Not logged in Single- cell analysis of treatment- resistant prostate cancer: Implications of cell state changes for cell surface antigen- targeted therapies Zaidi, Samir; Park, Jooyoung; Chan, Joseph M.; Roudier, Martine P.; Zhao, Jimmy L.; Gopalan, Anuradha; Wadosky, Kristine M.; Patel, Radhika A.; Sayar, Erolcan; Karthaus, Wouter R.; Kates, D. Henry; Chaudhary, Ojasvi; Xu, Tianhao; Masilionis, Ignas; Mazutis, Linas; Chaligne, Ronan; Obradovic, Aleksandar; Linkov, Irina; Barlas, Afsar; Jungbluth, Achim A.; Rekhtman, Natasha; Silber, Joachim; Manova-Todorova, Katia; Watson, Philip A.; True, Lawrence D.; Morrissey, Colm; Scher, Howard I.; Rathkopf, Dana E.; Morris, Michael J.; Goodrich, David W.; Choi, Jungmin; Nelson, Peter S.; Haffner, Michael C.; Sawyers, Charles L. Share Save
Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates Ajkunic, Azra; Sayar, Erolcan; Roudier, Martine P.; Patel, Radhika A.; Coleman, Ilsa M.; De Sarkar, Navonil; Hanratty, Brian; Adil, Mohamed; Zhao, Jimmy; Zaidi, Samir; True, Lawrence D.; Sperger, Jamie M.; Cheng, Heather H.; Yu, Evan Y.; Montgomery, Robert B.; Hawley, Jessica E.; Ha, Gavin; Persse, Thomas; Galipeau, Patricia; Lee, John K.; Harmon, Stephanie A.; Corey, Eva; Lang, Joshua M.; Sawyers, Charles L.; Morrissey, Colm; Schweizer, Michael T.; Gulati, Roman; Nelson, Peter S.; Haffner, Michael C. Share Save
LIN28B/HMGA2 axis accelerates PDA by promoting oncogenic protein synthesis Dobersch, Stephanie; Cavendar, Sarah; Yamamoto, Naomi; Boila, Liberales Debraj; Wladyka, Cindy; Roudier, Martine; Notta, Faiyaz; Eisenman, Robert; Hsieh, Andrew; Kugel, Sita Share Save
Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models Agarwal, Supreet; Fang, Lei; Mcgowen, Kerry; Yin, Juanjuan; Bowman, Joel; Ku, Anson T.; Alilin, Aian Neil; Corey, Eva; Roudier, Martine P.; True, Lawrence D.; Dumpit, Ruth; Coleman, Ilsa; Lee, John K.; Nelson, Peter S.; Capaldo, Brian J.; Mariani, Aida; Hoover, Clare; Senatorov, Ilya S.; Beshiri, Michael; Sowalsky, Adam G.; Hurt, Elaine M.; Kelly, Kathleen Share Save
Characterization of HOXB13 expression patterns in localized and metastatic castration-resistant prostate cancer Patel, Radhika A.; Sayar, Erolcan; Coleman, Ilsa; Roudier, Martine P.; Hanratty, Brian; Low, Jin-Yih; Jaiswal, Neha; Ajkunic, Azra; Dumpit, Ruth; Ercan, Caner; Salama, Nina; O'Brien, Valerie P.; Isaacs, William B.; Epstein, Jonathan, I; De Marzo, Angelo M.; Trock, Bruce J.; Luo, Jun; Brennen, W. Nathaniel; Tretiakova, Maria; Vakar-Lopez, Funda; True, Lawrence D.; Goodrich, David W.; Corey, Eva; Morrissey, Colm; Nelson, Peter S.; Hurley, Paula J.; Gulati, Roman; Haffner, Michael C. Share Save
Androgen-regulated stromal complement component 7 (C7) suppresses prostate cancer growth Zhou, Zhicheng; Jia, Deyong; Kwon, Ohjoon; Li, Shan; Sun, Huiyun; Roudier, Martine P.; Lin, Daniel W. W.; True, Lawrence; Morrissey, Colm; Creighton, Chad J.; Lee, John K. K.; Xin, Li Share Save
Molecular phenotype classification of metastatic prostate cancer by cell-free DNA methylation analysis Adil, Mohamed; Hanratty, Brian; Mustafi, Pallabi; Coleman, Ilsa; Patel, Radhika; Doebley, Anna-Lisa; Patton, Robert; Cruikshank, Eden; Galipeau, Patricia; Dumpit, Ruth; Roudier, Martine; Low, Jin-Yih; De Sarkar, Navonil; Montgomery, Robert; Corey, Eva; Morrissey, Colm; Nelson, Peter; Ha, Gavin; Haffner, Michael Share Save
Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy Bhatia, Vipul; Kamat, Nikhil V.; Pariva, Tiffany E.; Wu, Li-Ting; Tsao, Annabelle; Sasaki, Koichi; Sun, Huiyun; Javier, Gerardo; Nutt, Sam; Coleman, Ilsa; Hitchcock, Lauren; Zhang, Ailin; Rudoy, Dmytro; Gulati, Roman; Patel, Radhika A.; Roudier, Martine P.; True, Lawrence D.; Srivastava, Shivani; Morrissey, Colm M.; Haffner, Michael C.; Nelson, Peter S.; Priceman, Saul J.; Ishihara, Jun; Lee, John K. Share Save
Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer Sayar, Erolcan; Patel, Radhika A.; Coleman, Ilsa M.; Roudier, Martine P.; Zhang, Ailin; Mustafi, Pallabi; Low, Jin-Yih; Hanratty, Brian; Ang, Lisa S.; Bhatia, Vipul; Adil, Mohamed; Bakbak, Hasim; Quigley, David A.; Schweizer, Michael T.; Hawley, Jessica E.; Kollath, Lori; True, Lawrence D.; Feng, Felix Y.; Bander, Neil H.; Corey, Eva; Lee, John K.; Morrissey, Colm; Gulati, Roman; Nelson, Peter S.; Haffner, Michael C. Share Save
Stromal FOXF2 suppresses prostate cancer progression and metastasis by enhancing antitumor immunity Jia, Deyong; Zhou, Zhicheng; Kwon, Oh-Joon; Zhang, Li; Wei, Xing; Zhang, Yiqun; Yi, Mingyang; Roudier, Martine P.; Regier, Mary C.; Dumpit, Ruth; Nelson, Peter S.; Headley, Mark; True, Lawrence; Lin, Daniel W.; Morrissey, Colm; Creighton, Chad J.; Xin, Li Share Save
Retrospective analysis of Schlafen11 (SLFN11) to predict the outcomes to therapies affecting the DNA damage response Willis, Sophie E.; Winkler, Claudia; Roudier, Martine P.; Baird, Tarrion; Marco-Casanova, Paola; Jones, Emma, V; Rowe, Philip; Rodriguez-Canales, Jaime; Angell, Helen K.; Ng, Felicia S. L.; Waring, Paul M.; Hodgson, Darren; Ledermann, Jonathan A.; Weberpals, Johanne, I; Dean, Emma; Harrington, Elizabeth A.; Barrett, J. Carl; Pierce, Andrew J.; Leo, Elisabetta; Jones, Gemma N. Share Save
Regulation of telomere homeostasis and genomic stability in cancer by N6-adenosine methylation (m6A) Lee, Ji Hoon; Hong, Juyeong; Zhang, Zhao; Avalos, Barbara de la Pena; Proietti, Cecilia J.; Deamicis, Agustina Roldan; Guzman, Pablo G.; Lam, Hung-Ming; Garcia, Jose; Roudier, Martine P.; Sisk, Anthony E.; De la Rosa, Richard; Vu, Kevin; Yang, Mei; Liao, Yiji; Scheirer, Jessica; Pechacek, Douglas; Yadav, Pooja; Rao, Manjeet K.; Zheng, Siyuan; Johnson-Pais, Teresa L.; Leach, Robin J.; Elizalde, Patricia, V; Dray, Eloise; Xu, Kexin Share Save
Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling Brady, Lauren; Kriner, Michelle; Coleman, Ilsa; Morrissey, Colm; Roudier, Martine; True, Lawrence D.; Gulati, Roman; Plymate, Stephen R.; Zhou, Zoey; Birditt, Brian; Meredith, Rhonda; Geiss, Gary; Hoang, Margaret; Beechem, Joseph; Nelson, Peter S. Share Save
AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib Flemington, Vikki; Davies, Emma J.; Robinson, David; Sandin, Linda C.; Delpuech, Oona; Zhang, Pei; Hanson, Lyndsey; Farrington, Paul; Bell, Sigourney; Falenta, Katarzyna; Gibbons, Francis D.; Lindsay, Nicola; Smith, Aaron; Wilson, Joanne; Roberts, Karen; Tonge, Michael; Hopcroft, Philip; Willis, Sophie E.; Roudier, Martine P.; Rooney, Claire; Coker, Elizabeth A.; Jaaks, Patricia; Garnett, Mathew J.; Fawell, Stephen E.; Jones, Clifford D.; Ward, Richard A.; Simpson, Iain; Cosulich, Sabina C.; Pease, J. Elizabeth; Smith, Paul D. Share Save
Genomic and phenotypic heterogeneity in prostate cancer Haffner, Michael C.; Zwart, Wilbert; Roudier, Martine P.; True, Lawrence D.; Nelson, William G.; Epstein, Jonathan, I; De Marzo, Angelo M.; Nelson, Peter S.; Yegnasubramanian, Srinivasan Share Save
A Phase 1 study of gefitinib combined with durvalumab in EGFR TKI-naive patients withEGFRmutation-positive locally advanced/metastatic non-small-cell lung cancer Creelan, Benjamin C.; Yeh, Tammie C.; Kim, Sang-We; Nogami, Naoyuki; Kim, Dong-Wan; Chow, Laura Q. M.; Kanda, Shintaro; Taylor, Rosemary; Tang, Weifeng; Tang, Mei; Angell, Helen K.; Roudier, Martine P.; Marotti, Marcelo; Gibbons, Don L. Share Save
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Capivasertib (AZD5363) in combination with fulvestrant in PTEN-mutant ER plus metastatic breast cancer Smyth, Lillian M.; Batist, Gerald; Meric-Bernstam, Funda; Kabos, Peter; Spanggaard, Iben; Lluch, Ana; Schram, Alison; Varga, Andrea; Wong, Andrea; Ambrose, Helen; Barnicle, Alan; Carr, T. Hedley; de Bruin, Elza C.; Salinas-Souza, Carolina; Foxley, Andrew; Hauser, Joana; Lindemann, Justin P. O.; Maudsley, Rhiannon; McEwen, Robert; Moschetta, Michele; Roudier, Martine; Schiavon, Gaia; Razavi, Pedram; Banerji, Udai; Chandarlapaty, Sarat; Baselga, Jose; Hyman, David M. Share Save
A pre-surgical, window of opportunity study comparing the novel oral SERD AZD9496 with fulvestrant in patients with newly diagnosed ER+HER2-primary breast cancer Robertson, John F. R.; Evans, Abigail; Henschen, Stephan; Kirwan, Cliona; Jahan, Ali; Kenny, Laura; Dixon, J. Michael; Schmid, Peter; Kothari, Ashutosh; Mohamed, Omar; Fasching, Peter A.; Cheung, Kwok-Leung; Wuerstlein, Rachel; Carroll, Danielle; Klinowska, Teresa; Lindemann, Justin P. O.; MacDonald, Alexander; Mather, Richard; Maudsley, Rhiannon; Moschetta, Michele; Nikolaou, Myria; Roudier, Martine P.; Sarvotham, Tinnu; Schiavon, Gaia; Zhou, Diansong; Zhou, Li; Harbeck, Nadia Share Save
A phase II study to assess the safety and efficacy of the dual mTORC1/2 inhibitor vistusertib in relapsed, refractory DLBCL Eyre, Toby A.; Hildyard, Catherine; Hamblin, Angela; Ali, Ayesha S.; Houlton, Aimee; Hopkins, Louise; Royston, Daniel; Linton, Kim M.; Pettitt, Andrew; Rule, Simon; Cwynarski, Kate; Barrington, Sally F.; Warbey, Victoria; Wrench, David; Barrans, Sharon; Hirst, Caroline S.; Panchal, Anesh; Roudier, Martine P.; Harrington, Elizabeth A.; Davies, Andrew; Collins, Graham P. Share Save
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