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Uncialamycin-based antibody-drug conjugates: Unique enediyne ADCs exhibiting bystander killing effect Nicolaou, K. C.; Rigol, Stephan; Pitsinos, Emmanuel N.; Das, Dipendu; Lu, Yong; Rout, Subhrajit; Schammel, Alexander W.; Holte, Dane; Lin, Baiwei; Gu, Christine; Sarvaiya, Hetal; Trinidad, Jose; Barbour, Nicole; Valdiosera, Amanda M.; Sandoval, Joseph; Lee, Christina; Aujay, Monette; Fernando, Hanan; Dhar, Anukriti; Karsunky, Holger; Taylor, Nicole; Pysz, Marybeth; Gavrilyuk, Julia Share Save
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Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis Nicolaou, K. C.; Pan, Saiyong; Pulukuri, Kiran K.; Ye, Qiuji; Rigol, Stephan; Erande, Rohan D.; Vourloumis, Dionisios; Nocek, Boguslaw P.; Munneke, Stefan; Lyssikatos, Joseph; Valdiosera, Amanda; Gu, Christine; Lin, Baiwei; Sarvaiaya, Hetal; Trinidad, Jose; Sandoval, Joseph; Lee, Christina; Hammond, Mikhail; Aujay, Monette; Taylor, Nicole; Pysz, Marybeth; Purcell, James W.; Gavrilyuk, Julia Share Save
Design, Synthesis, and Biological Investigation of Thailanstatin A and Spliceostatin D Analogues Containing Tetrahydropyran, Tetrahydrooxazine, and Fluorinated Structural Motifs Nicolaou, K. C.; Rekula, Santhosh Reddy; Kumar, S. Mothish; Podilapu, Ananda Rao; Matuszak, Ryan P.; Jung, Paul M.; Lam, Lloyd T.; Phillips, Andrew C.; Lyssikatos, Joseph; Munneke, Stefan; Gu, Christine; Sarvaiya, Hetal; Sandoval, Joseph; Hammond, Mikhail; Aujay, Monette; Purcell, James W.; Reilly, Regina M.; Gavrilyuk, Julia Share Save
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Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues Nicolaou, K. C.; Krieger, Johannes; Murhade, Ganesh M.; Subramanian, Parthasarathi; Dherange, Balu D.; Vourloumis, Dionisios; Munneke, Stefan; Lin, Baiwei; Gu, Christine; Sarvaiaya, Hetal; Sandoval, Joseph; Zhang, Zhaomei; Aujay, Monette; Purcell, James W.; Gavrilyuk, Julia Share Save
Synthesis and Biological Evaluation of Shishijimicin A-Type Linker-Drugs and Antibody-Drug Conjugates Nicolaou, K. C.; Li, Ruofan; Chen, Qifeng; Lu, Zhaoyong; Pitsinos, Emmanuel N.; Schammel, Alexander; Lin, Baiwei; Gu, Christine; Sarvaiya, Hetal; Tchelepi, Robert; Valdiosera, Amanda; Clubb, Justin; Barbour, Nicole; Sisodiya, Vikram; Sandoval, Joseph; Lee, Christina; Aujay, Monette; Gavrilyuk, Julia Share Save
Design, Synthesis, and Biological Investigation of Epothilone B Analogues Featuring Lactone, Lactam, and Carbocyclic Macrocycles, Epoxide, Aziridine, and 1,1-Difluorocyclopropane and Other Fluorine Residues Nicolaou, K. C.; Shelke, Yogesh G.; Dherange, Balu D.; Kempema, Aaron; Lin, Baiwei; Gu, Christine; Sandoval, Joseph; Hammond, Mikhail; Aujay, Monette; Gavrilyuk, Julia Share Save
Total Synthesis and Biological Evaluation of Tiancimycins A and B, Yangpumicin A, and Related Anthraquinone-Fused Enediyne Antitumor Antibiotics Nicolaou, K. C.; Das, Dipendu; Lu, Yong; Rout, Subhrajit; Pitsinos, Emmanuel N.; Lyssikatos, Joseph; Schammel, Alexander; Sandoval, Joseph; Hammond, Mikhail; Aujay, Monette; Gavrilyuk, Julia Share Save
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Short Total Synthesis of Δ12-Prostaglandin J2 and Related Prostaglandins. Design, Synthesis, and Biological Evaluation of Macrocyclic Δ12-Prostaglandin J2 Analogues (vol 84, pg 365, 2019) Nicolaou, K. C.; Pulukuri, Kiran Kumar; Rigol, Stephan; Peitsinis, Zisis; Yu, Ruocheng; Kishigami, Satoshi; Cen, Nicholas; Aujay, Monette; Sandoval, Joseph; Zepeda, Nancy; Gavrilyuk, Julia Share Save
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Short Total Synthesis of Δ12-Prostaglandin J2 and Related Prostaglandins. Design, Synthesis, and Biological Evaluation of Macrocyclic Δ12-Prostaglandin J2 Analogues Nicolaou, K. C.; Pulukuri, Kiran Kumar; Rigol, Stephan; Peitsinis, Zisis; Yu, Ruocheng; Kishigami, Satoshi; Cen, Nicholas; Aujay, Monette; Sandoval, Joseph; Zepeda, Nancy; Gavrilyuk, Julia Share Save
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