Not logged inTissue Organoid Cultures Metabolize Dietary Carcinogens Proficiently and Are Effective Models for DNA Adduct Formation
Garcia, Angela L. Caipa; Kucab, Jill E.; Al-Serori, Halh; Beck, Rebekah S. S.; Bellamri, Madjda; Turesky, Robert J.; Groopman, John D.; Francies, Hayley E.; Garnett, Mathew J.; Huch, Meritxell; Drost, Jarno; Zilbauer, Matthias; Arlt, Volker M.; Phillips, David H.
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SaveMutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo [4,5-b] pyridine (N-OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts
Holzl-Armstrong, Lisa; Moody, Sarah; Kucab, Jill E.; Zwart, Edwin P.; Bellamri, Medjda; Luijten, Mirjam; Turesky, Robert J.; Stratton, Michael R.; Arlt, Volker M.; Phillips, David H.
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SaveMutagenicity of acrylamide and glycidamide in humanTP53knock-in (Hupki) mouse embryo fibroblasts
Holzl-Armstrong, Lisa; Kucab, Jill E.; Moody, Sarah; Zwart, Edwin P.; Loutkotova, Lucie; Duffy, Veronica; Luijten, Mirjam; da Costa, Goncalo Gamboa; Stratton, Michael R.; Phillips, David H.; Arlt, Volker M.
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SavePreferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival
Troussard, AA; McDonald, PC; Wederell, ED; Mawji, NM; Filipenko, NR; Gelmon, KA; Kucab, JE; Dunn, SE; Emerman, JT; Bally, MB; Dedhar, S
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SaveCelecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours
Kucab, JE; Lee, C; Chen, CS; Zhu, JX; Gilks, CB; Cheang, M; Huntsman, D; Yorida, E; Emerman, J; Pollak, M; Dunn, SE
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SaveAkt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells
Sutherland, BW; Kucab, J; Wu, J; Lee, C; Cheang, MCU; Yorida, E; Turbin, D; Dedhar, S; Nelson, C; Pollak, M; Grimes, HL; Miller, K; Badve, S; Huntsman, D; Blake-Gilks, C; Chen, M; Pallen, CJ; Dunn, SE
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SaveExpression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast cancer is associated with poor survival: Potential for intervention with 17-allylamino geldanamycin
Nielsen, TO; Andrews, HN; Cheang, M; Kucab, JE; Hsu, FD; Ragaz, J; Gilks, CB; Makretsov, N; Bajdik, CD; Brookes, C; Neckers, LM; Evdokimova, V; Huntsman, DG; Dunn, SE
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SaveInsulin-like growth factor-1 inscribes a gene expression profile for angiogenic factors and cancer progression in breast epithelial cells
Oh, JS; Kucab, JE; Bushel, PR; Martin, K; Bennett, L; Collins, J; DiAugustine, RP; Barrett, JC; Afshari, CA; Dunn, SE
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