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Torben Schiffner

Scripps Research Institute

25H-index
59Paper Count
2.4KCitation Count
Published Papers 28
Publication Date
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Simultaneous induction of multiple classes of broadly neutralizing antibody precursors by combination germline-targeting immunization in nonhuman primates
errScience Immunology
IF16.3
err2025-10-17
err0
PREAI
errHenry J. Sutton; Krystal M. Ma; Jon M. Steichen; Torben Schiffner; Tasha K. Altheide; Alessia Liguori; Danny Lu; Michael Kubitz; Erik Georgeson; Nicole Phelps; Ryan Tingle; Nushin B. Alavi; Elana Ben-Akiva; Xiaoya Zhou; Carolyne Kifude; Claudia T. Flynn; Eva Rakasz; Darrell J. Irvine; William R. Schief; Shane Crotty
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Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models
errScience Immunology
IF16.3
err2025-10-17
err0
PREAI
errZhenfei Xie; Xuesong Wang; Yu Yan; Jon M. Steichen; Krystal M. Ma; Christopher A. Cottrell; Eleonora Melzi; Maria Bottermann; Paula Maldonado Villavicencio; Kimmo Rantalainen; Torben Schiffner; John E. Warner; Stephanie R. Weldon; Thavaleak Prum; Jordan R. Ellis-Pugh; Jonathan L. Torres; Abigail M. Jackson; Claudia T. Flynn; Gabriel Ozorowski; Sunny Himansu; Andrea Carfi; Andrew B. Ward; Usha Nair; William R. Schief; Facundo D. Batista
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Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models
errScience Translational Medicine
IF14.6
err2025-07-30
err0
errOAAI
errParham Ramezani-Rad; Christopher A. Cottrell; Ester Marina-Zárate; Alessia Liguori; Elise Landais; Jonathan L. Torres; Amber Myers; Jeong Hyun Lee; Sabyasachi Baboo; Claudia Flynn; Katherine McKenney; Eugenia Salcedo; Xiaoya Zhou; Oleksandr Kalyuzhniy; Erik Georgeson; Nicole Phelps; Danny Lu; Saman Eskandarzadeh; Sergey Menis; Michael Kubitz; Bettina Groschel; Nushin Alavi; Abigail M. Jackson; Wen-Hsin Lee; Andy S. Tran; Elana Ben-Akiva; Katarzyna Kaczmarek Michaels; Jolene K. Diedrich; Chiamaka A. Enemuo; Vanessa Lewis; Arpan Pradhan; Sudhir Pai Kasturi; Torben Schiffner; Jon M. Steichen; Diane G. Carnathan; Sunny Himansu; John R. Yates; James C. Paulson; Gabriel Ozorowski; Darrell J. Irvine; Guido Silvestri; Devin Sok; Andrew B. Ward; Shane Crotty; William R. Schief
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Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans
errScience
IF45.8
err2025-05-15
err0
PREAI
errJordan R. Willis; Madhu Prabhakaran; Michelle Muthui; Ansuya Naidoo; Troy Sincomb; Weiwei Wu; Christopher A. Cottrell; Elise Landais; Allan C. deCamp; Nahid R. Keshavarzi; Oleksandr Kalyuzhniy; Jeong Hyun Lee; Linda M. Murungi; Wilfrida A. Ogonda; Nicole L. Yates; Martin M. Corcoran; Swastik Phulera; Joel Musando; Amanda Tsai; Gabrielle Lemire; Yiakon Sein; Michael Muteti; Praveen Alamuri; Jennifer A. Bohl; Drienna Holman; Sunny Himansu; Brett Leav; Caroline Reuter; Li-An Lin; Baoyu Ding; Chunla He; Walter L. Straus; Kellie J. MacPhee; Isabel Regadas; Diana V. Nyabundi; Ruth Chirchir; Omu Anzala; John N. Kimotho; Caleb Kibet; Kelli Greene; Hongmei Gao; Erica Beatman; Kiara Benson; Dominick Laddy; David M. Brown; Rhianna Bronson; Jalen Jean-Baptiste; Suprabhath Gajjala; Zahra Rikhtegaran-Tehrani; Alison Benner; Mukundhan Ramaswami; Danny Lu; Nushin Alavi; Sonya Amirzehni; Michael Kubitz; Ryan Tingle; Erik Georgeson; Nicole Phelps; Yumiko Adachi; Alessia Liguori; Claudia Flynn; Katherine McKenney; Xiaoya Zhou; D. Collins Owuor; Sharon A. Owuor; Soo-Young Kim; Michael Duff; Ju Yeong Kim; Grace Gibson; Sabyasachi Baboo; Jolene Diedrich; Torben Schiffner; Marisa Shields; Mabela Matsoso; Jennifer Santos; Kristen Syvertsen; Allison Kennedy; Melissa Schroeter; Johan Vekemans; John R. Yates; James C. Paulson; Ollivier Hyrien; Adrian B. McDermott; Pholo Maenetje; Julien Nyombayire; Etienne Karita; Rosine Ingabire; Vinodh Edward; Vincent Muturi-Kioi; Janine Maenza; Adrienne E. Shapiro; M. Juliana McElrath; Srilatha Edupuganti; Barbara S. Taylor; David Diemert; Gabriel Ozorowski; Richard A. Koup; David Montefiori; Andrew B. Ward; Gunilla B. Karlsson Hedestam; Georgia Tomaras; Devin J. Hunt; Daniel Muema; Devin Sok; Dagna S. Laufer; Sarah F. Andrews; Eunice W. Nduati; William R. Schief
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Vaccination induces broadly neutralizing antibody precursors to HIV gp41 (vol 25, pg 1073, 2024)
errNATURE IMMUNOLOGY
IF27.6
err2024-06-14
err0
errOAAI
errSchiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; McKenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schultze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R.
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Vaccination induces broadly neutralizing antibody precursors to HIV gp41
errNATURE IMMUNOLOGY
IF27.6
err2024-05-30
err9
errOAAI
errSchiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; Mckenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schulze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates III, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R.
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Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-05-22
err3
errOAAI
errCottrell, Christopher A.; Hu, Xiaozhen; Lee, Jeong Hyun; Skog, Patrick; Luo, Sai; Flynn, Claudia T.; McKenney, Katherine R.; Hurtado, Jonathan; Kalyuzhniy, Oleksandr; Liguori, Alessia; Willis, Jordan R.; Landais, Elise; Raemisch, Sebastian; Chen, Xuejun; Baboo, Sabyasachi; Himansu, Sunny; Diedrich, Jolene K.; Duan, Hongying; Cheng, Cheng; Schiffner, Torben; Bader, Daniel L. V.; Kulp, Daniel W.; Tingle, Ryan; Georgeson, Erik; Eskandarzadeh, Saman; Alavi, Nushin; Lu, Danny; Sincomb, Troy; Kubitz, Michael; Mullen, Tina-Marie; Yates, John R., III; Paulson, James C.; Mascola, John R.; Alt, Frederick W.; Briney, Bryan; Sok, Devin; Schief, William R.
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Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens
errNPJ VACCINES
IF6.5
err2023-07-13
err3
errOAAI
errMartin, Gregory M.; Russell, Rebecca A.; Mundsperger, Philip; Harris, Scarlett; Jovanoska, Lu; Trajano, Luiza Farache; Schiffner, Torben; Fabian, Katalin; Tolazzi, Monica; Scarlatti, Gabriella; McFarlane, Leon; Cheeseman, Hannah; Aldon, Yoann; Schermer, Edith E.; Breemen, Marielle; Sliepen, Kwinten; Katinger, Dietmar; Kunert, Renate; Sanders, Rogier W.; Shattock, Robin; Ward, Andrew B.; Sattentau, Quentin J.
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Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
errIMMUNITY
IF26.3
err2022-11-01
err21
errOAAI
errWillis, Jordan R.; Berndsen, Zachary T.; Ma, Krystal M.; Steichen, Jon M.; Schiffner, Torben; Landais, Elise; Liguori, Alessia; Kalyuzhniy, Oleksandr; Allen, Joel D.; Baboo, Sabyasachi; Omorodion, Oluwarotimi; Diedrich, Jolene K.; Hu, Xiaozhen; Georgeson, Erik; Phelps, Nicole; Eskandarzadeh, Saman; Groschel, Bettina; Kubitz, Michael; Adachi, Yumiko; Mullin, Tina-Marie; Alavi, Nushin B.; Falcone, Samantha; Himansu, Sunny; Carfi, Andrea; Wilson, Ian A.; Yates, John R.; Paulson, James C.; Crispin, Max; Ward, Andrew B.; Schief, William R.
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Immunogenicity of a germline-targeting nanoparticle in knock-in mice expressing human B cell receptors of the HIV gp41 neutralizing antibody, DH511
errJOURNAL OF IMMUNOLOGY
IF3.4
err2022-05-01
err0
PREAI
errCain, Derek Wilson; Tian, Ming; Schiffner, Torben; Rantalainen, Kimmo; Saunders, Kevin O.; Wiehe, Kevin; Watts, Brian; Ward, Andrew; Ofek, Gilad; Alt, Frederick W.; Haynes, Barton F.; Schief, William R.; Alam, S. Munir
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DeGlyPHER: An Ultrasensitive Method for the Analysis of Viral Spike N-Glycoforms
errANALYTICAL CHEMISTRY
IF6.7
err2021-10-01
err13
errOAAI
errBaboo, Sabyasachi; Diedrich, Jolene K.; Martinez-Bartolome, Salvador; Wang, Xiaoning; Schiffner, Torben; Groschel, Bettina; Schief, William R.; Paulson, James C.; Yates, John R., III
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Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates
errBIOMATERIALS
IF12.9
err2021-08-01
err22
errOAAI
errMartin, Jacob T.; Hartwell, Brittany L.; Kumarapperuma, Sidath C.; Melo, Mariane B.; Carnathan, Diane G.; Cossette, Benjamin J.; Adams, Josetta; Gong, Siqi; Zhang, Wei; Tokatlian, Talar; Menis, Sergey; Schiffner, Torben; Franklin, Crystal G.; Goins, Beth; Fox, Peter T.; Silvestri, Guido; Schief, William R.; Ruprecht, Ruth M.; Irvine, Darrell J.
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Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells (vol 11, 5850, 2020)
errNATURE COMMUNICATIONS
IF15.7
err2020-12-07
err0
errOAAI
errHuang, Deli; Tran, Jenny Tuyet; Olson, Alex; Vollbrecht, Thomas; Tenuta, Mary; Guryleva, Mariia V.; Fuller, Roberta P.; Schiffner, Torben; Abadejos, Justin R.; Couvrette, Lauren; Blane, Tanya R.; Saye, Karen; Li, Wenjuan; Landais, Elise; Gonzalez-Martin, Alicia; Schief, William; Murrell, Ben; Burton, Dennis R.; Nemazee, David; Voss, James E.
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Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells
errNATURE COMMUNICATIONS
IF15.7
err2020-11-17
err54
errOAAI
errHuang, Deli; Tran, Jenny Tuyet; Olson, Alex; Vollbrecht, Thomas; Tenuta, Mary; Guryleva, Mariia, V; Fuller, Roberta P.; Schiffner, Torben; Abadejos, Justin R.; Couvrette, Lauren; Blane, Tanya R.; Saye, Karen; Li, Wenjuan; Landais, Elise; Gonzalez-Martin, Alicia; Schief, William; Murrell, Ben; Burton, Dennis R.; Nemazee, David; Voss, James E.
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B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-09-01
err43
errOAAI
errHuang, Deli; Abbott, Robert K.; Havenar-Daughton, Colin; Skog, Patrick D.; Al-Kolla, Rita; Groschel, Bettina; Blane, Tanya R.; Menis, Sergey; Tran, Jenny Tuyet; Thinnes, Theresa C.; Volpi, Sabrina A.; Liguori, Alessia; Schiffner, Torben; Villegas, Sophia M.; Kalyuzhniy, Oleksandr; Pintea, Mark; Voss, James E.; Phelps, Nicole; Tingle, Ryan; Rodriguez, Alberto R.; Martin, Greg; Kupryianov, Sergey; deCamp, Allan; Schief, William R.; Nemazee, David; Crotty, Shane
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errSave
Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations
errNPJ VACCINES
IF6.5
err2020-08-05
err43
errOAAI
errMartin, Jacob T.; Cottrell, Christopher A.; Antanasijevic, Aleksandar; Carnathan, Diane G.; Cossette, Benjamin J.; Enemuo, Chiamaka A.; Gebru, Etse H.; Choe, Yury; Viviano, Federico; Fischinger, Stephanie; Tokatlian, Talar; Cirelli, Kimberly M.; Ueda, George; Copps, Jeffrey; Schiffner, Torben; Menis, Sergey; Alter, Galit; Schief, William R.; Crotty, Shane; King, Neil P.; Baker, David; Silvestri, Guido; Ward, Andrew B.; Irvine, Darrell J.
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HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies
errCELL REPORTS
IF6.9
err2020-04-01
err61
errOAAI
errRantalainen, Kimmo; Berndsen, Zachary T.; Antanasijevic, Aleksandar; Schiffner, Torben; Zhang, Xi; Lee, Wen-Hsin; Torres, Jonathan L.; Zhang, Lei; Irimia, Adriana; Copps, Jeffrey; Zhou, Kenneth H.; Kwon, Young D.; Law, William H.; Schramm, Chaim A.; Verardi, Raffaello; Krebs, Shelly J.; Kwong, Peter D.; Doria-Rose, Nicole A.; Wilson, Ian A.; Zwick, Michael B.; Yates, John R., III; Schief, William R.; Ward, Andrew B.
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Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan
errIMMUNITY
IF26.3
err2019-07-01
err70
errOAAI
errUmotoy, Jeffrey; Bagaya, Bernard S.; Joyce, Collin; Schiffner, Torben; Menis, Sergey; Saye-Francisco, Karen L.; Biddle, Trevor; Mohan, Sanjay; Vollbrecht, Thomas; Kalyuzhniy, Oleksander; Madzorera, Sharon; Kitchin, Dale; Lambson, Bronwen; Nonyane, Molati; Kilembe, William; Poignard, Pascal; Schief, William R.; Burton, Dennis R.; Murrell, Ben; Moore, Penny L.; Briney, Bryan; Sok, Devin; Landais, Elise
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errSave
The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2018-07-04
err119
errOAAI
errHavenar-Daughton, Colin; Sarkar, Anita; Kulp, Daniel W.; Toy, Laura; Hu, Xiaozhen; Deresa, Isaiah; Kalyuzhniy, Oleksandr; Kaushik, Kirti; Upadhyay, Amit A.; Menis, Sergey; Landais, Elise; Cao, Liwei; Diedrich, Jolene K.; Kumar, Sonu; Schiffner, Torben; Reiss, Samantha M.; Seumois, Gregory; Yates, John R.; Paulson, James C.; Bosinger, Steven E.; Wilson, Ian A.; Schief, William R.; Crotty, Shane
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Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins
errPLOS PATHOGENS
IF4.9
err2018-05-10
err22
errOAAI
errSchiffner, Torben; Pallesen, Jesper; Russell, Rebecca A.; Dodd, Jonathan; de Val, Natalia; LaBranche, Celia C.; Montefiori, David; Tomaras, Georgia D.; Shen, Xiaoying; Harris, Scarlett L.; Moghaddam, Amin E.; Kalyuzhniy, Oleksandr; Sanders, Rogier W.; McCoy, Laura E.; Moore, John P.; Ward, Andrew B.; Sattentau, Quentin J.
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Research Directions

No research directions
Co-authors
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