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Transkingdom Network Analysis (TkNA): a systems framework for inferring causal factors underlying host-microbiota and other multi-omic interactions Newman, Nolan K.; Macovsky, Matthew S.; Rodrigues, Richard R.; Bruce, Amanda M.; Pederson, Jacob W.; Padiadpu, Jyothi; Shan, Jigui; Williams, Joshua; Patil, Sankalp S.; Dzutsev, Amiran K.; Shulzhenko, Natalia; Trinchieri, Giorgio; Brown, Kevin; Morgun, Andrey Share Save
Intestinal IL-22RA1 signaling regulates intrinsic and systemic lipid and glucose metabolism to alleviate obesity-associated disorders Gaudino, Stephen J.; Singh, Ankita; Huang, Huakang; Padiadpu, Jyothi; Jean-Pierre, Makheni; Kempen, Cody; Bahadur, Tej; Shiomitsu, Kiyoshi; Blumberg, Richard; Shroyer, Kenneth R.; Beyaz, Semir; Shulzhenko, Natalia; Morgun, Andrey; Kumar, Pawan Share Save
Multi-omic network analysis identified betacellulin as a novel target of omega-3 fatty acid attenuation of western diet-induced nonalcoholic steatohepatitis Padiadpu, Jyothi; Garcia-Jaramillo, Manuel; Newman, Nolan K.; Pederson, Jacob W.; Rodrigues, Richard; Li, Zhipeng; Singh, Sehajvir; Monnier, Philip; Trinchieri, Giorgio; Brown, Kevin; Dzutsev, Amiran K.; Shulzhenko, Natalia; Jump, Donald B.; Morgun, Andrey Share Save
Reducing gut microbiome-driven adipose tissue inflammation alleviates metabolic syndrome Newman, N. K.; Zhang, Y.; Padiadpu, J.; Miranda, C. L.; Magana, A. A.; Wong, C. P.; Hioki, K. A.; Pederson, J. W.; Li, Z.; Gurung, M.; Bruce, A. M.; Brown, K.; Bobe, G.; Sharpton, T. J.; Shulzhenko, N.; Maier, C. S.; Stevens, J. F.; Gombart, A. F.; Morgun, A. Share Save
Early transcriptome changes associated with western diet induced NASH in Ldlr-/- mice points to activation of hepatic macrophages and an acute phase response Padiadpu, Jyothi; Spooner, Melinda H.; Li, Zhipeng; Newman, Nolan; Lohr, Christiane V.; Apperson, K. Denise; Dzutsev, Amiran; Trinchieri, Giorgio; Shulzhenko, Natalia; Morgun, Andrey; Jump, Donald B. Share Save
GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology Earley, Zachary M.; Lisicka, Wioletta; Sifakis, Joseph J.; Aguirre-Gamboa, Raul; Kowalczyk, Anita; Barlow, Jacob T.; Shaw, Dustin G.; Discepolo, Valentina; Tan, Ineke L.; Gona, Saideep; Ernest, Jordan D.; Matzinger, Polly; Barreiro, Luis B.; Morgun, Andrey; Bendelac, Albert; Ismagilov, Rustem F.; Shulzhenko, Natalia; Riesenfeld, Samantha J.; Jabri, Bana Share Save
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Microbiota and adipocyte mitochondrial damage in type 2 diabetes are linked by Mmp12+ macrophages Li, Zhipeng; Gurung, Manoj; Rodrigues, Richard R.; Padiadpu, Jyothi; Newman, Nolan K.; Manes, Nathan P.; Pederson, Jacob W.; Greer, Renee L.; Vasquez-Perez, Stephany; You, Hyekyoung; Hioki, Kaito A.; Moulton, Zoe; Fel, Anna; De Nardo, Dominic; Dzutsev, Amiran K.; Nita-Lazar, Aleksandra; Trinchieri, Giorgio; Shulzhenko, Natalia; Morgun, Andrey Share Save
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Dietary Indole-3-Carbinol Activates AhR in the Gut, Alters Th17-Microbe Interactions, and Exacerbates Insulitis in NOD Mice Kahalehili, Heather M.; Newman, Nolan K.; Pennington, Jamie M.; Kolluri, Siva K.; Kerkvliet, Nancy, I; Shulzhenko, Natalia; Morgun, Andrey; Ehrlich, Allison K. Share Save
Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes Rodrigues, Richard R.; Gurung, Manoj; Li, Zhipeng; Garcia-Jaramillo, Manuel; Greer, Renee; Gaulke, Christopher; Bauchinger, Franziska; You, Hyekyoung; Pederson, Jacob W.; Vasquez-Perez, Stephany; White, Kimberly D.; Frink, Briana; Philmus, Benjamin; Jump, Donald B.; Trinchieri, Giorgio; Berry, David; Sharpton, Thomas J.; Dzutsev, Amiran; Morgun, Andrey; Shulzhenko, Natalia Share Save
Germ-Free Swiss Webster Mice on a High-Fat Diet Develop Obesity, Hyperglycemia, and Dyslipidemia Logan, Isabelle E.; Bobe, Gerd; Miranda, Cristobal L.; Vasquez-Perez, Stephany; Choi, Jaewoo; Lowry, Malcolm B.; Sharpton, Thomas J.; Morgun, Andrey; Maier, Claudia S.; Stevens, Jan E.; Shulzhenko, Natalia; Gombart, Adrian E. Share Save
Gut-resident CX3CR1hi macrophages induce tertiary lymphoid structures and IgA response in situ Koscso, Balazs; Kurapati, Sravya; Rodrigues, Richard R.; Nedjic, Jelena; Gowda, Kavitha; Shin, Changsik; Soni, Chetna; Ashraf, Azree Zaffran; Purushothaman, Indira; Palisoc, Maryknoll; Xu, Sulei; Sun, Haoyu; Chodisetti, Sathi Babu; Lin, Eugene; Mack, Matthias; Kawasawa, Yuka Imamura; He, Pingnian; Rahman, Ziaur S. M.; Aifantis, Iannis; Shulzhenko, Natalia; Morgun, Andrey; Bogunovic, Milena Share Save
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Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells Bodogai, Monica; O'Connell, Jennifer; Kim, Ki; Kim, Yoo; Moritoh, Kanako; Chen, Chen; Gusev, Fedor; Vaughan, Kelli; Shulzhenko, Natalia; Mattison, Julie A.; Lee-Chang, Catalina; Chen, Weixuan; Carlson, Olga; Becker, Kevin G.; Gurung, Manoj; Morgun, Andrey; White, James; Meade, Theresa; Perdue, Kathy; Mack, Matthias; Ferrucci, Luigi; Trinchieri, Giorgio; de Cabo, Rafael; Rogaev, Evgeny; Egan, Josephine; Wu, Jiejun; Biragyn, Arya Share Save
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