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ITCC-P4, a preclinical proof-of-concept drug testing platform as a tool for pharmacological screening in pediatric tumor models Indersie, Emilie; Branchereau, Sophie; Fresneau, Brice; Chardot, Christophe; Surdez, Didier; Saint-Charles, Alexandra; da Costa, Maria Eugenia Marques; Carcaboso, Angel M.; Scotlandi, Katia; Moro, Massimo; Kovar, Heinrich; Klusmann, Jan-Henning; Debatin, Klaus-Michael; Bomken, Simon; Chesler, Louis; Jones, Chris; Schafer, Beat; Wachtel, Marco; Gojo, Johannes; Berger, Walter; Guttke, Christina; Hattersley, Maureen; Colland, Frederic; Strougo, Ashley; Gurgen, Dennis; Hoffmann, Jens; Schueler, Julia; Aviles, Pablo M.; Guillen, Maria Jose; Federico, Aniello; Gopisetty, Apurva; Wierzbinska, Justyna Anna; Schlicker, Andreas; Colombetti, Sara; Heidenreich, Olaf; Iradier, Fatima; Huebener, Nicole; Jager, Natalie; Koster, Jan; Kool, Marcel; Schleiermacher, Gudrun; Molenaar, Jan J.; Geoerger, Birgit; Shields, David J.; Caron, Hubert N.; Stancato, Louis F.; Pfister, Stefan M.; Vassal, Gilles; Rief, Eva-Maria; Deas, Olivier Share Save
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Decreased eukaryotic initiation factors expression upon temozolomide treatment-potential novel implications for eIFs in glioma therapy Krassnig, Stefanie; Leber, Stefan L.; Orthmann, Andrea; Golob-Schwarzl, Nicole; Huber, Heinrich Johann; Wohlrab, Christina; Skofler, Christina; Pennauer, Mirjam; Raicht, Andrea; Birkl-Toeglhofer, Anna Maria; Naumann, Michael; Mahdy-Ali, Kariem; von Campe, Gord; Leoni, Marlene; Alcaniz, Joshua; Hoffmann, Jens; Waelchli, Thomas; Weis, Serge; Benesch, Martin; Haybaeck, Johannes Share Save
A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer Kendzia, Sandra; Franke, Susanne; Kroehler, Tarek; Golob-Schwarzl, Nicole; Schweiger, Caroline; Toeglhofer, Anna M.; Skofler, Christina; Uranitsch, Stefan; El-Heliebi, Amin; Fuchs, Julia; Punschart, Andreas; Stiegler, Philipp; Keil, Marlen; Hoffmann, Jens; Henderson, David; Lehrach, Hans; Yaspo, Marie-Laure; Reinhard, Christoph; Schaefer, Reinhold; Keilholz, Ulrich; Regenbrecht, Christian; Schicho, Rudolf; Fickert, Peter; Lax, Sigurd F.; Erdmann, Frank; Schulz, Marcel H.; Kiemer, Alexandra K.; Haybaeck, Johannes; Kessler, Sonja M. Share Save
Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures Alcaniz, Joshua; Winkler, Lars; Dahlmann, Mathias; Becker, Michael; Orthmann, Andrea; Haybaeck, Johannes; Krassnig, Stefanie; Skofler, Christina; Kratzsch, Tobias; Kuhn, Susanne A.; Joedicke, Andreas; Linnebacher, Michael; Fichtner, Iduna; Walther, Wolfgang; Hoffmann, Jens Share Save
Patient-derived xenograft (PDX) and corresponding cell line models from glioblastoma for drug development, immuno-oncology and translational research Alcaniz, Joshua; Winkler, Lars; Stecklum, Maria; Wieland, Hagen; Siegert, Antje; Becker, Michael; Brzezicha, Bernadette; Walther, Wolfgang; Hoffmann, Jens Share Save
An in vivo platform of pre-characterized renal cell carcinoma (RCC) patient- derived xenograft models allows the preclinical evaluation of patient-tailored intervention strategies Kobelt, Dennis; Gurgen, Dennis; Becker, Michael; Dahlmann, Mathias; Flechsig, Susanne; Schaeffeler, Elke; Buttner, Florian A.; Schmees, Christian; Bohnert, Regina; Bedke, Jens; Schwab, Matthias; Wendler, Johann J.; Schostak, Martin; Jandrig, Burkhard; Walther, Wolfgang; Hoffmann, Jens Share Save
The ITCC-P4 sustainable platform of fully characterized PDXs supports the preclinical proof-of-concept drug testing of high-risk pediatric tumor models Federico, Aniello; Gopisetty, Apurva; Surdez, Didier; Iddir, Yasmine; Saint-Charles, Alexandra; Wierzbinska, Justyna; Schlicker, Andreas; Volckmann, Richard; Zwijnenburg, Danny; Colombetti, Sara; Heidenreich, Olaf; Iradier, Fatima; Kovar, Heinrich; Klusmann, Jan-Henning; Debatin, Klaus-Michael; Bomken, Simon; Guttke, Christina; Hattersley, Maureen M.; Colland, Frederic; Strougo, Ashley; Guillen, Maria Jose; Chesler, Louis; Jones, Chris; da Costa, Maria Eugenia Marques; Scotlandi, Katia; Moro, Massimo; Schafer, Beat; Wachtel, Marco; Gojo, Johannes; Berger, Walter; Carcaboso, Angel Montero; Gurgen, Dennis; Hoffmann, Jens; Indersie, Emilie; Cairo, Stefano; Schueler, Julia; Huebener, Nicole; Schulte, Johannes H.; Molenaar, Jan J.; Geoerger, Birgit; Shields, David J.; Caron, Hubert N.; Vassal, Gilles; Stancato, Lou F.; Pfister, Stefan M.; Jager, Natalie; Koster, Jan; Kool, Marcel; Schleiermacher, Gudrun Share Save
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A Molecularly Characterized Preclinical Platform of Subcutaneous Renal Cell Carcinoma (RCC) Patient-Derived Xenograft Models to Evaluate Novel Treatment Strategies Guergen, Dennis; Becker, Michael; Dahlmann, Mathias; Flechsig, Susanne; Schaeffeler, Elke; Buettner, Florian A.; Schmees, Christian; Bohnert, Regina; Bedke, Jens; Schwab, Matthias; Wendler, Johann J.; Schostak, Martin; Jandrig, Burkhard; Walther, Wolfgang; Hoffmann, Jens Share Save
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Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models Dahlmann, Mathias; Gambara, Guido; Brzezicha, Bernadette; Popp, Oliver; Pachmayr, Eva; Wedeken, Lena; Pflaume, Alina; Mokritzkij, Margarita; Guel-Klein, Safak; Brandl, Andreas; Schweiger-Eisbacher, Caroline; Mertins, Philipp; Hoffmann, Jens; Keilholz, Ulrich; Walther, Wolfgang; Regenbrecht, Christian; Rau, Beate; Stein, Ulrike Share Save
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