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SaveShare Save Share Save Share Save Share Save Share Save Share Save Share Save Carrier-free mRNA vaccine induces robust immunity against SARS-CoV-2 in mice and non-human primates without systemic reactogenicity
Abbasi, Saed; Matsui-Masai, Miki; Yasui, Fumihiko; Hayashi, Akimasa; Tockary, Theofilus A.; Mochida, Yuki; Akinaga, Shiro; Kohara, Michinori; Kataoka, Kazunori; Uchida, Satoshi Share Save Share Save Poly(ethylene Glycol) (PEG)-OligoRNA Hybridization to mRNA Enables Fine-Tuned Polyplex PEGylation for Spleen-Targeted mRNA DeliverySuzuki, Miki; Mochida, Yuki; Hori, Mao; Hayashi, Akimasa; Toh, Kazuko; Tockary, Theofilus A.; Liu, Xueying; Marx, Victor; Yokoo, Hidetomo; Miyata, Kanjiro; Oba, Makoto; Uchida, Satoshi Share Save Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide DeliveryYum, Jongmin; Aulia, Fadlina; Kamiya, Keisuke; Hori, Mao; Qiao, Nan; Kim, Beob Soo; Naito, Mitsuru; Ogura, Satomi; Nagata, Tetsuya; Yokota, Takanori; Uchida, Satoshi; Obika, Satoshi; Kim, Hyun Jin; Miyata, Kanjiro Share Save Ionizable Polymeric Micelles with Phenylalanine Moieties Enhance Intracellular Delivery of Self-Replicating RNA for Long-Lasting Protein Expression In VivoMixich, Lucas; Boonstra, Eger; Masuda, Keita; Li, Shang-Wei; Nakashima, Yuki; Meng, Fanlu; Sakata, Momoko; Goda, Tatsuro; Uchida, Satoshi; Cabral, Horacio Share Save Share Save Share Save Comb- structured mRNA vaccine tethered with short double- stranded RNA adjuvants maximizes cellular immunity for cancer treatmentTockary, Theofilus A.; Abbasi, Saed; Matsui-Masai, Miki; Hayashi, Akimasa; Yoshinaga, Naoto; Boonstra, Eger; Wang, Zheng; Fukushima, Shigeto; Kataoka, Kazunori; Uchida, Satoshi Share Save Cap analogs with a hydrophobic photocleavable tag enable facile purification of fully capped mRNA with various cap structuresInagaki, Masahito; Abe, Naoko; Li, Zhenmin; Nakashima, Yuko; Acharyya, Susit; Ogawa, Kazuya; Kawaguchi, Daisuke; Hiraoka, Haruka; Banno, Ayaka; Meng, Zheyu; Tada, Mizuki; Ishida, Tatsuma; Lyu, Pingxue; Kokubo, Kengo; Murase, Hirotaka; Hashiya, Fumitaka; Kimura, Yasuaki; Uchida, Satoshi; Abe, Hiroshi Share Save Block catiomers with flanking hydrolyzable tyrosinate groups enhance in vivo mRNA delivery via π-π stacking-assisted micellar assemblyYang, Wenqian; Miyazaki, Takuya; Nakagawa, Yasuhiro; Boonstra, Eger; Masuda, Keita; Nakashima, Yuki; Chen, Pengwen; Mixich, Lucas; Barthelmes, Kevin; Matsumoto, Akira; Mi, Peng; Uchida, Satoshi; Cabral, Horacio Share Save Complete Chemical Synthesis of Minimal Messenger RNA by Efficient Chemical Capping ReactionAbe, Naoko; Imaeda, Akihiro; Inagaki, Masahito; Li, Zhenmin; Kawaguchi, Daisuke; Onda, Kaoru; Nakashima, Yuko; Uchida, Satoshi; Hashiya, Fumitaka; Kimura, Yasuaki; Abe, Hiroshi Share Save Share Save 
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