Not logged in Share Save
Share Save
Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations (vol 4, pg 1345, 2023) Miyazaki, Isao; Odintsov, Igor; Ishida, Keiji; Lui, Allan J. W.; Kato, Masanori; Suzuki, Tatsuya; Zhang, Tom; Wakayama, Kentaro; Kurth, Renate I.; Cheng, Ryan; Fujita, Hidenori; Delasos, Lukas; Vojnic, Morana; Khodos, Inna; Yamada, Yukari; Ishizawa, Kota; Mattar, Marissa S.; Funabashi, Kaoru; Chang, Qing; Ohkubo, Shuichi; Yano, Wakako; Terada, Ryuichiro; Giuliano, Claudio; Lu, Yue Christine; Bonifacio, Annalisa; Kunte, Siddharth; Davare, Monika A.; Cheng, Emily H.; de Stanchina, Elisa; Lovati, Emanuela; Iwasawa, Yoshikazu; Ladanyi, Marc; Somwar, Romel Share Save
Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations Miyazaki, Isao; Odintsov, Igor; Ishida, Keiji; Lui, Allan J. W.; Kato, Masanori; Suzuki, Tatsuya; Zhang, Tom; Wakayama, Kentaro; Kurth, Renate I.; Cheng, Ryan; Fujita, Hidenori; Delasos, Lukas; Vojnic, Morana; Khodos, Inna; Yamada, Yukari; Ishizawa, Kota; Mattar, Marissa S.; Funabashi, Kaoru; Chang, Qing; Ohkubo, Shuichi; Yano, Wakako; Terada, Ryuichiro; Giuliano, Claudio; Lu, Yue Christine; Bonifacio, Annalisa; Kunte, Siddharth; Davare, Monika A.; Cheng, Emily H.; de Stanchina, Elisa; Lovati, Emanuela; Iwasawa, Yoshikazu; Ladanyi, Marc; Somwar, Romel Share Save
Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers Chatila, Walid K.; Walch, Henry; Hechtman, Jaclyn F.; Moyer, Sydney M.; Sgambati, Valeria; Faleck, David M.; Srivastava, Amitabh; Tang, Laura; Benhamida, Jamal; Ismailgeci, Dorina; Campos, Carl; Wu, Fan; Chang, Qing; Vakiani, Efsevia; de Stanchina, Elisa; Weiser, Martin R.; Widmar, Maria; Yantiss, Rhonda K.; Shah, Manish A.; Bass, Adam J.; Stadler, Zsofia K.; Katz, Lior H.; Mellinghoff, Ingo K.; Sethi, Nilay S.; Schultz, Nikolaus; Ganesh, Karuna; Kelsen, David; Yaeger, Rona Share Save
Molecular Characterization of Acquired Resistance to KRAS G12C-EGFR Inhibition in Colorectal Cancer Yaeger, Rona; Mezzadra, Riccardo; Sinopoli, Jenna; Bian, Yu; Marasco, Michelangelo; Kaplun, Esther; Gao, Yijun; Zhao, HuiYong; Paula, Arnaud Da Cruz; Zhu, Yingjie; Perez, Almudena Chaves; Chadalavada, Kalyani; Tse, Edison; Chowdhry, Sudhir; Bowker, Sydney; Chang, Qing; Qeriqi, Besnik; Weigelt, Britta; Nanjangud, Gouri J.; Berger, Michael F.; Der-Torossian, Hirak; Anderes, Kenna; Socci, Nicholas D.; Shia, Jinru; Murciano-Goroff, Yonina R.; Li, Bob; Christensen, James G.; Reis-Filho, Jorge S.; Solit, David B.; de Stanchina, Elisa; Lowe, Scott W.; Rosen, Neal; Misale, Sandra Share Save
ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1 Su, Wenjing; Mukherjee, Radha; Yaeger, Rona; Son, Jieun; Xu, Jianing; Na, Na; Timaul, Neilawattie Merna; Hechtman, Jaclyn; Paroder, Viktoriya; Lin, Mika; Mattar, Marissa; Qiu, Juan; Chang, Qing; Zhao, Huiyong; Zhang, Jonathan; Little, Megan; Adachi, Yuta; Han, Sae-Won; Taylor, Barry S.; Ebi, Hiromichi; Abdel-Wahab, Omar; de Stanchina, Elisa; Rudin, Charles M.; Janne, Pasi A.; McCormick, Frank; Yao, Zhan; Rosen, Neal Share Save
KRAS Mutants Upregulate Integrin? 4 to Promote Invasion and Metastasis in Colorectal Cancer Choi, Seo-Hyun; Kim, Jin K.; Chen, Chin-Tung; Wu, Chao; Marco, Michael R.; Barriga, Francisco M.; O'Rourke, Kevin; Pelossof, Raphael; Qu, Xuan; Chang, Qing; de Stanchina, Elisa; Shia, Jinru; Smith, J. Joshua; Sanchez-Vega, Francisco; Garcia-Aguilar, Julio Share Save
TAS0953/HM06 is effective in preclinical models of diverse tumor types driven by RET alterations Odintsov, Igor; Kurth, Renate I.; Ishizawa, Kota; Delasos, Lukas; Lui, Allan J. W.; Khodos, Inna; Hagen, Connor J.; Chang, Qing; Mattar, Marissa S.; Vojnic, Morana; Kunte, Siddharth; Bonifacio, Annalisa; Giuliano, Claudio; De Stanchina, Elisa; Cheng, Emily; Lovati, Emanuela; Ladanyi, Marc; Somwar, Romel Share Save
Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis Duan, Shanshan; Moro, Loredana; Qu, Rui; Simoneschi, Daniele; Cho, Hyunwoo; Jiang, Shaowen; Zhao, Huiyong; Chang, Qing; de Stanchina, Elisa; Arbini, Arnaldo A.; Pagano, Michele Share Save
Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules Singh, Kamini; Lin, Jianan; Lecomte, Nicolas; Mohan, Prathibha; Gokce, Askan; Sanghvi, Viraj R.; Jiang, Man; Grbovic-Huezo, Olivera; Burcul, Antonija; Stark, Stefan G.; Romesser, Paul B.; Chang, Qing; Melchor, Jerry P.; Beyer, Rachel K.; Duggan, Mark; Fukase, Yoshiyuki; Yang, Guangli; Ouerfelli, Ouathek; Viale, Agnes; de Stanchina, Elisa; Stamford, Andrew W.; Meinke, Peter T.; Raetsch, Gunnar; Leach, Steven D.; Ouyang, Zhengqing; Wendel, Hans-Guido Share Save
Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib Sun, Yuting; Meyers, Brooke A.; Czako, Barbara; Leonard, Paul; Mseeh, Faika; Harris, Angela L.; Wu, Qi; Johnson, Sarah; Parker, Connor A.; Cross, Jason B.; Di Francesco, Maria Emilia; Bivona, Benjamin J.; Bristow, Christopher A.; Burke, Jason P.; Carrillo, Caroline C.; Carroll, Christopher L.; Chang, Qing; Feng, Ningping; Gao, Guang; Gera, Sonal; Giuliani, Virginia; Huang, Justin K.; Jiang, Yongying; Kang, Zhijun; Kovacs, Jeffrey J.; Liu, Chiu-Yi; Lopez, Anastasia M.; Ma, Xiaoyan; Mandal, Pijus K.; McAfoos, Timothy; Miller, Meredith A.; Mullinax, Robert A.; Peoples, Michael; Ramamoorthy, Vandhana; Seth, Sahil; Spencer, Nakia D.; Suzuki, Erika; Williams, Christopher C.; Yu, Simon S.; Zuniga, Andy M.; Draetta, Giulio F.; Marszalek, Joseph R.; Heffernan, Timothy P.; Kohl, Nancy E.; Jones, Philip Share Save
Predicting Gemcitabine Delivery by 18F-FAC PET in Murine Models of Pancreatic Cancer Russell, James; Grkovski, Milan; O'Donoghue, Isabella J.; Kalidindi, Teja M.; Pillarsetty, Nagavarakishore; Burnazi, Eva M.; Kulick, Amanda; Bahr, Amber; Chang, Qing; LeKaye, H. Carl; de Stanchina, Elisa; Yu, Kenneth H.; Humm, John L. Share Save
Discovery of IACS-13909, an allosteric SHP2 inhibitor that overcomes multiple mechanisms underlying osimertinib resistance Sun, Yuting; Meyers, Brooke A.; Johnson, Sarah B.; Harris, Angela L.; Czako, Barbara; Cross, Jason B.; Leonard, Paul G.; Mseeh, Faika; Di Francesco, Maria E.; Parker, Connor A.; Wu, Qi; Bristow, Christopher A.; Burke, Jason P.; Carrillo, Caroline C.; Carroll, Christopher L.; Chang, Qing; Feng, Ningping; Gera, Sonal; Guang, Gao; Huang, Justin Kwang-Lay; Jiang, Yongying; Kang, Zhijun; Kovacs, Jeffrey J.; Ma, Xiaoyan; Mandal, Pijus K.; McAfoos, Timothy; Mullinax, Robert A.; Peoples, Michael D.; Ramamoorthy, Vandhana; Seth, Sahil; Suzuki, Erika; Williams, Christopher Conrad; Yu, Simon S.; Zuniga, Andy M.; Draetta, Giulio F.; Marszalek, Joseph R.; Heffernan, Timothy P.; Kohl, Nancy E.; Jones, Philip Share Save
Share Save
Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer (vol 114, pg E9066, 2017) Sansone, Pasquale; Savini, Claudia; Kurelac, Ivana; Chang, Qing; Amato, Laura Benedetta; Strillacci, Antonio; Stepanova, Anna; Iommarini, Luisa; Mastroleo, Chiara; Daly, Laura; Galkin, Alexander; Thakur, Basant Kumar; Soplop, Nadine; Uryu, Kunihiro; Hoshino, Ayuko; Norton, Larry; Bonafe, Massimiliano; Cricca, Monica; Gasparre, Giuseppe; Lyden, David; Bromberg, Jacqueline Share Save
Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer Sansone, Pasquale; Savini, Claudia; Kurelac, Ivana; Chang, Qing; Amato, Laura Benedetta; Strillacci, Antonio; Stepanova, Anna; Iommarini, Luisa; Mastroleo, Chiara; Daly, Laura; Galkin, Alexander; Thakur, Basant Kumar; Soplop, Nadine; Uryu, Kunihiro; Hoshinob, Ayuko; Norton, Larry; Bonafe, Massimiliano; Cricca, Monica; Gasparre, Giuseppe; Lyden, David; Bromberg, Jacqueline Share Save
JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors Gao, Sizhi P.; Chang, Qing; Mao, Ninghui; Daly, Laura A.; Vogel, Robert; Chan, Tyler; Liu, Shu Hui; Bournazou, Eirini; Schori, Erez; Zhang, Haiying; Brewer, Monica Red; Pao, William; Morris, Luc; Ladanyi, Marc; Arcila, Maria; Manova-Todorova, Katia; De Stanchina, Elisa; Norton, Larry; Levine, Ross L.; Altan-Bonnet, Gregoire; Solit, David; Zinda, Michael; Huszar, Dennis; Lyden, David; Bromberg, Jacqueline F. Share Save
Share Save
Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis Zhao, Libo; Wang, Xiaomin; Chang, Qing; Xu, Junying; Huang, Ying; Guo, Qiuyun; Zhang, Shaohui; Wang, Wenquan; Chen, Xiujuan; Wang, Jialing Share Save
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Not logged in.png){kind=icon}