Not logged inInhibition of tau neuronal internalization using anti-tau single domain antibodies
Danis, Clement; Dupre, Elian; Bouillet, Thomas; Denechaud, Marine; Lefebvre, Camille; Nguyen, Marine; Mortelecque, Justine; Cantrelle, Francois-Xavier; Rain, Jean-Christophe; Hanoulle, Xavier; Colin, Morvane; Landrieu, Isabelle .png)
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SaveA selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered proteinMortelecque, Justine; Zejneli, Orgeta; Begard, Severine; Simoes, Margarida C.; Cantrelle, Francois-Xavier; ElHajjar, Lea; Hanoulle, Xavier; Nguyen, Marine; Rain, Jean-Christophe; Landrieu, Isabelle; Gomes, Claudio M.; Buee, Luc; Danis, Clement; Colin, Morvane; Dupre, Elian Share Save Development of a V5-tag-directed nanobody and its implementation as an intracellular biosensor of GPCR signalingZeghal, Manel; Matte, Kevin; Venes, Angelica; Patel, Shivani; Laroche, Genevieve; Sarvan, Sabina; Joshi, Monika; Rain, Jean-Christophe; Couture, Jean-Francois; Giguere, Patrick M. Share Save AAC-11 survival pathways as therapeutic target in cancer: AAC-11 leucine-zipper domain derived peptides exert potent antitumor effects and exhibit favorable stability, pharmacokinetic and toxicology profilesJeammet, Louise; Adiceam, Emile; Habault, Justine; Kaci, Anna; Berrou, Jeannig; Dupont, Melanie; Thonnart, Nicolas; Pasquereau-Kotula, Ewa; Marie-Cardine, Anne; Bensussan, Armand; Pla, Marika; Dombret, Herve; Gardin, Claude; Bagot, Martine; Rain, Jean-Christophe; Sicard, Helene; Tiollier, Jerome; Braun, Thorsten; Poyet, Jean-Luc Share Save Share Save Share Save Share Save Secretion of VGF relies on the interplay between LRRK2 and post-Golgi v-SNAREsFilippini, Francesca; Nola, Sebastien; Zahraoui, Ahmed; Roger, Kevin; Esmaili, Mansoore; Sun, Ji; Wojnacki, Jose; Vlieghe, Anais; Bun, Philippe; Blanchon, Stephanie; Rain, Jean-Christophe; Taymans, Jean-Marc; Chartier-Harlin, Marie-Christine; Guerrera, Chiara; Galli, Thierry Share Save Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's diseaseViard, Julia; Loe-Mie, Yann; Daudin, Rachel; Khelfaoui, Malik; Plancon, Christine; Boland, Anne; Tejedor, Francisco; Huganir, Richard L.; Kim, Eunjoon; Kinoshita, Makoto; Liu, Guofa; Haucke, Volker; Moncion, Thomas; Yu, Eugene; Hindie, Valerie; Blehaut, Henri; Mircher, Clotilde; Herault, Yann; Deleuze, Jean-Francois; Rain, Jean-Christophe; Simonneau, Michel; Lepagnol-Bestel, Aude-Marie Share Save Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragmentDanis, Clement; Dupre, Elian; Zejneli, Orgeta; Caillierez, Raphaelle; Arrial, Alexis; Begard, Severine; Mortelecque, Justine; Eddarkaoui, Sabiha; Loyens, Anne; Cantrelle, Francois-Xavier; Hanoulle, Xavier; Rain, Jean-Christophe; Colin, Morvane; Buee, Luc; Landrieu, Isabelle Share Save Fr-PPIChem: An Academic Compound Library Dedicated to Protein- Protein InteractionsBosc, Nicolas; Muller, Christophe; Hoffer, Laurent; Lagorce, David; Bourg, Stephane; Derviaux, Carine; Gourdel, Marie-Edith; Rain, Jean-Christophe; Miller, Thomas W.; Villoutreix, Bruno O.; Miteva, Maria; Bonnet, Pascal; Morelli, Xavier; Sperandio, Olivier; Roche, Philippe Share Save Single Domain Antibody Fragments as New Tools for the Detection of Neuronal Tau Protein in Cells and in Mice StudiesDupre, Elian; Danis, Clement; Arrial, Alexis; Hanoulle, Xavier; Homa, Megane; Cantrelle, Francois-Xavier; Merzougui, Hamida; Colin, Morvane; Rain, Jean-Christophe; Buee, Luc; Landrieu, Isabelle Share Save Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampusGranno, Simone; Nixon-Abell, Jonathon; Berwick, Daniel C.; Tosh, Justin; Heaton, George; Almudimeegh, Sultan; Nagda, Zenisha; Rain, Jean-Christophe; Zanda, Manuela; Plagnol, Vincent; Tybulewicz, Victor L. J.; Cleverley, Karen; Wiseman, Frances K.; Fisher, Elizabeth M. C.; Harvey, Kirsten Share Save The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperonesMaurizy, Chloe; Quinternet, Marc; Abel, Yoann; Verheggen, Celine; Santo, Paulo E.; Bourguet, Maxime; Paiva, Ana C. F.; Bragantini, Benoit; Chagot, Marie-Eve; Robert, Marie-Cecile; Abeza, Claire; Fabre, Philippe; Fort, Philippe; Vandermoere, Franck; Sousa, Pedro M. F.; Rain, Jean-Christophe; Charpentier, Bruno; Cianferani, Sarah; Bandeiras, Tiago M.; Pradet-Balade, Berengere; Manival, Xavier; Bertrand, Edouard Share Save Risk factor gene BIN1 induces late onset Alzheimer disease presymptomatic phenotypes in a BAC transgenic mouse modelMarechal, D.; Daudin, R.; Bourg, N.; Loe-Mie, Y.; Potier, B.; Dutar, P.; Viard, J.; Lepagnol-Bestel, A.; Sartori, M.; Hindie, V.; Birling, M.; Pavlovic, G.; Dupuis, G.; Fort, S. Leveque; Laporte, J.; Rain, J.; Simonneau, M.; Herault, Y. Share Save The N-terminal domain of Filaggrin 2 co-localizes, binds to and activates the Skin aspartic acid protease in the epidermis of human skinDonovan, M.; Thomas-Collignon, A.; Simonetti, L.; Desbouis, S.; Collin-Djangone, C.; Reverdy, C.; Rain, J.; Formstecher, E.; Bernard, D. Share Save NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodiesMoutel, Sandrine; Bery, Nicolas; Bernard, Virginie; Keller, Laura; Lemesre, Emilie; de Marco, Ario; Ligat, Laetitia; Rain, Jean-Christophe; Favre, Gilles; Olichon, Aurelien; Perez, Franck Share Save Share Save Share Save Share Save 
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