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Lea Altendorf

Research Institute Children's Cancer Center Hamburg

3H-index
24Paper Count
52Citation Count
Published Papers 15
Publication Date
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Overactivation of SHH signaling induces a cascade of dedifferentiation and oncogenesis in a new mouse model for choroid plexus carcinoma
errActa Neuropathologica Communications
IF5.7
err2026-08-21
err0
errOAAI
errLevke-Sophie Peter; Lea Altendorf; Karoline Hack; Vanessa Thaden; Carolin Göbel; Beatrix Mahnke; Christian Krebs; Saskia-L. Jauch-Speer; Uwe R. Kordes; Denise Obrecht-Sturm; Christian Thomas; Ulrich Schüller; Melanie Schoof
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Cover Image, Volume 45, Issue 12
errCancer Communications
IF24.9
err2026-07-27
err0
errOAAI
errNicole C. Riedel; Carolin Walter; Flavia W. de Faria; Lea Altendorf; Paula Aust; Carolin Göbel; Archana Verma; Annika Ballast; Ivan Bedzhov; Rajanya Roy; Daniel Münter
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errSave
Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models
errNature Genetics
IF29
err2025-12-11
err0
errOAAI
errMelanie Schoof; Tuyu Zheng; Martin Sill; Roland Imle; Alessia Cais; Lea Altendorf; Alicia Fürst; Nina Hofmann; Kati Ernst; Dominik Vonficht; Kenneth Chun-Ho Chan; Tim Holland-Letz; Andreas Postlmayr; Ryo Shiraishi; Wanchen Wang; Alaide Morcavallo; Michael Spohn; Carolin Göbel; Judith Niesen; Levke-Sophie Peter; Franck Bourdeaut; Zhi-Yan Han; Yanxin Pei; Najiba Murad; Fredrik J. Swartling; Jessica Taylor; Monika Yadav; Garrett R. Gibson; Richard J. Gilbertson; Matthias Dottermusch; Rajanya Roy; Kornelius Kerl; Rainer Glass; Jiying Cheng; Martin A. Horstmann; Gerrit Wolters-Eisfeld; Haotian Zhao; Dominik Sturm; Viveka Nand Yadav; Louis Chesler; Simon Haas; William A. Weiss; Paul A. Northcott; Lena M. Kutscher; Ana Guerreiro Stucklin; Olivier Ayrault; Julia E. Neumann; Daisuke Kawauchi; David T. W. Jones; Kristian Pajtler; Ana Banito; Stefan M. Pfister; Ulrich Schüller; Marc Zuckermann
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errSave
In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery
errCancer Communications
IF24.9
err2025-11-02
err0
errOAAI
errNicole C. Riedel; Carolin Walter; Flavia W. de Faria; Lea Altendorf; Paula Aust; Carolin Göbel; Archana Verma; Annika Ballast; Ivan Bedhzov; Rajanya Roy; Daniel Münter; Erik Schüftan; Thomas K. Albert; Claudia Rössig; Pascal Johann; Barbara von Zezschwitz; Sarah Sandmann; Julian Varghese; Christian Thomas; Ulrich Schüller; Jan M. Bruder; Kornelius Kerl
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errSave
Single-cell transcriptomics link gene expression signatures to clinicopathological features of gonadotroph and lactotroph PitNET
errJOURNAL OF TRANSLATIONAL MEDICINE
IF7.5
err2024-11-15
err0
errOAAI
errPotthoff, T. Elise; Walter, Carolin; Jeising, Daniela; Muenter, Daniel; Verma, Archana; Molina, Eric Suero; Stummer, Walter; Dugas, Martin; Hartmann, Wolfgang; Dottermusch, Matthias; Altendorf, Lea; Schueller, Ulrich; Scheuermann, Sophia; Seitz, Christian; Albert, Thomas K.; Kerl, Kornelius
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SINGLE-CELL RNA (SCRNA) SEQUENCING OF PAIRED PRIMARY AND RECURRENT ATYPICAL TERATOID/RHABDOID TUMORS (AT/RT) REVEALED MOLECULAR DIFFERENCES AND THERAPY-RESISTANT PRIMARY TUMOR CELLS
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errAltendorf, Lea; Roy, Rajanya; de Faria, Flavia W.; Hack, Karoline; Koch, Arend; Schuhmann, Martin U.; Hauser, Peter; Johann, Pascal D.; Hasselblatt, Martin; Kerl, Kornelius; Fruehwald, Michael C.; Schueller, Ulrich
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errSave
Medulloblastoma in children with Fanconi anemia: Association with FA-D1/FA-N, SHH type and poor survival independent of treatment strategies
errNEURO-ONCOLOGY
IF13.4
err2024-06-26
err0
PREAI
errSoenksen, Marthe; Obrecht-Sturm, Denise; Hernaiz Driever, Pablo; Sauerbrey, Axel; Graf, Norbert; Kontny, Udo; Reimann, Christian; Langhein, Mina; Kordes, Uwe R.; Schwarz, Rudolf; Obser, Tobias; Boschann, Felix; Schueller, Ulrich; Altendorf, Lea; Goschzik, Tobias; Pietsch, Torsten; Mynarek, Martin; Rutkowski, Stefan
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DECODING TUMOR-NEURONAL COMMUNICATION IN PEDIATRIC BRAIN TUMORS: INSIGHTS FROM ETMR 3D MODEL REVEALING MECHANO-SIGNALING DYNAMICS AND THERAPEUTIC OPPORTUNITIES
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errSterbies, Nicolas; de Faria, Flavia Watusi; Riedel, Nicole; Muenter, Daniel; Altendorf, Lea; Goebel, Carolin; Inserte, Clara; Roy, Rajanya; Thomas, Christian; Schueller, Ulrich; Bruder, Jan M.; Kerl, Kornelius
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IN VITRO MODELING OF AND AUTOMATED DRUG SCREENING IN EMBRYONAL BRAIN TUMORS USING TUMOR-BRAIN ORGANOIDS
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errRiedel, Nicole C.; Walter, Carolin; Aust, Paula; de Faria, Flavia; Altendorf, Lea; Goebel, Carolin; Verma, Archana; Roy, Rajanya; Thomas, Christian; Schueller, Ulrich; Bruder, Jan M.; Kerl, Kornelius
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errSave
MEDULLOBLASTOMA IN CHILDREN WITH FANCONI ANEMIA: ASSOCIATION WITH FA-D1/FA-N, SHH TYPE AND POOR SURVIVAL INDEPENDENT OF TREATMENT STRATEGIES
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errSoenksen, Marthe; Obrecht-Sturm, Denise; Driever, Pablo Hernaiz; Sauerbrey, Axel; Graf, Norbert; Kontny, Udo; Reimann, Christian; Kordes, Uwe; Schwarz, Rudolf; Obser, Tobias; Boschann, Felix; Schueller, Ulrich; Altendorf, Lea; Goschzik, Tobias; Pietsch, Torsten; Mynarek, Martin; Rutkowski, Stefan
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A NOVEL MOUSE MODEL OF CHOROID PLEXUS CARCINOMA UNRAVELS SEQUENTIAL DEDIFFERENTIATION OF HINDBRAIN CHOROID PLEXUS TISSUE AND REVEALS NEW THERAPEUTIC PROSPECTS
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errPeter, Levke-Sophie; Altendorf, Lea; Hack, Karoline; Thaden, Vanessa; Goebel, Carolin; Krebs, Christian F.; Jauch-Speer, Saskia-Larissa; Kordes, Uwe R.; Obrecht-Sturm, Denise; Thomas, Christian; Schueller, Ulrich; Schoof, Melanie
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Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology
errACTA NEUROPATHOLOGICA
IF9.3
err2024-01-24
err1
errOAAI
errGoedicke, Swenja; Kresbach, Catena; Ehlert, Max; Obrecht, Denise; Altendorf, Lea; Hack, Karoline; von Hoff, Katja; Caren, Helena; Melcher, Viktoria; Kerl, Kornelius; Englinger, Bernhard; Filbin, Mariella; Pajtler, Kristian W.; Gojo, Johannes; Pietsch, Torsten; Rutkowski, Stefan; Schueller, Ulrich
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Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics
errACTA NEUROPATHOLOGICA
IF9.3
err2023-07-14
err7
errOAAI
errJohann, Pascal D.; Altendorf, Lea; Efremova, Emma-Maria; Holsten, Till; Steinbuegl, Mona; Nemes, Karolina; Eckhardt, Alicia; Kresbach, Catena; Bockmayr, Michael; Koch, Arend; Haberler, Christine; Antonelli, Manila; DeSisto, John; Schuhmann, Martin U.; Hauser, Peter; Siebert, Reiner; Bens, Susanne; Kool, Marcel; Green, Adam L.; Hasselblatt, Martin; Fruehwald, Michael C.; Schueller, Ulrich
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Atypical neurofibromas reveal distinct epigenetic features with proximity to benign peripheral nerve sheath tumor entities
errNEURO-ONCOLOGY
IF13.4
err2023-03-02
err9
errOAAI
errKresbach, Catena; Dottermusch, Matthias; Eckhardt, Alicia; Ristow, Inka; Paplomatas, Petros; Altendorf, Lea; Wefers, Annika K.; Bockmayr, Michael; Belakhoua, Sarra; Tran, Ivy; Pohl, Lara; Neyazi, Sina; Bode, Helena; Farschtschi, Said; Well, Lennart; Friedrich, Reinhard E.; Reuss, David; Snuderl, Matija; Hagel, Christian; Mautner, Victor-Felix; Schueller, Ulrich
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Generation of new transgenic SMARCA4-deficient mouse models results in neuromuscular weakness and paralysis of limbs
errBRAIN PATHOLOGY
IF6.2
err2022-12-29
err0
errOAAI
errNeyazi, Sina; Altendorf, Lea; Schwetje, Dora; Goebel, Carolin; Schoof, Melanie; Holdhof, Doerthe; Schueller, Ulrich
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Research Directions

No research directions
Co-authors
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