an early genetic abnormality in neuroblastoma with PPM1D emerging as a strong candidate oncogene driving tumor progression
Milosevic, Jelena; Fransson, Susanne; Svensson, Johanna; Otte, Jorg; Olsen, Thale K.; Sveinbjornsson, Baldur; Hertwig, Falk; Bartenhagen, Christoph; Abel, Frida; Reinsbach, Susanne E.; Djos, Anna; Javanmardi, Niloufar; Shi, Yao; Hehir-Kwa, Jane Y.; Mensenkamp, Arjen; Tytgat, Godelieve AM.; Holmberg, Johan; Molenaar, Jan J.; Jongmans, Marjolijn; Fischer, Matthias; Baryawno, Ninib; Gisselsson, David; Martinsson, Tommy; Kogner, Per; Johnsen, John Inge Share Save Share Save Personalized circulating tumor DNA analysis for sensitive disease monitoring and detection of relapse in neuroblastomaRahmqvist, Ida; Engstrom, Enya; Mellstrom, Elisabeth; Ibrahim, Raghda R.; Pujol-Calderon, Fani; Rudin, Agnes Dahlstrand; Redfors, Anna Ordqvist; Rostamzadeh, Niki; Di Rienzo, Rita; Franssila, Wilma; Khashan, Robert; Xylander, Moe; Karlsson, Christin; Ek, Torben; Andersson, Daniel; Osterlund, Tobias; Gaarder, Jennie; Fagman, Henrik; Fransson, Susanne; Martinsson, Tommy; Stahlberg, Anders; Dalin, Martin Share Save Heterogeneous SSTR2 target expression and a novel KIAA1549::BRAF fusion clone in a progressive metastatic lesion following 177Lutetium-DOTATATE molecular radiotherapy in neuroblastoma: a case reportPark, Se Whee Sammy; Fransson, Susanne; Sundquist, Fredrik; Nilsson, Joachim N.; Gryback, Per; Wessman, Sandra; Stromgren, Jacob; Djos, Anna; Fagman, Henrik; Sjoegren, Helene; Georgantzi, Kleopatra; Herold, Nikolas; Kogner, Per; Granberg, Dan; Gaze, Mark N.; Martinsson, Tommy; Karlsson, Kasper; Stenman, Jakob J. E. Share Save Joint single-cell genetic and transcriptomic analysis reveal pre-malignant SCP-like subclones in human neuroblastomaOlsen, Thale K.; Otte, Jorg; Mei, Shenglin; Embaie, Bethel Tesfai; Kameneva, Polina; Cheng, Huaitao; Gao, Teng; Zachariadis, Vasilios; Tsea, Ioanna; Bjorklund, Asa; Kryukov, Emil; Hou, Ziyi; Johansson, Anna; Sundstrom, Erik; Martinsson, Tommy; Fransson, Susanne; Stenman, Jakob; Fard, Shahrzad Shirazi; Johnsen, John Inge; Kogner, Per; Adameyko, Igor; Enge, Martin; Kharchenko, Peter V.; Baryawno, Ninib Share Save Altered methylation of imprinted genes in neuroblastoma: implications for prognostic refinementSuman, Medha; Lofgren, Maja; Fransson, Susanne; Yousuf, Jewahri Idris; Svensson, Johanna; Djos, Anna; Martinsson, Tommy; Kogner, Per; Kling, Teresia; Caren, Helena Share Save Loss of Chromosome Y in Neuroblastoma Is Associated With High-Risk Disease, 11q-Deletion, and Telomere MaintenanceDjos, Anna; Svensson, Johanna; Gaarder, Jennie; Umapathy, Ganesh; Nilsson, Staffan; Ek, Torben; Vogt, Hartmut; Georgantzi, Kleopatra; Ora, Ingrid; Trager, Catarina; Kogner, Per; Martinsson, Tommy; Fransson, Susanne Share Save Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors - a nationwide, prospective Swedish studyTesi, Bianca; Robinson, Kristina Lagerstedt; Abel, Frida; Stahl, Teresita Diaz de; Orrsjoe, Sara; Poluha, Anna; Hellberg, Maria; Wessman, Sandra; Samuelsson, Sofie; Frisk, Tony; Vogt, Hartmut; Henning, Karin; Sabel, Magnus; Ek, Torben; Pal, Niklas; Nyman, Per; Giraud, Geraldine; Wille, Joakim; Pronk, Cornelis Jan; Noren-Nystroem, Ulrika; Borssen, Magnus; Fili, Maria; Stalhammar, Gustav; Herold, Nikolas; Tettamanti, Giorgio; Maya-Gonzalez, Carolina; Arvidsson, Linda; Rosen, Anna; Ekholm, Katja; Kuchinskaya, Ekaterina; Hallbeck, Anna-Lotta; Nordling, Margareta; Palmebaeck, Pia; Kogner, Per; Smoler, Gunilla Kanter; Laehteenmaeki, Paeivi; Fransso, Susanne; Martinsson, Tommy; Shamik, Alia; Mertens, Fredrik; Rosenquist, Richard; Wirta, Valtteri; Tham, Emma; Grillner, Pernilla; Sandgren, Johanna; Ljungman, Gustaf; Gisselsson, David; Taylan, Fulya; Nordgren, Ann Share Save METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastomaVaid, Roshan; Thombare, Ketan; Mendez, Akram; Burgos-Panadero, Rebeca; Djos, Anna; Jachimowicz, Daniel; Lundberg, Kristina Ihrmark; Bartenhagen, Christoph; Kumar, Navinder; Tummler, Conny; Sihlbom, Carina; Fransson, Susanne; Johnsen, John Inge; Kogner, Per; Martinsson, Tommy; Fischer, Matthias; Mondal, Tanmoy Share Save Share Save Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma subgroupMartinez-Monleon, Angela; Oberg, Hanna Kryh; Gaarder, Jennie; Berbegall, Ana P.; Javanmardi, Niloufar; Djos, Anna; Ussowicz, Marek; Taschner-Mandl, Sabine; Ambros, Inge M.; Ora, Ingrid; Sandstedt, Bengt; Beiske, Klaus; Ladenstein, Ruth; Noguera, Rosa; Ambros, Peter F.; Murkes, Lena Gordon; Ljungman, Gustaf; Kogner, Per; Fransson, Susanne; Martinsson, Tommy Share Save Share Save ALK ligand ALKAL2 potentiates MYCN-driven neuroblastoma in the absence of ALK mutationBorenas, Marcus; Umapathy, Ganesh; Lai, Wei-Yun; Lind, Dan E.; Witek, Barbara; Guan, Jikui; Mendoza-Garcia, Patricia; Masudi, Tafheem; Claeys, Arne; Chuang, Tzu-Po; El Wakil, Abeer; Arefin, Badrul; Fransson, Susanne; Koster, Jan; Johansson, Mathias; Gaarder, Jennie; Van den Eynden, Jimmy; Hallberg, Bengt; Palmer, Ruth H. Share Save Share Save 11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in NeuroblastomaSiaw, Joachim Tetteh; Javanmardi, Niloufar; Van den Eynden, Jimmy; Lind, Dan Emil; Fransson, Susanne; Martinez-Monleon, Angela; Djos, Anna; Sjoberg, Rose-Marie; Ostensson, Malin; Caren, Helena; Troen, Gunhild; Beiske, Klaus; Berbegall, Ana P.; Noguera, Rosa; Lai, Wei-Yun; Kogner, Per; Palmer, Ruth H.; Hallberg, Bengt; Martinsson, Tommy Share Save Analysis of ALK, MYCN, and the ALK ligand ALKAL2 (FAM150B/AUGα) in neuroblastoma patient samples with chromosome arm 2p rearrangementsJavanmardi, Niloufar; Fransson, Susanne; Djos, Anna; Umapathy, Ganesh; Ostensson, Malin; Milosevic, Jelena; Borenaes, Marcus; Hallberg, Bengt; Kogner, Per; Martinsson, Tommy; Palmer, Ruth H. Share Save Share Save Share Save Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in NeuroblastomaBraekeveldt, Noemie; von Stedingk, Kristoffer; Fransson, Susanne; Martinez-Monleon, Angela; Lindgren, David; Axelson, Hakan; Levander, Fredrik; Willforss, Jakob; Hansson, Karin; Ora, Ingrid; Backman, Torbjorn; Borjesson, Anna; Beckman, Siv; Esfandyari, Javanshir; Berbegall, Ana P.; Noguera, Rosa; Karlsson, Jenny; Koster, Jan; Martinsson, Tommy; Gisselsson, David; Pahlman, Sven; Bexell, Daniel Share Save 
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