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Andrew Tsourkas

University of Pennsylvania

58H-index
222Paper Count
1.1WCitation Count
Published Papers 109
Publication Date
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Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution-Based Biophysical Analyses
errAdvanced Materials
IF26.8
err2026-07-27
err0
errOAAI
errHannah C. Geisler; Hannah C. Safford; Ajay S. Thatte; Marshall S. Padilla; Elisa Battistini; Hannah M. Yamagata; Violet M. Ullman; Alex Chan; Benjamin E. Nachod; Anushka Agrawal; Maxwell B. Watkins; Jesse B. Hopkins; Andrew Tsourkas; Kushol Gupta; Michael J. Mitchell
errShare
errSave
Varespladib-Based Lipid Nanoparticles as Highly Efficient Anti-Inflammatory Agents for Osteoarthritis Treatment
errACS Applied Materials and Interfaces
IF8.2
err2025-10-01
err0
PREAI
errLiang, Qiushi; Gui, Tao; Luo, Lijun; Popov, Anatoliy V.; Isuri, Ritesh K.; He, Qi; Dai, Yijun; Ortved, Kyla; Tsourkas, Andrew; Qin, Ling; Cheng, Zhiliang
errShare
errSave
Using pseudo-symmetrization to overcome dendrimer surface steric crowding: a birth of L-lysine-β-alanine architecture
errRSC Adv.
IF4.6
err2025-08-20
err0
errOAAI
errYi-Meng Lo; Andrew Tsourkas; Davit Jishkariani
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errSave
Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape
errNature Nanotechnology
IF34.9
err2025-08-11
err0
PREAI
errSerena Omo-Lamai; Yufei Wang; Manthan N. Patel; Aleksa Milosavljevic; Daniel Zuschlag; Subhajit Poddar; Jichuan Wu; Liuqian Wang; Fengyi Dong; Carolann Espy; Aparajeeta Majumder; Eno-Obong Essien; Mengwen Shen; Breana Channer; Tyler E. Papp; Michael Tobin; Rhea Maheshwari; Sumin Jeong; Sofia Patel; Anit Shah; Shruthi Murali; Liam S. Chase; Marco E. Zamora; Mariah L. Arral; Oscar A. Marcos-Contreras; Jacob W. Myerson; Christopher A. Hunter; Dennis Discher; Peter J. Gaskill; Andrew Tsourkas; Vladimir R. Muzykantov; Igor Brodsky; Sunny Shin; Kathryn A. Whitehead; Hamideh Parhiz; Jeremy Katzen; Jonathan J. Miner; Dirk Trauner; Jacob S. Brenner
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errSave
Enhanced Accumulation and Penetration of Magnetic Nanoclusters in Tumors Using an 8-Magnet Halbach Array Leads to Improved Cancer Treatment
errACS NANO
IF16
err2025-01-03
err2
PREAI
errJang, B; Amirshaghaghi, A; Choi, J; Miller, J; Issadore, DA; Busch, TM; Cheng, ZL; Tsourkas, A
errShare
errSave
Integrated Imaging Probe and Bispecific Antibody Development Enables In Vivo Targeting of Glypican-3-Expressing Hepatocellular Carcinoma
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2024-09-23
err0
PREAI
errHabibollahi, Peiman; Gurevich, Alexey; Hui, James Z.; Weinfurtner, Kelly; Mcclung, George; Adler, Justin; Soulen, Michael C.; Kaplan, David E.; Nadolski, Gregory J.; Hunt, Stephen J.; Tsourkas, Andrew; Gade, Terence P.
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errSave
Lipid-mediated intracellular delivery of recombinant bioPROTACs for the rapid degradation of undruggable proteins
errNATURE COMMUNICATIONS
IF15.7
err2024-07-10
err4
errOAAI
errChan, Alexander; Haley, Rebecca M.; Najar, Mohd Altaf; Gonzalez-Martinez, David; Bugaj, Lukasz J.; Burslem, George M.; Mitchell, Michael J.; Tsourkas, Andrew
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errSave
High-Throughput Single-Cell, Single-Mitochondrial DNA Assay Using Hydrogel Droplet Microfluidics
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-03-27
err0
errOAAI
errPark, Juhwan; Kadam, Parnika S.; Atiyas, Yasemin; Chhay, Bonirath; Tsourkas, Andrew; Eberwine, James H.; Issadore, David A.
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errSave
CCR8 antibody drug conjugates: Targeting regulatory T cells for tumor sensitization
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errStafford, Lewis J.; Roth, Hayley; Campbell, Sarah; Brady, Samantha; Fiers, Valerie; Yu, FeiFan; Tsourkas, Andrew; Payne, Riley; Pitts, Meghan; Guldner, Kyle; Phillips, Tim; Tyrell, Breanna; Ulke, Colleen; Snyder, Allison; Assogba, Marianne; Ohl, Holden; Sanchez, Ileine; Doranz, Benjamin; Rucker, Joseph; Chambers, Ross
errShare
errSave
Intracellular Protein Delivery: Approaches, Challenges, and Clinical Applications
errBME FRONTIERS
IF7.7
err2024-01-25
err14
errOAAI
errChan, Alexander; Tsourkas, Andrew
errShare
errSave
Exploring the Sensitivity of Antibody-Drug Conjugate Efficacy to the Selection of Payload, Antibody, and Cell line
errBIOCONJUGATE CHEMISTRY
IF3.9
err2024-01-04
err1
PREAI
errRao, Mara; Murali, Shruthi; Amores, Danielle; Yu, Feifan; Tsourkas, Andrew
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errSave
A Novel, Micellized Naringenin Nanoparticle Rescues Hemodynamic Function PostMyocardial Infarction Via MARK4
errCIRCULATION RESEARCH
IF16.2
err2023-08-04
err0
PREAI
errWeingarten, Noah; Iyengar, Amit; Meldrum, Danika; Guevara-Plunkett, Sara; Dominic, Jessica; Amirshaghaghi, Ahmad; Nie, Daphne; Belec, Andrew; Patel, Mrinal; Ho, Joyce; Herbst, David A.; Lee, Benjamin; Eaton, Deborah; Cheng, Zhiliang; Tsourkas, Andrew; Atluri, Pavan
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errSave
Phthalocyanine-Blue Nanoparticles for the Direct Visualization of Tumors with White Light Illumination
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2023-07-03
err2
errOAAI
errAmirshaghaghi, Ahmad; Chang, Wen-Chi; Chhay, Bonirath; Bartolomeu, Ariane R.; Clapper, Margie L.; Cheng, Zhiliang; Tsourkas, Andrew
errShare
errSave
Lipid Nanoparticle Delivery of Small Proteins for Potent In Vivo RAS Inhibition
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2023-04-28
err16
PREAI
errHaley, Rebecca M.; Chan, Alexander; Billingsley, Margaret M.; Gong, Ningqiang; Padilla, Marshall S.; Kim, Emily H.; Wang, Hejia; Yin, Dingzi; Wangensteen, Kirk J.; Tsourkas, Andrew; Mitchell, Michael J.
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errSave
Activating EGFR Signaling Attenuates Osteoarthritis Development Following Loading Injury in Mice
errJOURNAL OF BONE AND MINERAL RESEARCH
IF5.9
err2022-09-30
err16
errOAAI
errGui, Tao; Wei, Yulong; Luo, Lijun; Li, Jun; Zhong, Leilei; Yao, Lutian; Beier, Frank; Nelson, Charles L.; Tsourkas, Andrew; Liu, X. Sherry; Enomoto-Iwamoto, Motomi; Yu, Feifan; Cheng, Zhiliang; Qin, Ling
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errSave
Rapid, site-specific labeling of off-the-shelf and native serum autoantibodies with T cell-redirecting domains
errSCIENCE ADVANCES
IF12.5
err2022-05-06
err1
errOAAI
errZappala, Fabiana; Higbee-Dempsey, Elizabeth; Jang, Bian; Miller, Joann; Yan, Lesan; Minutolo, Nicholas G.; Gonzalez, Gabriela T. Rosado; Tsourkas, Andrew; Ozdemir, Burcin Altun
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errSave
Superoxide dismutase-loaded porous polymersomes as highly efficient antioxidant nanoparticles targeting synovium for osteoarthritis therapy
errBIOMATERIALS
IF12.9
err2022-04-01
err50
errOAAI
errGui, Tao; Luo, Lijun; Chhay, Bonirath; Zhong, Leilei; Wei, Yulong; Yao, Lutian; Yu, Wei; Li, Jun; Nelson, Charles L.; Tsourkas, Andrew; Qin, Ling; Cheng, Zhiliang
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errSave
Rapid Production of Bispecific Antibodies from Off-the-Shelf IgGs with High Yield and Purity
errBIOCONJUGATE CHEMISTRY
IF3.9
err2021-12-12
err6
errOAAI
errMei, Linghan; Zappala, Fabiana; Tsourkas, Andrew
errShare
errSave
Biophysical Considerations in the Rational Design and Cellular Targeting of Flexible Polymeric Nanoparticles
errADVANCED MATERIALS INTERFACES
IF4.4
err2021-11-11
err3
errOAAI
errFarokhirad, Samaneh; Kandy, Sreeja Kutti; Tsourkas, Andrew; Ayyaswamy, Portonovo S.; Eckmann, David M.; Radhakrishnan, Ravi
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errSave
Efficient Labeling of Native Human IgG by Proximity-Based Sortase-Mediated Isopeptide Ligation
errBIOCONJUGATE CHEMISTRY
IF3.9
err2021-05-24
err18
errOAAI
errYu, Wendy; Gillespie, Kevin P.; Chhay, Bonirath; Svensson, Anne-Sophie; Nygren, Per-Ake; Blair, Ian A.; Yu, Feifan; Tsourkas, Andrew
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
R
Ralph Weissleder
H-index: 200 · Papers: 1.6K
B
Bert W. O’Malley
H-index: 160 · Papers: 1.4K
A
Abass Alavi
H-index: 111 · Papers: 1.9K
D
Dennis E. Discher
H-index: 106 · Papers: 569
C
Christopher A. Hunter
H-index: 102 · Papers: 511
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