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A positive allosteric modulator of the β1AR with antagonist activity for catecholaminergic polymorphic ventricular tachycardia Grogan, Alyssa; Perelli, Robin M.; Ahn, Seungkirl; Jiang, Haoran; Jyothidasan, Arun; Sood, Damini; You, Chongzhao; Israel, David I.; Shaginian, Alex; Chen, Qiuxia; Liu, Jian; Wang, Jialu; Steyaert, Jan; Kahsai, Alem W.; Landstrom, Andrew P.; Lefkowitz, Robert J.; Rockman, Howard A. Share Save
Structure and dynamics determine G protein coupling specificity at a class A GPCR Casiraghi, Marina; Wang, Haoqing; Brennan, Patrick C.; Habrian, Chris; Huebner, Harald; Schmidt, Maximilian F.; Maul, Luis; Pani, Biswaranjan; Bahriz, Sherif M. F. M.; Xu, Bing; Staffen, Nico; Assafa, Tufa E.; Chen, Bohan; White, Elizabeth; Sunahara, Roger K.; Inoue, Asuka; Xiang, Yang K.; Lefkowitz, Robert J.; Isacoff, Ehud Y.; Nucci, Nathaniel; Lerch, Michael T.; Kobilka, Brian K. Share Save
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How carvedilol does not activate β2-adrenoceptors Lefkowitz, Robert J.; Rockman, Howard A.; Shim, Paul J.; Liu, Samuel; Ahn, Seungkirl; Pani, Biswaranjan; Rajagopal, Sudarshan; Shenoy, Sudha K.; Bouvier, Michel; Benovic, Jeffrey L.; Liggett, Stephen B.; Ruffolo, Robert R.; Bristow, Michael R.; Packer, Milton Share Save
Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin Kahsai, Alem W.; Shah, Kunal S.; Shim, Paul J.; Lee, Mason A.; Shreiber, Bowie N.; Schwalb, Allison M.; Zhang, Xingdong; Kwon, Henry Y.; Huang, Li-Yin; Soderblom, Erik J.; Ahn, Seungkirl; Lefkowitz, Robert J. Share Save
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A Novel Allosteric Modulator Of The ß 1AR Identified By DNA-encoded Small Molecule Library Screening Demonstrates Unique Pharmacology And Function Grogan, Alyssa; Ahn, Seungkirl; Israel, David; Shaginian, Alex; Chen, Qiuxia; Liu, Jian; Wilkey, Max; Wang, Jialu; Kahsai, Alem; Lefkowitz, Robert J.; Rockman, Howard A. Share Save
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Unique Positive Cooperativity Between the fi-Arrestin-Biased β-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the β2-Adrenergic Receptor Pani, Biswaranjan; Ahn, Seungkirl; Rambarat, Paula K.; Vege, Shashank; Kahsai, Alem W.; Liu, Andrew; Valan, Bruno N.; Staus, Dean P.; Costa, Tommaso; Lefkowitz, Robert J. Share Save
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